Thomas Holm Pedersen

  1. 2021
  2. Published

    Myopathic changes in patients with long-term fatigue after COVID-19. / Agergaard, J.; Leth, S.; Pedersen, T. H.; Harbo, T.; Blicher, J. U.; Karlsson, P.; Andersen, H.; Tankisi, H.

    In: Clinical Neurophysiology, Vol. 132, No. 8, 08.2021, p. 1974-1981.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Quantitative model analysis of the resting membrane potential in insect skeletal muscle : Implications for low temperature tolerance. / Bayley, Jeppe Seamus; Overgaard, Johannes; Pedersen, Thomas Holm.

    In: Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology, Vol. 257, 110970, 07.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Early detection of evolving critical illness myopathy with muscle velocity recovery cycles. / Tankisi, A.; Pedersen, T. H.; Bostock, H.; Z'Graggen, W. J.; Larsen, L. H.; Meldgaard, M.; Elkmann, T.; Tankisi, H.

    In: Clinical Neurophysiology, Vol. 132, No. 6, 06.2021, p. 1347-1357.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Accepted/In press

    Reply to “Maybe myopathic EMG but not myopathy” and to “Exclude differentials before attributing post-COVID fatigue to myopathy”. / Agergaard, J.; Leth, S.; Pedersen, T. H.; Harbo, T.; Blicher, J. U.; Karlsson, P.; Østergaard, L.; Andersen, H.; Tankisi, H.

    In: Clinical Neurophysiology, 2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperLetterResearchpeer-review

  6. 2020
  7. Published

    Critical illness myopathy as a consequence of Covid-19 infection. / Tankisi, H.; Tankisi, A.; Harbo, T.; Markvardsen, L. K.; Andersen, H.; Pedersen, T. H.

    In: Clinical Neurophysiology, Vol. 131, No. 8, 08.2020, p. 1931-1932.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperComment/debate/letter to the editorResearchpeer-review

  8. Published

    Depletion of ATP Limits Membrane Excitability of Skeletal Muscle by Increasing Both ClC1-Open Probability and Membrane Conductance. / Leermakers, Pieter Arnold; Dybdahl, Kamilla Løhde Tordrup; Husted, Kristian Søborg; Riisager, Anders; de Paoli, Frank Vincenzo; Pinós, Tomàs ; Vissing, John ; Krag, Thomas ; Pedersen, Thomas Holm.

    In: Frontiers in Neurology, Vol. 11, 541, 2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. 2019
  10. Published

    Muscle velocity recovery cycles in neurogenic muscles. / Witt, Agnes Hauschultz; Søgaard Kristensen, Rikke; Fuglsang-Frederiksen, Anders; Pedersen, Thomas Holm; Finnerup, Nanna Brix; Kasch, Helge; Tankisi, Hatice.

    In: Clinical Neurophysiology, Vol. 130, No. 9, 09.2019, p. 1520-1527.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Fatiguing stimulation increases curvature of the force-velocity relationship in isolated fast-twitch and slow-twitch rat muscles. / Kristensen, Anders M.; Nielsen, Ole B.; Pedersen, Thomas H.; Overgaard, Kristian.

    In: The Journal of Experimental Biology, Vol. 222, No. 15, jeb204545 , 08.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    O-26 Muscle velocity recovery cycles in neurogenic muscles. / Witt, Agnes Hauschultz; Søgaard Kristensen, Rikke; Fuglsang-Frederiksen, Anders; Pedersen, Thomas Holm; Finnerup, Nanna Brix; Kasch, Helge; Tankisi, Hatice.

    In: Clinical Neurophysiology, Vol. 130, No. 7, 01.07.2019, p. e30.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearchpeer-review

  13. Published

    Cold acclimation modulates voltage gated Ca 2+ channel currents and fiber excitability in skeletal muscles of Locusta migratoria. / Bayley, Jeppe Seamus; Klepke, Martin Johannesen; Pedersen, Thomas Holm; Overgaard, Johannes.

    In: Journal of Insect Physiology, Vol. 114, 2019, p. 116-124.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. 2018
  15. Published

    Cold exposure causes cell death by depolarization-mediated Ca2+ overload in a chill-susceptible insect. / Bayley, Jeppe Seamus; Winther, Christian Bak; Andersen, Mads Kuhlmann; Grønkjær, Camilla; Nielsen, Ole Bækgaard; Pedersen, Thomas Holm; Overgaard, Johannes.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 41, 2018, p. E9737-E9744.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. 2017
  17. Published

    Chloride Channels Take Center Stage in Acute Regulation of Excitability in Skeletal Muscle : Implications for Fatigue. / Bækgaard Nielsen, Ole; de Paoli, Frank Vincenzo; Riisager, Anders; Pedersen, Thomas Holm.

