Aarhus University Seal / Aarhus Universitets segl

Tinna V. Stevnsner

  1. 2020
  2. Published

    Endothelin-1 induces a strong pressor effect in ball pythons (Python regius). / Jensen, Maja Fuhlendorff; Nedergaard, Signe; Nielsen, Hang Nguyen; Skovgaard, Nini; Stevnsner, Tinna V.; Wang, Tobias.

    In: Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology, Vol. 241, 110620, 03.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. 2019
  4. Published

    DNA repair in plant mitochondria - a complete base excision repair pathway in potato tuber mitochondria. / Ferrando, Beatriz; Furlanetto, Ana L D M; Gredilla, Ricardo; Havelund, Jesper F; Hebelstrup, Kim H; Møller, Ian M; Stevnsner, Tinna.

    In: Physiologia Plantarum, Vol. 166, No. 2, 06.2019, p. 494-512.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Short-term high temperature treatment reduces viability and inhibits respiration and DNA repair enzymes in Araucaria angustifolia cells. / Furlanetto, Ana L.D.M.; Cadena, Silvia M.S.C.; Martinez, Glaucia R.; Ferrando, Beatriz; Stevnsner, Tinna; Møller, Ian M.

    In: Physiologia Plantarum, Vol. 166, No. 2, 06.2019, p. 513-524.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases. / Lautrup, Sofie; Caponio, Domenica; Cheung, Hoi Hung; Piccoli, Claudia; Stevnsner, Tinna; Chan, Wai Yee; Fang, Evandro F.

    In: Biogerontology, Vol. 20, No. 3, 06.2019, p. 255-269.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  7. 2018
  8. Published

    Two Cockayne Syndrome patients with a novel splice site mutation – clinical and metabolic analyses. / Sanchez-Roman, Ines; Lautrup, Sofie; Aamann, Maria Diget; Neilan, Edward G.; Østergaard, John R.; Stevnsner, Tinna.

    In: Mechanisms of Ageing and Development, Vol. 175, 10.2018, p. 7-16.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency. / Hou, Yujun; Lautrup, Sofie; Cordonnier, Stephanie; Wang, Yue; Croteau, Deborah L; Zavala, Eduardo; Zhang, Yongqing; Moritoh, Kanako; O'Connell, Jennifer F; Baptiste, Beverly A; Stevnsner, Tinna V; Mattson, Mark P; Bohr, Vilhelm A.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 8, 20.02.2018, p. E1876-E1885.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. 2017
  11. Published

    Role of Estrogen and Other Sex Hormones i Brain Aging. Neuroprotection and DNA Repair. / Zárate, Sandra; Stevnsner, Tinna V.; Gredilla, Ricardo.

    In: Frontiers in Aging Neuroscience, Vol. 9, 430, 22.12.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  12. Published

    Mitophagy in neurodegeneration and aging. / Fivenson, Elayne M; Lautrup, Sofie; Sun, Nuo; Scheibye-Knudsen, Morten; Stevnsner, Tinna; Nilsen, Hilde; Bohr, Vilhelm A; Fang, Evandro F.

    In: Neurochemistry International, Vol. 109, 10.2017, p. 202-209.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Isolation of functional mitochondria by inertial microfluidics - a new method to sort intracellular organelles from a small scale biological sample. / Tesauro, C.; Ferrando, B.; Ma, X.; Jepsen, M. L.; Ivarsen, Anne Kathrine; Frohlich, R.; Stevnsner, T.; Knudsen, B. R.; Ho, Y. P.

    In: R S C Advances, Vol. 7, 03.05.2017, p. 23735-23741.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Base Excision Repair in Aging. / Gredilla, Ricardo; Bohr, Vilhelm A; Stevnsner, Tinna V.

    The Base Excision Repair Pathway: Molecular Mechanisms and Role in Disease Development and Therapeutic Design. ed. / David M Wilson III. World Scientific, 2017. p. 773-803.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  15. 2016
  16. Published

    Aldring og død. / Stevnsner, Tinna V.

    Evolutionsbiologiske milepæle. ed. / Kai Finster; Tobias Wang; Finn Borchsenius; Freddy Bugge Christiansen. 1. ed. Aarhus Universitetsforlag, 2016. p. 199-211.

