Steen Jakobsen

  1. 2013
  2. Published

    A model of Parkinson’s Disease in pig and primate by repeated intraventricular administration of an inhibitor of the ubiquitin proteasome system (UPS). / Doudet, Doris; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Møller, Arne; Sørensen, Jens Christian Hedemann; Landau, Anne M.

    2013. Abstract from XX World Congress on Parkinson´s Disease and related disorders, Geneva, Switzerland.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  3. Published

    A model of Parkinson’s disease (PD) in pig and primate by repeated ICV administration of an inhibitor of the ubiquitin proteasome system (UPS). / Doudet, Doris; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Møller, Arne; Sørensen, Jens Christian Hedemann; Landau, Anne M.

    2013. Poster session presented at XX World Congress on Parkinson´s Disease and related disorders, Geneva, Switzerland.

    Research output: Contribution to conferencePosterResearchpeer-review

  4. Published

    Dose response in the binding of 11C-Yohimbine to alpha 2 adrenergic receptors in response to increasing doses of amphetamine. / Doudet, Doris; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Landau, Anne M.

    2013. Poster session presented at The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.

    Research output: Contribution to conferencePosterResearchpeer-review

  5. Published

    Combined PET/microdialysis studies in minipig for PET tracer validation. / Landau, Anne M.; Alstrup, Aage Kristian Olsen; Wegener, Gregers; Jakobsen, Steen; Schacht, Anna C.; Jacobsen, Jan; Mørk, Arne; Sørensen, Jens Christian Hedemann; Doudet, Doris.

    2013. Abstract from Minipig Research Forum, Rom, Italy.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  6. Published

    Longitudinal in vivo imaging in a novel model of Parkinson’s disease in minipig. / Landau, Anne M.; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Schacht, A.C.; Winterdahl, Michael; Møller, Arne; Sørensen, Jens Christian Hedemann; Doudet, Doris.

    2013. Poster session presented at World Parkinson Congress, Montreal, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  7. Published

    PET Imaging Sugar Addiction in Minipigs. / Landau, Anne M.; Møller, Arne; Winterdahl, Michael; Alstrup, Aage Kristian Olsen; Jakobsen, Steen; Schacht, Anna C.; Bender, Dirk; Scheel-Krüger, Jørgen; Kringelbach, Morten L.

    2013. Poster session presented at Scandinavian College of Neuropsychopharmacology, København, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  8. Published

    PET imaging of sugar addiction in minipigs: Effects on the dopamine D2/3 receptor. / Landau, Anne M; Møller, Arne; Winterdahl, Michael; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Schacht, Anne; Bender, Dirk; Scheel-Krüger, Jørgen; Kringelbach, Morten L.

    2013. Poster session presented at The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.

    Research output: Contribution to conferencePosterResearchpeer-review

  9. Published

    Proteasome inhibition model of Parkinson’s disease in Gottingen minipig: Combined dopaminergic and noradrenergic effects. / Landau, Anne M; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Schacht, Anna C.; Møller, Arne; Sørensen, Jens Christian Hedemann; Doudet, Doris.

    2013. Abstract from The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  10. Published
  11. Published

    Molecular Neurobiology of Depression : PET Findings on the Elusive Correlation with Symptom Severity. / Smith, Donald F; Jakobsen, Steen.

    In: Frontiers in Psychiatry, Vol. 4, 2013, p. 8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. 2012
  13. Published

    Update: inhibition plots of [C-11]yohimbine binding yield consistent estimates of non-displaceable volumes of distribution in multiple tests. / Landau, Anne M; Dyve, Suzan; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Doudet, Doris; Gjedde, Albert.

    2012. Abstract from The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain, Baltimore, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  14. Published

    Combined in vivo PET-microdialysis studies of NA release in minipig. / Doudet, Doris; Landau, Annie; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Mørk, Arne; Sørensen, Jens Christian H.; Wegener, Gregers.

    2012. Poster session presented at 28th World CINP, Stockholm, Sweden.

    Research output: Contribution to conferencePosterResearchpeer-review

  15. Published

    Evaluating NA release with C-11 yohimbine: combined in vivo PET-microdialysis studies. / Doudet, Doris; Wegener, Gregers; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Mørk, Arne; Sørensen, Jens Christian Hedemann; Landau, Anne M.

    2012. Abstract from The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain, Baltimore, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  16. Published

    Carbon-11 labelled cholylsarcosine: a PET-tracer for conjugated bile acids. / Frisch, Kim; Jakobsen, Steen; Sørensen, Michael; Munk, Ole Lajord; Alstrup, Aage Kristian Olsen; Ott, Peter; Hofmann, Alan F. ; Keiding, Susanne.

