Steen Jakobsen

PhD

Profile photo

Steen Jakobsen

  • Department of Clinical Medicine - Positron Emission Tomography Center
Postal address:
Nørrebrogade 44
8000
Aarhus C
Denmark

Email: steen@pet.auh.dk, steejako@rm.dk

Publications

Hepatic exposure of metformin in patients with non-alcoholic fatty liver disease

Sundelin, E. I. O., Gormsen, L. C., Heebøll, S., Vendelbo, M. H., Jakobsen, S., Munk, O. L., Feddersen, S., Brøsen, K., Hamilton-Dutoit, S. J., Pedersen, S. B., Grønbaek, H. & Jessen, N., 11 Apr 2019, In : British Journal of Clinical Pharmacology.

Biodistribution of [ 11C]-metformin and mRNA expression of placentae metformin transporters in the pregnant chinchilla

Dahl Andersen, M., Duvald, C. S., Vendelbo, M., Pedersen, S. B., Jakobsen, S., Alstrup, A. K. O., Mikkelsen, E., Ovesen, P. G. & Pedersen, M., 3 Apr 2019, (Accepted/In press) In : Contrast Media & Molecular Imaging (Print).

Visualization of intrathecal delivery by PET-imaging

Glud, A. N., Jakobsen, S., Landau, A., Alstrup, A. K. O. & Sorensen, J. C., 7 Feb 2019, In : Journal of Neuroscience Methods. 317, p. 45-48 4 p.

In vivo quantification of glial activation in minipigs overexpressing human alpha-synuclein

Lillethorup, T. P., Glud, A. N., Landeck, N., Alstrup, A. K. O., Jakobsen, S., Vang, K., Doudet, D. J., Brooks, D. J., Kirik, D., Hinz, R., Sorensen, J. C. & Landau, A. M., Dec 2018, In : Synapse. 72, 12, 12 p., 22060.

Metformin Targets Brown Adipose Tissue in vivo and Reduces Oxygen Consumption in vitro

Breining, P., Jensen, J. B., Sundelin, E. I., Gormsen, L. C., Jakobsen, S., Busk, M., Rolighed, L., Bross, P., Fernandez-Guerra, P., Markussen, L. K., Rasmussen, N. E., Hansen, J. B., Pedersen, S. B., Richelsen, B. & Jessen, N., Sep 2018, In : Diabetes, Obesity and Metabolism. 20, 9, p. 2264-2273

Publisher Correction: Hyperpolarized [1-C]-acetate Renal Metabolic Clearance Rate Mapping

Mikkelsen, E. F. R., Mariager, C. Ø., Nørlinger, T., Qi, H., Schulte, R. F., Jakobsen, S., Frøkiær, J., Pedersen, M., Stødkilde-Jørgensen, H. & Laustsen, C., 20 Jul 2018, In : Scientific Reports. 8, 1, p. 11235

Metformin does not Affect Postabsorptive Hepatic Free Fatty Acid Uptake, Oxidation or Resecretion in Humans: A 3-months Placebo Controlled Clinical Trial in Patients with Type 2 Diabetes and Healthy Controls

Gormsen, L. C., Søndergaard, E., Christensen, N. L., Jakobsen, S., Nielsen, E. H. T., Munk, O. L., Tolbod, L. P., Jessen, N. & Nielsen, S., Jun 2018, In : Diabetes, Obesity and Metabolism. 20, 6, p. 1435-1444

Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy

Landau, A. M., Alstrup, A. K. O., Audrain, H., Jakobsen, S., Simonsen, M., Møller, A., Videbech, P. B., Wegener, G., Gjedde, A. & Doudet, D. J., May 2018, In : Journal of Cerebral Blood Flow and Metabolism. 38, 5, p. 881-887 7 p.

Hyperpolarized [1-13C]-acetate Renal Metabolic Clearance Rate Mapping

Mikkelsen, E. F. R., Mariager, C. Ø., Nørlinger, T., Qi, H., Schulte, R. F., Jakobsen, S., Frøkiær, J., Pedersen, M., Stødkilde-Jørgensen, H. & Laustsen, C., 22 Nov 2017, In : Scientific Reports. 7, 1, p. 16002 9 p.

Radioligand binding analysis of α 2 adrenoceptors with [11C]yohimbine in brain in vivo: Extended Inhibition Plot correction for plasma protein binding

Phan, J-A., Landau, A. M., Jakobsen, S. & Gjedde, A., 22 Nov 2017, In : Scientific Reports. 7, 15979.

Genetic Polymorphisms in Organic Cation Transporter 1 Attenuates Hepatic Metformin Exposure in Humans

Sundelin, E., Gormsen, L. C., Jensen, J. B., Vendelbo, M. H., Jakobsen, S., Munk, O. L., Christensen, M. M. H., Brøsen, K., Frøkiaer, J. & Jessen, N., Nov 2017, In : Clinical Pharmacology and Therapeutics. 102, 5, p. 841-848

Hypoxia positron emission tomography imaging: combining information on perfusion and tracer retention to improve hypoxia specificity

Busk, M., Munk, O. L., Jakobsen, S. S. & Horsman, M. R., Nov 2017, In : Acta Oncologica. 56, 11, p. 1583-1590 8 p.

Whole-body biodistribution, dosimetry and metabolite correction of [11C]palmitate: A PET tracer for imaging of fatty acid metabolism

Christensen, N. L., Jakobsen, S., Schacht, A. C., Munk, O. L., Alstrup, A. K. O., Tolbod, L. P., Harms, H. J., Nielsen, S. & Gormsen, L. C., 26 Oct 2017, In : Molecular Imaging. 16

Radiosynthesis and evaluation of 1-substituted 3-(2,3-dihydro-1H-inden-2-yl)-6-(1-ethylpropyl)-(3R,6R)-2,5-piperazinedione derivatives as PET tracers for imaging the central oxytocinergic system

Marzano, C., Jakobsen, S., Salinas, C., Tang, S. P., Bender, D., Passchier, J. & Plisson, C., Oct 2017, In : Journal of Labelled Compounds and Radiopharmaceuticals. 60, 12, p. 556-565 10 p.

Results from (11)C-metformin-PET scans, tissue analysis and cellular drug-sensitivity assays questions the view that biguanides affects tumor respiration directly

Iversen, A. B., Horsman, M. R., Jakobsen, S., Jensen, J. B., Garm, C., Jessen, N., Breining, P., Frøkiær, J. & Busk, M., 25 Aug 2017, In : Scientific Reports. 7, 1, p. 9436 13 p., 9436.