    Research output: Contribution to book/anthology/report/proceedingBook chapterEducation

  17. Published

    The Caenorhabditis elegans Werner syndrome protein participates in DNA damage checkpoint and DNA repair in response to CPT-induced double-strand breaks. / Hyun, Moonjung; Choi, Seoyun; Stevnsner, Tinna; Ahn, Byungchan.

    In: Cellular Signalling, Vol. 28, No. 3, 2016, p. 214-223.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Unilateral ureteral obstruction induces DNA repair by APE1. / Aamann, Maria Diget; Norregaard, Rikke; Kristensen, Marie Louise V; Stevnsner, Tinna; Frøkiær, Jørgen.

    In: American Journal of Physiology: Renal Physiology, Vol. 310, No. 8, 2016, p. F763-F776.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. 2015
  20. Published

    Nobelprisen i kemi 2015 : Når Kroppen reparerer DNA. / Lautrup, Sofie Hindkjær; Stevnsner, Tinna V.; Dahlgaard, Jørgen (Editor); Kjaer, Carsten Rabæk (Editor).

    In: Aktuel Naturvidenskab, Vol. 6, 12.2015, p. 28-33.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleCommunication

  21. Published

    Association study of FOXO3A SNPs and aging phenotypes in Danish oldest-old individuals. / Soerensen, Mette; Nygaard, Marianne; Dato, Serena; Stevnsner, Tinna; Bohr, Vilhelm; Christensen, Kaare; Christiansen, Lene.

    In: Aging Cell, Vol. 14, No. 1, 02.2015, p. 60-66.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance. / Maynard, Scott; Keijzers, Guido; Hansen, A-M; Osler, Merete; Molbo, Drude; Bendix, Laila; Møller, P; Loft, S; Moreno-Villanueva, M; Bürkle, A; Hvitby, C P; Schurman, S H; Stevnsner, T; Rasmussen, L J; Avlund, K; Bohr, V A.

    In: Acta Physiologica (Print), Vol. 213, No. 1, 01.2015, p. 156-170.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Regulation of the human Suv3 helicase on DNA by inorganic cofactors. / Venø, Susanne T; Witt, Marie B; Kulikowicz, Tomasz; Bohr, Vilhelm A; Stevnsner, Tinna.

    In: Biochimie, Vol. 108, 01.2015, p. 160-168.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Werner syndrome : Association of premature aging and cancer predisposition. / Ahn, Byungchan; Stevnsner, Tinna; Bohr, Vilhelm A.

    Molecular Oncology: Causes of Cancer and Targets for Treatment. ed. / Edward P. Gelmann; Charles L. Sawyers ; Frank J. Rauscher, III . Cambridge University Press, 2015. p. 423-433.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  25. 2014
  26. Published

    Hvorfor ældes vi? -når vores molekyler gør os gamle. / Stevnsner, Tinna V.

    25 søforklaringer : naturvidenskabelige fortællinger fra Søauditorierne. ed. / Carsten Rabæk Kjaer. Aarhus Universitetsforlag, 2014. p. 336-347.

    Research output: Contribution to book/anthology/report/proceedingBook chapterCommunication

  27. Published

    Human longevity and variation in DNA damage response and repair : study of the contribution of sub-processes using competitive gene-set analysis. / Debrabant, Birgit; Soerensen, Mette; Flachsbart, Friederike; Dato, Serena; Mengel-From, Jonas; Stevnsner, Tinna; Bohr, Vilhelm A; Kruse, Torben A; Schreiber, Stefan; Nebel, Almut; Christensen, Kaare; Tan, Qihua; Christiansen, Lene.

    In: European Journal of Human Genetics, Vol. 22, 12.02.2014, p. 1131-1136.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity. / Aamann, Maria Diget; Hvitby, Christina Poulsen; Popuri, Venkateswarlu ; Muftuoglu, Meltem; Lemminger, Lasse Pagh Brøgger; K. Skeby , Cecilie ; Keijzers, Guido; Ahn, Byungchan; Bjørås , Magnar ; Bohr, Vilhelm; Stevnsner, Tinna V.

    In: Mechanisms of Ageing and Development, Vol. 135, 01.2014, p. 1-14.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. 2013
  30. Published

    Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells. / Maynard, Scott; Keijzers, Guido; Gram, Martin; Desler, Claus; Bendix, Laila; Budtz-Jørgensen, Esben; Molbo, Drude; Croteau, Deborah L; Osler, Merete; Stevnsner, Tinna; Rasmussen, Lene Juel; Dela, Flemming; Avlund, Kirsten; Bohr, Vilhelm.

