Thomas Vorup-Jensen

Professor

Profile photo

Thomas Vorup-Jensen

Professor

  • Department of Biomedicine - Forskning og uddannelse, Skou-bygningen
  • Department of Biomedicine - Forskning og uddannelse, Skou-bygningen
Postal address:
Høegh-Guldbergs Gade 10
1115, 230
8000
Aarhus C
Denmark
Postal address:
Høegh-Guldbergs Gade 10
8000
Aarhus C
Denmark

Email: vorup-jensen@biomed.au.dk

Mobile: +4521489781

Phone: +4521489781

Curriculum Vitae

 

1. Education (date for degree award in brackets)

1996(24 April):   MSc (cand.scient.) in chemistry-biotechnology, Aarhus University (AU).

2000(22 May):    PhD, AU. “Synthesis of Recombinant MASP and MBL”. Supervisor: J.C. Jensenius

2014(5 Sept.):     DMSc (dr. med), AU. “On the Roles of Polyvalent binding in Immune Recognition”

2015:                “Leading the Virtual Company”, Pasteur Program, Harvard Business School

 

2. Current & Recent Employments

2001-2005:        Research Fellow, Dept. of Pathology, Harvard Medical School, Boston, MA in the laboratory of Professor Timothy A. Springer

2005-2012:        Associate Professor, Dept. of Biomedicine

2012-2017:        Professor (MSO) in Biophysical Immunology, Dept. of Biomedicine, AU

2017-:                Professor in Biophysical Immunology, Dept. of Biomedicine, AU

 

3. Awards

2007:                 “Dr.med. Niels Kjærgaards og Overlæge, dr.med. Hans Peter Brasch Kjærgaards Mindelegat”. Awarded by Rektor (president) of AU.

 

4. Recent Leadership Experience

2005-:              Principle Investigator and Head, Biophysical Immunol. Lab., Dept. of Biomedicine, AU.

2014-:              Head, Graduate Program in Biomedicine, AU.

2017-:              Founding Chairman (2017) and Member (2018-) and Member, Medical Innovation Day 2017 Organizing Committee.

2017-:              Member, Advisory Board, Doktoratskolleg Molecular Fundamentals of Inflammation (DK-MOLIN), Medical University of Graz, Graz, Austria

2019-20:          Member, Steering Committee, BioPeople – Denmark’s Life Science Cluster

 

5. Key Research Interests

Innate immunity; immune cell adhesion to extracellular constituents; immunotherapy and biological therapy, application of biophysical methods in molecular immunology and cell biology; biomedical applications of nanoscience.

 

6. Research training (2005-21)

Four postdoctoral employees. Seventeen PhD Students: Main supervisor for 7 students; co-supervisor for 10 students (1 pending completion). Supervisor for 17 MSc, ERASMUS, and Medical Research Year Students (1 pending completion). Supervisor for 10 experimental B.Sc. thesis students.

 

7. Publication statistics

Seventy-seven peer-reviewed journal publications, including publications in Nature (1), J. Exp. Med. (1), PNAS (3), J. Biol. Chem. (2), and J. Immunol. (13), 14 contributions to book or scientific anthologies, 8 contributions to science communication. Two granted US patents. My publications are cited more than 5,300 times (Google Scholar: http://scholar.google.dk/citations?user=bX5FHeAAAAAJ&hl=en) and my Hirsch index is 34. Most cited publication has more than 950 citations (June 2021).

Recent Activities

Mannan-binding lectin, a superoligomeric DNA scavenger

Thomas Vorup-Jensen (Lecturer)

21 Feb 2023

Protein agregates and inflammation

Thomas Vorup-Jensen (Lecturer)

10 Feb 2023

1st LightRail Seminar

Thomas Vorup-Jensen (Organizer)

8 Feb 2023

Pakistan Institute of Engineering and Applied Sciences (External organisation)

Thomas Vorup-Jensen (Member)

29 Jan 2023

Journal of Immunology (Journal)

Thomas Vorup-Jensen (Editor)

5 Jan 2023

Press clippings

Zebrafisk kan hjælpe med at lappe ødelagte menneskehjerter

Thomas Vorup-Jensen

31/01/2023

1 Media contribution

Her er vores måske bedste coronavåben - næsevaccinen

Thomas Vorup-Jensen

10/05/2022

1 Media contribution

Ny teknologi kan bestemme sværhedsgraden af autoimmun sygdom

Kristian Juul-Madsen & Thomas Vorup-Jensen

17/11/2021

1 item of Media coverage

New Diagnostic Technique Measures Nanoparticles Linked To Lupus

Kristian Juul-Madsen & Thomas Vorup-Jensen

05/11/2021

1 item of Media coverage

Ny teknik identificerer sygdomsfremkaldende partikler i blodet

Thomas Vorup-Jensen & Kristian Juul-Madsen

17/10/2021

2 Media contributions

Peer-reviewed Publications

Ferapontov, A, Omer, M, Baudrexel, I, Nielsen, JS, Dupont, DM, Juul-Madsen, K, Steen, P, Eklund, AS, Thiel, S, Vorup-Jensen, T, Jungmann, R, Kjems, J & Degn, SE 2023, 'Antigen footprint governs activation of the B cell receptor', Nature Communications, vol. 14, no. 1, 976. https://doi.org/10.1038/s41467-023-36672-0
Voss, LF, Howarth, AJ, Wittenborn, TR, Hummelgaard, S, Juul-Madsen, K, Kastberg, KS, Pedersen, MK, Jensen, L, Papanastasiou, AD, Vorup-Jensen, T, Weyer, K & Degn, SE 2022, 'The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus', Frontiers in Immunology, vol. 13, 1021370. https://doi.org/10.3389/fimmu.2022.1021370
Jensen, RK, Pedersen, H, Lorentzen, J, Laursen, NS, Vorup-Jensen, T & Andersen, GR 2022, 'Structural insights into the function-modulating effects of nanobody binding to the integrin receptor αMβ2', Journal of Biological Chemistry, vol. 298, no. 8, 102168. https://doi.org/10.1016/j.jbc.2022.102168
Murphy, RA, Coates, M, Thrane, S, Sabnis, A, Harrison, J, Schelenz, S, Edwards, AM, Vorup-Jensen, T & Davies, JC 2022, 'Synergistic Activity of Repurposed Peptide Drug Glatiramer Acetate with Tobramycin against Cystic Fibrosis Pseudomonas aeruginosa', Microbiology spectrum, vol. 10, no. 4, e00813-22. https://doi.org/10.1128/spectrum.00813-22
Nielsen, MA, Juul-Madsen, K, Stegmayr, J, Gao, C, Mehta, AY, Greisen, SR, Kragstrup, TW, Hvid, M, Vorup-Jensen, T, Cummings, RD, Leffler, H & Deleuran, BW 2022, 'Galectin-3 Decreases 4-1BBL Bioactivity by Crosslinking Soluble and Membrane Expressed 4-1BB', Frontiers in Immunology, vol. 13, 915890. https://doi.org/10.3389/fimmu.2022.915890