Steen Jakobsen

  1. Journal article
  2. Published

    Effects of anesthesia and species on the uptake or binding of radioligands in vivo in the Göttingen minipig. / Alstrup, Aage Kristian Olsen; Landau, Anne M.; Holden, James E; Jakobsen, Steen; Schacht, Anna C Schacht; Audrain, Hélène; Wegener, Gregers; Hansen, Axel K; Gjedde, Albert; Doudet, Doris.

    In: BioMed Research International, Vol. 2013, No. 808713, 15.07.2013, p. 1-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Dopamine D3 receptor antagonists: the quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in vivo studies. / Bennacef, Idriss; Salinas, Cristian A; Bonasera, Thomas A; Gunn, Roger N; Audrain, Hélène; Jakobsen, Steen; Nabulsi, Nabeel; Weinzimmer, David; Carson, Richard E; Huang, Yiyun; Holmes, Ian; Micheli, Fabrizio; Heidbreder, Christian; Gentile, Gabriella; Rossi, Tino; Laruelle, Marc.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 19, No. 17, 2009, p. 5056-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Metformin Targets Brown Adipose Tissue in vivo and Reduces Oxygen Consumption in vitro. / Breining, Peter; Jensen, Jonas B; Sundelin, Elias I; Gormsen, Lars C; Jakobsen, Steen; Busk, Morten; Rolighed, Lars; Bross, Peter; Fernandez-Guerra, Paula; Markussen, Lasse K; Rasmussen, Nanna E; Hansen, Jacob B; Pedersen, Steen B; Richelsen, Bjørn; Jessen, Niels.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. 9, 09.2018, p. 2264-2273.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Assessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET. / Busk, Morten; Munk, Ole Lajord; Jakobsen, Steen; Wang, Tobias; Skals, Marianne; Steiniche, Torben; Horsman, Michael Robert; Overgaard, Jens.

    In: Acta Oncologica, Vol. 49, No. 7, 2010, p. 922-33.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Can hypoxia-PET map hypoxic cell density heterogeneity accurately in an animal tumor model at a clinically obtainable image contrast? / Busk, Morten; Horsman, Michael Robert; Jakobsen, Steen; Hansen, Kim V; Bussink, Johan; van der Kogel, Albert; Overgaard, Jens.

    In: Radiotherapy & Oncology, Vol. 92, No. 3, 09.2009, p. 429-436.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Cellular uptake of PET tracers of glucose metabolism and hypoxia and their linkage. / Busk, Morten; Horsman, Michael R; Jakobsen, Steen; Bussink, Johan; van der Kogel, Albert; Overgaard, Jens.

    In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 35, No. 12, 12.2008, p. 2294-303.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Dual-tracer PET of viable tumor volume and hypoxia for identification of necrosis-containing radio-resistant Sub-volumes. / Busk, Morten; Horsman, Michael R.; Overgaard, Jens; Jakobsen, Steen.

    In: Acta Oncologica, Vol. 58, No. 10, 2019, p. 1476-1482.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    FDG-PET reproducibility in tumor-bearing mice: comparing a traditional SUV approach with a tumor-to-brain tissue ratio approach. / Busk, Morten; Munk, Ole L; Jakobsen, Steen; Frøkiær, Jørgen; Overgaard, Jens; Horsman, Michael R.

    In: Acta oncologica (Stockholm, Sweden), Vol. 56, No. 5, 05.2017, p. 706-712.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Hypoxia positron emission tomography imaging: combining information on perfusion and tracer retention to improve hypoxia specificity. / Busk, Morten; Munk, Ole L; Jakobsen, Steen S; Horsman, Michael R.

    In: Acta Oncologica, Vol. 56, No. 11, 11.2017, p. 1583-1590.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Imaging Hypoxia in Xenografted and Murine Tumors with 18F-Fluoroazomycin Arabinoside: A Comparative Study Involving microPET, Autoradiography, pO2-Polarography, and Fluorescence Microscopy. / Busk, Morten; Horsman, Michael R; Jakobsen, Steen; Keiding, Susanne; van der Kogel, Albert J; Bussink, Johan; Overgaard, Jens.

    In: International Journal of Radiation Oncology, Biology, Physics, Vol. 70, No. 4, 15.03.2008, p. 1202-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    In vivo Identification and Specificity assessment of mRNA markers of hypoxia in human and mouse tumors. / Busk, Morten; Toustrup, Kasper; Soerensen, Brita S; Alsner, Jan; Horsman, Michael R; Jakobsen, Steen; Overgaard, Jens.

    In: B M C Cancer, Vol. 11, No. 1, 09.02.2011, p. 63.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Inhibition of tumor lactate oxidation: consequences for the tumor microenvironment. / Busk, Morten; Walenta, Stefan; Mueller-Klieser, Wolfgang; Steiniche, Torben; Jakobsen, Steen; Horsman, Michael Robert; Overgaard, Jens.

    In: Radiotherapy & Oncology, 2011, p. 404-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    PET hypoxia imaging with FAZA: reproducibility at baseline and during fractionated radiotherapy in tumour-bearing mice. / Busk, Morten; Mortensen, Lise Saksø; Nordsmark, M; Overgaard, J; Jakobsen, S; Hansen, K V; Theil, J; Kallehauge, Jesper; D'Andrea, F P; Steiniche, T; Horsman, M R.

