Thomas Reinert

  1. 2020
  2. E-pub ahead of print

    Age-stratified reference intervals unlock the clinical potential of circulating cell-free DNA as a biomarker of poor outcome for healthy individuals and patients with colorectal cancer. / Ørntoft, Mai-Britt Worm; Jensen, Sarah Østrup; Øgaard, Nadia; Henriksen, Tenna Vesterman; Ferm, Linnea; Christensen, Ib Jarle; Reinert, Thomas; Larsen, Ole Halfdan; Nielsen, Hans Jørgen; Andersen, Claus Lindbjerg.

    In: International Journal of Cancer, 15.12.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    The effect of surgical trauma on circulating free DNA levels in cancer patients - implications for studies of circulating tumor DNA. / Henriksen, Tenna V; Reinert, Thomas; Christensen, Emil; Sethi, Himanshu; Birkenkamp-Demtröder, Karin; Gögenur, Mikail; Gögenur, Ismail; Zimmermann, Bernhard G; IMPROVE study group ; Dyrskjøt, Lars; Andersen, Claus L.

    In: Molecular Oncology, Vol. 14, No. 8, 2020, p. 1670-1679.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. 2019
  5. Published

    Analysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal Cancer. / Reinert, Thomas.

    2019. 1 Poster session presented at 3rd Annual Research Meeting 2019, Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearch

  6. Published

    Analysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal Cancer. / Reinert, Thomas.

    2019. Poster session presented at Danske Kræftforskningsdage. , Odense, Denmark.

    Research output: Contribution to conferencePosterResearch

  7. Published

    Analysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal Cancer. / Reinert, Thomas; Henriksen, Tenna Vesterman; Christensen, Emil; Sharma, Shruti; Salari, Raheleh; Sethi, Himanshu; Knudsen, Michael; Nordentoft, Iver; Wu, Hsin-Ta; Tin, Antony S; Heilskov Rasmussen, Mads; Vang, Søren; Shchegrova, Svetlana; Frydendahl Boll Johansen, Amanda; Srinivasan, Ramya; Assaf, Zoe; Balcioglu, Mustafa; Olson, Alexander; Dashner, Scott; Hafez, Dina; Navarro, Samantha; Goel, Shruti; Rabinowitz, Matthew; Billings, Paul; Sigurjonsson, Styrmir; Dyrskjøt, Lars; Swenerton, Ryan; Aleshin, Alexey; Laurberg, Søren; Husted Madsen, Anders; Kannerup, Anne-Sofie; Stribolt, Katrine; Palmelund Krag, Søren; Iversen, Lene H; Gotschalck Sunesen, Kåre; Lin, Cheng-Ho Jimmy; Zimmermann, Bernhard G; Lindbjerg Andersen, Claus.

    In: JAMA Oncology, Vol. 5, No. 8, 01.08.2019, p. 1124-1131.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Early Detection of Metastatic Relapse and Monitoring of Therapeutic Efficacy by Ultra-Deep Sequencing of Plasma Cell-Free DNA in Patients With Urothelial Bladder Carcinoma. / Christensen, Emil; Birkenkamp-Demtröder, Karin; Sethi, Himanshu; Shchegrova, Svetlana; Salari, Raheleh; Nordentoft, Iver; Wu, Hsin-Ta; Knudsen, Michael; Lamy, Philippe; Lindskrog, Sia Viborg; Taber, Ann; Balcioglu, Mustafa; Vang, Søren; Assaf, Zoe; Sharma, Shruti; Tin, Antony S; Srinivasan, Ramya; Hafez, Dina; Reinert, Thomas; Navarro, Samantha; Olson, Alexander; Ram, Rosalyn; Dashner, Scott; Rabinowitz, Matthew; Billings, Paul; Sigurjonsson, Styrmir; Andersen, Claus Lindbjerg; Swenerton, Ryan; Aleshin, Alexey; Zimmermann, Bernhard; Agerbæk, Mads; Lin, Cheng-Ho Jimmy; Jensen, Jørgen Bjerggaard; Dyrskjøt, Lars.

    In: Journal of Clinical Oncology, Vol. 37, No. 18, 06.2019, p. 1547-1557.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Longitudinal analysis of plasma cell-free DNA by ultra-deep sequencing in stage I-III colorectal cancer patients: a prospective observational study. / Reinert, Thomas.