Early synaptic dysfunction induced by α-synuclein in a rat model of Parkinson's disease

Phan, J-A., Stokholm, K., Zareba-Paslawska, J., Jakobsen, S., Vang, K., Gjedde, A., Landau, A. M. & Romero-Ramos, M., 25 Jul 2017, In : Scientific Reports. 7, 1, 6363.

FDG-PET reproducibility in tumor-bearing mice: comparing a traditional SUV approach with a tumor-to-brain tissue ratio approach

Busk, M., Munk, O. L., Jakobsen, S., Frøkiær, J., Overgaard, J. & Horsman, M. R., May 2017, In : Acta oncologica (Stockholm, Sweden). 56, 5, p. 706-712

Cholinergic PET imaging in infections and inflammation using 11C-donepezil and 18F-FEOBV

Jørgensen, N. P., Alstrup, A. K. O., Mortensen, F. V., Knudsen, K., Jakobsen, S., Madsen, L. B., Bender, D., Breining, P., Petersen, M. S., Schleimann, M. H., Dagnæs-Hansen, F., Gormsen, L. C. & Borghammer, P., Mar 2017, In : European Journal of Nuclear Medicine and Molecular Imaging. 44, 3, p. 449–458

In-vivo imaging of a2 adrenoceptors in Parkinson's disease with 11C-yohimbine

Nahimi, A., Kinnerup, M., Østergaard, K., Winterdahl, M., Fedorova, T. D., Jakobsen, S., Lund Schaldemose, J., Sommerauer, M. B., Borghammer, P. & Gjedde, A., 2017, In : European Journal of Neurology. 24, p. 594-595

Fast diffusion kurtosis imaging of fibrotic mouse kidneys

Kjølby, B. F., Khan, A. R., Chuhutin, A., Pedersen, L. H., Jensen, J. B., Jakobsen, S., Zeidler, D., Sangill, R., Nyengaard, J. R., Jespersen, S. N. & Hansen, B., 1 Dec 2016, In : NMR in Biomedicine. 29, 12, p. 1709 1719 p.

Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 &2 and AMP-activated Protein Kinase in the Kidney

Christensen, M., Jensen, J. B., Jakobsen, S., Jessen, N., Frøkiær, J., Kemp, B. E., Marciszyn, A. L., Li, H., Pastor-Soler, N. M., Hallows, K. R. & Nørregaard, R., 26 Oct 2016, In : Scientific Reports. 6, 14 p., 35952.

In Vivo Imaging of Human 11C-Metformin in Peripheral Organs: Dosimetry, Biodistribution and Kinetic Analyses

Gormsen, L. C., Sundelin, E. I., Jensen, J. B., Vendelbo, M. H., Jakobsen, S., Munk, O. L., Christensen, M. M. H., Brøsen, K., Frøkiær, J. & Jessen, N., 28 Jul 2016, In : The Journal of Nuclear Medicine.

Exogenous dopamine reduces GABA receptor availability in the human brain

Lou, H. O. C., Rosenstand, A., Brooks, D. J., Bender, D., Jakobsen, S., Blicher, J. U., Hansen, K. V. & Møller, A., Jul 2016, In : Brain and Behavior. 6, 7, p. e00484

[11C]-metformin distribution in the liver and small intestine using dynamic PET in mice demonstrates tissue-specific transporter dependency

Jensen, J. B., Sundelin, E. I., Jakobsen, S., Gormsen, L. C., Munk, O. L., Frøkiær, J. & Jessen, N., Jun 2016, In : Diabetes. p. 1724-1730

Renal PET-imaging with 11C-metformin in a transgenic mouse model for chronic kidney disease

Pedersen, L. H., Jensen, J. B., Wogensen, L., Munk, O. L., Jessen, N., Frøkiær, J. & Jakobsen, S., 20 May 2016, In : EJNMMI Research. 6, 7 p., 54.

Erratum to: Evaluation of ECG-gated [(11)C]acetate PET for measuring left ventricular volumes, mass, and myocardial external efficiency

Stubkjær Hansson, N. H., Tolbod, L., Harms, H. J., Wiggers, H., Kim, W. Y., Hansen, E., Zaremba, T., Frøkiær, J., Jakobsen, S. & Sørensen, J., 11 May 2016, In : Journal of Nuclear Cardiology. 23, 5, p. 1232-1232 1 p.

Molecular imaging of cholinergic processes in prostate cancer using (11)C-donepezil and (18)F-FEOBV

Stokholm, M. G., Høyer, S., Borre, M., Bender, D., Jakobsen, S., Frøkiær, J. & Borghammer, P., May 2016, In : European Journal of Nuclear Medicine and Molecular Imaging.

Automatic extraction of myocardial mass and volumes using parametric images from dynamic nongated PET

Harms, H. J., Hansson, N. H. S., Tolbod, L. P., Kim, W. Y., Jakobsen, S., Bouchelouche, K., Wiggers, H., Frøkiaer, J. & Sörensen, J., 28 Apr 2016, In : Journal of Nuclear Medicine. 57, 9, p. 1382-87 6 p.

Evaluation of ECG-gated [(11)C]acetate PET for measuring left ventricular volumes, mass, and myocardial external efficiency

Hansson, N. H., Tolbod, L., Harms, H., Wiggers, H., Kim, W. Y., Søvsø Szocska Hansen, E., Zaremba, T., Frøkiær, J., Jakobsen, S. & Sørensen, J., 19 Apr 2016, In : Journal of Nuclear Cardiology.

A PET Tracer for Renal Organic Cation Transporters, 11C-metformin: Radiosynthesis and Preclinical Proof-of-Concept Studies

Jakobsen, S., Busk, M., Jensen, J. B., Munk, O. L., Zois, N. E., Alstrup, A. K. O., Jessen, N. & Frøkiær, J., 1 Apr 2016, In : Journal of Nuclear Medicine. 57(4), p. 615-621

Neonatal domoic acid alters in vivo binding of [(11)C]yohimbine to α2-adrenoceptors in adult rat brain

Thomsen, M. B., Lillethorup, T. P., Jakobsen, S., Nielsen, E. H., Simonsen, M., Wegener, G., Landau, A. M. & Tasker, A., 2016, In : Psychopharmacology. 233, 21, p. 3779-3785

Neonatal domoic acid decreases in vivo binding of [11C]yohimbine to α2 adrenoceptors in adult rat brain

Thomsen, M., Lillethorup, T. P., Jakobsen, S., Nielsen, E. H. T., Simonsen, M., Wegener, G., Tasker, A. & Landau, A. M., Jul 2015.