    In: Nature Communications, Vol. 5, No. 11, 11.11.2013, p. 850-864.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    Genetic and environmental influence on DNA strand break repair: a twin study. / Garm, Christian; Moreno-Villanueva, Maria ; Bürkle, Alexander; Larsen, Lisbeth Aagaard; Bohr, Vilhelm A; Christensen, Kaare; Stevnsner, Tinna V.

    In: Environmental and Molecular Mutagenesis, Vol. 54, No. 6, 07.2013, p. 414-420.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Regulatory interplay of Cockayne syndrome B ATPase and stress-response gene ATF3 following genotoxic stress. / Kristensen, Hans-Ulrik Svejstrup; Epanchintsev, Alexey; Rauschendorf, Marc-Alexander; Laugel, Vincent; Stevnsner, Tinna; Bohr, Vilhelm A; Coin, Frederic; Egly, Jean-Marc.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, No. 25, 18.06.2013, p. 2261-2270.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Multiple interaction partners for Cockayne syndrome proteins : Implications for genome and transcriptome maintenance. / Aamann, Maria D; Muftuoglu, Meltem; Bohr, Vilhelm A; Stevnsner, Tinna.

    In: Mechanisms of Ageing and Development, Vol. 134, No. 5-6, 05.2013, p. 212-224.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  34. Published

    Age and gender effects on DNA strand break repair in peripheral blood mononuclear cells. / Garm, Christian; Moreno-Villanueva, Maria; Bürkle, Alexander; Petersen, Inge; Bohr, Vilhelm A.; Christensen, Kaare; Stevnsner, Tinna V.

    In: Aging Cell, Vol. 12, No. 1, 02.2013, p. 56-66.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity. / Soerensen, Mette; Dato, Serano; Tan, Qihua; Thinggaard, Mikael; Kleindorp, Rabea; Beekman, Marian; Suchiman, H Eka D; Jacobsen, Rune; McGue, Matt; Stevnsner, Tinna ; Bohr, Vilhelm A; de Craen, Anton J M; Westendorp, Rudi G J; Schreiber, Stefan; Slagboom, P Eline; Nebel, Almut; Vaupel, James W; Christensen, Kaare; Christiansen, Lene.

    In: Age (Omaha), Vol. 35, No. 2, 2013, p. 487-500.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. 2012
  37. Published

    Cancer and Longevity-Is There a Trade-off? A Study of Cooccurrence in Danish Twin Pairs Born 1900-1918. / Christensen, Kaare; Pedersen, Jacob K; Hjelmborg, Jacob V B; Vaupel, James W.; Stevnsner, Tinna V.; Holm, Niels Vilstrup; Skytthe, Axel.

    In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, Vol. 67A, No. 5, 05.2012, p. 489-494.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes : cross sectional and longitudinal studies. / Soerensen, Mette; Dato, Serena; Tan, Qihua; Thinggaard, Mikael; Kleindorp, Rabea; Beekman, Marian; Jacobsen, Rune; Suchiman, H Eka D; de Craen, Anton J M; Westendorp, Rudi G J; Schreiber, Stefan; Stevnsner, Tinna; Bohr, Vilhelm A; Slagboom, P Eline; Nebel, Almut; Vaupel, James W.; Christensen, Kaare; McGue, Matt; Christiansen, Lene.

    In: Experimental Gerontology, Vol. 47, No. 5, 05.2012, p. 379-387.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: a cross-sectional and longitudinal analysis. / Sørensen, Mette; Thinggaard, Mikael; Nygaard, Marianne; Dato, Serena; Tan, Qihua; Hjelmborg, Jacob; Andersen-Ranberg, Karen; Stevnsner, Tinna V.; Bohr, Vilhelm; Kimura, Masayuki; Aviv, Abraham; Christensen, Kaare; Christiansen, Lene.

    In: Aging Cell, Vol. 11, No. 2, 04.2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    Mitochondrial base excision repair assays. / Gredilla, Ricardo; Stevnsner, Tinna.

    Methods in Molecular Biology : DNA Repair Protocols. ed. / Lone Bjergbæk. Vol. 920 Humana Press, 2012. p. 289-304 (Methods in Molecular Biology).