    2019. Poster session presented at 4th International Meeting on Cell-Free DNA, København, Denmark.

    Research output: Contribution to conferencePosterResearch

  10. 2018
  11. Published

    Serial circulating tumor DNA analysis for detection of residual disease, assessment of adjuvant therapy efficacy and for early recurrence detection in colorectal cancer. / Reinert, Thomas.

    2018. Poster session presented at ESMO 2018 Congress, München, Germany.

    Research output: Contribution to conferencePosterResearch

  12. 2017
  13. Published

    Clinical implications of monitoring circulating tumor DNA in patients with colorectal cancer. / Reinert, Thomas.

    2017. Poster session presented at 1st Annual Research Meeting, Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearch

  14. Published

    Clinical implications of monitoring circulating tumor DNA in patients with colorectal cancer. / Reinert, Thomas.

    2017. Poster session presented at 10th International Symposium on Circulating Nucleic Acids in Plasma and Serum., Montpellier, France.

    Research output: Contribution to conferencePosterResearch

  15. Published

    Clinical implications of monitoring circulating tumor DNA in patients with colorectal cancer. / Schøler, Lone V; Reinert, Thomas; Ørntoft, Mai-Britt W; Kassentoft, Christine Gaasdal; Árnadóttir, Sigrid S; Vang, Søren; Nordentoft, Iver; Knudsen, Michael; Lamy, Philippe; Andreasen, Ditte; Mortensen, Frank V; Knudsen, Anders Riegels; Stribolt, Katrine; Sivesgaard, Kim; Mouritzen, Peter; Nielsen, Hans Jørgen; Laurberg, Søren; Ørntoft, Torben F; Andersen, Claus L.

    In: Clinical Cancer Research, Vol. 23, No. 18, 09.2017, p. 5437-5445.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Prognostic Impact of a 12-gene Progression Score in Non-muscle-invasive Bladder Cancer : A Prospective Multicentre Validation Study. / Dyrskjøt, Lars; Reinert, Thomas; Algaba, Ferran; Christensen, Emil; Nieboer, Daan; Hermann, Gregers G; Mogensen, Karin; Beukers, Willemien; Marquez, Mirari; Segersten, Ulrika; Høyer, Søren; Ulhøi, Benedicte P; Hartmann, Arndt; Stöhr, Robert; Wach, Sven; Nawroth, Roman; Schwamborn, Kristina; Tulic, Cane; Simic, Tatjana; Junker, Kerstin; Harving, Niels; Petersen, Astrid C; Jensen, Jørgen B; Keck, Bastian; Grimm, Marc-Oliver; Horstmann, Marcus; Maurer, Tobias; Steyerberg, Ewout W; Zwarthoff, Ellen C; Real, Francisco X; Malats, Núria; Malmström, Per-Uno; Ørntoft, Torben F.

    In: European Urology, Vol. 72, No. 3, 09.2017, p. 461-469.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Direct detection of early-stage cancers using circulating tumor DNA. / Phallen, Jillian; Sausen, Mark; Adleff, Vilmos; Leal, Alessandro; Hruban, Carolyn; White, James; Anagnostou, Valsamo; Fiksel, Jacob; Cristiano, Stephen; Papp, Eniko; Speir, Savannah; Reinert, Thomas; Orntoft, Mai-Britt Worm; Woodward, Brian D; Murphy, Derek; Parpart-Li, Sonya; Riley, David; Nesselbush, Monica; Sengamalay, Naomi; Georgiadis, Andrew; Li, Qing Kay; Madsen, Mogens Rørbæk; Mortensen, Frank Viborg; Huiskens, Joost; Punt, Cornelis; van Grieken, Nicole; Fijneman, Remond; Meijer, Gerrit; Husain, Hatim; Scharpf, Robert B; Diaz, Luis A; Jones, Siân; Angiuoli, Sam; Ørntoft, Torben; Nielsen, Hans Jørgen; Andersen, Claus Lindbjerg; Velculescu, Victor E.