Brain Serotonin Transporter Binding In a Minipig Model of Parkinson's Disease

Lillethorup, T. P., Glud, A. N., Sørensen, J. C. H., Landau, A. M., Jakobsen, S. & Jakobsen, S., 30 Jun 2015.

Neonatal domoic acid decreases in vivo binding of [11C]yohimbine to α2 adrenoceptors in adult rat brain

Thomsen, M., Lillethorup, T. P., Jakobsen, S., Nielsen, E. H. T., Simonsen, M., Wegener, G., Tasker, A. & Landau, A. M., Jun 2015.

Decreased in vivo α2 adrenoceptor binding in the Flinders Sensitive Line rat model of depression

Landau, A. M., Phan, J-A., Iversen, P., Lillethorup, T. P., Simonsen, M., Wegener, G., Jakobsen, S. & Doudet, D. J., Apr 2015, In : Neuropharmacology. 91, p. 97-102 6 p.

Mapping a2 Adrenoceptors of the Human Brain with 11C-Yohimbine

Nahimi, A., Jakobsen, S., Munk, O., Phan, J-A., Rodell, A. & Gjedde, A., Jan 2015, In : Journal of Nuclear Medicine.

Acute Vagal Nerve Stimulation Lowers α2 Adrenoceptor Availability: Possible Mechanism of Therapeutic Action

Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O., Gjedde, A. & Doudet, D., 2015, In : Brain Stimulation. 8, 4, p. 702-707 6 p.

Diffusion Kurtosis Imaging of Fibrotic Mouse Kidneys

Kjølby, B. F., Jakobsen, S., Jensen, J., Pedersen, L. H., Rydtoft, L. M., Jespersen, S. N. & Hansen, B., 2015.

Preclinical in-vivo imaging of activated NMDA receptor ion channels with the novel radioligand 18F-GE179

Vibholm, A. K., Landau, A. M., Winterdahl, M., Jakobsen, S., Alstrup, A. K. O., Simonsen, M., Bender, D., Møller, A., Pavese, N., Sørensen, J. C. H. & Brooks, D., 2015.

Quantification of [(11)C]yohimbine binding to α2 adrenoceptors in rat brain in vivo

Phan, J-A., Landau, A. M., Wong, D. F., Jakobsen, S., Nahimi, A., Doudet, D. J. & Gjedde, A., 2015, In : Journal of Cerebral Blood Flow and Metabolism. 35, 3, p. 501-511 11 p.

Minireview of Stereoselective Brain Imaging

Smith, D. F. & Jakobsen, S., 31 Dec 2014, In : Archives of Current Research International. 1, 1, p. 1-16 ACRI.2014.001.

Of Pig and Man: Analogy of response to electroconvulsive therapy (ECT): most do, a few don’t

Doudet, D. J., Clark, C., Alstrup, A. K. O., Jakobsen, S., Gjedde, A., Wegener, G., Videbech, P. & Landau, A. M., 22 Jun 2014.

Preclinical validation of 11C-Metformin: A novel PET tracer targeting organic cation transporters

Jakobsen, S., Busk, M., Munk, O. L., Alstrup, A. K. O., Gormsen, L. C., Jessen, N. & Frøkiær, J., 7 Jun 2014.

Phosphodiesterase 10A PET radioligand development program: from pig to human

Plisson, C., Weinzimmer, D., Jakobsen, S., Natesan, S., Salinas, C., Lin, S-F., Labaree, D., Zheng, M-Q., Nabulsi, N., Marques, T. R., Kapur, S., Kawanishi, E., Saijo, T., Gunn, R. N., Carson, R. E. & Rabiner, E. A., Apr 2014, In : Journal of Nuclear Medicine. 55, 4, p. 595-601 7 p.

In Vivo Imaging of Human Acetylcholinesterase Density in Peripheral Organs Using 11C-Donepezil: Dosimetry, Biodistribution, and Kinetic Analyses

Gjerløff, T., Jakobsen, S., Nahimi, A., Munk, O. L., Bender, D., Alstrup, A. K. O., Vase, K. H., Brooks, D. J. & Borghammer, P., 2014, In : Journal of Nuclear Medicine. 55, 11, p. 1818-24 7 p.

A model of Parkinson’s Disease in pig and primate by repeated intraventricular administration of an inhibitor of the ubiquitin proteasome system (UPS)

Doudet, D., Jakobsen, S., Alstrup, A. K. O., Møller, A., Sørensen, J. C. H. & Landau, A. M., 8 Dec 2013.

A model of Parkinson’s disease (PD) in pig and primate by repeated ICV administration of an inhibitor of the ubiquitin proteasome system (UPS)

Doudet, D., Jakobsen, S., Alstrup, A. K. O., Møller, A., Sørensen, J. C. H. & Landau, A. M., 8 Dec 2013.

Combined PET/microdialysis studies in minipig for PET tracer validation

Landau, A. M., Alstrup, A. K. O., Wegener, G., Jakobsen, S., Schacht, A. C., Jacobsen, J., Mørk, A., Sørensen, J. C. H. & Doudet, D., 18 Nov 2013.

Longitudinal in vivo imaging in a novel model of Parkinson’s disease in minipig

Landau, A. M., Jakobsen, S., Alstrup, A. K. O., Schacht, A. C., Winterdahl, M., Møller, A., Sørensen, J. C. H. & Doudet, D., 1 Oct 2013.

Effects of anesthesia and species on the uptake or binding of radioligands in vivo in the Göttingen minipig

Alstrup, A. K. O., Landau, A. M., Holden, J. E., Jakobsen, S., Schacht, A. C. S., Audrain, H., Wegener, G., Hansen, A. K., Gjedde, A. & Doudet, D., 15 Jul 2013, In : BioMed Research International. 2013, 808713, p. 1-9

Dose response in the binding of 11C-Yohimbine to alpha 2 adrenergic receptors in response to increasing doses of amphetamine

Doudet, D., Jakobsen, S., Alstrup, A. K. O. & Landau, A. M., 20 May 2013.

