Sofie Eg Jørgensen

  1. 2021
  2. E-pub ahead of print

    Postpartum disseminated HSV-1 infection with hemophagocytic lymphohistiocytosis and fulminant neonatal herpes infection. / Freytag, Mette Ratzer; Jørgensen, Sofie Eg; Thomsen, Michelle Mølgaard; Al-Mousawi, Ali; Hait, Alon Schneider; Olagnier, David; Bay, Jakob T; Helleberg, Marie; Mogensen, Trine H.

    In: The Journal of Infectious Diseases, 26.05.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    STK4 Deficiency Impairs Innate Immunity and Interferon Production Through Negative Regulation of TBK1-IRF3 Signaling. / Jørgensen, Sofie E.; Al-Mousawi, Ali; Assing, Kristian; Hartling, Ulla; Grosen, Dorthe; Fisker, Niels; Nielsen, Christian; Jakobsen, Marianne A.; Mogensen, Trine H.

    In: Journal of Clinical Immunology, Vol. 41, No. 1, 01.2021, p. 109–124.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. 2020
  5. Published

    Author Correction : SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate. / Olagnier, David; Farahani, Ensieh; Thyrsted, Jacob; Blay-Cadanet, Julia; Herengt, Angela; Idorn, Manja; Hait, Alon; Hernaez, Bruno; Knudsen, Alice; Iversen, Marie Beck; Schilling, Mirjam; Jørgensen, Sofie E; Thomsen, Michelle; Reinert, Line S; Lappe, Michael; Hoang, Huy-Dung; Gilchrist, Victoria H; Hansen, Anne Louise; Ottosen, Rasmus; Nielsen, Camilla G; Møller, Charlotte; van der Horst, Demi; Peri, Suraj; Balachandran, Siddharth; Huang, Jinrong; Jakobsen, Martin; Svenningsen, Esben B; Poulsen, Thomas B; Bartsch, Lydia; Thielke, Anne L; Luo, Yonglun; Alain, Tommy; Rehwinkel, Jan; Alcamí, Antonio; Hiscott, John; Mogensen, Trine H; Paludan, Søren R; Holm, Christian K.

    In: Nature Communications, Vol. 11, No. 1, 5419, 21.10.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperComment/debate/letter to the editorResearchpeer-review

  6. Published

    SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate. / Olagnier, David; Farahani, Ensieh; Thyrsted, Jacob; Blay-Cadanet, Julia; Herengt, Angela; Idorn, Manja; Hait, Alon; Hernaez, Bruno; Knudsen, Alice; Iversen, Marie Beck; Schilling, Mirjam; Jørgensen, Sofie E; Thomsen, Michelle; Reinert, Line S; Lappe, Michael; Hoang, Huy-Dung; Gilchrist, Victoria H; Hansen, Anne Louise; Ottosen, Rasmus; Nielsen, Camilla G; Møller, Charlotte; van der Horst, Demi; Peri, Suraj; Balachandran, Siddharth; Huang, Jinrong; Jakobsen, Martin; Svenningsen, Esben B; Poulsen, Thomas B; Bartsch, Lydia; Thielke, Anne L; Luo, Yonglun; Alain, Tommy; Rehwinkel, Jan; Alcamí, Antonio; Hiscott, John; Mogensen, Trine H.; Paludan, Søren R; Holm, Christian K.

    In: Nature Communications, Vol. 11, No. 1, 4938, 10.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Systemic juvenile idiopathic arthritis and recurrent macrophage activation syndrome due to a CASP1 variant causing inflammasome hyperactivation. / Jørgensen, Sofie E; Christiansen, Mette; Høst, Christian; Glerup, Mia; Mahler, Birgitte; Lausten, Mira M; Gad, Hans Henrik; Hartmann, Rune; Herlin, Troels; Mogensen, Trine H.

    In: Rheumatology (Oxford, England), Vol. 59, No. 10, 10.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Deciphering the Role of Host Genetics in Susceptibility to Severe COVID-19. / Carter-Timofte, Madalina Elena; Jørgensen, Sofie Eg; Freytag, Mette Ratzer; Thomsen, Michelle Mølgaard; Brinck Andersen, Nanna Sophie; Al-Mousawi, Ali; Hait, Alon Schneider; Mogensen, Trine H.

    In: Frontiers in Immunology, Vol. 11, 1606, 06.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  9. Published

    Autoinflammatory disease with corneal and mucosal dyskeratosis caused by a novel NLRP1 variant. / Herlin, Troels; Jørgensen, Sofie E; Høst, Christian; Mitchell, Patrick S; Christensen, Maria Hønholt; Laustsen, Mira; Larsen, Dorthe A; Schmidt, Florian I; Christiansen, Mette; Mogensen, Trine H.

    In: Rheumatology, Vol. 59, No. 9, 2020, p. 2334-2339.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. E-pub ahead of print
  11. 2019
  12. Published

    Defective interferon priming and impaired antiviral responses in a patient with an IRF7 variant and severe influenza. / Thomsen, Michelle M; Jørgensen, Sofie E; Gad, Hans Henrik; Storgaard, Merete; Gjedsted, Jakob; Christiansen, Mette; Hartmann, Rune; Mogensen, Trine H.

    In: Medical Microbiology and Immunology, Vol. 208, No. 6, 12.2019, p. 869-876.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Identification of an IRF3 variant and defective antiviral interferon responses in a patient with severe influenza. / Thomsen, Michelle M; Jørgensen, Sofie E; Storgaard, Merete; Kristensen, Lasse S; Gjedsted, Jakob; Christiansen, Mette; Gad, Hans Henrik; Hartmann, Rune; Mogensen, Trine H.

