Steen Jakobsen

  1. Journal article › Research › Peer-reviewed
  2. Published

    A PET Tracer for Renal Organic Cation Transporters, 11C-metformin: Radiosynthesis and Preclinical Proof-of-Concept Studies. / Jakobsen, Steen; Busk, Morten; Jensen, Jonas Brorson; Munk, Ole Lajord; Zois, Nora Elisabeth; Alstrup, Aage Kristian Olsen; Jessen, Niels; Frøkiær, Jørgen.

    In: Journal of Nuclear Medicine, Vol. 57(4), 01.04.2016, p. 615-621.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    A PET study of effects of chronic 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on serotonin markers in Göttingen minipig brain. / Cumming, Paul; Møller, Mette; Benda, Kjeld; Minuzzi, Luciano; Jakobsen, Steen; Jensen, Svend B; Pakkenberg, Bente; Stark, Anette K; Gramsbergen, Jan Bert; Andreasen, Mette F; Olsen, Aage K.

    In: Synapse, Vol. 61, No. 7, 2007, p. 478-87.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Accessing radiation response using hypoxia PET imaging and oxygen sensitive electrodes: a preclinical study. / Mortensen, Lise Saksø; Busk, Morten; Nordsmark, Marianne; Jakobsen, Steen; Theil, Jørn; Overgaard, Jens; Horsman, Michael R.

    In: Radiotherapy & Oncology, Vol. 99, No. 3, 2011, p. 418-23.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Acute Vagal Nerve Stimulation Lowers α2 Adrenoceptor Availability : Possible Mechanism of Therapeutic Action. / Landau, Anne M.; Dyve, Suzan; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Gjedde, Albert; Doudet, Doris.

    In: Brain Stimulation, Vol. 8, No. 4, 2015, p. 702-707.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Amphetamine challenge decreases yohimbine binding to α2 adrenoceptors in Landrace pig brain. / Landau, Anne M; Doudet, Doris J; Jakobsen, Steen.

    In: Psychopharmacology, Vol. 222, No. 1, 2012, p. 155-163.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Assessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET. / Busk, Morten; Munk, Ole Lajord; Jakobsen, Steen; Wang, Tobias; Skals, Marianne; Steiniche, Torben; Horsman, Michael Robert; Overgaard, Jens.

    In: Acta Oncologica, Vol. 49, No. 7, 2010, p. 922-33.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Automatic extraction of myocardial mass and volumes using parametric images from dynamic nongated PET. / Harms, Hendrik Johannes; Hansson, Nils Henrik Stubkjær; Tolbod, Lars Poulsen; Kim, Won Yong; Jakobsen, Steen; Bouchelouche, Kirsten; Wiggers, Henrik; Frøkiaer, Jørgen; Sörensen, Jens.

    In: Journal of Nuclear Medicine, Vol. 57, No. 9, 28.04.2016, p. 1382-87.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Behavioral response to novelty correlates with dopamine receptor availability in striatum of Göttingen minipigs. / Lind, Nanna Marie; Gjedde, Albert; Moustgaard, Anette; Olsen, Aage K.; Jensen, Svend Borup; Jakobsen, Steen; Arnfred, Sidse Marie; Hansen, Axel Kornerup; Hemmingsen, Ralf Peter; Cumming, Paul.

    In: Behavioural Brain Research, Vol. 164, No. 2, 2005, p. 172-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Behaviour of [11C]R(-)- and [11C]S(+)-rolipram in vitro and in vivo, and their use as PET radiotracers for the quantificative assay of PDE4. / Parker, Christine A; Matthews, Julian C; Gunn, Roger N; Martarello, Laurent; Cunningham, Vincent J; Dommett, David; Knibb, Stephen T; Bender, Dirk; Jakobsen, Steen; Brown, John; Gee, Antony D.

    In: Synapse, Vol. 55, No. 4, 2005, p. 270-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Biodistribution and radiation dosimetry of [N-methyl-11C]mirtazapine, an antidepressant affecting adrenoceptors. / Marthi, Katalin; Hansen, Søren B; Jakobsen, Steen; Bender, Dirk; Smith, Stefan Bo; Smith, Donald F.

    In: Applied Radiation and Isotopes, Vol. 59, No. 2-3, 2012, p. 175-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Biodistribution of [ 11C]-metformin and mRNA expression of placentae metformin transporters in the pregnant chinchilla. / Dahl Andersen, Maria; Duvald, Christina Søndergaard; Vendelbo, Mikkel; Pedersen, Steen Bønløkke; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Mikkelsen, Emmeli; Ovesen, Per Glud; Pedersen, Michael.

    In: Contrast Media & Molecular Imaging, Vol. 2019, 9787340, 30.04.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Can hypoxia-PET map hypoxic cell density heterogeneity accurately in an animal tumor model at a clinically obtainable image contrast? / Busk, Morten; Horsman, Michael Robert; Jakobsen, Steen; Hansen, Kim V; Bussink, Johan; van der Kogel, Albert; Overgaard, Jens.

    In: Radiotherapy & Oncology, Vol. 92, No. 3, 09.2009, p. 429-436.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Cellular uptake of PET tracers of glucose metabolism and hypoxia and their linkage. / Busk, Morten; Horsman, Michael R; Jakobsen, Steen; Bussink, Johan; van der Kogel, Albert; Overgaard, Jens.