PET imaging of sugar addiction in minipigs: Effects on the dopamine D2/3 receptor

Landau, A. M., Møller, A., Winterdahl, M., Jakobsen, S., Alstrup, A. K. O., Schacht, A., Bender, D., Scheel-Krüger, J. & Kringelbach, M. L., 20 May 2013.

Proteasome inhibition model of Parkinson’s disease in Gottingen minipig: Combined dopaminergic and noradrenergic effects

Landau, A. M., Jakobsen, S., Alstrup, A. K. O., Schacht, A. C., Møller, A., Sørensen, J. C. H. & Doudet, D., 20 May 2013.

PET Imaging Sugar Addiction in Minipigs

Landau, A. M., Møller, A., Winterdahl, M., Alstrup, A. K. O., Jakobsen, S., Schacht, A. C., Bender, D., Scheel-Krüger, J. & Kringelbach, M. L., 3 May 2013.

Differential Amphetamine and Ligand Concentration Inhibition of 11C-Yohimbine binding in Brain: Effect of Plasma Protein Binding Displacement.

Phan, J-A., Landau, A. M., Jakobsen, S., Doudet, D. & Gjedde, A., May 2013.

PET hypoxia imaging with FAZA: reproducibility at baseline and during fractionated radiotherapy in tumour-bearing mice

Busk, M., Mortensen, L. S., Nordsmark, M., Overgaard, J., Jakobsen, S., Hansen, K. V., Theil, J., Kallehauge, J., D'Andrea, F. P., Steiniche, T. & Horsman, M. R., Jan 2013, In : European Journal of Nuclear Medicine and Molecular Imaging. 40, 2, p. 186-97 12 p.

Molecular Neurobiology of Depression: PET Findings on the Elusive Correlation with Symptom Severity

Smith, D. F. & Jakobsen, S., 2013, In : Frontiers in Psychiatry. 4, p. 8

PET imaging of tumor hypoxia using 18F-labeled pimonidazole

Busk, M., Jakobsen, S., Horsman, M. R., Mortensen, L. S., Iversen, A. B., Overgaard, J., Nordsmark, M., Ji, X., Lee, D. Y. & Raleigh, J. R., 2013, In : Acta Oncologica. 52, 7, p. 1300-1307 8 p.

In vivo alpha2-adrenoceptor-binding viser en forlænget effekt af elektrochok-behandling på den noradrenerge funktion i Göttingen minigrise

Landau, A., Wegener, G., Alstrup, A. K. O., Jakobsen, S., Audrain, H., Møller, A., Simonsen, M., Gjedde, A., Videbech, P. & Doudet, D., 8 Nov 2012.

Kombineret in vivo PET-mikrodialyse studier af noradrenalin frisættelse i minigrise

Landau, A. M., Wegener, G., Jakobsen, S., Schacht, A. C., Alstrup, A. K. O., Jacobsen, J., Mørk, A., Sørensen, J. C. H. & Doudet, D., 8 Nov 2012.

FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: Results from the DAHANCA 24 trial

Mortensen, L. S., Johansen, J., Kallehauge, J. F., Primdahl, H., Busk, M., Lassen, P., Alsner, J., Sørensen, B. S., Toustrup, K., Jakobsen, S., Petersen, J., Petersen, H., Theil, J., Nordsmark, M. & Overgaard, J., Oct 2012, In : Radiotherapy & Oncology. 105, 1, p. 14-20 7 p.

Evaluating NA release with C-11 yohimbine: combined in vivo PET-microdialysis studies

Doudet, D., Wegener, G., Jakobsen, S., Alstrup, A. K. O., Mørk, A., Sørensen, J. C. H. & Landau, A. M., 9 Aug 2012.

Update: inhibition plots of [C-11]yohimbine binding yield consistent estimates of non-displaceable volumes of distribution in multiple tests

Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O., Doudet, D. & Gjedde, A., 9 Aug 2012.

Amphetamine-induced inhibition of [C-11]yohimbine binding in rat brain

Phan, J-A., Jakobsen, S., Landau, A. M., Doudet, D. & Gjedde, A., Aug 2012.

Displacement of [11C]yohimbine binding in brain reveals noradrenaline release by vagal nerve stimulation

Landau, A., Dyve, S., Jakobsen, S., Alstrup, A. K. O., Møller, A., Doudet, D. & Gjedde, A., 7 Jun 2012.

Combined in vivo PET-microdialysis studies of NA release in minipig

Doudet, D., Landau, A., Jakobsen, S., Alstrup, A. K. O., Mørk, A., Sørensen, J. C. H. & Wegener, G., 3 Jun 2012.

In vivo alpha2 adrenoceptor binding demonstrates a prolonged effect of electroconvulsive therapy on noradrenergic function in Gottingen minipigs

Landau, A., Wegener, G., Alstrup, A. K. O., Jakobsen, S., Audrain, H., Møller, A., Simonsen, M., Gjedde, A., Videbech, P. & Doudet, D., 3 Jun 2012.

Amphetamine challenge decreases yohimbine binding to α2 adrenoceptors in Landrace pig brain

Landau, A. M., Doudet, D. J. & Jakobsen, S., 2012, In : Psychopharmacology. 222, 1, p. 155-163

Biodistribution and radiation dosimetry of [N-methyl-11C]mirtazapine, an antidepressant affecting adrenoceptors

Marthi, K., Hansen, S. B., Jakobsen, S., Bender, D., Smith, S. B. & Smith, D. F., 2012, In : Applied Radiation and Isotopes. 59, 2-3, p. 175-9 5 p.

Carbon-11 labelled cholylsarcosine: a PET-tracer for conjugated bile acids

Frisch, K., Jakobsen, S., Sørensen, M., Munk, O. L., Alstrup, A. K. O., Ott, P., Hofmann, A. F. & Keiding, S., 2012.

Carbon-11 labelling of cholylsarcosine and in vivo imaging of conjugated bile acids by positron emission tomography

Frisch, K., Jakobsen, S., Sørensen, M., Munk, O. L., Alstrup, A. K. O., Ott, P., Hofmann, A. F. & Keiding, S., 2012.

Chronic L-DOPA treatment prevents increased binding of [11C] MDL100907 to 5-HT2A receptors in a rat model of Parkinson’s disease

Nahimi, A., Landau, A., Høltzermann, M., Simonsen, M., Jakobsen, S., Alstrup, A. K. O., Gjedde, A. & Doudet, D., 2012.

