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Stig Purup

Adj. Professor, Aalborg University, Senior Researcher

Stig Purup
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My main interests are applied cell biology, bioactive components and lactation physiology.

The research includes investigation of bioactive components in food and feedstuff and their importance for the nutritional and health beneficial effect. Focus is natural occurring compounds, compounds from outside, and compounds that have been either added or synthesised as a result of cultivation production, manufacture or storage. The importance and physiological effects of the bioactive components in consumers and animals is studied by use of in vitro cell-based models and experimental animals.

A specific research area of interest is bioactive components in natural mixtures such as milk, blood and plant- and tissue extracts. Bioactive components of current interest are growth factors, hormones, fatty acids, vitamins, selenoproteins, phytoestrogens, mycotoxins and polyacetylenes. The obtained knowledge can be used for development of improved methods for prevention and treatment of diseases in humans and animals, and increased quality and safety in food production.

The research also includes the lactation physiology associated with regulation, synthesis and secretion of bioactive components from the mammary gland into the milk. Our team is proficient in isolation of primary mammary epithelial cells and establishment of cell models for studying physiological development of the bovine mammary gland and lactogenesis.

Establishment of a 3D-biosynthesis platform for in vitro milk production based on mammary epithelial cell cultures is central in our ongoing research for developing the biotechnology to produce a sustainable alternative to cow´s milk, thereby reduce greenhouse gases emission in the long term.

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