    In: Physiology, Vol. 32, No. 6, 11.2017, p. 425-434.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  18. Published

    The anti-convulsants lacosamide, lamotrigine and rufinamide reduce myotonia in isolated human and rat skeletal muscle. / Skov, Martin; de Paoli, Frank V; Nielsen, Ole B; Pedersen, Thomas H.

    In: Muscle & Nerve, Vol. 56, No. 1, 07.2017, p. 136-142.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. 2016
  20. Published

    Skeletal muscle dysfunction in the db/db mouse model of type 2 diabetes. / Bayley, Jeppe Seamus; Pedersen, Thomas Holm; Nielsen, Ole Baekgaard.

    In: Muscle & Nerve, Vol. 54, No. 3, 09.2016, p. 460-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Reduced L-type Ca2+ current and compromised excitability induce loss of skeletal muscle function during acute cooling in locust. / Findsen, Anders; Overgaard, Johannes; Pedersen, Thomas Holm.

    In: The Journal of Experimental Biology, Vol. 219, No. Pt 15, 01.08.2016, p. 2340-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Protein kinase C dependent regulation of ClC-1 channels in active human muscle and its effect on fast and slow gating. / Riisager, Anders; de Paoli, Frank Vincenzo; Yu, Wei-Ping; Pedersen, Thomas Holm; Chen, Tsung-Yu; Nielsen, Ole Bækgaard.

    In: The Journal of Physiology, 15.06.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Role of physiological ClC-1 Cl- ion channel regulation for the excitability and function of working skeletal muscle. / Pedersen, Thomas Holm; Riisager, Anders; de Paoli, Frank Vincenzo; Chen, Tsung-Yu; Nielsen, Ole Bækgaard.

    In: Journal of General Physiology, Vol. 147, No. 4, 28.03.2016, p. 291-308 .

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. 2015
  25. Published

    Divalent cation-responsive myotonia and muscle paralysis in skeletal muscle sodium channelopathy. / Mankodi, Ami; Grunseich, Christopher; Skov, Martin; Cook, Lisa; Aue, Georg; Purev, Enkhtsetseg; Bakar, Dara; Lehky, Tanya; Jurkat-Rott, Karin; Pedersen, Thomas H; Childs, Richard W.

    In: Neuromuscular Disorders, Vol. 25, No. 11, 11.2015, p. 908-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Extracellular magnesium and calcium reduce myotonia in isolated ClC-1 chloride channel-inhibited human muscle. / Skov, Martin; De Paoli, Frank Vincenzo; Lausten, Jesper; Nielsen, Ole Baekgaard; Pedersen, Thomas Holm.

    In: Muscle & Nerve, Vol. 51, No. 1, 01.2015, p. 65-71.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. 2014
  28. Published

    Determination of cable parameters in skeletal muscle fibres during repetitive firing of action potentials. / Riisager, Anders; Duehmke, Rudy; Nielsen, Ole Bækgaard; Huang, Christopher L; Pedersen, Thomas Holm.

    In: The Journal of Physiology, Vol. 592, No. 20, 15.10.2014, p. 4417-4429.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    Thermal sensitivity of excitation-contraction-coupling in a chill susceptible insect, Locusta migratoria. / Findsen, Anders; Pedersen, Thomas Holm; Overgaard, Johannes.

    2014. Poster session presented at 2014 APS Intersociety Meeting: Comparative Approaches to Grand Challenges in Physiology , San Diego, United States.

    Research output: Contribution to conferencePosterResearch

  30. Published

    Cold-induced depolarization of insect muscle : differing roles of extracellular K+ during acute and chronic chilling. / MacMillan, Heath Andrew; Findsen, Anders; Pedersen, Thomas Holm; Overgaard, Johannes.

    In: Journal of Experimental Biology, Vol. 217, No. 16, 08.2014, p. 2930-2938.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    Why do insects enter and recover from chill coma? Low temperature and high extracellular potassium compromises muscle function in Locusta migratoria. / Findsen, Anders; Pedersen, Thomas Holm; Petersen, Asbjørn G; Nielsen, Ole Bækgaard; Overgaard, Johannes.

    In: Journal of Experimental Biology, Vol. 217, No. 8, 2014, p. 1297-1306.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. 2013
  33. Published

    Neuro-muscular function in the wobbler murine model of primary motor neuronopathy. / Broch-Lips, Martin; Pedersen, Thomas Holm; Riisager, Anders; Schmitt-John, Thomas; Nielsen, Ole Bækgaard.