    In: European Journal of Immunology, Vol. 49, No. 11, 11.2019, p. 2111-2114.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperComment/debate/letter to the editorResearchpeer-review

  14. Published

    Impaired immune responses to herpesviruses and microbial ligands in patients with MonoMAC. / Mardahl, Maibritt; Jørgensen, Sofie Eg; Schneider, Alon; Raaschou-Jensen, Klas; Holm, Mette; Veirum, Jens; Kristensen, Thomas K; Johansen, Isik S; Christiansen, Mette; Assing, Kristian; Mogensen, Trine H.

    In: British Journal of Haematology, Vol. 186, No. 3, 08.2019, p. 471-476.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Host genetics, innate immune responses, and cellular death pathways in poliomyelitis patients. / Andersen, Nanna Sophie B.; Larsen, Simon M.; Nissen, Sara K.; Jørgensen, Sofie E.; Mardahl, Maibritt; Christiansen, Mette; Kay, Lise; Mogensen, Trine H.

    In: Frontiers in Microbiology, Vol. 10, 1495, 07.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined. / Kaleviste, Epp; Saare, Mario; Leahy, Timothy Ronan; Bondet, Vincent; Duffy, Darragh; Mogensen, Trine H.; Jørgensen, Sofie E.; Nurm, Helke; Ip, Winnie; Davies, E. Graham; Sauer, Sascha; Syvänen, Ann Christine; Milani, Lili; Peterson, Pärt; Kisand, Kai.

    In: European Journal of Immunology, Vol. 49, No. 5, 2019, p. 790-800.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. 2018
  18. Published

    Whole Exome Sequencing of HIV-1 long-term non-progressors identifies rare variants in genes encoding innate immune sensors and signaling molecules. / Nissen, Sara Konstantin; Christiansen, Mette; Helleberg, Marie; Kjær, Kathrine; Jørgensen, Sofie Eg; Gerstoft, Jan; Katzenstein, Terese L; Benfield, Thomas; Kronborg, Gitte; Larsen, Carsten S; Laursen, Alex; Pedersen, Gitte; Jakobsen, Martin R; Tolstrup, Martin; Mogensen, Trine H.

    In: Scientific Reports, Vol. 8, No. 1, 15.10.2018, p. 15253.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Defective RNA sensing by RIG-I in severe influenza virus infection. / Jørgensen, Sofie Eg; Christiansen, Mette; Ryø, Laura Barrett; Gad, Hans Henrik; Gjedsted, Jakob; Staeheli, Peter; Mikkelsen, Jacob Giehm; Storgaard, Merete; Hartmann, Rune; Mogensen, Trine Hyrup.

    In: Clinical and Experimental Immunology, Vol. 192, No. 3, 06.2018, p. 366-376.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. 2016
  21. Published

    Ectodermal dysplasia with immunodeficiency caused by a branch-point mutation in IKBKG/NEMO. / Jørgensen, Sofie E.; Bøttger, Pernille; Kofod-Olsen, Emil; Holm, Mette; Mørk, Nanna; Ørntoft, Torben Falck; Sørensen, Uffe; Bernth-Jensen, Jens Magnus; Herlin, Troels; Veirum, Jens; Larsen, Carsten S.; Østergaard, Lars Jørgen; Hartmann, Rune; Christiansen, Mette; Mogensen, Trine.

    In: Journal of Allergy and Clinical Immunology, Vol. 138, No. 6, 2016, p. 1706-1709.e4.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. 2015
  23. Published

    Altered fraction of regulatory B and T cells is correlated with autoimmune phenomena and splenomegaly in patients with CVID. / Kofod-Olsen, Emil; Jørgensen, Sofie Eg; Nissen, Sara Konstantin; Westh, Lena; Møller, Bjarne K; Østergaard, Lars; Larsen, Carsten S; Mogensen, Trine H.

    In: Clinical Immunology, Vol. 162, 14.11.2015, p. 49-57.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Functional IRF3 deficiency in a patient with herpes simplex encephalitis. / Andersen, Line Lykke; Mørk, Nanna; Reinert, Line S; Kofod-Olsen, Emil; Narita, Ryo; Jørgensen, Sofie E; Skipper, Kristian A; Höning, Klara; Gad, Hans Henrik; Østergaard, Lars; Ørntoft, Torben F; Hornung, Veit; Paludan, Søren R; Mikkelsen, Jacob Giehm; Fujita, Takashi; Christiansen, Mette; Hartmann, Rune; Mogensen, Trine H.

    In: Journal of Experimental Medicine, Vol. 212, No. 9, 2015, p. 1371-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. 2014
  26. Published

    Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway. / Hansen, Kathrine; Prabakaran, Thaneas; Laustsen, Anders; Jørgensen, Sofie E; Rahbek, Stine Hess; Jensen, Søren B; Nielsen, Rikke; Leber, Jess H; Decker, Thomas; Horan, Kristy A; Jakobsen, Martin R; Paludan, Søren R.

    In: E M B O Journal, Vol. 33, No. 15, 01.08.2014, p. 1654-66.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Inflammatory Cytokines Break Down Intrinsic Immunological Tolerance of Human Primary Keratinocytes to Cytosolic DNA. / Chiliveru, Srikanth; Rahbek, Stine H; Jensen, Simon K; Jørgensen, Sofie E; Nissen, Sara K; Christiansen, Stig H; Mogensen, Trine H; Jakobsen, Martin R; Iversen, Lars; Johansen, Claus; Paludan, Søren R.

    In: Journal of Immunology, 2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review