Imaging Imidazoline-I2 Binding Sites in Porcine Brain Using 11C-BU99008

Kealey, S., Turner, E. M., Husbands, S. M., Salinas, C. A., Jakobsen, S., Tyacke, R. J., Nutt, D. J., Parker, C. A. & Gee, A. D., 2012, In : Journal of Nuclear Medicine.

Inhibition plots of [11C]yohimbine binding reveal consistent non-displaceable volumes of distribution in multiple studies

Landau, A., Dyve, S., Jakobsen, S., Alstrup, A. K. O., Doudet, D. & Gjedde, A., 2012.

Radiosynthesis and Characterization of 11C-GSK215083 as a PET Radioligand for the 5-HT6 Receptor

Parker, C. A., Gunn, R. N., Rabiner, E. A., Slifstein, M., Comley, R., Salinas, C., Johnson, C. N., Jakobsen, S., Houle, S., Laruelle, M., Cunningham, V. J. & Martarello, L., 2012, In : Journal of Nuclear Medicine.

Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning

Nahimi, A., Høltzermann, M., Landau, A. M., Simonsen, M. K., Jakobsen, S., Alstrup, A. K. O., Vang, K., Møller, A., Wegener, G., Gjedde, A. & Doudet, D. J., 2012, In : Journal of Neurochemistry. 120, 5, p. 806-817

[N-methyl-11C]cholylsarcosine, a novel bile acid tracer for PET/CT of hepatic excretory function: Radiosynthesis and proof-of-concept studies in pigs

Frisch, K., Jakobsen, S., Sørensen, M., Munk, O. L., Alstrup, A. K. O., Ott, P., Hofmann, A. F. & Keiding, S., 2012, In : Journal of Nuclear Medicine. 53, 5, p. 772-8 7 p.

Elektrochok påvirker hjernens dopamin- og noradrenalin receptor-binding hos Göttingen minigrise

Alstrup, A. K. O., Landau, A. M., Møller, A., Simonsen, M., Jakobsen, S., Audrain, H., Videbech, P., Wegener, G., Gjedde, A. & Doudet, D., 17 Nov 2011.

Serotonergic modulation of receptor occupance in rats treated with L-DOPA after unilateral 6-OHDA lesioning

Nahimi, A., Høltzermann, M., Landau, A. M., Simonsen, M., Jakobsen, S., Alstrup, A. K. O., Wang, K., Møller, A., Wegener, G., Gjedde, A. & Doudet, D., 7 Oct 2011.

Electroconvulsive therapy alters dopamine and noradrenaline receptor binding in the göttingen minipig brain

Landau, A. M., Alstrup, A. K. O., Møller, A., Simonsen, M., Jakobsen, S., Videbech, P., Wegener, G., Gjedde, A. & Doudet, D., 7 Sep 2011.

On the interpretation of PET binding data in brain: Effects of anesthesia and consideration of species differences

Alstrup, A. K. O., Landau, A. M., Holden, J. E., Simonsen, M., Schacht, A. C., Jakobsen, S., Wegener, G., Hansen, A. K., Gjedde, A. & Doudet, D., 7 Sep 2011.

Imaging techniques in small and large animals

Alstrup, A. K. O., Winterdahl, M., Simonsen, M., Jakobsen, S., Møller, A., Scheel-Krüger, J. & Landau, A. M., 25 May 2011. 1 p.

Long term decrease in alpha 2 receptor distribution volume after acute stimulation of NA release

Doudet, D., Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O. & Gjedde, A., 24 May 2011.

Effects of vagal nerve stimulation on noradrenaline receptor binding in minipigs by positron emission tomography

Landau, A. M., Doudet, D., Alstrup, A. K. O., Jakobsen, S., Gjedde, A. & Dyve, S., 11 Mar 2011.

In vivo Identification and Specificity assessment of mRNA markers of hypoxia in human and mouse tumors

Busk, M., Toustrup, K., Soerensen, B. S., Alsner, J., Horsman, M. R., Jakobsen, S. & Overgaard, J., 9 Feb 2011, In : B M C Cancer. 11, 1, p. 63

Accessing radiation response using hypoxia PET imaging and oxygen sensitive electrodes: a preclinical study

Mortensen, L. S., Busk, M., Nordsmark, M., Jakobsen, S., Theil, J., Overgaard, J. & Horsman, M. R., 2011, In : Radiotherapy & Oncology. 99, 3, p. 418-23 6 p.

Inhibition of tumor lactate oxidation: consequences for the tumor microenvironment

Busk, M., Walenta, S., Mueller-Klieser, W., Steiniche, T., Jakobsen, S., Horsman, M. R. & Overgaard, J., 2011, In : Radiotherapy & Oncology. p. 404-11 8 p.

PET imaging of patients with non-small cell lung cancer employing an EGF receptor targeting drug as tracer

Memon, A. A., Weber, B., Winterdahl, M., Jakobsen, S., Meldgaard, P., Madsen, H. H. T., Keiding, S., Nexo, E. & Sorensen, B. S., 2011, In : B J C. 105, 12, p. 1850-5 6 p.

Radiosynthesis and in vivo evaluation of [(11)C]MP-10 as a positron emission tomography radioligand for phosphodiesterase 10A

Plisson, C., Salinas, C., Weinzimmer, D., Labaree, D., Lin, S-F., Ding, Y-S., Jakobsen, S., Smith, P. W., Eiji, K., Carson, R. E., Gunn, R. N. & Rabiner, E. A., 2011, In : Nuclear Medicine and Biology. 38, 6, p. 875-84 10 p.

The minipig as an animal model to study antidepressant pharmacology by PET

Landau, A. M., Dyve, S., Alstrup, A. K. O., Jakobsen, S., Simonsen, M., Møller, A., Videbech, P., Wegener, G., Gjedde, A. & Doudet, D., 2011.

Tracer kinetic responses to propofol-induced reduction of brain perfusion: Comparison of [11C]Yohimbine and [11C]SCH23390

Holden, J. E., Jakobsen, S., Alstrup, A. K. O., Doudet, D. & Landau, A. M., 2011.

Acute vagal nerve stimulation promotes noradrenaline release in minipig brain

Landau, A. M., Dyve, S., Alstrup, A. K. O., Jakobsen, S., Rodell, A., Gjedde, A. & Doudet, D., 2010.