    In: Experimental Neurology, Vol. 248, 10.2013, p. 406-415.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Why do insects enter chill coma? Low temperature and high extracellular potassium compromises muscle function in Locusta migratoria. / Findsen, Anders; Pedersen, Thomas Holm; Nielsen, Ole Bækgaard; Overgaard, Johannes.

    2013. Abstract from Annual Main Meeting for the Society of Experimental Biologists 2013, Valencia, Spain.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  35. Published

    Extracellular magnesium and calcium reduce myotonia in ClC-1 inhibited rat muscle. / Skov, Martin; Riisager, Anders ; Fraser, James A; Nielsen, Ole B; Pedersen, Thomas H.

    In: Neuromuscular Disorders, Vol. 23, No. 6, 2013, p. 489-502.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Relationship between membrane Cl- conductance and contractile endurance in isolated rat muscles. / de Paoli, Frank Vincenzo; Broch-Lips, Martin; Pedersen, Thomas Holm; Nielsen, Ole Bækgaard.

    In: The Journal of Physiology, Vol. 591, No. 2, 2013, p. 531-545.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. 2012
  38. Published

    Altered re-excitation thresholds and conduction of extrasystolic action potentials contribute to arrhythmogenicity in murine models of long QT syndrome. / Duehmke , RM; Pearcey, S; Stefaniak, JD; Guzadhur , L; Jeevaratnam , K; Costopoulos , C; Pedersen, Thomas Holm; Grace , AA; Huang, CL.

    In: Acta Physiologica (Print), Vol. 206, No. 3, 11.2012, p. 164-177.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    Commentaries on viewpoint: maximal Na⁺-K⁺-ATPase activity is upregulated in association with muscle activity. / Broch-Lips, Martin; Pedersen, Thomas Holm; Nielsen, Ole Bækgaard.

    In: Journal of Applied Physiology, Vol. 112, No. 12, 06.2012, p. 2124-2126.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    Chloride distribution in muscle – a way for the Na+-K+ pump to buy more time for the recovery of K+ gradients during exercise. / Nielsen, Ole Bækgaard; Pedersen, Thomas Holm; de Paoli, Frank Vincenzo; Broch-Lips, Martin.

    In: Journal of Applied Physiology, Vol. 112, No. 12, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  41. Published

    Na+-K+ pump activity in active muscles – a need for detail. / Broch-Lips, Martin; de Paoli, Frank Vincenzo; Pedersen, Thomas Holm; Nielsen, Ole Bækgaard.

    In: Journal of Applied Physiology, Vol. 112, No. 12, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. 2011
  43. Published

    An analysis of the relationships between sub-threshold electrical properties and excitability in skeletal muscle. / Pedersen, Thomas Holm; Huang, Christopher L.; Fraser, James A. .

    In: Journal of General Physiology, Vol. 138(1), 2011, p. 73-93.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    Effects of 8 wks of free-wheel running on K+-tolerance and excitability of soleus muscles in rat. / Broch-Lips, Martin; Paoli, Frank de; Pedersen, Thomas Holm; Overgaard, Kristian; Nielsen, Ole Bækgaard.

    In: Journal of Applied Physiology, Vol. 111(1), 2011, p. 212-220.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    Na+,K+-pump stimulation improves contractility in isolated muscles of mice with hyperkalemic periodic paralysis. / Clausen, Torben; Nielsen, Ole Bækgaard; Clausen, Johannes D.; Pedersen, Thomas Holm; Hayward, Lawrence J.

    In: Journal of General Physiology, Vol. 138, 2011, p. 117-130.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    Reciprocal dihydropyridine and ryanodine receptor interactions in skeletal muscle activation. / Huang, Christopher L. ; Pedersen, Thomas Holm; Fraser, James A. .

    In: Journal of Muscle Research and Cell Motility, Vol. 32(3), 2011, p. 171-202.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    Relationships between resting conductances, excitability and t-system ionic homeostasis in skeletal muscle. / Fraser, James A.; Huang, Christopher L. ; Pedersen, Thomas Holm.

    In: Journal of General Physiology, Vol. 138(1) , 2011, p. 95-116.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  48. 2010
  49. Published

    Lactate per se improves the excitability of depolarized rat skeletal muscle by reducing the Cl- conductance. / de Paoli, Frank Vincenzo; Ørtenblad, Niels; Pedersen, Thomas Holm; Jørgensen, Rasmus; Nielsen, Ole Bækgaard.

