Søren Riis Paludan

  1. 2019
  2. Published

    Intracellular bacteria engage a STING–TBK1–MVB12b pathway to enable paracrine cGAS–STING signalling. / Nandakumar, Ramya; Tschismarov, Roland; Meissner, Felix; Prabakaran, Thaneas; Krissanaprasit, Abhichart; Farahani, Ensieh; Zhang, Bao cun; Assil, Sonia; Martin, Amandine; Bertrams, Wilhelm; Holm, Christian K.; Ablasser, Andrea; Klause, Tanja; Thomsen, Martin K.; Schmeck, Bernd; Howard, Kenneth A.; Henry, Thomas; Gothelf, Kurt V.; Decker, Thomas; Paludan, Søren R.

    In: Nature Microbiology, Vol. 4, 04.2019, p. 701-713.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    DNA-stimulated cell death : implications for host defence, inflammatory diseases and cancer. / Paludan, Søren R.; Reinert, Line S.; Hornung, Veit.

    In: Nature Reviews Immunology, Vol. 19, No. 3, 01.03.2019, p. 141-153.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  4. Published

    The herpesviral antagonist m152 reveals differential activation of STING-dependent IRF and NF-κB signaling and STING's dual role during MCMV infection. / Stempel, Markus; Chan, Baca; Juranić Lisnić, Vanda; Krmpotić, Astrid; Hartung, Josephine; Paludan, Søren R.; Füllbrunn, Nadia; Lemmermann, Niels A.W.; Brinkmann, Melanie M.

    In: EMBO Journal, Vol. 38, No. 5, e100983, 01.03.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Mutations in RNA Polymerase III genes and defective DNA sensing in adults with varicella-zoster virus CNS infection. / Carter-Timofte, Madalina E; Hansen, Anders F; Christiansen, Mette; Paludan, Søren R; Mogensen, Trine H.

    In: Genes and Immunity, Vol. 20, No. 3, 03.2019, p. 214-223.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Non-covalent hitchhiking on endogenous carriers as a protraction mechanism for antiviral macromolecular prodrugs. / Frich, Camilla Kaas; Krüger, Franziska; Walther, Raoul; Domar, Cecilie; Andersen, Anna H. F.; Tvilum, Anne ; Dagnæs-Hansen, Frederik; Denton, Paul W.; Tolstrup, Martin; Paludan, Søren Riis; Münch, jJan; Zelikin, Alexander N.

    In: Journal of Controlled Release, Vol. 294, 28.01.2019, p. 298-310.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Cellular Requirements for Sensing and Elimination of Incoming HSV-1 DNA and Capsids. / Sun, Chenglong; Luecke, Stefanie; Bodda, Chiranjeevi; Jønsson, Kasper L.; Cai, Yujia; Zhang, Bao Cun; Jensen, Søren B.; Nordentoft, Iver; Jensen, Jacob M.; Jakobsen, Martin R.; Paludan, Sren R.

    In: Journal of Interferon and Cytokine Research, Vol. 39, No. 4, 2019, p. 191-204.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. E-pub ahead of print

    The cGAS-STING pathway is a therapeutic target in a preclinical model of hepatocellular carcinoma. / Thomsen, Martin K.; Skouboe, Morten K.; Boularan, Cedric; Vernejoul, Fabienne; Lioux, Thierry; Leknes, Siv L.; Berthelsen, Martin F.; Riedel, Maria; Cai, Huiqiang; Joseph, Justin V.; Perouzel, Eric; Tiraby, Michele; Vendelbo, Mikkel H.; Paludan, Søren R.

    In: Oncogene, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. 2018
  10. Published

    Varicella-zoster virus CNS vasculitis and RNA polymerase III gene mutation in identical twins. / Carter-Timofte, Madalina E; Hansen, Anders F; Mardahl, Maibritt; Fribourg, Sébastien; Rapaport, Franck; Zhang, Shen-Ying; Casanova, Jean-Laurent; Paludan, Søren R; Christiansen, Mette; Larsen, Carsten S; Mogensen, Trine H.