Anesthesia in animal imaging: Differing effects of propofol versus isoflurane on dopamine 1 receptor binding in Göttingen minipig brain

Alstrup, A. K. O., Jakobsen, S., Wegener, G., Hansen, A. K., Doudet, D. & Landau, A. M., 2010, In : NeuroImage. 1, p. 181

Assessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET

Busk, M., Munk, O. L., Jakobsen, S., Wang, T., Skals, M., Steiniche, T., Horsman, M. R. & Overgaard, J., 2010, In : Acta Oncologica. 49, 7, p. 922-33 11 p.

Electroconvulsive therapy alters monoamine receptor binding in the brain of Göttingen minipigs: mechanistic clues into antidepressant action

Landau, A. M., Alstrup, A. K. O., Møller, A., Simonsen, M., Jakobsen, S., Videbech, P., Wegener, G., Gjedde, A. & Doudet, D., 2010.

Identification and evaluation of [11C]GSK931145 as a novel ligand for imaging the type 1 glycine transporter with positron emission tomography

Passchier, J., Gentile, G., Porter, R., Herdon, H., Salinas, C., Jakobsen, S., Audrain, H., Laruelle, M. & Gunn, R. N., 2010, In : Synapse. 64, 7, p. 542-9 8 p.

Kinetic of Yohimbine binding in porcine brain in vivo

Gjedde, A., Rodell, A., Jakobsen, S., Alstrup, A. K. O., Møller, A., Dyve, S., Landau, A. M. & Doudet, D., 2010, In : NeuroImage. 1, p. 225

Noradrenaline release explains effects of vagal nerve stimulation in pig brain in vivo. PET study with tracer [11C]yohimbine, an alpha 2 adrenoceptor antagonist

Dyve, S., Landau, A. M., Alstrup, A. K. O., Jakobsen, S., Doudet, D. & Gjedde, A., 2010.

Noradrenaline release: a potential antidepressant mechanism of brain stimulation therapies

Landau, A. M., Dyve, S., Alstrup, A. K. O., Møller, A., Simonsen, M., Jakobsen, S., Videbech, P., Wegener, G. & Doudet, D., 2010.

Noradrenaline release: potential antidepressant mechanism of brain stimulation

Doudet, D., Dyve, S., Alstrup, A. K. O., Jakobsen, S., Simonsen, M., Møller, A., Videbech, P., Wegener, G., Gjedde, A. & Landau, A. M., 2010, In : NeuroImage. 1, p. 47

Noradrenaline release: potential antidepressant mechanism of brain stimulation?

Doudet, D., Dyve, S., Olsen Alstrup, A. K., Jakobsen, S., Simonsen, M., Møller, A., Videbech, P., Wegener, G., Gjedde, A. & Landau, A. M., 2010, In : NeuroImage.

Synthesis and in vivo evaluation of [11C]BU99008 as a ligand for the imidazoline I2 binding site

Kealey, S., Husbands, S., Casey, E. M., Salinas, C. A., Parker, C. A., Jakobsen, S., Tyacke, R. J., Nutt, D. J. & Gee, A. D., 2010, In : NeuroImage. 52, Supplement 1, 0, p. S127 - S128

Can hypoxia-PET map hypoxic cell density heterogeneity accurately in an animal tumor model at a clinically obtainable image contrast?

Busk, M., Horsman, M. R., Jakobsen, S., Hansen, K. V., Bussink, J., van der Kogel, A. & Overgaard, J., Sep 2009, In : Radiotherapy & Oncology. 92, 3, p. 429-436 7 p.

Dopamine D3 receptor antagonists: the quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in vivo studies

Bennacef, I., Salinas, C. A., Bonasera, T. A., Gunn, R. N., Audrain, H., Jakobsen, S., Nabulsi, N., Weinzimmer, D., Carson, R. E., Huang, Y., Holmes, I., Micheli, F., Heidbreder, C., Gentile, G., Rossi, T. & Laruelle, M., 2009, In : Bioorganic & Medicinal Chemistry Letters. 19, 17, p. 5056-9 4 p.

Electroconvulsive therapy induces alterations in monoaminergic receptor binding in the striatum and frontal cortex of healthy minipigs

Landau, A. M., Alstrup, A. K. O., Møller, A., Jakobsen, S., Wegener, G., Videbech, P., Vang, K., Gjedde, A. & Doudet, D., 2009.

Molecular tools for assessing human depression by positron emission tomography

Smith, D. F. & Jakobsen, S., 2009, In : European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 19, 9, p. 611-28 17 p.

Positron emission tomography (PET) imaging with [11C]-labeled erlotinib: a micro-PET study on mice with lung tumor xenografts

Memon, A. A., Jakobsen, S., Dagnaes-Hansen, F., Sørensen, B. S., Keiding, S. & Nexø, E., 2009, In : Cancer research. 69, 3, p. 873-8 5 p.

[(11)C]Mirtazapine binding in depressed antidepressant nonresponders studied by PET neuroimaging

Smith, D., Stork, B., Wegener, G., Ashkanian, M., Jakobsen, S., Bender, D., Audrain, H., Vase, K., Videbech, P. & Rosenberg, R., 2009, In : Psychopharmacology. 206, p. 133-140

[11C] labeled erlotinib as a new radiotracer for identification of patients responding to erlotinib treatment: A preliminary study on lung cancer patients

Memon, A. A., Weber, B., Jakobsen, S., Winterdahl, M., Dagnæs-Hansen, F., Madsen, H. H. T., Meldgaard, P., Sørensen, B. S., Keiding, S. & Nexø, E., 2009, In : Journal of Thoracic Oncology. 9, p. S698

Cellular uptake of PET tracers of glucose metabolism and hypoxia and their linkage

Busk, M., Horsman, M. R., Jakobsen, S., Bussink, J., van der Kogel, A. & Overgaard, J., Dec 2008, In : European Journal of Nuclear Medicine and Molecular Imaging. 35, 12, p. 2294-303 10 p.

Imaging Hypoxia in Xenografted and Murine Tumors with 18F-Fluoroazomycin Arabinoside: A Comparative Study Involving microPET, Autoradiography, pO2-Polarography, and Fluorescence Microscopy

Busk, M., Horsman, M. R., Jakobsen, S., Keiding, S., van der Kogel, A. J., Bussink, J. & Overgaard, J., 15 Mar 2008, In : International Journal of Radiation: Oncology - Biology - Physics. 70, 4, p. 1202-12 11 p.

