Steen Jakobsen

  1. Journal article
  2. Published

    Results from (11)C-metformin-PET scans, tissue analysis and cellular drug-sensitivity assays questions the view that biguanides affects tumor respiration directly. / Iversen, Ane B; Horsman, Michael R; Jakobsen, Steen; Jensen, Jonas B; Garm, Christian; Jessen, Niels; Breining, Peter; Frøkiær, Jørgen; Busk, Morten.

    In: Scientific Reports, Vol. 7, No. 1, 9436, 25.08.2017, p. 9436.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    A PET Tracer for Renal Organic Cation Transporters, 11C-metformin: Radiosynthesis and Preclinical Proof-of-Concept Studies. / Jakobsen, Steen; Busk, Morten; Jensen, Jonas Brorson; Munk, Ole Lajord; Zois, Nora Elisabeth; Alstrup, Aage Kristian Olsen; Jessen, Niels; Frøkiær, Jørgen.

    In: Journal of Nuclear Medicine, Vol. 57(4), 01.04.2016, p. 615-621.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Detection of alpha2-adrenergic receptors in brain of living pig with 11C-yohimbine. / Jakobsen, Steen; Pedersen, K.; Smith, Donald F.; Jensen, S. B.; Munk, Ole Lajord; Cumming, Paul.

    In: J. Nucl. Med., No. 47, 2006, p. 2008-2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Detection of {alpha}2-Adrenergic Receptors in Brain of Living Pig with 11C-Yohimbine. / Jakobsen, Steen; Pedersen, Kasper; Smith, Donald F.; Jensen, Svend Borup; Munk, Ole Lajord; Cumming, Paul.

    In: The Journal of Nuclear Medicine, Vol. 47, No. 12, 2006, p. 2008-2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Synthesis, radiolabeling and in vivo evaluation of [11C]RAL-01, a potential phosphodiesterase 5 radioligand. / Jakobsen, Steen; Kodahl, G.M.; Olsen, Aage K.; Cumming, Paul.

    In: Nucl. Med. Biol., No. 33, 2006, p. 593-597.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    [11C]-metformin distribution in the liver and small intestine using dynamic PET in mice demonstrates tissue-specific transporter dependency. / Jensen, Jonas B; Sundelin, Elias I; Jakobsen, Steen; Gormsen, Lars C; Munk, Ole L; Frøkiær, Jørgen; Jessen, Niels.

    In: Diabetes, 06.2016, p. 1724-1730.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Cholinergic PET imaging in infections and inflammation using 11C-donepezil and 18F-FEOBV. / Jørgensen, Nis Pedersen; Alstrup, Aage Kristian Olsen; Mortensen, Frank Viborg; Knudsen, Karoline; Jakobsen, Steen; Madsen, Line Bille; Bender, Dirk; Breining, Peter; Petersen, Mikkel Steen; Schleimann, Mariane Høgsbjerg; Dagnæs-Hansen, Frederik; Gormsen, Lars Christian; Borghammer, Per.

    In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 44, No. 3, 03.2017, p. 449–458.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Imaging Imidazoline-I2 Binding Sites in Porcine Brain Using 11C-BU99008. / Kealey, Steven; Turner, Emma M; Husbands, Stephen M; Salinas, Cristian A; Jakobsen, Steen; Tyacke, Robin J; Nutt, David J; Parker, Christine A; Gee, Antony D.

    In: Journal of Nuclear Medicine, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Fast diffusion kurtosis imaging of fibrotic mouse kidneys. / Kjølby, Birgitte Fuglsang; Khan, Ahmad Raza; Chuhutin, Andrey; Pedersen, Lea Hougaard; Jensen, Jonas Brorson; Jakobsen, Steen; Zeidler, Dora; Sangill, Ryan; Nyengaard, Jens Randel; Jespersen, Sune Nørhøj; Hansen, Brian.

    In: NMR in Biomedicine, Vol. 29, No. 12, 01.12.2016, p. 1709.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Acute Vagal Nerve Stimulation Lowers α2 Adrenoceptor Availability : Possible Mechanism of Therapeutic Action. / Landau, Anne M.; Dyve, Suzan; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Gjedde, Albert; Doudet, Doris.

    In: Brain Stimulation, Vol. 8, No. 4, 2015, p. 702-707.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Amphetamine challenge decreases yohimbine binding to α2 adrenoceptors in Landrace pig brain. / Landau, Anne M; Doudet, Doris J; Jakobsen, Steen.

    In: Psychopharmacology, Vol. 222, No. 1, 2012, p. 155-163.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Decreased in vivo α2 adrenoceptor binding in the Flinders Sensitive Line rat model of depression. / Landau, Anne M.; Phan, Jenny-Ann; Iversen, Peter; Lillethorup, Thea P; Simonsen, Mette; Wegener, Gregers; Jakobsen, Steen; Doudet, Doris J.

    In: Neuropharmacology, Vol. 91, 04.2015, p. 97-102.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy. / Landau, Anne M.; Alstrup, Aage Kristian Olsen; Audrain, Héléne; Jakobsen, Steen; Simonsen, Mette; Møller, Arne; Videbech, Poul B; Wegener, Gregers; Gjedde, Albert; Doudet, Doris J.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 38, No. 5, 05.2018, p. 881-887.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    In vivo quantification of glial activation in minipigs overexpressing human alpha-synuclein. / Lillethorup, Thea Pinholt; Glud, Andreas Nørgaard; Landeck, Natalie; Alstrup, Aage Kristian Olsen; Jakobsen, Steen; Vang, Kim; Doudet, Doris J.; Brooks, David J.; Kirik, Deniz; Hinz, Rainer; Sorensen, Jens Christian; Landau, Anne M.

