Steen Jakobsen

  1. Published

    Biodistribution of [ 11C]-metformin and mRNA expression of placentae metformin transporters in the pregnant chinchilla. / Dahl Andersen, Maria; Duvald, Christina Søndergaard; Vendelbo, Mikkel; Pedersen, Steen Bønløkke; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Mikkelsen, Emmeli; Ovesen, Per Glud; Pedersen, Michael.

    In: Contrast Media & Molecular Imaging, Vol. 2019, 9787340, 30.04.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  2. Published

    Visualization of intrathecal delivery by PET-imaging. / Glud, Andreas Nørgaard; Jakobsen, Steen; Landau, Anne; Alstrup, Aage Kristian Olsen; Sorensen, Jens Christian.

    In: Journal of Neuroscience Methods, Vol. 317, 07.02.2019, p. 45-48.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Dual-tracer PET of viable tumor volume and hypoxia for identification of necrosis-containing radio-resistant Sub-volumes. / Busk, Morten; Horsman, Michael R.; Overgaard, Jens; Jakobsen, Steen.

    In: Acta Oncologica, Vol. 58, No. 10, 2019, p. 1476-1482.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Hepatic exposure of metformin in patients with non-alcoholic fatty liver disease. / Sundelin, Elias Immanuel Ordell; Gormsen, Lars Christian; Heebøll, Sara; Vendelbo, Mikkel Holm; Jakobsen, Steen; Munk, Ole Lajord; Feddersen, Søren; Brøsen, Kim; Hamilton-Dutoit, Stephen Jacques; Pedersen, Steen Bønløkke; Grønbaek, Henning; Jessen, Niels.

    In: British Journal of Clinical Pharmacology, Vol. 85, No. 8, 2019, p. 1761-1770.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Sucrose intake lowers μ-opioid and dopamine D2/3 receptor availability in porcine brain. / Winterdahl, Michael; Noer, Ove; Orlowski, Dariusz; Schacht, Anna C; Jakobsen, Steen; Alstrup, Aage K O; Gjedde, Albert; Landau, Anne.

    In: Scientific Reports, Vol. 9, No. 1, 16918, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    In vivo quantification of glial activation in minipigs overexpressing human alpha-synuclein. / Lillethorup, Thea Pinholt; Glud, Andreas Nørgaard; Landeck, Natalie; Alstrup, Aage Kristian Olsen; Jakobsen, Steen; Vang, Kim; Doudet, Doris J.; Brooks, David J.; Kirik, Deniz; Hinz, Rainer; Sorensen, Jens Christian; Landau, Anne M.

    In: Synapse, Vol. 72, No. 12, 22060, 12.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Metformin Targets Brown Adipose Tissue in vivo and Reduces Oxygen Consumption in vitro. / Breining, Peter; Jensen, Jonas B; Sundelin, Elias I; Gormsen, Lars C; Jakobsen, Steen; Busk, Morten; Rolighed, Lars; Bross, Peter; Fernandez-Guerra, Paula; Markussen, Lasse K; Rasmussen, Nanna E; Hansen, Jacob B; Pedersen, Steen B; Richelsen, Bjørn; Jessen, Niels.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. 9, 09.2018, p. 2264-2273.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Publisher Correction : Hyperpolarized [1-C]-acetate Renal Metabolic Clearance Rate Mapping. / Mikkelsen, Emmeli F R; Mariager, Christian Østergaard; Nørlinger, Thomas; Qi, Haiyun; Schulte, Rolf F; Jakobsen, Steen; Frøkiær, Jørgen; Pedersen, Michael; Stødkilde-Jørgensen, Hans; Laustsen, Christoffer.

    In: Scientific Reports, Vol. 8, No. 1, 20.07.2018, p. 11235.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Metformin does not Affect Postabsorptive Hepatic Free Fatty Acid Uptake, Oxidation or Resecretion in Humans : A 3-months Placebo Controlled Clinical Trial in Patients with Type 2 Diabetes and Healthy Controls. / Gormsen, Lars C; Søndergaard, Esben; Christensen, Nana L; Jakobsen, Steen; Nielsen, Erik H T; Munk, Ole L; Tolbod, Lars P; Jessen, Niels; Nielsen, Søren.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. 6, 06.2018, p. 1435-1444.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy. / Landau, Anne M.; Alstrup, Aage Kristian Olsen; Audrain, Héléne; Jakobsen, Steen; Simonsen, Mette; Møller, Arne; Videbech, Poul B; Wegener, Gregers; Gjedde, Albert; Doudet, Doris J.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 38, No. 5, 05.2018, p. 881-887.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Hyperpolarized [1-13C]-acetate Renal Metabolic Clearance Rate Mapping. / Mikkelsen, Emmeli F R; Mariager, Christian Østergaard; Nørlinger, Thomas; Qi, Haiyun; Schulte, Rolf F; Jakobsen, Steen; Frøkiær, Jørgen; Pedersen, Michael; Stødkilde-Jørgensen, Hans; Laustsen, Christoffer.

    In: Scientific Reports, Vol. 7, No. 1, 22.11.2017, p. 16002.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Radioligand binding analysis of α 2 adrenoceptors with [11C]yohimbine in brain in vivo: Extended Inhibition Plot correction for plasma protein binding. / Phan, Jenny-Ann; Landau, Anne M.; Jakobsen, Steen; Gjedde, Albert.

    In: Scientific Reports, No. 7, 15979, 22.11.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Hypoxia positron emission tomography imaging: combining information on perfusion and tracer retention to improve hypoxia specificity. / Busk, Morten; Munk, Ole L; Jakobsen, Steen S; Horsman, Michael R.