    In: Science Translational Medicine, Vol. 9, No. 403, 16.08.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. 2016
  19. Published

    Comprehensive Transcriptional Analysis of Early-Stage Urothelial Carcinoma. / Hedegaard, Jakob; Lamy, Philippe; Nordentoft, Iver; Algaba, Ferran; Høyer, Søren; Ulhøi, Benedicte Parm; Vang, Søren; Reinert, Thomas; Hermann, Gregers G; Mogensen, Karin; Thomsen, Mathilde Borg Houlberg; Nielsen, Morten Muhlig; Marquez, Mirari; Segersten, Ulrika; Aine, Mattias; Höglund, Mattias; Birkenkamp-Demtröder, Karin; Fristrup, Niels; Borre, Michael; Hartmann, Arndt; Stöhr, Robert; Wach, Sven; Keck, Bastian; Seitz, Anna Katharina; Nawroth, Roman; Maurer, Tobias; Tulic, Cane; Simic, Tatjana; Junker, Kerstin; Horstmann, Marcus; Harving, Niels; Petersen, Astrid Christine; Calle, M Luz; Steyerberg, Ewout W; Beukers, Willemien; van Kessel, Kim E M; Jensen, Jørgen Bjerggaard; Pedersen, Jakob Skou; Malmström, Per-Uno; Malats, Núria; Real, Francisco X; Zwarthoff, Ellen C; Ørntoft, Torben Falck; Dyrskjøt, Lars.

    In: Cancer Cell, Vol. 30, No. 1, 11.07.2016, p. 27–42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Genomic Alterations in Liquid Biopsies from Patients with Bladder Cancer. / Birkenkamp-Demtröder, Karin; Nordentoft, Iver Kristiansen; Christensen, Emil; Høyer, Søren; Reinert, Thomas; Vang, Søren; Borre, Michael; Agerbæk, Mads; Jensen, Jørgen Bjerggaard; Ørntoft, Torben Falck; Dyrskjøt, Lars .

    In: European Urology, 21.01.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Analysis of circulating tumour DNA to monitor disease burden following colorectal cancer surgery. / Reinert, Thomas; Schøler, Lone Vedel; Thomsen, Rune; Tobiasen, Heidi; Vang, Søren; Nordentoft, Iver Kristiansen; Lamy, Philippe; Kannerup, Anne-Sofie; Mortensen, Frank Viborg; Stribolt, Katrine; Hamilton-Dutoit, Stephen Jacques; Laurberg, Søren; Pallisgaard, N.; Pedersen, Jakob Skou; Ørntoft, Torben Falck; Andersen, Claus Lindbjerg.

    In: Gut, Vol. 65, No. 4, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. 2015
  23. Published
  24. 2014
  25. Published

    Mutational context and diverse clonal development in early and late bladder cancer : Genomic changes in bladder cancer. / Nordentoft, Iver Kristiansen; Lamy, Philippe; Birkenkamp-Demtröder, Karin; Shumansky, Karey ; Vang, Søren; Hornshøj, Henrik; Juul, Malene ; Villesen, Palle; Hedegaard, Jakob; Roth, Andrew; Thorsen, Kasper; Høyer, Søren; Borre, Michael; Reinert, Thomas; Fristrup, Niels; Dyrskjøt, Lars; Shah, Sohrab; Pedersen, Jakob Skou; Ørntoft, Torben Falck.

    In: Cell Reports, Vol. 7, No. 5, 12.06.2014, p. 1649–1663.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Genome and RNA sequencing identifies fusion transcripts in bladder cancer. / Nordentoft, Iver Kristiansen; Birkenkamp-Demtröder, Karin; Lamy, Philippe; Reinert, Thomas; Vang, Søren; Hedegaard, Jakob; Thorsen, Kasper; Dyrskjøt, Lars; Pedersen, Jakob Skou; Ørntoft, Torben Falck.

    2014. Abstract from AACR Annual Meeting 2014, San Diego, California, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  27. 2013
  28. Published
  29. Published

    Multicenter validation of Cyclin D1, MCM7, TRIM29, and UBE2C as prognostic protein markers in non-muscle invasive bladder cancer. / Fristrup, Niels; Birkenkamp-Demtröder, Karin; Reinert, Thomas; Sanchez-Carbayo, Marta; Segersten, Ulrika; Malmström, Per-Uno ; Palou, Joan ; Alvarez-Múgica, Miguel ; Pan, Chin-Chen ; Ulhøi, Benedicte Parm; Borre, Michael; Ørntoft, Torben Falck; Andersen, Lars Dyrskjøt.