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  41. Published

    Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer's disease. / Diaz, Ricardo Gredilla; Weissman, Lior; Yang, JL; Bohr, Vilhelm; Stevnsner, Tinna V.

    In: Neurobiology of Aging, Vol. 33, No. 4, 2012, p. 694-707.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    Nuclear and mitochondrial DNA repair in selected eukaryotic aging model systems. / Gredilla, Ricardo; Garm, Christian; Stevnsner, Tinna.

    In: Oxidative Medicine and Cellular Longevity, Vol. 2012, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. 2011
  44. Published

    WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes. / Patro, B.S.; Frøhlich, R.; Bohr, V.A.; Stevnsner, T.

    In: Journal of Cell Science, Vol. 124, No. 23, 01.12.2011, p. 3967-3979.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    DNA repair deficiency in neurodegeneration. / Jeppesen, Dennis Kjølhede; Bohr, Vilhelm; Stevnsner, Tinna V.

    In: Progress in Neurobiology, Vol. 30, No. 94, 04.2011, p. 166-200.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  46. Published

    The Human Suv3 Helicase Interacts with Replication Protein A and Flap Endonuclease 1 in the Nucleus. / Venø, Susanne Trillingsgaard; Kulikowicz, Thomasz; Pestana, Cezar; Stepien, Piotr; Stevnsner, Tinna V.; Bohr, Vilhelm.

    In: Biochemical Journal, 2011.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-IDNA covalent complexes. / Patro, Birija Sankar; Hougaard, Rikke Frøhlich; Bohr, Vilhelm; Stevnsner, Tinna V.

    In: Journal of Cell Science, Vol. 124, 2011, p. 3967-3979.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  48. 2010
  49. Published

    Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data. / Sørensen, Mette; Dato, S.; Christensen, Kaare; McGue, M.; Stevnsner, Tinna V.; Bohr, Vilhelm; Christiansen, Lene.

    In: Aging Cell, Vol. 9, No. 6, 12.2010, p. 1010-1017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    Regulation of WRN function and activity by sumoylation during the DNA damage response. / Hougaard, Rikke Frøhlich; Jeppesen, Dennis Kjølhede; Bohr, Vilhelm; Stevnsner, Tinna V.

    2010. Abstract from The interface between the Ubiquitin Family and the DNA damage Response, EMBO, Croatia.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  51. Published

    Mitochondrial DNA repair and association with aging- an update. / Diaz, Ricardo Gredilla; Bohr, Vilhelm; Stevnsner, Tinna V.

    In: Experimental Gerontology, Vol. 45, No. 7-8, 08.2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  52. Published

    Cockayne Syndrome group B protein promotes mtDNA stability by maintaining the BER association with the mitochondrial membrane. / Aamann, Maria Aaen Diget; Sørensen, M.; Hvitby, Christina Poulsen; Bergquist, B.; Muftuoglu, Meltem; Tian, J.; de Souza-Pinto, N.C.; Scheibye-Knudsen, M.; Wilson III, D.M.; Stevnsner, Tinna V.; Bohr, Vilhelm.

    In: F A S E B Journal, Vol. 24, No. 7, 2010, p. 2334-46.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Differential age-related changes in mitochondrial DNA repair activities in mouse brain regions. / Gredilla, Ricardo; Garm, Christian; Holm, Rikke; Bohr, Vilhelm A; Stevnsner, Tinna.

    In: Neurobiology of Aging, Vol. 31, No. 6, 2010, p. 993-1002.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  54. Published

    Mitochondrial helicases and mitochondrial genome maintenance. / Aamann, Maria Diget; de Souza-Pinto, Nadja C; Kulikowicz, Tomasz; Stevnsner, Tinna V; Bohr, Vilhelm A.

    In: Mechanisms of Ageing and Development, Vol. 131, No. 7-8, 2010, p. 503-10.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  55. 2009
  56. Published

    Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase. / Muftuoglu, Meltem; Souza-Pinto, NC; Dogan, A; Aamann, Maria Aaen Diget; Stevnsner, Tinna V.; Rybanska, I; Kirkali, G.; Dizdaroglu, M.; Bohr, Vilhelm.