Neuroimaging of mirtazapine enantiomers in humans.

Smith, D., Hansen, S., Jakobsen, S., Bender, D., Audrain, H., Ashkanian, M., Stork, B., Minuzzi, L., Hall, H. & Rosenberg, R., 2008, In : Psychopharmacology. 200, p. 273-279 7 p.

Novel synthesis and evaluation of 11C Corynanthine as alpha-1 adrenergic tracer

Jakobsen, S., Olsen, A. K. & Nahimi, A., 2008.

Regional binding potentials of [11C]mirtazapine enantiomers in human brain

Smith, D. F., Hansen, S. B., Jakobsen, S., Bender, D., Audrain, H., Ashkanian, M., Stork, B. S. & Rosenberg, R., 2008, In : European Neuropsychopharmacology. 18, S4, p. S260-S261

Receptor occupancy of mirtazapine determined by PET in healthy volunteers

Smith, D. F., Stork, B. S., Wegener, G., Jakobsen, S., Bender, D., Audrain, H., Jensen, S. B., Hansen, S. B., Rodell, A. & Rosenberg, R., 1 Nov 2007, In : Psychopharmacology. 195, 1, p. 131-138 8 p.

A PET study of effects of chronic 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on serotonin markers in Göttingen minipig brain.

Cumming, P., Møller, M., Benda, K., Minuzzi, L., Jakobsen, S., Jensen, S. B., Pakkenberg, B., Stark, A. K., Gramsbergen, J. B., Andreasen, M. F. & Olsen, A. K., 2007, In : Synapse. 61, 7, p. 478-87 9 p.

Parametric and regional maps of free serotonin 5HT1A receptor sites in human brain as function of age in healthy humans.

Møller, M., Jakobsen, S. & Gjedde, A., 2007, In : Neuropsychopharmacology. 32, 8, p. 1707-14 7 p.

Receptor occupancy of mirtazapine determined by PET in healty volunteers

Smith, D. F., Stork, B. S., Wegener, G., Jakobsen, S., Bender, D., Audrain, H., Jensen, S. B., Hansen, S. B., Rodell, A. & Rosenberg, R., 2007, In : Psychopharmacology.

Role of monoaminergic innervation in 6-hydroxydopamine unilateral lesioned animal model of Parkinsons Disease and L-DOPA induced dyskinesia

Nahimi, A., Olsen, A. K., Møller, A., Jakobsen, S., Østergaard, S. D. & Doudet, D., 2007.

Stereoselective neuroimaging in vivo

Smith, D. F. & Jakobsen, S., 2007, In : European Neuropsychopharmacology.

Inhibition of [11C]mirtazapine binding by alpha2-adrenoceptor antagonists studied by positron emission tomography in living porcine brain

Smith, D. F., Dyve, S., Minuzzi, L., Jakobsen, S., Munk, O. L., Marthi, K. & Cumming, P., 15 Jun 2006, In : Synapse. 59, 8, p. 463-71 9 p.

Binding of the hallucinogen 5-[11C] Meo-DMT in brain of living pigs

Pedersen, K., Gjedde, A., Olsen, A. K., Jakobsen, S., Cumming, P. & Jensen, S. B., 2006.

Binding of the hallucinogen MeO-DMT in the brain of domestic pig

Olsen, A. K., Jensen, S. B., Pedersen, K., Jakobsen, S. & Cumming, P., 2006.

Characterisation of the binding of the hallucinogen 11C-MEO-DMT in brain of living pigs

Jensen, S. B., Olsen, A. K., Pedersen, K., Jakobsen, S. & Cumming, P., 2006, In : Journal of Nuclear Medicine. p. 278P

Detection of alpha2-adrenergic receptors in brain of living pig with 11C-yohimbine

Jakobsen, S., Pedersen, K., Smith, D. F., Jensen, S. B., Munk, O. L. & Cumming, P., 2006, In : J. Nucl. Med.. 47, p. 2008-2015 7 p.

Detection of alphe-2 adrenergic receptora in brain of living pig with [11C]yohimbine

Jakobsen, S., Pedersen, K., Smith, D. F., Jensen, S. B., Olsen, A. K. & Cumming, P., 2006, In : NeuroImage. p. T123-T124

Detection of {alpha}2-Adrenergic Receptors in Brain of Living Pig with 11C-Yohimbine

Jakobsen, S., Pedersen, K., Smith, D. F., Jensen, S. B., Munk, O. L. & Cumming, P., 2006, In : The Journal of Nuclear Medicine. 47, 12, p. 2008-2015

Inhibition of [(11)C]mirtazapine binding by alpha(2)-adrenoceptor antagonists studied by positron emission tomography in living porcine brain

Smith, D. F., Dyve, S., Minuzzi, L., Jakobsen, S., Munk, O. L., Marthi, K. & Cumming, P., 2006, In : Synapse. 59, 8, p. 463-471

Mapping of the hallucinogen 5-Meo-DMT in living pig brain

Pedersen, K., Olsen, A. K., Jakobsen, S., Gjedde, A., Cumming, P. & Jensen, S. B., 2006.

Mapping of the hallucinogen 5-Meo-DMT in living porcine brain

Pedersen, K., olsen, A. K., Jakobsen, S., Gjedde, A., Cumming, P. & Jensen, S. B., 2006.

PET neuroimaging of [11C]mirtazapine enantiomers in pigs

Smith, D. F., Marthi, K., Munk, O. L., Cumming, P., Hansen, S. B. & Jakobsen, S., 2006, In : European Neuropsychopharmacology. 16, 5, p. 350-7 8 p.

Synthesis, radiolabeling and in vivo evaluation of [11C]RAL-01, a potential phosphodiesterase 5 radioligand

Jakobsen, S., Kodahl, G. M., Olsen, A. K. & Cumming, P., 2006, In : Nucl. Med. Biol.. 33, p. 593-597 4 p.

[11C]Yohimbine as a PET radioligand for visualising the adrenergic receptors at work

Jakobsen, S., Smith, D. F., Jensen, S. B., Olsen, A. K., Pedersen, K. & Cumming, P., 2006, In : European Journal of Nuclear Medicine and Molecular Imaging. p. S212

A dose-response study of ecstasy (MDMA) on the porcine serotonin system

Olsen, A. K., Jakobsen, S., Jensen, S. B., Minuzzi, L. & Cumming, P., 2005.