    2012. Poster session presented at Falk Symposium 184, XXII International Bile Acid Meeting, Wien, Austria.

    Research output: Contribution to conferencePosterResearchpeer-review

  17. Published

    Carbon-11 labelling of cholylsarcosine and in vivo imaging of conjugated bile acids by positron emission tomography. / Frisch, Kim; Jakobsen, Steen; Sørensen, Michael; Munk, Ole Lajord; Alstrup, Aage Kristian Olsen; Ott, Peter; Hofmann, Alan F.; Keiding, Susanne.

    2012. Poster session presented at Danish Chemical Society, Odense, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  18. Published

    [N-methyl-11C]cholylsarcosine, a novel bile acid tracer for PET/CT of hepatic excretory function : Radiosynthesis and proof-of-concept studies in pigs. / Frisch, Kim; Jakobsen, Steen; Sørensen, Michael; Munk, Ole Lajord; Alstrup, Aage K O; Ott, Peter; Hofmann, Alan F; Keiding, Susanne.

    In: Journal of Nuclear Medicine, Vol. 53, No. 5, 2012, p. 772-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Imaging Imidazoline-I2 Binding Sites in Porcine Brain Using 11C-BU99008. / Kealey, Steven; Turner, Emma M; Husbands, Stephen M; Salinas, Cristian A; Jakobsen, Steen; Tyacke, Robin J; Nutt, David J; Parker, Christine A; Gee, Antony D.

    In: Journal of Nuclear Medicine, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Amphetamine challenge decreases yohimbine binding to α2 adrenoceptors in Landrace pig brain. / Landau, Anne M; Doudet, Doris J; Jakobsen, Steen.

    In: Psychopharmacology, Vol. 222, No. 1, 2012, p. 155-163.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Displacement of [11C]yohimbine binding in brain reveals noradrenaline release by vagal nerve stimulation. / Landau, Annie; Dyve, Suzan; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Møller, Arne; Doudet, Doris; Gjedde, Albert.

    2012. Abstract from Mind Lab Symposium, Aarhus, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  22. Published

    In vivo alpha2 adrenoceptor binding demonstrates a prolonged effect of electroconvulsive therapy on noradrenergic function in Gottingen minipigs. / Landau, Annie; Wegener, Gregers; Alstrup, Aage Kristian Olsen; Jakobsen, Steen; Audrain, Hélène; Møller, Arne; Simonsen, Mette; Gjedde, Albert; Videbech, Poul; Doudet, Doris.

    2012. Poster session presented at 28th World CINP, Stockholm, Sweden.

    Research output: Contribution to conferencePosterResearchpeer-review

  23. Published

    In vivo alpha2-adrenoceptor-binding viser en forlænget effekt af elektrochok-behandling på den noradrenerge funktion i Göttingen minigrise. / Landau, Annie; Wegener, Gregers; Alstrup, Aage Kristian Olsen; Jakobsen, Steen; Audrain, Hélène; Møller, Arne; Simonsen, Mette; Gjedde, Albert; Videbech, Poul; Doudet, Doris.

    2012. Abstract from Psykiatriens 7. Forskningsdag, Risskov, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  24. Published

    Inhibition plots of [11C]yohimbine binding reveal consistent non-displaceable volumes of distribution in multiple studies. / Landau, Annie; Dyve, Suzan; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Doudet, Doris; Gjedde, Albert.

    2012.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  25. Published

    Kombineret in vivo PET-mikrodialyse studier af noradrenalin frisættelse i minigrise. / Landau, Anne M; Wegener, Gregers; Jakobsen, Steen; Schacht, A.C.; Alstrup, Aage Kristian Olsen; Jacobsen, J.; Mørk, Arne; Sørensen, Jens Christian Hedemann; Doudet, Doris.

    2012. Poster session presented at Psykiatriens 7. Forskningsdag, Aarhus, .

    Research output: Contribution to conferencePosterResearchpeer-review

  26. Published

    Biodistribution and radiation dosimetry of [N-methyl-11C]mirtazapine, an antidepressant affecting adrenoceptors. / Marthi, Katalin; Hansen, Søren B; Jakobsen, Steen; Bender, Dirk; Smith, Stefan Bo; Smith, Donald F.

    In: Applied Radiation and Isotopes, Vol. 59, No. 2-3, 2012, p. 175-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: Results from the DAHANCA 24 trial. / Mortensen, Lise Saksø; Johansen, Jørgen; Kallehauge, Jesper Folsted; Primdahl, Hanne; Busk, Morten; Lassen, Pernille; Alsner, Jan; Sørensen, Brita S; Toustrup, Kasper; Jakobsen, Steen; Petersen, Jørgen; Petersen, Henrik; Theil, Jørn; Nordsmark, Marianne; Overgaard, Jens.

    In: Radiotherapy & Oncology, Vol. 105, No. 1, 10.2012, p. 14-20.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review