    In: Neurology(R) neuroimmunology & neuroinflammation, Vol. 5, No. 6, 11.2018, p. e500.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    RNA Polymerase III as a Gatekeeper to Prevent Severe VZV Infections. / Carter-Timofte, Madalina E; Paludan, Søren R; Mogensen, Trine H.

    In: Trends in Molecular Medicine, Vol. 24, No. 10, 10.2018, p. 904-915.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  12. Published

    Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death. / Reimer, Lasse; Lund, Louise Buur; Betzer, Cristine; Zheng, Jin; Nielsen, Lærke Dalsgaard; Kofoed, Rikke Hahn; Lassen, Louise Berkhoudt; Bølcho, Ulrik; Paludan, Søren Riis; Fog, Karina; Jensen, Poul Henning.

    In: Neurobiology of Disease, 01.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1. / Prabakaran, Thaneas; Bodda, Chiranjeevi; Krapp, Christian; Zhang, Bao-Cun; Christensen, Maria H; Sun, Chenglong; Reinert, Line; Cai, Yujia; Jensen, Søren B; Skouboe, Morten K; Nyengaard, Jens R; Thompson, Craig B; Lebbink, Robert Jan; Sen, Ganes C; van Loo, Geert; Nielsen, Rikke; Komatsu, Masaaki; Nejsum, Lene N; Jakobsen, Martin R; Gyrd-Hansen, Mads; Paludan, Søren R.

    In: E M B O Journal, Vol. 37, No. 8, E97858, 13.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice. / Skouboe, Morten K; Knudsen, Alice; Reinert, Line S; Boularan, Cedric; Lioux, Thierry; Perouzel, Eric; Thomsen, Martin K; Paludan, Søren R.

    In: P L o S Pathogens, Vol. 14, No. 4, e1006976, 02.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. 2017
  16. Published

    Human B cells fail to secrete type I interferons upon cytoplasmic DNA exposure. / Gram, Anna M.; Sun, Chenglong; Landman, Sanne L.; Oosenbrug, Timo; Koppejan, Hester J.; Kwakkenbos, Mark J.; Hoeben, Rob C.; Paludan, Soren R.; Ressing, Maaike E.

    In: Molecular Immunology, Vol. 91, 11.2017, p. 225-237.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Cutting Edge : Genetic Association between IFI16 Single Nucleotide Polymorphisms and Resistance to Genital Herpes Correlates with IFI16 Expression Levels and HSV-2-Induced IFN-β Expression. / Eriksson, Kristina; Svensson, Alexandra; Hait, Alon S; Schlüter, Kerstin; Tunbäck, Petra; Nordström, Inger; Padyukov, Leonid; Liljeqvist, Jan-Åke; Mogensen, Trine H; Paludan, Søren R.

    In: Journal of Immunology, Vol. 199, No. 8, 15.10.2017, p. 2613-2617.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Molecular requirements for sensing of intracellular microbial nucleic acids by the innate immune system. / Luecke, Stefanie; Paludan, Soren R.

    In: Cytokine, Vol. 98, 10.2017, p. 4-14.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  19. Published

    cGAS is activated by DNA in a length-dependent manner. / Luecke, Stefanie; Holleufer, Andreas; Christensen, Maria H; Jønsson, Kasper L; Boni, Gerardo A; Sørensen, Lambert K; Johannsen, Mogens; Jakobsen, Martin R; Hartmann, Rune; Paludan, Søren R.

    In: E M B O Reports, Vol. 18, No. 10, 10.2017, p. 1707–1715.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections. / Ogunjimi, Benson; Zhang, Shen-Ying; Sørensen, Katrine Biehl; Skipper, Kristian A; Carter-Timofte, Madalina; Kerner, Gaspard; Luecke, Stefanie; Prabakaran, Thaneas; Cai, Yujia; Meester, Josephina; Bartholomeus, Esther; Bolar, Nikhita Ajit; Vandeweyer, Geert; Claes, Charlotte; Sillis, Yasmine; Lorenzo, Lazaro; Fiorenza, Raffaele A; Boucherit, Soraya; Dielman, Charlotte; Heynderickx, Steven; Elias, George; Kurotova, Andrea; Auwera, Ann Vander; Verstraete, Lieve; Lagae, Lieven; Verhelst, Helene; Jansen, Anna; Ramet, Jose; Suls, Arvid; Smits, Evelien; Ceulemans, Berten; Van Laer, Lut; Plat Wilson, Genevieve; Kreth, Jonas; Picard, Capucine; Von Bernuth, Horst; Fluss, Joël; Chabrier, Stephane; Abel, Laurent; Mortier, Geert; Fribourg, Sebastien; Mikkelsen, Jacob Giehm; Casanova, Jean-Laurent; Paludan, Søren R; Mogensen, Trine H.

