Steen Jakobsen

  1. 2010
  2. Published

    Synthesis and in vivo evaluation of [11C]BU99008 as a ligand for the imidazoline I2 binding site. / Kealey, Steven; Husbands, Stephen; Casey, Emma M.; Salinas, Cristian A.; Parker, Christine A.; Jakobsen, Steen; Tyacke, Robin J.; Nutt, David J.; Gee, Antony D.

    In: NeuroImage, Vol. 52, Supplement 1, No. 0, 2010, p. S127 - S128.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference articleResearchpeer-review

  3. 2011
  4. Published

    Accessing radiation response using hypoxia PET imaging and oxygen sensitive electrodes: a preclinical study. / Mortensen, Lise Saksø; Busk, Morten; Nordsmark, Marianne; Jakobsen, Steen; Theil, Jørn; Overgaard, Jens; Horsman, Michael R.

    In: Radiotherapy & Oncology, Vol. 99, No. 3, 2011, p. 418-23.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Inhibition of tumor lactate oxidation: consequences for the tumor microenvironment. / Busk, Morten; Walenta, Stefan; Mueller-Klieser, Wolfgang; Steiniche, Torben; Jakobsen, Steen; Horsman, Michael Robert; Overgaard, Jens.

    In: Radiotherapy & Oncology, 2011, p. 404-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    PET imaging of patients with non-small cell lung cancer employing an EGF receptor targeting drug as tracer. / Memon, A A; Weber, B; Winterdahl, M; Jakobsen, S; Meldgaard, P; Madsen, H H T; Keiding, S; Nexo, E; Sorensen, B S.

    In: B J C, Vol. 105, No. 12, 2011, p. 1850-5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Radiosynthesis and in vivo evaluation of [(11)C]MP-10 as a positron emission tomography radioligand for phosphodiesterase 10A. / Plisson, Christophe; Salinas, Cristian; Weinzimmer, David; Labaree, David; Lin, Shu-Fei; Ding, Yu-Shin; Jakobsen, Steen; Smith, Paul W; Eiji, Kawanishi; Carson, Richard E; Gunn, Roger N; Rabiner, Eugenii A.

    In: Nuclear Medicine and Biology, Vol. 38, No. 6, 2011, p. 875-84.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    The minipig as an animal model to study antidepressant pharmacology by PET. / Landau, Anne M.; Dyve, Suzan; Alstrup, Aage Kristian Olsen; Jakobsen, Steen; Simonsen, Mette; Møller, Arne; Videbech, Poul; Wegener, Gregers; Gjedde, Albert; Doudet, Doris.

    2011. Abstract from NIDA, Florida, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  9. Published

    Tracer kinetic responses to propofol-induced reduction of brain perfusion: Comparison of [11C]Yohimbine and [11C]SCH23390. / Holden, Jim E.; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Doudet, Doris; Landau, Anne M.

    2011. Abstract from XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET, Barcelona, Spain.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  10. Published

    In vivo Identification and Specificity assessment of mRNA markers of hypoxia in human and mouse tumors. / Busk, Morten; Toustrup, Kasper; Soerensen, Brita S; Alsner, Jan; Horsman, Michael R; Jakobsen, Steen; Overgaard, Jens.

    In: B M C Cancer, Vol. 11, No. 1, 09.02.2011, p. 63.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Effects of vagal nerve stimulation on noradrenaline receptor binding in minipigs by positron emission tomography. / Landau, Anne M.; Doudet, Doris; Alstrup, Aage Kristian Olsen; Jakobsen, Steen; Gjedde, Albert; Dyve, Suzan.

    2011. Abstract from Danish Epilepsy Meeting, Vejle, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  12. Published

    Long term decrease in alpha 2 receptor distribution volume after acute stimulation of NA release. / Doudet, Doris; Landau, Anne M.; Dyve, Suzan; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Gjedde, Albert.

    2011. Abstract from XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET, Barcelona, Spain.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  13. Published

    Imaging techniques in small and large animals. / Alstrup, Aage Kristian Olsen; Winterdahl, Michael; Simonsen, Mette; Jakobsen, Steen; Møller, Arne; Scheel-Krüger, Jørgen; Landau, Anne M.

    2011. Abstract from Scandlas Symposium, København, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  14. Published

    Electroconvulsive therapy alters dopamine and noradrenaline receptor binding in the göttingen minipig brain. / Landau, Anne M.; Alstrup, Aage Kristian Olsen; Møller, Arne; Simonsen, Mette; Jakobsen, Steen; Videbech, Poul; Wegener, Gregers; Gjedde, Albert; Doudet, Doris.

    2011. Abstract from World Molecular Imaging Congress (WMIC) , San Diego, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  15. Published

    On the interpretation of PET binding data in brain: Effects of anesthesia and consideration of species differences. / Alstrup, Aage Kristian Olsen; Landau, Anne M.; Holden, James E.; Simonsen, Mette; Schacht, Anna C.; Jakobsen, Steen; Wegener, Gregers; Hansen, Axel K.; Gjedde, Albert; Doudet, Doris.