    In: Acta Oncologica, Vol. 56, No. 11, 11.2017, p. 1583-1590.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Genetic Polymorphisms in Organic Cation Transporter 1 Attenuates Hepatic Metformin Exposure in Humans. / Sundelin, Elias; Gormsen, Lars Christian; Jensen, Jonas Brorson; Vendelbo, Mikkel Holm; Jakobsen, Steen; Munk, Ole Lajord; Christensen, Mette Marie Hougaard; Brøsen, Kim; Frøkiaer, Jørgen; Jessen, Niels.

    In: Clinical Pharmacology and Therapeutics, Vol. 102, No. 5, 11.2017, p. 841-848.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published
  16. Published

    Radiosynthesis and evaluation of 1-substituted 3-(2,3-dihydro-1H-inden-2-yl)-6-(1-ethylpropyl)-(3R,6R)-2,5-piperazinedione derivatives as PET tracers for imaging the central oxytocinergic system. / Marzano, Carmine; Jakobsen, Steen; Salinas, Cristian; Tang, Sac Pham; Bender, Dirk; Passchier, Jan; Plisson, Christophe.

    In: Journal of Labelled Compounds and Radiopharmaceuticals, Vol. 60, No. 12, 10.2017, p. 556-565.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Results from (11)C-metformin-PET scans, tissue analysis and cellular drug-sensitivity assays questions the view that biguanides affects tumor respiration directly. / Iversen, Ane B; Horsman, Michael R; Jakobsen, Steen; Jensen, Jonas B; Garm, Christian; Jessen, Niels; Breining, Peter; Frøkiær, Jørgen; Busk, Morten.

    In: Scientific Reports, Vol. 7, No. 1, 9436, 25.08.2017, p. 9436.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Early synaptic dysfunction induced by α-synuclein in a rat model of Parkinson's disease. / Phan, Jenny-Ann; Stokholm, Kathrine; Zareba-Paslawska, Justyna; Jakobsen, Steen; Vang, Kim; Gjedde, Albert; Landau, Anne M; Romero-Ramos, Marina.

    In: Scientific Reports, Vol. 7, No. 1, 6363, 25.07.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    FDG-PET reproducibility in tumor-bearing mice: comparing a traditional SUV approach with a tumor-to-brain tissue ratio approach. / Busk, Morten; Munk, Ole L; Jakobsen, Steen; Frøkiær, Jørgen; Overgaard, Jens; Horsman, Michael R.

    In: Acta oncologica (Stockholm, Sweden), Vol. 56, No. 5, 05.2017, p. 706-712.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Cholinergic PET imaging in infections and inflammation using 11C-donepezil and 18F-FEOBV. / Jørgensen, Nis Pedersen; Alstrup, Aage Kristian Olsen; Mortensen, Frank Viborg; Knudsen, Karoline; Jakobsen, Steen; Madsen, Line Bille; Bender, Dirk; Breining, Peter; Petersen, Mikkel Steen; Schleimann, Mariane Høgsbjerg; Dagnæs-Hansen, Frederik; Gormsen, Lars Christian; Borghammer, Per.

    In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 44, No. 3, 03.2017, p. 449–458.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    In-vivo imaging of a2 adrenoceptors in Parkinson's disease with 11C-yohimbine. / Nahimi, Adjmal; Kinnerup, Martin; Østergaard, K; Winterdahl, Michael; Fedorova, Tatyana D; Jakobsen, Steen; Lund Schaldemose, Jeppe; Sommerauer, Michael Bernhard; Borghammer, Per; Gjedde, Albert.

    In: European Journal of Neurology, No. 24, 2017, p. 594-595.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference articleResearchpeer-review

  22. Published

    Fast diffusion kurtosis imaging of fibrotic mouse kidneys. / Kjølby, Birgitte Fuglsang; Khan, Ahmad Raza; Chuhutin, Andrey; Pedersen, Lea Hougaard; Jensen, Jonas Brorson; Jakobsen, Steen; Zeidler, Dora; Sangill, Ryan; Nyengaard, Jens Randel; Jespersen, Sune Nørhøj; Hansen, Brian.

    In: NMR in Biomedicine, Vol. 29, No. 12, 01.12.2016, p. 1709.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 &2 and AMP-activated Protein Kinase in the Kidney. / Christensen, Michael; Jensen, Jonas B; Jakobsen, Steen; Jessen, Niels; Frøkiær, Jørgen; Kemp, Bruce E; Marciszyn, Allison L; Li, Hui; Pastor-Soler, Núria M; Hallows, Kenneth R; Nørregaard, Rikke.

    In: Scientific Reports, Vol. 6, 35952, 26.10.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    In Vivo Imaging of Human 11C-Metformin in Peripheral Organs: Dosimetry, Biodistribution and Kinetic Analyses. / Gormsen, Lars Christian; Sundelin, Elias Immanuel; Jensen, Jonas Brorson; Vendelbo, Mikkel Holm; Jakobsen, Steen; Munk, Ole Lajord; Christensen, Mette Marie Hougaard; Brøsen, Kim; Frøkiær, Jørgen; Jessen, Niels.

    In: The Journal of Nuclear Medicine, 28.07.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Exogenous dopamine reduces GABA receptor availability in the human brain. / Lou, Hans Olav Christensen; Rosenstand, Astrid; Brooks, David J; Bender, Dirk; Jakobsen, Steen; Blicher, Jakob U; Hansen, Kim V; Møller, Arne.

    In: Brain and Behavior, Vol. 6, No. 7, 07.2016, p. e00484.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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