    In: Journal of Clinical Investigation, 01.09.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP. / Jønsson, K L; Laustsen, A; Krapp, C; Skipper, K A; Thavachelvam, K; Hotter, D; Egedal, J H; Kjolby, M; Mohammadi, P; Prabakaran, T; Sørensen, L K; Sun, C; Jensen, S B; Holm, C K; Lebbink, Robert Jan; Johannsen, M; Nyegaard, M; Mikkelsen, J G; Kirchhoff, F; Paludan, S R; Jakobsen, M R.

    In: Nature Communications, Vol. 8, 14391, 10.02.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Viral evasion of DNA-stimulated innate immune responses. / Christensen, Maria H.; Paludan, Soren R.

    In: Cellular & molecular immunology, Vol. 14, No. 1, 01.2017, p. 4-13.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  23. 2016
  24. Published

    Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS. / Reinert, Line S; Lopušná, Katarína; Winther, Henriette; Sun, Chenglong; Thomsen, Martin K; Nandakumar, Ramya; Mogensen, Trine H; Meyer, Morten; Vægter, Christian; Nyengaard, Jens R; Fitzgerald, Katherine A; Paludan, Søren R.

    In: Nature Communications, Vol. 7, 13348, 10.11.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Gene-environmental interactions between genetic variants in antiviral response genes and prenatal maternal infections in schizophrenia. / Manikandan, Veera; Reinert, Line; Paludan, Søren Riis; Grove, Jakob; Nielsen, Philip Finn Rising; Hougaard, David M.; Nordentoft, Merete; Werge, Thomas; Børglum, Anders; Mortensen, Preben Bo; Demontis, Ditte.

    2016. Poster session presented at American Society of Human Genetics 2016, Vancouver, Canada.

    Research output: Contribution to conferencePosterResearch

  26. Published

    HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression. / Christensen, Maria H.; Jensen, Søren B.; Miettinen, Juho J.; Luecke, Stefanie; Prabakaran, Thaneas; Reinert, Line S.; Mettenleiter, Thomas; Chen, Zhijian J.; Knipe, David M.; Sandri-Goldin, Rozanne M.; Enquist, Lynn W.; Hartmann, Rune; Mogensen, Trine H.; Rice, Stephen A.; Nyman, Tuula A.; Matikainen, Sampsa; Paludan, Søren R.

    In: The EMBO Journal, Vol. 35, No. 13, 01.07.2016, p. 1385-1399.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection. / Thomsen, Martin K; Nandakumar, Ramya; Stadler, Daniela; Malo, Antje; Valls, Roser Marin; Wang, Fan; Reinert, Line S; Dagnaes-Hansen, Frederik; Hollensen, Anne Kruse; Mikkelsen, Jacob Giehm; Protzer, Ulrike; Paludan, Søren R.

    In: Hepatology, Vol. 64, No. 3, 16.06.2016, p. 746-759.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses. / Holm, Christian K; Rahbek, Stine H; Gad, Hans Henrik; Bak, Rasmus O; Jakobsen, Martin R; Jiang, Zhaozaho; Hansen, Anne Louise; Jensen, Simon K; Sun, Chenglong; Thomsen, Martin K; Laustsen, Anders; Nielsen, Camilla G; Severinsen, Kasper; Xiong, Yingluo; Burdette, Dara L; Hornung, Veit; Lebbink, Robert Jan; Duch, Mogens; Fitzgerald, Katherine A; Bahrami, Shervin; Mikkelsen, Jacob Giehm; Hartmann, Rune; Paludan, Søren R.