    2011. Abstract from World Molecular Imaging Congress (WMIC), San Diego, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  16. Published

    Serotonergic modulation of receptor occupance in rats treated with L-DOPA after unilateral 6-OHDA lesioning. / Nahimi, Adjmal; Høltzermann, Mette; Landau, Anne M.; Simonsen, Mette; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Wang, Kim; Møller, Arne; Wegener, Gregers; Gjedde, Albert; Doudet, Doris.

    2011. Poster session presented at The Brain Prize Meeting, Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearch

  17. Published

    Elektrochok påvirker hjernens dopamin- og noradrenalin receptor-binding hos Göttingen minigrise. / Alstrup, Aage Kristian Olsen; Landau, Anne M.; Møller, Arne; Simonsen, Mette; Jakobsen, Steen; Audrain, Hélène; Videbech, Poul; Wegener, Gregers; Gjedde, Albert; Doudet, Doris.

    2011. Poster session presented at Psykiatriens Forskningsdag, .

    Research output: Contribution to conferencePosterResearch

  18. 2012
  19. Published

    Amphetamine challenge decreases yohimbine binding to α2 adrenoceptors in Landrace pig brain. / Landau, Anne M; Doudet, Doris J; Jakobsen, Steen.

    In: Psychopharmacology, Vol. 222, No. 1, 2012, p. 155-163.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Biodistribution and radiation dosimetry of [N-methyl-11C]mirtazapine, an antidepressant affecting adrenoceptors. / Marthi, Katalin; Hansen, Søren B; Jakobsen, Steen; Bender, Dirk; Smith, Stefan Bo; Smith, Donald F.

    In: Applied Radiation and Isotopes, Vol. 59, No. 2-3, 2012, p. 175-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Carbon-11 labelled cholylsarcosine: a PET-tracer for conjugated bile acids. / Frisch, Kim; Jakobsen, Steen; Sørensen, Michael; Munk, Ole Lajord; Alstrup, Aage Kristian Olsen; Ott, Peter; Hofmann, Alan F. ; Keiding, Susanne.

    2012. Poster session presented at Falk Symposium 184, XXII International Bile Acid Meeting, Wien, Austria.

    Research output: Contribution to conferencePosterResearchpeer-review

  22. Published

    Carbon-11 labelling of cholylsarcosine and in vivo imaging of conjugated bile acids by positron emission tomography. / Frisch, Kim; Jakobsen, Steen; Sørensen, Michael; Munk, Ole Lajord; Alstrup, Aage Kristian Olsen; Ott, Peter; Hofmann, Alan F.; Keiding, Susanne.

    2012. Poster session presented at Danish Chemical Society, Odense, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  23. Published

    Chronic L-DOPA treatment prevents increased binding of [11C] MDL100907 to 5-HT2A receptors in a rat model of Parkinson’s disease. / Nahimi, Adjmal; Landau, Annie; Høltzermann, Mette; Simonsen, Mette; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Gjedde, Albert; Doudet, Doris.

    2012. Poster session presented at The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain, Baltimore, United States.

    Research output: Contribution to conferencePosterResearchpeer-review

  24. Published

    Imaging Imidazoline-I2 Binding Sites in Porcine Brain Using 11C-BU99008. / Kealey, Steven; Turner, Emma M; Husbands, Stephen M; Salinas, Cristian A; Jakobsen, Steen; Tyacke, Robin J; Nutt, David J; Parker, Christine A; Gee, Antony D.

    In: Journal of Nuclear Medicine, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Inhibition plots of [11C]yohimbine binding reveal consistent non-displaceable volumes of distribution in multiple studies. / Landau, Annie; Dyve, Suzan; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Doudet, Doris; Gjedde, Albert.

    2012.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  26. Published

    Radiosynthesis and Characterization of 11C-GSK215083 as a PET Radioligand for the 5-HT6 Receptor. / Parker, Christine A; Gunn, Roger N; Rabiner, Eugenii A; Slifstein, Mark; Comley, Robert; Salinas, Cristian; Johnson, Christopher N; Jakobsen, Steen; Houle, Sylvain; Laruelle, Marc; Cunningham, Vincent J; Martarello, Laurent.

    In: Journal of Nuclear Medicine, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning. / Nahimi, Adjmal; Høltzermann, Mette; Landau, Anne M; Simonsen, Mette Kildevæld; Jakobsen, Steen; Alstrup, Aage Kristian Olsen; Vang, Kim; Møller, Arne; Wegener, Gregers; Gjedde, Albert; Doudet, Doris J.

    In: Journal of Neurochemistry, Vol. 120, No. 5, 2012, p. 806-817.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    [N-methyl-11C]cholylsarcosine, a novel bile acid tracer for PET/CT of hepatic excretory function : Radiosynthesis and proof-of-concept studies in pigs. / Frisch, Kim; Jakobsen, Steen; Sørensen, Michael; Munk, Ole Lajord; Alstrup, Aage K O; Ott, Peter; Hofmann, Alan F; Keiding, Susanne.

    In: Journal of Nuclear Medicine, Vol. 53, No. 5, 2012, p. 772-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review