    In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 35, No. 12, 12.2008, p. 2294-303.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Cholinergic PET imaging in infections and inflammation using 11C-donepezil and 18F-FEOBV. / Jørgensen, Nis Pedersen; Alstrup, Aage Kristian Olsen; Mortensen, Frank Viborg; Knudsen, Karoline; Jakobsen, Steen; Madsen, Line Bille; Bender, Dirk; Breining, Peter; Petersen, Mikkel Steen; Schleimann, Mariane Høgsbjerg; Dagnæs-Hansen, Frederik; Gormsen, Lars Christian; Borghammer, Per.

    In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 44, No. 3, 03.2017, p. 449–458.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Decreased in vivo α2 adrenoceptor binding in the Flinders Sensitive Line rat model of depression. / Landau, Anne M.; Phan, Jenny-Ann; Iversen, Peter; Lillethorup, Thea P; Simonsen, Mette; Wegener, Gregers; Jakobsen, Steen; Doudet, Doris J.

    In: Neuropharmacology, Vol. 91, 04.2015, p. 97-102.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Detection of alpha2-adrenergic receptors in brain of living pig with 11C-yohimbine. / Jakobsen, Steen; Pedersen, K.; Smith, Donald F.; Jensen, S. B.; Munk, Ole Lajord; Cumming, Paul.

    In: J. Nucl. Med., No. 47, 2006, p. 2008-2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Detection of {alpha}2-Adrenergic Receptors in Brain of Living Pig with 11C-Yohimbine. / Jakobsen, Steen; Pedersen, Kasper; Smith, Donald F.; Jensen, Svend Borup; Munk, Ole Lajord; Cumming, Paul.

    In: The Journal of Nuclear Medicine, Vol. 47, No. 12, 2006, p. 2008-2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Dopamine D3 receptor antagonists: the quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in vivo studies. / Bennacef, Idriss; Salinas, Cristian A; Bonasera, Thomas A; Gunn, Roger N; Audrain, Hélène; Jakobsen, Steen; Nabulsi, Nabeel; Weinzimmer, David; Carson, Richard E; Huang, Yiyun; Holmes, Ian; Micheli, Fabrizio; Heidbreder, Christian; Gentile, Gabriella; Rossi, Tino; Laruelle, Marc.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 19, No. 17, 2009, p. 5056-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Dual-tracer PET of viable tumor volume and hypoxia for identification of necrosis-containing radio-resistant Sub-volumes. / Busk, Morten; Horsman, Michael R.; Overgaard, Jens; Jakobsen, Steen.

    In: Acta Oncologica, Vol. 58, No. 10, 2019, p. 1476-1482.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Early synaptic dysfunction induced by α-synuclein in a rat model of Parkinson's disease. / Phan, Jenny-Ann; Stokholm, Kathrine; Zareba-Paslawska, Justyna; Jakobsen, Steen; Vang, Kim; Gjedde, Albert; Landau, Anne M; Romero-Ramos, Marina.

    In: Scientific Reports, Vol. 7, No. 1, 6363, 25.07.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Effects of anesthesia and species on the uptake or binding of radioligands in vivo in the Göttingen minipig. / Alstrup, Aage Kristian Olsen; Landau, Anne M.; Holden, James E; Jakobsen, Steen; Schacht, Anna C Schacht; Audrain, Hélène; Wegener, Gregers; Hansen, Axel K; Gjedde, Albert; Doudet, Doris.

    In: BioMed Research International, Vol. 2013, No. 808713, 15.07.2013, p. 1-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy. / Landau, Anne M.; Alstrup, Aage Kristian Olsen; Audrain, Héléne; Jakobsen, Steen; Simonsen, Mette; Møller, Arne; Videbech, Poul B; Wegener, Gregers; Gjedde, Albert; Doudet, Doris J.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 38, No. 5, 05.2018, p. 881-887.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Erratum to : Evaluation of ECG-gated [(11)C]acetate PET for measuring left ventricular volumes, mass, and myocardial external efficiency. / Stubkjær Hansson, Nils Henrik; Tolbod, Lars; Harms, Hendrik Johannes; Wiggers, Henrik; Kim, Won Yong; Hansen, Esben; Zaremba, Tomas; Frøkiær, Jørgen; Jakobsen, Steen; Sørensen, Jens.

    In: Journal of Nuclear Cardiology, Vol. 23, No. 5, 11.05.2016, p. 1232-1232.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Evaluation of ECG-gated [(11)C]acetate PET for measuring left ventricular volumes, mass, and myocardial external efficiency. / Hansson, Nils Henrik; Tolbod, Lars; Harms, Hans; Wiggers, Henrik; Kim, Won Yong; Søvsø Szocska Hansen, Esben; Zaremba, Tomas; Frøkiær, Jørgen; Jakobsen, Steen; Sørensen, Jens.

    In: Journal of Nuclear Cardiology, 19.04.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Exogenous dopamine reduces GABA receptor availability in the human brain. / Lou, Hans Olav Christensen; Rosenstand, Astrid; Brooks, David J; Bender, Dirk; Jakobsen, Steen; Blicher, Jakob U; Hansen, Kim V; Møller, Arne.

    In: Brain and Behavior, Vol. 6, No. 7, 07.2016, p. e00484.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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