Stine Mikkelsen

Post doc

Profile photo

Stine Mikkelsen

Post doc

  • Department of Biomedicine - Forskning og uddannelse, Vest
Postal address:
Ole Worms Allé 3
8000
Aarhus C
Denmark

Email: smik@biomed.au.dk

Publications

Phosphatidylserine flipping by the P4-ATPase ATP8A2 is electrogenic

Tadini-Buoninsegni, F., Mikkelsen, S. A., Mogensen, L. S., Molday, R. S. & Andersen, J. P., 13 Aug 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 33, p. 16332-16337

Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation

Mikkelsen, S. A., Mogensen, L. S., Vilsen, B., Molday, R. S., Vestergaard, A. L. & Andersen, J. P., Apr 2019, In : Journal of Biological Chemistry. 294, 15, p. 5970-5979 10 p.

A Darier disease mutation relieves kinetic constraints imposed by the tail of sarco(endo)plasmic reticulum Ca2+-ATPase 2b

Mikkelsen, S. A., Vangheluwe, P. & Andersen, J. P., 16 Mar 2018, In : Journal of Biological Chemistry. 293, p. 3880-3889

Mutational Analysis of a Peripheral Pathway for Phospholipid Transport in ATP8A2: Poster at the 15th International Conference on Na,K-ATPase and Related Transport ATPases, Otsu, Japan, 2017

Mogensen, L., Mikkelsen, S., Gantzel, R., Coleman, J. A., Vilsen, B., S. Molday, R., Vestergaard, A. L. & Andersen, J. P., 24 Sep 2017. 1 p.

N905 of TM6 is crucial to the function of the mammalian flippase ATP8A2: Poster at the 15th International Conference on Na,K-ATPase and Related Transport ATPases, Otsu, Japan, 2017

Mikkelsen, S., Mogensen, L., Gantzel, R., Vilsen, B., S. Molday, R., Vestergaard, A. L. & Andersen, J. P., 24 Sep 2017. 1 p.

Towards the structure of yeast and mammalian P4-ATPases: Poster at the 15th International Conference on Na,K-ATPase and Related Transport ATPases, Otsu, Japan, 2017

Lyons, J., Laban, M., Mikkelsen, S., Ulstrup, J., Mogensen, L. S., Montigny, C., Ash, M-R., Molday, R. S., Frauenfeld, J., Andersen, J. P., Lenoir, G. & Nissen, P., 24 Sep 2017. 1 p.

Disease mutations reveal residues critical to the interaction of P4-ATPases with lipid substrates

Gantzel, R. H., Mogensen, L. S., Mikkelsen, S. A., Vilsen, B., Molday, R. S., Vestergaard, A. L. & Andersen, J. P., 5 Sep 2017, In : Scientific Reports. 7, 1, p. 10418 11 p., doi: 10.1038/s41598-017-10741-z.

Review: P4-ATPases as Phospholipid Flippases-Structure, Function, and Enigmas

Andersen, J. P., Vestergaard, A. L., Mikkelsen, S. A., Mogensen, L. S., Chalat, M. & Molday, R. S., 2016, In : Frontiers in Physiology. 7, p. 275 (23 pages) 23 p.

Specific mutations in mammalian P4-ATPase ATP8A2 catalytic subunit entail differential glycosylation of the accessory CDC50A subunit

Vestergaard, A. L., Mikkelsen, S. A., Coleman, J. A., Molday, R. S., Vilsen, B. & Andersen, J. P., 22 Nov 2015, In : FEBS Letters. 589, p. 3908-3914 7 p.

Biochemical characterization of P4-ATPase mutations associated with Intrahepatic Cholestatic Disease

Gantzel, R., Vestergaard, A. L., Mikkelsen, S., Molday, R. S. & Andersen, J. P., 20 Sep 2015.

Analysis of amino acid residues of potential importance for phosphatidylserine specificity of P4-type ATPase ARP8A2

Mogensen, L., Vestergaard, A. L., Mikkelsen, S., Coleman, J. A., Vilsen, B., Molday, R. S. & Andersen, J. P., 28 Jun 2015.

Scanning mutagenesis of transmembrane segments M5 and M6 of the mammalian flippase ATP8A2 – evidence for a classic transport pathway?

Mikkelsen, S., Vestergaard, A. L., Coleman, J. A., Vilsen, B., S. Molday, R. & Andersen, J. P., 28 Jun 2015. 1 p.

Biochemical Characterization of P4-ATPase Mutations Associated with Intrahepatic Cholestatic Disease

Gantzel, R., Vestergaard, A. L., Mikkelsen, S., S. Molday, R. & Andersen, J. P., 2015. 1 p.

Analysis of Amino Acid Residues of Potential Importance for Phosphati-dylserine Specificity of P4-type ATPase ATP8A2

Mogensen, L., Vestergaard, A. L., Mikkelsen, S., Coleman, J. A., Vilsen, B., Molday, R. S. & Andersen, J. P., Aug 2014. 1 p.

Darier disease mutation E917K of SERCA2b relieves the inhibitory influence of the 11th transmembrane segment

Mikkelsen, S., Holdensen, A. N., Vangheluwe, P., Vilsen, B. & Andersen, J. P., Aug 2014.

Stability cluster links hydrofobic gate to K873 in ATP8A2

Mikkelsen, S., Vestergaard, A. L., Coleman, J. A., Vilsen, B., Molday, R. S. & Andersen, J. P., Aug 2014.

Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2

Vestergaard, A. L., Coleman, J. A., Lemmin, T., Mikkelsen, S. A., Molday, L. L., Vilsen, B., Molday, R. S., Dal Peraro, M. & Andersen, J. P., 8 Apr 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 14, p. E1334-43 10 p.

Biochemical Characterization of P4-ATPase Mutations Associated with Intrahepatic Cholestatic Disease

Gantzel, R., Vestergaard, A. L., Mikkelsen, S., Molday, R. S. & Andersen, J. P., 2014. 1 p.

Functional impacts of the Darier Disease mutation E917K/E918K and addition of two different tails to SERCA

Mikkelsen, S., Holdensen, A. N., Vilsen, B. & Andersen, J. P., 2012.

Darier disease mutation E917K/E918K of SERCA causes accumulation of the E2 form: Poster for the 13th international ATPase conference, Pacific Grove, CA, USA.

Mikkelsen, S., Holdensen, A. N., Vilsen, B. & Andersen, J. P., 30 Sep 2011. 1 p.