Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Immunocompromised Host Displaying Treatment Induced Viral Evolution. / Monrad, Ida; Sahlertz, Signe Risgaard; Nielsen, Stine Sofie Frank et al.
In: Open Forum Infectious Diseases, Vol. 8, No. 7, ofab295, 07.2021.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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TY - JOUR
T1 - Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Immunocompromised Host Displaying Treatment Induced Viral Evolution
AU - Monrad, Ida
AU - Sahlertz, Signe Risgaard
AU - Nielsen, Stine Sofie Frank
AU - Pedersen, Louise Ørnskov
AU - Petersen, Mikkel Steen
AU - Kobel, Carl Mathias
AU - Tarpgaard, Irene Harder
AU - Storgaard, Merete
AU - Mortensen, Klaus Leth
AU - Schleimann, Mariane H.
AU - Tolstrup, Martin
AU - Vibholm, Line K.
N1 - Publisher Copyright: © 2021 The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
PY - 2021/7
Y1 - 2021/7
N2 - We report a coronavirus disease 2019 case with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) persisting beyond 333 days in an immunocompromised patient with chronic lymphocytic leukemia, asymptomatically carrying infectious SARS-CoV-2 at day 197 postdiagnosis. In addition, viral sequencing indicates major changes in the spike protein over time, temporally associated with convalescent plasma treatment.
AB - We report a coronavirus disease 2019 case with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) persisting beyond 333 days in an immunocompromised patient with chronic lymphocytic leukemia, asymptomatically carrying infectious SARS-CoV-2 at day 197 postdiagnosis. In addition, viral sequencing indicates major changes in the spike protein over time, temporally associated with convalescent plasma treatment.
KW - CLL
KW - persistent infection
KW - SARS-CoV-2
KW - viral evolution
UR - http://www.scopus.com/inward/record.url?scp=85112495039&partnerID=8YFLogxK
U2 - 10.1093/ofid/ofab295
DO - 10.1093/ofid/ofab295
M3 - Journal article
C2 - 34258320
AN - SCOPUS:85112495039
VL - 8
JO - Open Forum Infectious Diseases
JF - Open Forum Infectious Diseases
SN - 2328-8957
IS - 7
M1 - ofab295
ER -