    In: Journal of Biological Chemistry, Vol. 284, No. 14, 29.01.2009, p. 9270-9279.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. Published

    A potential impact of DNA repair on ageing and lifespan in the ageing model organism Podospora anserine: decrease in mitochondrial DNA repair activity during ageing. / Sørensen, Mette; Diaz, Ricardo Gredilla; Müller-Ohldach, Mathis; Werner, Alexander; Bohr, Vilhelm; Osiewacz, Heinz D; Stevnsner, Tinna V.

    In: Mechanisms of Ageing and Development, Vol. 130, No. 8, 2009, p. 487-496.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  58. Published

    Cockayne Syndrome Group B Protein and Chromatin Structure. / Aamann, Maria Aaen Diget; Stevnsner, Tinna V.

    Molecular Mechanisms of Cockayne Syndrome. Landes Bioscience, 2009. p. Chap. 3.

    Research output: Contribution to book/anthology/report/proceedingBook chapterEducation

  59. Published

    Cockayne syndrome group B protein is engaged in processing of DNA adducts of lipid peroxidation product trans-4-hydroxy-2-nonenal. / Maddukuri, L; Speina, E; Christiansen, M; Dudzinska, D; Zaim, J; Obtulowicz, T; Kabaczyk, S; Komisarski, M; Bukowy, Z; Szczegielniak, J; Wojcik, A; Kusmierek, J; Stevnsner, Tinna V.; Bohr, Vilhelm; Tudek, B.

    In: Mutation Research - Reviews, Vol. 666, 2009, p. 23-31.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  60. Published

    Cockayne syndrome group B protein is engaged in processing of DNA adducts of lipid peroxidation product trans-4-hydroxy-2-nonenal. / Maddukuri, Lena; Speina, Elżbieta; Christiansen, Mette; Dudzinska, Dominika; Zaim, Jolanta; Obtułowicz, Tomasz; Kabaczyk, Sylwia; Komisarski, Marek; Bukowy, Zuzanna; Szczegielniak, Jadwiga; Wójcik, Andrzej; Kuśmierek, Jaroslaw T.; Stevnsner, Tinna V.; Bohr, Vilhelm; Tudek, Barbara.

    In: Mutation Research - Reviews, Vol. 666, No. 1-2, 2009, p. 23-31.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  61. Published

    Novel DNA mismatch-repair activity involving YB-1 in human mitochondria. / de Souza-Pinto, Nadja; A. Mason, Penelope; Hashiguchi, K; Weismann, Lior; Tian, J; Guay, D; Lebel, M; Stevnsner, Tinna V.; Rasmussen, Lene Juel; Bohr, Vilhelm.

    In: D N A Repair, Vol. 8, No. 6, 2009, p. 704-719.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  62. Published

    The Mn-superoxide dismutase single nucleotide polymorphism rs4880 and the glutathione peroxidase 1 single nucleotide polymorphism rs1050450 are associated with aging and longevity in the oldest old. / Sørensen, Mette; Christensen, Kaare; Stevnsner, Tinna V.; Christiansen, Lene.

    In: Mechanisms of Ageing and Development, Vol. 130, No. 5, 2009.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  63. 2008
  64. Published

    Age-related changes in DNA repair in mouse cerebella mitochondria. / Diaz, Ricardo Gredilla; Garm, Christian Hasselbalch; Jensen, Rikke Holm; Bohr, Vilhelm; Stevnsner, Tinna V.

    2008. Poster session presented at 1st International Genome Dynamics in Neuroscience Conference, Oslo, Norway.

    Research output: Contribution to conferencePosterResearch

  65. Published

    Aging-from molecules to populations. / Sander, Miriam; Avlund, Kirsten; Lauritzen, Martin; Gottlieb, Tina; Halliwell, Barry; Stevnsner, Tinna; Wewer, Ulla; Bohr, Vilhelm A.

    In: Mechanisms of Ageing and Development, Vol. 129, No. 10, 2008, p. 614-23.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  66. Published

    Aspects of Cockayne Syndrome group B protein functions and interactions. / Bohr, Vilhelm; Thorslund, Tina; Christiansen, Mette; Muftuoglu, Meltem; Stevnsner, Tinna V.

    2008. Poster session presented at 3rd International Conference on Functional Genomics of Ageing, Palermo, Sicily, Italy.

    Research output: Contribution to conferencePosterResearch

  67. Published

    DNA repair, mitochondria and Ageing. / Diaz, Ricardo Gredilla; Garm, Christian Hasselbalch; Bohr, Vilhelm; Stevnsner, Tinna V.

