Projects per year
Personal profile
External positions
CEO, NMD Pharma A/S
1 May 2015 → …
Keywords
- Physiology
- skeletal muscle
- cardiac muscle
- Electrophysiology
- neuromuscular disease
- drug development
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Dive into the research topics where Thomas Holm Pedersen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 2 Active
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Influence of chloride channel function on membrane excitability in skeletal muscle
Hyldkrog, H. G. (Participant), Pedersen, T. H. (Participant) & Riisager, A. (Participant)
20/06/2013 → …
Project: Research
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Excitation-induced calcium uptake in rat skeletal muscle
Hyldkrog, H. G. (Participant) & Pedersen, T. H. (Participant)
15/03/2012 → …
Project: Research
Research output
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Neuromuscular transmission deficits in patients with CMT and ClC-1 inhibition in CMT animal models
Grønnebæk, T. S., Haahr-Lillevang, H., Skov, M., Kelly, K., Kerr, N. R., Viteri, J. A., Jaworek, A., Bartlett, A., Bold, J., Hutchison, J., Quiroz, J., Tankisi, H., Pedersen, T. H., Andersen, H. & Arnold, W. D., Feb 2025, In: Annals of clinical and translational neurology. 12, 2, p. 320-331 12 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
Safety, Pharmacokinetics, and Pharmacodynamics of a First-in-Class ClC-1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial
Ruijs, T. Q., de Cuba, C. M. K. E., Heuberger, J. A. A. C., Hutchison, J., Bold, J., Grønnebæk, T. S., Jensen, K. G., Chin, E., Quiroz, J. A., Petersen, T. K., Flagstad, P., de Kam, M. L., van Esdonk, M. J., Klaassen, E., Doll, R. J., Koopmans, I. W., de Goede, A. A., Aulin, L. B. S., Pedersen, T. H. & Groeneveld, G. J., Mar 2025, In: Clinical Pharmacology and Therapeutics. 117, 3, p. 768-778 11 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access1 Citation (Scopus) -
ClC-1 Inhibition as a Mechanism for Accelerating Skeletal Muscle Recovery After Neuromuscular Block in Rats
Skals, M., Broch-Lips, M., Skov, M. B., Riisager, A., Ceelen, J., Nielsen, O. B., Brull, S. J., de Boer, H. D. & Pedersen, T. H., Dec 2024, In: Nature Communications. 15, 1, 9289.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
Role of recovery of acetylcholine release in compromised neuromuscular junction function
Winther, J. B., Morgen, J. J., Skov, M., Broch-Lips, M. G., Nielsen, O. B., Overgaard, K. & Pedersen, T. H., Mar 2024, In: Neuromuscular Disorders. 36, p. 48-59 12 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
2 Citations (Scopus) -
The ClC-1 chloride channel inhibitor NMD670 improves skeletal muscle function in rat models and patients with myasthenia gravis
Skov, M., Ruijs, T. Q., Grønnebæk, T. S., Skals, M., Riisager, A., Winther, J. B., Dybdahl, K. L. T., Findsen, A., Morgen, J. J., Huus, N., Broch-Lips, M., Nielsen, O. B., de Cuba, C. M. K. E., Heuberger, J. A. A. C., de Kam, M. L., Tannemaat, M., Verschuuren, J. J. G. M., Knutsen, L. J. S., Kelly, N. M. & Jensen, K. G. & 10 others, , Mar 2024, In: Science translational medicine. 16, 739Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
8 Citations (Scopus)
Activities
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Regulation of skeletal muscle excitability: role in muscle fatigue
Pedersen, T. H. (Lecturer)
25 Sept 2010Activity: Presentations, memberships, ownership and other activities › Lecture and oral contribution
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Myonak Conference
Pedersen, T. H. (Participant)
13 Jun 2007 → 17 Jun 2007Activity: Participating in or organising an event types › Participation in or organisation af a conference
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Skeletal muscle excitability: role of the resting membrane conductance
Pedersen, T. H. (Lecturer)
13 Jun 2007Activity: Presentations, memberships, ownership and other activities › Lecture and oral contribution
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Post Doc at Cambridge University
Pedersen, T. H. (Participant)
1 Mar 2007 → 30 Jun 2007Activity: Presentations, memberships, ownership and other activities › Other
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Skeletal muscle excitability: role of the resting membrane conductance
Pedersen, T. H. (Lecturer)
15 Mar 2006Activity: Presentations, memberships, ownership and other activities › Lecture and oral contribution
Prizes
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Tildelt en Ung Eliteforskerpris af det Frie Forskningsråd
Pedersen, T. H. (Recipient), 25 Jan 2007
Prize: Prizes, scholarships, distinctions