    In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 40, No. 2, 01.2013, p. 186-97.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    PET imaging of tumor hypoxia using 18F-labeled pimonidazole. / Busk, Morten; Jakobsen, Steen; Horsman, Michael R; Mortensen, Lise S; Iversen, Ane Bundsbæk; Overgaard, Jens; Nordsmark, Marianne; Ji, Xiaosheng; Lee, David Y; Raleigh, James R.

    In: Acta Oncologica, Vol. 52, No. 7, 2013, p. 1300-1307.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 &2 and AMP-activated Protein Kinase in the Kidney. / Christensen, Michael; Jensen, Jonas B; Jakobsen, Steen; Jessen, Niels; Frøkiær, Jørgen; Kemp, Bruce E; Marciszyn, Allison L; Li, Hui; Pastor-Soler, Núria M; Hallows, Kenneth R; Nørregaard, Rikke.

    In: Scientific Reports, Vol. 6, 35952, 26.10.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published
  18. Published

    A PET study of effects of chronic 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on serotonin markers in Göttingen minipig brain. / Cumming, Paul; Møller, Mette; Benda, Kjeld; Minuzzi, Luciano; Jakobsen, Steen; Jensen, Svend B; Pakkenberg, Bente; Stark, Anette K; Gramsbergen, Jan Bert; Andreasen, Mette F; Olsen, Aage K.

    In: Synapse, Vol. 61, No. 7, 2007, p. 478-87.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Biodistribution of [ 11C]-metformin and mRNA expression of placentae metformin transporters in the pregnant chinchilla. / Dahl Andersen, Maria; Duvald, Christina Søndergaard; Vendelbo, Mikkel; Pedersen, Steen Bønløkke; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Mikkelsen, Emmeli; Ovesen, Per Glud; Pedersen, Michael.

    In: Contrast Media & Molecular Imaging, Vol. 2019, 9787340, 30.04.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    [N-methyl-11C]cholylsarcosine, a novel bile acid tracer for PET/CT of hepatic excretory function : Radiosynthesis and proof-of-concept studies in pigs. / Frisch, Kim; Jakobsen, Steen; Sørensen, Michael; Munk, Ole Lajord; Alstrup, Aage K O; Ott, Peter; Hofmann, Alan F; Keiding, Susanne.

    In: Journal of Nuclear Medicine, Vol. 53, No. 5, 2012, p. 772-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    In Vivo Imaging of Human Acetylcholinesterase Density in Peripheral Organs Using 11C-Donepezil : Dosimetry, Biodistribution, and Kinetic Analyses. / Gjerløff, Trine; Jakobsen, Steen; Nahimi, Adjmal; Munk, Ole L; Bender, Dirk; Alstrup, Aage K O; Vase, Karina H; Brooks, David J; Borghammer, Per.

    In: Journal of Nuclear Medicine, Vol. 55, No. 11, 2014, p. 1818-24.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Visualization of intrathecal delivery by PET-imaging. / Glud, Andreas Nørgaard; Jakobsen, Steen; Landau, Anne; Alstrup, Aage Kristian Olsen; Sorensen, Jens Christian.

    In: Journal of Neuroscience Methods, Vol. 317, 07.02.2019, p. 45-48.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    In Vivo Imaging of Human 11C-Metformin in Peripheral Organs: Dosimetry, Biodistribution and Kinetic Analyses. / Gormsen, Lars Christian; Sundelin, Elias Immanuel; Jensen, Jonas Brorson; Vendelbo, Mikkel Holm; Jakobsen, Steen; Munk, Ole Lajord; Christensen, Mette Marie Hougaard; Brøsen, Kim; Frøkiær, Jørgen; Jessen, Niels.

    In: The Journal of Nuclear Medicine, 28.07.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Metformin does not Affect Postabsorptive Hepatic Free Fatty Acid Uptake, Oxidation or Resecretion in Humans : A 3-months Placebo Controlled Clinical Trial in Patients with Type 2 Diabetes and Healthy Controls. / Gormsen, Lars C; Søndergaard, Esben; Christensen, Nana L; Jakobsen, Steen; Nielsen, Erik H T; Munk, Ole L; Tolbod, Lars P; Jessen, Niels; Nielsen, Søren.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. 6, 06.2018, p. 1435-1444.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Evaluation of ECG-gated [(11)C]acetate PET for measuring left ventricular volumes, mass, and myocardial external efficiency. / Hansson, Nils Henrik; Tolbod, Lars; Harms, Hans; Wiggers, Henrik; Kim, Won Yong; Søvsø Szocska Hansen, Esben; Zaremba, Tomas; Frøkiær, Jørgen; Jakobsen, Steen; Sørensen, Jens.

    In: Journal of Nuclear Cardiology, 19.04.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Automatic extraction of myocardial mass and volumes using parametric images from dynamic nongated PET. / Harms, Hendrik Johannes; Hansson, Nils Henrik Stubkjær; Tolbod, Lars Poulsen; Kim, Won Yong; Jakobsen, Steen; Bouchelouche, Kirsten; Wiggers, Henrik; Frøkiaer, Jørgen; Sörensen, Jens.

    In: Journal of Nuclear Medicine, Vol. 57, No. 9, 28.04.2016, p. 1382-87.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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