    2008. Poster session presented at 2nd International Genome Dynamics in Neuroscience Conference, Asilomar Conference center, Pacific Groove, United States.

    Research output: Contribution to conferencePosterResearch

  68. Published

    Mitochondrial DNA Repair in Mammalian Brain during Lifespan. / Simonsen, Casper; Patro, Birija Sankar; Diaz, Ricardo Gredilla; Osiewacz, H.D.; Bohr, Vilhelm; Stevnsner, Tinna V.

    2008. Poster session presented at MiMage/LINK-AGE Joint Summer School, Les Diablerets, Switzerland.

    Research output: Contribution to conferencePosterResearch

  69. Published

    Mitochondrial DNA, base excision repair and neurodegeneration. / de Souza-Pinto, Nadja C.; Wilson III, David M.; Stevnsner, Tinna V.; Bohr, Vilhelm.

    In: D N A Repair, Vol. 7, 2008, p. 1098-1109.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  70. Published

    The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging. / Stevnsner, Tinna V.; Muftuoglu, Meltem; Aamann, Maria Aaen Diget; Bohr, Vilhelm.

    In: Mechanisms of Ageing and Development, Vol. 129, No. 7-8, 2008, p. 441-448.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  71. Published

    WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand. / Bukowy, Zuzanna Katarzyna; A. Harrigan, Jeanine; A. Ramsden, Dale; Tudek, Barbara; Bohr, Vilhelm; Stevnsner, Tinna V.

    In: Nucleic Acids Research, 2008, p. 1-13.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  72. 2007
  73. Published

    Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase. / Imam, S.Z.; Indig, F.E.; Cheng, W.H.; Saxena, S.P.; Stevnsner, Tinna V.; Kufe, T.; Bohr, Vilhelm.

    In: Nucleis Acid Res., Vol. 35, 2007, p. 4941-4951.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  74. Published

    Mitochondria as determinant of nucleotide metabolism and chromosomal stability. / Desler, C.; Munch-Petersen, B.; Stevnsner, Tinna V.; Matsui, S.-I.; Kulawiec, M.; Singh, K.; Rasmussen, L.J.

    In: Mutation Research - Reviews, Vol. 625, 2007, p. 112-124.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  75. Published

    Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal. / Frøhlich, Rikke F; Veigaard, Christopher; Andersen, Félicie Faucon; McClendon, A.K.; Gentry, A.K.; Andersen, Anni Hangaard; Osherroff, N.; Stevnsner, Tinna V.; Knudsen, Birgitta R.

    In: Nucleic Acid Res., Vol. 35, 2007, p. 6170-6180.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  76. 2006
  77. Published

    Cockayne syndrome group B protein has novel strand annealing and exchange activities. / Muftuoglu, M.; Sharma, S.; Thorslund, Tina; Stevnsner, Tinna V.; Sørensen, Martin Mark; Brosh, R.M.; Bohr, Vilhelm.

    In: Nucleic Acids Res. , Vol. 34, 2006, p. 295-304.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  78. Published

    DNA repair, mitochondria, and neurodegeneration. / Weissman, Lior; de Souza-Pinto, Nadja C; Stevnsner, Tinna V.; Bohr, Vilhelm.

    In: Neuroscience, No. 145, 2006, p. 1318-1329.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  79. Published

    DNA-reparation - en grundlæggende faktor i aldring og cancerudvikling. / Rasmussen, Lene Juel; Stevnsner, Tinna V.; Bohr, Vilhelm.

    In: Ugeskrift for Laeger, Vol. 168, No. 24, 2006, p. 2332-2335.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  80. Published

    Human premature aging diseases: molecular biology to clinical diagnosis. / Gan, D.D.; Hedayati, M.; Stevnsner, Tinna V.; Bohr, Vilhelm.

    Prevention and treatment of age related diseases. ed. / Suresh Rattan; M. Kassem. Springer, 2006.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearch

  81. 2005
  82. Published

    Gene expression responses to DNA damage are altered in human aging and in Werner Syndrome. / Kyng, KJ; May, Alfred; Stevnsner, Tinna; Becker, Kevin G; Kølvrå, Steen; Bohr, Vilhelm A.

    In: Oncogene, Vol. 24, No. 32, 28.07.2005, p. 5026-42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  83. Published

    Cooperation of the Cockayne syndrome group B protein and PARP-1 in the response to oxidative damage. / Thorslund, Tina; Stevnsner, Tinna V.; Bohr, Vilhelm.