Behavioral response to novelty correlates with dopamine receptor availability in striatum of Göttingen minipigs.

Lind, N. M., Gjedde, A., Moustgaard, A., Olsen, A. K., Jensen, S. B., Jakobsen, S., Arnfred, S. M., Hansen, A. K., Hemmingsen, R. P. & Cumming, P., 2005, In : Behavioural Brain Research. 164, 2, p. 172-7 5 p.

Behaviour of [11C]R(-)- and [11C]S(+)-rolipram in vitro and in vivo, and their use as PET radiotracers for the quantificative assay of PDE4

Parker, C. A., Matthews, J. C., Gunn, R. N., Martarello, L., Cunningham, V. J., Dommett, D., Knibb, S. T., Bender, D., Jakobsen, S., Brown, J. & Gee, A. D., 2005, In : Synapse. 55, 4, p. 270-9 10 p.

Mapping the amphetamine-evoked dopamine release in the brain of the Göttingen minipig.

Lind, N. M., Olsen, A. K., Moustgaard, A., Jensen, S. B., Jakobsen, S., Hansen, A. K., Arnfred, S. M., Hemmingsen, R. P., Gjedde, A. & Cumming, P., 2005, In : Brain Research Bulletin. 65, 1, p. 1-9 8 p.

Response to novel correlates with dopamine receptor availability in striatum of living pigs

Lind, N. M., Moustgaard, A., Olsen, A. K., Jensen, S. B., Jakobsen, S., Hansen, A. K., Arnfred, S. M., Hemmingsen, R. P., Gjedde, A. & Cumming, P., 2005, In : Schizophrenia Bulletin. p. 304

Response to novel correlates with dopamine receptor availability in striatum of living pigs

Lind, N. M., Moustgaard, A., Olsen, A. K., Jensen, S. B., Jakobsen, S., Hansen, A. K., Arnfred, S. M., Hemmingsen, R. P., Gjedde, A. & Cumming, P., 2005, In : Molecular Imaging and Biology. p. 142

Synthesis, radiolabeling and in vivo evaluation of [11C]RAL-01 as potential phospordiesterase PET radioligand in the pig

Jakobsen, S., Kodahl, G., Cumming, P. & Olsen, A. K., 2005.

The dose-response effect of MDMA ("Ecstasy") treatment on the serotonin system in the porcine brain

Olsen, A. K., Jakobsen, S., Jensen, S. B., Minuzzi, L. & Cumming, P., 2005.

[N-methyl-11C]Mirtazapine for positron emission tomography neuroimaging of antidepressant actions in humans

Marthi, K., Jakobsen, S., Bender, D., Hansen, S. B., Smith, S. B., Hermansen, F., Rosenberg, R. & Smith, D. F., 2004, In : Psychopharmacology. 174, 2, p. 260-5 6 p.

Projects

Defining the Role of Organic Cation Transporters in Diabetes Treatment 5.000.000 DKK - Novo Nordisk Fonden

Jessen, N., Frøkiær, J., Jakobsen, S., Ørntoft, T. F., Brøsen, K. & Grønbæk, H.

Novo Nordisk Fonden

01/05/201330/04/2018

Development of new PET ligands for imaging the parasympathetic nervous system

Borghammer, P., Jakobsen, S., Gjerløff, T., Bender, D. & Brooks, D.

Lundbeckfonden, Forskningsstyrelsen for Sundhed og Sygdom

01/12/201230/04/2016

Effects of ECT on monoaminergic transmission in a genetic rat model of depression 20.000 DKK - Lily Benthine Lunds fond af 1.6.1978

Landau, A., Jakobsen, S., Iversen, P., Simonsen, M., Doudet, D., Wegener, G., Alstrup, A. K. O. & Schacht, A.

Lily Benthine Lunds fond af 1.6.1978

01/01/2010 → …

Effects of electroconvulsive therapy on brain monoaminergic systems 1.963.200 DKK - Danish Medical Research Council

Landau, A., Jakobsen, S., Alstrup, A. K. O., Doudet, D., Wegener, G., Videbech, P., Møller, A., Audrain, H. & Gjedde, A.

Danish Medical Research Council

01/09/2009 → …

Evaluating noradrenaline release in vivo by PET 1.500.000 - Lundbeckfonden

Doudet, D., Jakobsen, S., Alstrup, A. K. O., Landau, A., Wegener, G., Sørensen, J. C. H. & Jacobsen, J.

Lundbeckfonden

01/01/2011 → …

IN-VIVO IMAGING OF NOREPINEPHRINE IN PARKINSON ́S DISEASE AND L-DOPA INDUCED DYSKINESIA 1.200.000 DKK - Lundbeck fonden

Gjedde, A., Jakobsen, S., Nahimi, A., Bender, D., Borghammer, P. & Østergaard, K.

Lundbeck Fonden

01/01/2012 → …

YOYO: Imaging of the adrenergic alpha2 receptors in the human brain with yohimbine after amphetamine challenge 109.685 DKK - Riisfort fonden

Jakobsen, S., Borghammer, P., Munk, O. L., Hansen, K. V. & Nahimi, A.

01/02/2012 → …

Imaging the obesity epidemic: Cortical prosessing of wanting, liking and homeostatic regulation in minipigs 500.000 DKK - AU IDEAS

Landau, A., Jakobsen, S., Bender, D., Møller, A., Kringelbach, M. L., Scheel-Krüger, J. & Alstrup, A. K. O.

AU IDEAS

01/01/2012 → …

Monoaminergic mechanisms of the therapeutic effects of VNS1.000.000 DKK - Lundbeck fonden

Doudet, D., Landau, A., Jakobsen, S., Alstrup, A. K. O., Dyve, S. & Gjedde, A.

Lundbeck fonden

01/06/2009 → …

Novel porcine method paper- confidential

GLUD, A., Jakobsen, S., Landau, A., Frøkiær, J., Alstrup, A. K. O. & Sørensen, J. C. H.

26/04/201511/02/2019

Validation of a novel progressive model of Parkinson’s disease in minipig 290.000 DKK - Parkinsonforeningen

Landau, A., Jakobsen, S., Alstrup, A. K. O., Doudet, D., Sørensen, J. C. H. & Møller, A.

Parkinsonforeningen

01/01/2012 → …