Research output per year
Research output per year
- 14 results
Search results
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2024
Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment
Juul-Madsen, K., Parbo, P., Ismail, R., Ovesen, P. L., Schmidt, V., Madsen, L. S., Thyrsted, J., Gierl, S., Breum, M., Larsen, A., Andersen, M. N., Romero-Ramos, M., Holm, C. K., Andersen, G. R., Zhao, H., Schuck, P., Nygaard, J. V., Sutherland, D. S., Eskildsen, S. F. & Willnow, T. E. & 2 others, , Feb 2024, In: Nature Communications. 15, 1, 20 p., 1224.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting
Bolduan, F., Wetzel, A., Giesecke, Y., Eichhorn, I., Alenina, N., Bader, M., Willnow, T. E., Wiedenmann, B. & Sigal, M., 2024, In: Frontiers in Endocrinology. 15, 1331231.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
SORCS2 activity in pancreatic α-cells safeguards insulin granule formation and release from glucose-stressed β-cells
Kalnytska, O., Qvist, P., Kunz, S., Conrad, T., Willnow, T. E. & Schmidt, V., Jan 2024, In: iScience. 27, 1, p. 108725 108725.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
2023
Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames
Sandmann, C. L., Schulz, J. F., Ruiz-Orera, J., Kirchner, M., Ziehm, M., Adami, E., Marczenke, M., Christ, A., Liebe, N., Greiner, J., Schoenenberger, A., Muecke, M. B., Liang, N., Moritz, R. L., Sun, Z., Deutsch, E. W., Gotthardt, M., Mudge, J. M., Prensner, J. R. & Willnow, T. E. & 3 others, , Mar 2023, In: Molecular Cell. 83, 6, p. 994-1011.e18Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
2022
SORLA mediates endocytic uptake of proIAPP and protects against islet amyloid deposition
Shih, A. Z. L., Chen, Y. C., Speckmann, T., Søndergaard, E., Schürmann, A., Verchere, C. B. & Willnow, T. E., Nov 2022, In: Molecular Metabolism. 65, 101585.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
2021
ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling
Asaro, A., Sinha, R., Bakun, M., Kalnytska, O., Carlo-Spiewok, A. S., Rubel, T., Rozeboom, A., Dadlez, M., Kaminska, B., Aronica, E., Malik, A. R. & Willnow, T. E., Oct 2021, In: Journal of Cell Science. 134, 20, jcs258894.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile44 Downloads (Pure) -
GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium
Marczenke, M., Sunaga-Franze, D. Y., Popp, O., Althaus, I. W., Sauer, S., Mertins, P., Christ, A., Allen, B. L. & Willnow, T. E., Nov 2021, In: Development. 148, 21Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile29 Downloads (Pure) -
SORLA is required for insulin-induced expansion of the adipocyte precursor pool in visceral fat
Schmidt, V., Horváth, C., Dong, H., Blüher, M., Qvist, P., Wolfrum, C. & Willnow, T. E., Dec 2021, In: The Journal of Cell Biology. 220, 12, 21 p., e202006058.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile62 Downloads (Pure) -
2020
Apolipoprotein E4 disrupts the neuroprotective action of sortilin in neuronal lipid metabolism and endocannabinoid signaling
Asaro, A., Carlo-Spiewok, A.-S., Malik, A. R., Rothe, M., Schipke, C. G., Peters, O., Heeren, J. & Willnow, T. E., Sept 2020, In: Alzheimer's & dementia : the journal of the Alzheimer's Association. 16, 9, p. 1248-1258 11 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile35 Downloads (Pure) -
Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity
Seo, J. A., Kang, M.-C., Yang, W.-M., Hwang, W. M., Kim, S. S., Hong, S. H., Heo, J.-I., Vijyakumar, A., Pereira de Moura, L., Uner, A., Huang, H., Lee, S. H., Lima, I. S., Park, K. S., Kim, M. S., Dagon, Y., Willnow, T. E., Aroda, V., Ciaraldi, T. P. & Henry, R. R. & 1 others, , 24 Apr 2020, In: Nature Communications. 11, 1, p. 2024 2024.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly
Hong, M., Christ, A., Christa, A., Willnow, T. E. & Krauss, R. S., 2 Sept 2020, In: eLife. 9, p. 1-24 24 p., e60351.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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Induced pluripotent stem cell-based disease modeling identifies ligand-induced decay of megalin as a cause of Donnai-Barrow syndrome
Flemming, J., Marczenke, M., Rudolph, I. M., Nielsen, R., Storm, T., Christensen, E. I., Diecke, S., Emma, F. & Willnow, T. E., 2020, In: Kidney International. 98, 1, p. 159-167 9 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)35 Downloads (Pure) -
LRP2 controls sonic hedgehog-dependent differentiation of cardiac progenitor cells during outflow tract formation
Christ, A., Marczenke, M. & Willnow, T. E., Oct 2020, In: Human Molecular Genetics. 29, 19, p. 3183–3196 14 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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SorCS2 facilitates release of endostatin from astrocytes and controls post-stroke angiogenesis
Malik, A. R., Lips, J., Gorniak-Walas, M., Broekaart, D. W. M., Asaro, A., Kuffner, M. T. C., Hoffmann, C. J., Kikhia, M., Dopatka, M., Boehm-Sturm, P., Mueller, S., Dirnagl, U., Aronica, E., Harms, C. & Willnow, T. E., Jun 2020, In: Glia. 68, 6, p. 1304-1316 13 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review