    2005. Poster session presented at Benzon Symposium 52: Cellular Responses to DNA Damage, København, Denmark.

    Research output: Contribution to conferencePosterResearch

  84. Published

    Cooperation of the Cockayne syndrome group B protein and poly (ADP-ribose) polymerase 1 in the response to oxidative stress. / Thorslund, Tina; von Kobbe, C.; Harrigan, J.A.; Indig, F.E.; Christiansen, Mette; Stevnsner, Tinna V.; Bohr, Vilhelm.

    In: Molecular and Cellular Biology, Vol. 25, 2005, p. 7625-7236.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  85. Published

    Gene expression responses to DNA damage are alterd in human aging and in Werner Syndrome. / Kyng, Kasper; May, A.; Stevnsner, Tinna V.; Becker, K.G.; Kølvraa, Steen; Bohr, Vilhelm.

    In: Oncogene, Vol. 24, 2005, p. 5026-5042.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  86. Published

    Identification of a physical and functional interaction between CSB and PARP-1A novel implication of CSB in the cellular response to oxidative DNA damage? / Thorslund, Tina; von Kobbe, Cayetano; Harrigan, Jeanine A.; Bohr, Vilhelm; Stevnsner, Tinna V.

    2005. Poster session presented at Keystone Symposia, Genome Instability and Repair, Taos, NM, United States.

    Research output: Contribution to conferencePosterResearch

  87. Published

    Mitochondrial repair of oxidative damage and changes with aging. / Stevnsner, Tinna V.; Jensen, Anne; Thorslund, Tina; deSouza-Pinto, Nadja; Bohr, Vilhelm.

    2005. Poster session presented at Benzon Symposium 52: Cellular Responses to DNA Damage, København, Denmark.

    Research output: Contribution to conferencePosterResearch

  88. Published

    The Cockayne syndrome group B protein is a functional dimer. / Christiansen, Mette; Thorslund, Tina; Jochimsen, Bjarne; Bohr, Vilhelm; Stevnsner, Tinna V.

    In: FEBS J., Vol. 272, 2005, p. 4306-4314.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  89. 2004
  90. Published

    Aldringens molekylærbiologi. / Stevnsner, T.; Thorslund, T.; Bohr, Vilhelm.

    In: Aktuel Naturvidenskab, Vol. 1, 2004, p. 4-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  91. Published

    Forskning i aldringens molekylærbiologi. / Stevnsner, T.; Bohr, Vilhelm.

    Ny aldringsforskning - resultater og perspektiver. ISBN 87-90651-39-1. ed. Ældreforum, 2004. p. 19-23.

    Research output: Contribution to book/anthology/report/proceedingReport chapterResearch

  92. 2003
  93. Published

    Cockaynes syndrome group B cellular and biochemical functions. / Licht, C.; Stevnsner, T.; Bohr, Vilhelm.

    In: Am. J. Hum. Gen., Vol. 73, 2003, p. 1217-1239.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  94. Published

    Dansk Center for Molekylær Gerontologi. / Clark, B.; Rattan, S.; Stevnsner, T.

    Aarhus Universitets Forskningsfond: Årsberetning 2002. Afdeling for Kunsthistorie, Institut for Æstetiske Fag, Aarhus Universitet, 2003. p. 18-19.

    Research output: Contribution to book/anthology/report/proceedingBook chapterCommunication

  95. Published

    Functional consequences of mutations in the conserved SF2 motifs and post-translational phosphorylation of the CSB protein. / Christiansen, Mette; Stevnsner, Tinna V.; Modin, C.; Martensen, P.M.; Brosh Jr., R. M.; Bohr, Vilhelm.

    In: Nucleic Acids Res. , Vol. 31, No. 3, 2003, p. 963-973.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  96. Published

    Functional consequences of mutations in the conserved SF2 motifs and posttranslational phosphorylation of the CSB protein. / Christiansen, M.; Stevnsner, T.; Modin, C.; Martensen, P.M.; Brosh Jr., R.M.; Bohr, Vilhelm.

    In: Nucl. Acids Res., Vol. 31, 2003, p. 963-973.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  97. Published

    Mammalian OGG1 incises 8-oxoadenine opposite cytosine in nuclei and mitochondria, while a different glycosylase incises 8-oxoadenine opposite guanine in nuclei. / Jensen, A.; Calvayrac, G.; Karahalil, B.; Bohr, Vilhelm; Stevnsner, T.