    In: Synapse, Vol. 72, No. 12, 22060, 12.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Behavioral response to novelty correlates with dopamine receptor availability in striatum of Göttingen minipigs. / Lind, Nanna Marie; Gjedde, Albert; Moustgaard, Anette; Olsen, Aage K.; Jensen, Svend Borup; Jakobsen, Steen; Arnfred, Sidse Marie; Hansen, Axel Kornerup; Hemmingsen, Ralf Peter; Cumming, Paul.

    In: Behavioural Brain Research, Vol. 164, No. 2, 2005, p. 172-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Mapping the amphetamine-evoked dopamine release in the brain of the Göttingen minipig. / Lind, Nanna Marie; Olsen, Aage K.; Moustgaard, Anette; Jensen, Svend Borup; Jakobsen, Steen; Hansen, Axel Kornerup; Arnfred, Sidse Marie; Hemmingsen, Ralf Peter; Gjedde, Albert; Cumming, Paul.

    In: Brain Research Bulletin, Vol. 65, No. 1, 2005, p. 1-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Exogenous dopamine reduces GABA receptor availability in the human brain. / Lou, Hans Olav Christensen; Rosenstand, Astrid; Brooks, David J; Bender, Dirk; Jakobsen, Steen; Blicher, Jakob U; Hansen, Kim V; Møller, Arne.

    In: Brain and Behavior, Vol. 6, No. 7, 07.2016, p. e00484.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Biodistribution and radiation dosimetry of [N-methyl-11C]mirtazapine, an antidepressant affecting adrenoceptors. / Marthi, Katalin; Hansen, Søren B; Jakobsen, Steen; Bender, Dirk; Smith, Stefan Bo; Smith, Donald F.

    In: Applied Radiation and Isotopes, Vol. 59, No. 2-3, 2012, p. 175-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    [N-methyl-11C]Mirtazapine for positron emission tomography neuroimaging of antidepressant actions in humans. / Marthi, Katalin; Jakobsen, Steen; Bender, Dirk; Hansen, Søren B; Smith, Stefan Bo; Hermansen, Flemming; Rosenberg, Raben; Smith, Donald F.

    In: Psychopharmacology, Vol. 174, No. 2, 2004, p. 260-5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Radiosynthesis and evaluation of 1-substituted 3-(2,3-dihydro-1H-inden-2-yl)-6-(1-ethylpropyl)-(3R,6R)-2,5-piperazinedione derivatives as PET tracers for imaging the central oxytocinergic system. / Marzano, Carmine; Jakobsen, Steen; Salinas, Cristian; Tang, Sac Pham; Bender, Dirk; Passchier, Jan; Plisson, Christophe.

    In: Journal of Labelled Compounds and Radiopharmaceuticals, Vol. 60, No. 12, 10.2017, p. 556-565.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    PET imaging of patients with non-small cell lung cancer employing an EGF receptor targeting drug as tracer. / Memon, A A; Weber, B; Winterdahl, M; Jakobsen, S; Meldgaard, P; Madsen, H H T; Keiding, S; Nexo, E; Sorensen, B S.

    In: B J C, Vol. 105, No. 12, 2011, p. 1850-5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Positron emission tomography (PET) imaging with [11C]-labeled erlotinib: a micro-PET study on mice with lung tumor xenografts. / Memon, Ashfaque A; Jakobsen, Steen; Dagnaes-Hansen, Frederik; Sørensen, Boe Sandahl; Keiding, Susanne; Nexø, Ebba.

    In: Cancer research, Vol. 69, No. 3, 2009, p. 873-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Hyperpolarized [1-13C]-acetate Renal Metabolic Clearance Rate Mapping. / Mikkelsen, Emmeli F R; Mariager, Christian Østergaard; Nørlinger, Thomas; Qi, Haiyun; Schulte, Rolf F; Jakobsen, Steen; Frøkiær, Jørgen; Pedersen, Michael; Stødkilde-Jørgensen, Hans; Laustsen, Christoffer.

    In: Scientific Reports, Vol. 7, No. 1, 22.11.2017, p. 16002.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Publisher Correction : Hyperpolarized [1-C]-acetate Renal Metabolic Clearance Rate Mapping. / Mikkelsen, Emmeli F R; Mariager, Christian Østergaard; Nørlinger, Thomas; Qi, Haiyun; Schulte, Rolf F; Jakobsen, Steen; Frøkiær, Jørgen; Pedersen, Michael; Stødkilde-Jørgensen, Hans; Laustsen, Christoffer.

    In: Scientific Reports, Vol. 8, No. 1, 20.07.2018, p. 11235.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Accessing radiation response using hypoxia PET imaging and oxygen sensitive electrodes: a preclinical study. / Mortensen, Lise Saksø; Busk, Morten; Nordsmark, Marianne; Jakobsen, Steen; Theil, Jørn; Overgaard, Jens; Horsman, Michael R.

    In: Radiotherapy & Oncology, Vol. 99, No. 3, 2011, p. 418-23.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review