    In: Journal of Physiology, Vol. 588, No. Pt 23, 01.12.2010, p. 4785-4794.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    Effect of purinergic receptor activation on Na+-K+ pump activity, excitability, and function in depolarized skeletal muscle. / Broch-Lips, Martin; Pedersen, Thomas Holm; Nielsen, Ole Bækgaard.

    In: American Journal of Physiology (Consolidated), Vol. 298, No. 6, 01.06.2010, p. C1438-C1444.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. 2009
  52. Published

    Calmodulin kinase II initiates arrhythmogenicity during metabolic acidification in murine hearts. / Pedersen, Thomas Holm; Gurung, Iman S.; Grace, Andrew; Huang, Christopher L.

    In: Acta Physiologica (Print), Vol. 197, 2009, p. 13-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Comparison of regulated passive membrane conductance in action potential-firing fast- and slow-twitch muscle. / Pedersen, Thomas Holm; Macdonald, William; de Paoli, Frank Vincenzo; Nielsen, Ole Bækgaard.

    In: Journal of General Physiology, Vol. 134, No. 4, 2009.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  54. Published

    Comparison of regulated passive membrane conductance in action potential-firing fast- and slow-twitch muscle. / Pedersen, Thomas Holm; Macdonald, William A.; de Paoli, Frank; Gurung, Iman S.; Nielsen, Ole Bækgaard.

    In: Journal of General Physiology, Vol. 134, 2009, p. 323-337.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  55. Published

    Regulation of ClC-1 and KATP channels in action potential-firing fast-twitch muscle fibers. / Pedersen, Thomas Holm; de Paoli, Frank; Flatman, John A.; Nielsen, Ole Bækgaard.

    In: Journal of General Physiology, Vol. 134, 2009, p. 309-322.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  56. Published

    Regulation of ClC-1 and KATP channelsin action potential-firing fast-twitch muscle fibres. / Pedersen, Thomas Holm; de Paoli, Frank Vincenzo; Flatman, John A.; Nielsen, Ole Bækgaard.

    In: Journal of General Physiology, Vol. 134, No. 4, 2009.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. 2008
  58. Published

    Scn3b knockout mice exhibit abnormal ventricular electrophysiological properties. / Hakim, Parvez; Gurung, Iman S.; Pedersen, Thomas Holm; Thresher, R; Brice, N; Lawrence, J; Grace, Andrew A.; Huang, Christopher L.

    In: Progress in Biophysics & Molecular Biology, Vol. 98, 2008, p. 251-266.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  59. 2007
  60. Published

    Additive protective effects of the addition of lactic acid and adrenaline on excitability and force in isolated rat skeletal muscle depressed by elevated extracellular K+. / de Paoli, Frank Vincenzo; Overgaard, Kristian; Pedersen, Thomas Holm; Nielsen, Ole Bækgaard.

    In: Journal of Physiology, Vol. 581, 2007.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  61. Published

    Additive protective effects of the addition of lactic acid and adrenaline on excitability and force in isolated rat skeletal muscle depressed by elevated extracellular K+. / Paoli, Frank de; Overgaard, Kristian; Pedersen, Thomas Holm; Nielsen, Ole Bækgaard.

    In: Journal of Physiology, Vol. 581, No. 2, 2007, p. 829-839.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  62. 2005
  63. Published

    Increased excitability of acidified skeletal muscle: Role of chloride conductance. / Pedersen, Thomas Holm; de Paoli, Frank Vincenzo; Nielsen, Ole Bækgaard.

    In: Journal of General Physiology, Vol. 125, 2005.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  64. Published

    Increased excitability of acidified skeletal muscle: role of chloride conductance. / Pedersen, Thomas Holm; Paoli, Frank de; Nielsen, Ole Bækgaard.

    In: J. Gen. Physiol., Vol. 125, 2005, p. 237-246.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  65. Published

    N-Benzyl-p-toluene sulphonamide allows the recording of trains of intracellu­lar action potentials from nerve stimulated intact fast-twitch skeletal muscle of the rat. / MacDonald, William; Pedersen, Thomas Holm; Clausen, Torben; Nielsen, Ole Bækgaard.

    In: Experimental Physiology, Vol. 90, 2005, p. 815-825.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  66. 2004
  67. Published

    Intracellular acidosis enhances the excitability of working muscle. / Pedersen, T.H.; Nielsen, O.B.; Lamb, G.D.; Stephenson, D.G.

    In: Science, Vol. 305, 2004, p. 1141-1144.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  68. 2003
  69. Published

    Loss of force induced by high extracellular K+ in rat muscle - effect of temperature, lactic acid and β2 agonist. / Pedersen, T.H.; Clausen, T.; Nielsen, O.B.

    In: Journal of Physiology, Vol. 551, 2003, p. 277-286.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review