    In: Journal of Biological Chemistry, Vol. 278, 2003, p. 19541-19548.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  98. 2002
  99. Published

    Global genome repair of 8-oxoG in hamster cells requires a functional CSB gene product. / Sunesen, M.; Stevnsner, T.; Brosh Jr., R.M.; Dianov, G.; Bohr, Vilhelm.

    In: Oncogene, Vol. 21, 2002, p. 3571-3578.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  100. Published

    Mitochondrial repair of 8-oxoguanine and changes with aging. / Stevnsner, T.; Thorslund, T.; de Souza-Pinto, N.C.; Bohr, Vilhelm.

    In: Experimental Gerontology, Vol. 37, 2002, p. 1189-1196.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  101. Published

    Mitochondrial repair of 8-oxoguanine is deficient in Cockayne Syndrome group B. / Stevnsner, T.; Nyaga, S.; de Souza-Pinto, N.C.; van der Horst, G.T.J.; Gorgels, T.G.M.F.; Hogue, B.A.; Thorslund, T.; Bohr, Vilhelm.

    In: Oncogene, Vol. 21, 2002, p. 8675-8682.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  102. Published

    Mitochrondrial DNA repair of oxidative damage in mammalian cells. / Bohr, Vilhelm; Stevnsner, T.; Souza-Pinto, N.

    In: Gene, Vol. 286, 2002, p. 127-134.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  103. Published

    Repair of 8-oxoG is slower in endogenous nuclear genes than in mitochondrial DNA and is without strand bias. / Thorslund, T.; Sunesen, M.; Bohr, Vilhelm; Stevnsner, T.

    In: D N A Repair, Vol. 1, 2002, p. 261-273.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  104. Published

    The tumor suppressor protein p53 stimulates the formation of the human topoisomerase I double cleavage complex in vitro. / Søe, K.; Hartmann, H.; Schlott, B.; Stevnsner, T.; Grosse, F.

    In: Oncogene, Vol. 21, 2002, p. 6614-6623.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  105. 2001
  106. Published

    A human topoisomerase I cleavage complex stimulates the formation of a nearby additional cleavage complex in vitro. / Søe, K.; Dianov, G.; Nasheuer, H.-P.; Bohr, Vilhelm; Grosse, F.; Stevnsner, T.

    In: Nucl. Acids Res., Vol. 29, 2001, p. 3195-3103.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  107. Published

    BER in nuclear and mitochondrial DNA. / Dianov, G.; Souza-Pinto, N.; Nyaga, S.G.; Thybo, T.; Stevnsner, T.; Bohr, Vilhelm.

    In: Prog. Nucl. Acids Res. Mol. Biol., Vol. 68, 2001, p. 285-298.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  108. Published

    Repair of 8-oxodeoxyguanosine lesions in mitochrondrial DNA depends on oxoguanine DNA glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial DNA of OGG1-defective mice. / de Souza-Pinto, N.C.; Eide, L.; Hogue, B.A.; Thybo, T.; Stevnsner, T.; Klungland, A.; Seeberg, E.; Bohr, Vilhelm.

    In: Cancer Research, Vol. 61, 2001, p. 5378-5381.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  109. 2000
  110. Published

    Gene-specific DNA repair of pyrimidine dimers does not decline during cellular aging in vitro. / Christiansen, Mette; Stevnsner, T.; Bohr, Vilhelm; Clark, B.F.C.; Rattan, Suresh.

    In: Exp. Cell Res., Vol. 256, 2000, p. 308-314.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  111. Published

    Gene-specific DNA repair of pyrimidine dimers does not decline during cellular aging in vitro. / Christiansen, Mette; Stevnsner, Tinna V.; Bohr, Vilhelm; Clark, B. F.; Rattan, Suresh.

    In: Exp. Cell Res., Vol. 256, No. 1, 2000, p. 308-314.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  112. Published

    Molecular characterization of an acidic region deletion mutant of Cockayne syndrome group B protein. / Sunesen, M.; Selzer, R.R.; Brosh, R.M.Jr.; Balajee, A.S.; Stevnsner, T.; Bohr, V.A.

    In: Nucl. Acids Res., Vol. 28, 2000, p. 3151-3159.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review