Stine Mikkelsen

  1. 2019
  2. Published

    Phosphatidylserine flipping by the P4-ATPase ATP8A2 is electrogenic. / Tadini-Buoninsegni, Francesco; Mikkelsen, Stine A; Mogensen, Louise S; Molday, Robert S.; Andersen, Jens Peter.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 33, 13.08.2019, p. 16332-16337.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation. / Mikkelsen, Stine A; Mogensen, Louise S; Vilsen, Bente; Molday, Robert S; Vestergaard, Anna L; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, Vol. 294, No. 15, 04.2019, p. 5970-5979.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. 2018
  5. Published

    A Darier disease mutation relieves kinetic constraints imposed by the tail of sarco(endo)plasmic reticulum Ca2+-ATPase 2b. / Mikkelsen, Stine A; Vangheluwe, Peter; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, Vol. 293, 16.03.2018, p. 3880-3889.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. 2017
  7. Published
  8. Published
  9. Published

    Towards the structure of yeast and mammalian P4-ATPases : Poster at the 15th International Conference on Na,K-ATPase and Related Transport ATPases, Otsu, Japan, 2017. / Lyons, Joseph; Laban, Milena; Mikkelsen, Stine; Ulstrup, Jakob; Mogensen, Louise S; Montigny, Cédric; Ash, Miriam-Rose; Molday, Robert S.; Frauenfeld, Jens; Andersen, Jens Peter; Lenoir, Guillaume; Nissen, Poul.

    2017.

    Research output: Contribution to conferencePosterResearch

  10. Published

    Disease mutations reveal residues critical to the interaction of P4-ATPases with lipid substrates. / Gantzel, Rasmus H; Mogensen, Louise S; Mikkelsen, Stine A; Vilsen, Bente; Molday, Robert S; Vestergaard, Anna L; Andersen, Jens P.

    In: Scientific Reports, Vol. 7, No. 1, doi: 10.1038/s41598-017-10741-z., 05.09.2017, p. 10418.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. 2016
  12. Published

    Review: P4-ATPases as Phospholipid Flippases-Structure, Function, and Enigmas. / Andersen, Jens P; Vestergaard, Anna L; Mikkelsen, Stine A; Mogensen, Louise S; Chalat, Madhavan; Molday, Robert S.

    In: Frontiers in Physiology, Vol. 7, 2016, p. 275 (23 pages).

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. 2015
  14. Published

    Specific mutations in mammalian P4-ATPase ATP8A2 catalytic subunit entail differential glycosylation of the accessory CDC50A subunit. / Vestergaard, Anna L; Mikkelsen, Stine A; Coleman, Jonathan A; Molday, Robert S; Vilsen, Bente; Andersen, Jens Peter.

    In: FEBS Letters, Vol. 589, 22.11.2015, p. 3908-3914.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Biochemical characterization of P4-ATPase mutations associated with Intrahepatic Cholestatic Disease. / Gantzel, Rasmus; Vestergaard, Anna Lindeløv; Mikkelsen, Stine; Molday, Robert S.; Andersen, Jens Peter.

    2015. Abstract from Scandinavian Physiological Society Annual Meeting, Aarhus, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  16. Published

    Analysis of amino acid residues of potential importance for phosphatidylserine specificity of P4-type ATPase ARP8A2. / Mogensen, Louise; Vestergaard, Anna Lindeløv; Mikkelsen, Stine; Coleman, Jonathan Allan; Vilsen, Bente; Molday, Robert S.; Andersen, Jens Peter.

    2015. Poster session presented at 4th International Workshop on Expression, Structure and Function of Membrane Proteins, Firenze, Italy.

    Research output: Contribution to conferencePosterResearch

  17. Published

    Scanning mutagenesis of transmembrane segments M5 and M6 of the mammalian flippase ATP8A2 – evidence for a classic transport pathway? / Mikkelsen, Stine; Vestergaard, Anna Lindeløv; Coleman, Jonathan Allan; Vilsen, Bente; S. Molday, Robert; Andersen, Jens Peter.

    2015.

    Research output: Contribution to conferencePosterResearch

  18. Published

    Biochemical Characterization of P4-ATPase Mutations Associated with Intrahepatic Cholestatic Disease. / Gantzel, Rasmus; Vestergaard, Anna Lindeløv; Mikkelsen, Stine; S. Molday, Robert; Andersen, Jens Peter.

    2015. Poster session presented at 4th International Workshop on Expression, Structure and Function of Membrane Proteins, Firenze, Italy.

    Research output: Contribution to conferencePosterResearch

  19. 2014
  20. Published

    Analysis of Amino Acid Residues of Potential Importance for Phosphati-dylserine Specificity of P4-type ATPase ATP8A2. / Mogensen, Louise; Vestergaard, Anna Lindeløv; Mikkelsen, Stine; Coleman, Jonathan Allan; Vilsen, Bente; Molday, Robert S.; Andersen, Jens Peter.

    2014. Poster session presented at 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Netherlands.

    Research output: Contribution to conferencePosterResearch

  21. Published

    Darier disease mutation E917K of SERCA2b relieves the inhibitory influence of the 11th transmembrane segment. / Mikkelsen, Stine; Holdensen, Anne Nyholm; Vangheluwe, Peter; Vilsen, Bente; Andersen, Jens Peter.

    2014. Poster session presented at 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Netherlands.

    Research output: Contribution to conferencePosterResearch

  22. Published

    Stability cluster links hydrofobic gate to K873 in ATP8A2. / Mikkelsen, Stine; Vestergaard, Anna Lindeløv; Coleman, Jonathan Allan; Vilsen, Bente; Molday, Robert S.; Andersen, Jens Peter.

    2014. Poster session presented at 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Netherlands.

    Research output: Contribution to conferencePosterResearch

  23. Published

    Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2. / Vestergaard, Anna L; Coleman, Jonathan A; Lemmin, Thomas; Mikkelsen, Stine A; Molday, Laurie L; Vilsen, Bente; Molday, Robert S; Dal Peraro, Matteo; Andersen, Jens Peter.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 14, 08.04.2014, p. E1334-43.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Biochemical Characterization of P4-ATPase Mutations Associated with Intrahepatic Cholestatic Disease. / Gantzel, Rasmus; Vestergaard, Anna Lindeløv; Mikkelsen, Stine; Molday, Robert S.; Andersen, Jens Peter.

    2014. Poster session presented at Na,K-ATPase and related transport ATPases, structure, mechanism, cell biology, health and disease, Lunteren, Netherlands.

    Research output: Contribution to conferencePosterResearch

  25. 2012
  26. Published

    Functional impacts of the Darier Disease mutation E917K/E918K and addition of two different tails to SERCA. / Mikkelsen, Stine; Holdensen, Anne Nyholm; Vilsen, Bente; Andersen, Jens Peter.

    2012. Poster session presented at 3rd International Workshop on Expression, Structure and Function of Membrane Proteins , Florence, Italy.

    Research output: Contribution to conferencePosterResearch

  27. 2011
  28. Published