    In: American Journal of Pathology, Vol. 182, No. 2, 02.2013, p. 339-349.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. 2012
  31. Published

    Analysis of molecular intra-patient variation and delineation of a prognostic 12-gene signature in non-muscle invasive bladder cancer; technology transfer from microarrays to PCR. / Andersen, Lars Dyrskjøt; Reinert, Thomas; Novoradovsky, A; Zuiverloon, T C M; Beukers, W; Zwarthoff, E; Malats, N; Real, F X; Segersten, U; Malmström, P-U; Knowles, M; Hurst, C; Sorge, J; Borre, M; Orntoft, T F.

    In: B J C, No. 107, 13.09.2012, p. 1392-1398.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Methylation markers for urine-based detection of bladder cancer: the next generation of urinary markers for diagnosis and surveillance of bladder cancer. / Reinert, Thomas.

    In: Advances in Urology, Vol. 2012, 04.2012, p. 1-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    A high resolution genomic portrait of bladder cancer : correlation between genomic aberrations and the DNA damage response. / Schepeler, T; Lamy, P; Laurberg, J R; Fristrup, N; Reinert, Thomas; Bartkova, J; Tropia, L; Bartek, Jiri; Halazonetis, T D; Pan, C-C; Borre, M; Andersen, Lars Dyrskjøt; Orntoft, T F.

    In: Oncogene, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Combinations of urinary biomarkers for surveillance of patients with incident non-muscle invasive bladder cancer: The European FP7 UROMOL Project. / Zuiverloon, Tahlita C M; Beukers, Willemien; van der Keur, Kirstin A; Nieuweboer, Annemieke J M; Reinert, Thomas; Dyrskjot, Lars; Orntoft, Torben F; Zwarthoff, Ellen C.

    In: Journal of Urology, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published
  36. Published

    Diagnosis of Bladder Cancer Recurrence Based on Urinary Levels of EOMES, HOXA9, POU4F2, TWIST1, VIM, and ZNF154 Hypermethylation. / Reinert, Thomas; Borre, Michael; Christiansen, Anders; Hermann, Gregers; Orntoft, Torben F; Andersen, Lars Dyrskjøt.

    In: P L o S One, Vol. 7, No. 10, 2012, p. e46297.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Expression of MAGE-A3, NY-ESO-1, LAGE-1 and PRAME in urothelial carcinoma. / Andersen, Lars Dyrskjøt; Zieger, K; Kissow Lildal, T; Reinert, Thomas; Gruselle, O; Coche, T; Borre, M; Ørntoft, T F.

    In: B J C, Vol. 107, No. 1, 2012, p. 116-22.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. 2011
  39. Published

    Comprehensive genome methylation analysis in bladder cancer;identification and validation of novel methylated genes and application of these as urinary tumor markers. / Reinert, Thomas; Modin, Charlotte; Mansilla Castano, Francisco; Lamy, Philippe; Wojdacz, Tomasz K; Hansen, Lise Lotte; Wiuf, Carsten; Borre, Michael; Andersen, Lars Dyrskjøt; Ørntoft, Torben Falck.

    In: Clinical Cancer Research, 25.07.2011.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. 2008
  41. Published

    Diagnostic and prognostic microRNAs in stage II colon cancer. / Schepeler, Troels; Reinert, Thomas; Ostenfeld, Marie S; Christensen, Lise L; Silahtaroglu, Asli N; Dyrskjøt, Lars; Wiuf, Carsten; Sørensen, Frank J; Kruhøffer, Mogens; Laurberg, Søren; Kauppinen, Sakari; Ørntoft, Torben F; Andersen, Claus L.

    In: Cancer Research, Vol. 68, No. 15, 2008, p. 6416-24.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response. / Paun, Andrea; Reinert, Thomas; Jiang, Zhaozhao; Medin, Carey; Balkhi, Mumtaz Yaseen; Fitzgerald, Katherine A; Pitha, Paula M.

    In: Journal of Biological Chemistry, Vol. 283, No. 21, 2008, p. 14295-308.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. 2006
  44. Published

    ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation. / Lu, G; Reinert, Thomas; Pitha-Rowe, I; Okumura, A; Kellum, M; Knobeloch, K P; Hassel, B; Pitha, P M; Reinert, Thomas.

    In: Cellular and Molecular Biology, Vol. 52, No. 1, 2006, p. 29-41.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review