Tomonori Takeuchi

The synaptic plasticity and memory hypothesis: encoding, storage and persistence

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

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The synaptic plasticity and memory hypothesis : encoding, storage and persistence. / Takeuchi, Tomonori; Duszkiewicz, Adrian J; Morris, Richard G M.

In: Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 369, No. 1633, 05.01.2014, p. 20130288.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

Harvard

Takeuchi, T, Duszkiewicz, AJ & Morris, RGM 2014, 'The synaptic plasticity and memory hypothesis: encoding, storage and persistence', Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 369, no. 1633, pp. 20130288. https://doi.org/10.1098/rstb.2013.0288

APA

Takeuchi, T., Duszkiewicz, A. J., & Morris, R. G. M. (2014). The synaptic plasticity and memory hypothesis: encoding, storage and persistence. Philosophical Transactions of the Royal Society B: Biological Sciences, 369(1633), 20130288. https://doi.org/10.1098/rstb.2013.0288

CBE

Takeuchi T, Duszkiewicz AJ, Morris RGM. 2014. The synaptic plasticity and memory hypothesis: encoding, storage and persistence. Philosophical Transactions of the Royal Society B: Biological Sciences. 369(1633):20130288. https://doi.org/10.1098/rstb.2013.0288

MLA

Takeuchi, Tomonori, Adrian J Duszkiewicz and Richard G M Morris. "The synaptic plasticity and memory hypothesis: encoding, storage and persistence". Philosophical Transactions of the Royal Society B: Biological Sciences. 2014, 369(1633). 20130288. https://doi.org/10.1098/rstb.2013.0288

Vancouver

Takeuchi T, Duszkiewicz AJ, Morris RGM. The synaptic plasticity and memory hypothesis: encoding, storage and persistence. Philosophical Transactions of the Royal Society B: Biological Sciences. 2014 Jan 5;369(1633):20130288. https://doi.org/10.1098/rstb.2013.0288

Author

Takeuchi, Tomonori ; Duszkiewicz, Adrian J ; Morris, Richard G M. / The synaptic plasticity and memory hypothesis : encoding, storage and persistence. In: Philosophical Transactions of the Royal Society B: Biological Sciences. 2014 ; Vol. 369, No. 1633. pp. 20130288.

Bibtex

@article{ec0d24abcd4141c283b24b6af0fef292,
title = "The synaptic plasticity and memory hypothesis: encoding, storage and persistence",
abstract = "The synaptic plasticity and memory hypothesis asserts that activity-dependent synaptic plasticity is induced at appropriate synapses during memory formation and is both necessary and sufficient for the encoding and trace storage of the type of memory mediated by the brain area in which it is observed. Criteria for establishing the necessity and sufficiency of such plasticity in mediating trace storage have been identified and are here reviewed in relation to new work using some of the diverse techniques of contemporary neuroscience. Evidence derived using optical imaging, molecular-genetic and optogenetic techniques in conjunction with appropriate behavioural analyses continues to offer support for the idea that changing the strength of connections between neurons is one of the major mechanisms by which engrams are stored in the brain. ",
keywords = "Dopamine/metabolism, Humans, Memory/physiology, Models, Neurological, Neuronal Plasticity/physiology, Optogenetics, Synapses/physiology",
author = "Tomonori Takeuchi and Duszkiewicz, {Adrian J} and Morris, {Richard G M}",
year = "2014",
month = jan,
day = "5",
doi = "10.1098/rstb.2013.0288",
language = "English",
volume = "369",
pages = "20130288",
journal = "Philosophical Transactions of the Royal Society B: Biological Sciences",
issn = "0962-8436",
publisher = "ROYAL SOC",
number = "1633",

}

RIS

TY - JOUR

T1 - The synaptic plasticity and memory hypothesis

T2 - encoding, storage and persistence

AU - Takeuchi, Tomonori

AU - Duszkiewicz, Adrian J

AU - Morris, Richard G M

PY - 2014/1/5

Y1 - 2014/1/5

N2 - The synaptic plasticity and memory hypothesis asserts that activity-dependent synaptic plasticity is induced at appropriate synapses during memory formation and is both necessary and sufficient for the encoding and trace storage of the type of memory mediated by the brain area in which it is observed. Criteria for establishing the necessity and sufficiency of such plasticity in mediating trace storage have been identified and are here reviewed in relation to new work using some of the diverse techniques of contemporary neuroscience. Evidence derived using optical imaging, molecular-genetic and optogenetic techniques in conjunction with appropriate behavioural analyses continues to offer support for the idea that changing the strength of connections between neurons is one of the major mechanisms by which engrams are stored in the brain.

AB - The synaptic plasticity and memory hypothesis asserts that activity-dependent synaptic plasticity is induced at appropriate synapses during memory formation and is both necessary and sufficient for the encoding and trace storage of the type of memory mediated by the brain area in which it is observed. Criteria for establishing the necessity and sufficiency of such plasticity in mediating trace storage have been identified and are here reviewed in relation to new work using some of the diverse techniques of contemporary neuroscience. Evidence derived using optical imaging, molecular-genetic and optogenetic techniques in conjunction with appropriate behavioural analyses continues to offer support for the idea that changing the strength of connections between neurons is one of the major mechanisms by which engrams are stored in the brain.

KW - Dopamine/metabolism

KW - Humans

KW - Memory/physiology

KW - Models, Neurological

KW - Neuronal Plasticity/physiology

KW - Optogenetics

KW - Synapses/physiology

U2 - 10.1098/rstb.2013.0288

DO - 10.1098/rstb.2013.0288

M3 - Review

C2 - 24298167

VL - 369

SP - 20130288

JO - Philosophical Transactions of the Royal Society B: Biological Sciences

JF - Philosophical Transactions of the Royal Society B: Biological Sciences

SN - 0962-8436

IS - 1633

ER -