    In: Nature Communications, Vol. 7, 10680, 19.02.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). / Klionsky, Daniel J; Abdelmohsen, Kotb; Abe, Akihisa; Abedin, Md Joynal; Abeliovich, Hagai; Acevedo Arozena, Abraham; Adachi, Hiroaki; Adams, Christopher M; Adams, Peter D; Adeli, Khosrow; Adhihetty, Peter J; Adler, Sharon G; Agam, Galila; Agarwal, Rajesh; Aghi, Manish K; Agnello, Maria; Agostinis, Patrizia; Aguilar, Patricia V; Aguirre-Ghiso, Julio; Airoldi, Edoardo M; Ait-Si-Ali, Slimane; Akematsu, Takahiko; Akporiaye, Emmanuel T; Al-Rubeai, Mohamed; Albaiceta, Guillermo M; Albanese, Chris; Albani, Diego; Albert, Matthew L; Aldudo, Jesus; Algül, Hana; Alirezaei, Mehrdad; Alloza, Iraide; Almasan, Alexandru; Almonte-Beceril, Maylin; Alnemri, Emad S; Alonso, Covadonga; Altan-Bonnet, Nihal; Altieri, Dario C; Alvarez, Silvia; Alvarez-Erviti, Lydia; Alves, Sandro; Amadoro, Giuseppina; Amano, Atsuo; Amantini, Consuelo; Ambrosio, Santiago; Amelio, Ivano; Amer, Amal O; Amessou, Mohamed; Amon, Angelika; An, Zhenyi; Anania, Frank A; Andersen, Stig U; Andley, Usha P; Andreadi, Catherine K; Andrieu-Abadie, Nathalie; Anel, Alberto; Ann, David K; Anoopkumar-Dukie, Shailendra; Antonioli, Manuela; Aoki, Hiroshi; Apostolova, Nadezda; Aquila, Saveria; Aquilano, Katia; Araki, Koichi; Arama, Eli; Aranda, Agustin; Araya, Jun; Arcaro, Alexandre; Arias, Esperanza; Arimoto, Hirokazu; Ariosa, Aileen R; Armstrong, Jane L; Arnould, Thierry; Arsov, Ivica; Asanuma, Katsuhiko; Askanas, Valerie; Asselin, Eric; Atarashi, Ryuichiro; Atherton, Sally S; Atkin, Julie D; Attardi, Laura D; Auberger, Patrick; Auburger, Georg; Aurelian, Laure; Autelli, Riccardo; Avagliano, Laura; Avantaggiati, Maria Laura; Avrahami, Limor; Awale, Suresh; Azad, Neelam; Bachetti, Tiziana; Backer, Jonathan M; Bae, Dong-Hun; Bae, Jae-Sung; Bae, Ok-Nam; Bae, Soo Han; Baehrecke, Eric H; Baek, Seung-Hoon; Baghdiguian, Stephen; Bagniewska-Zadworna, Agnieszka; Bai, Hua; Bai, Jie; Bai, Xue-Yuan; Bailly, Yannick; Balaji, Kithiganahalli Narayanaswamy; Balduini, Walter; Ballabio, Andrea; Balzan, Rena; Banerjee, Rajkumar; Bánhegyi, Gábor; Bao, Haijun; Barbeau, Benoit; Barrachina, Maria D; Barreiro, Esther; Bartel, Bonnie; Bartolomé, Alberto; Bassham, Diane C; Bassi, Maria Teresa; Bast, Robert C; Basu, Alakananda; Batista, Maria Teresa; Batoko, Henri; Battino, Maurizio; Bauckman, Kyle; Baumgarner, Bradley L; Bayer, K Ulrich; Beale, Rupert; Beaulieu, Jean-François; Beck, George R; Becker, Christoph; Beckham, J David; Bédard, Pierre-André; Bednarski, Patrick J; Begley, Thomas J; Behl, Christian; Behrends, Christian; Behrens, Georg Mn; Behrns, Kevin E; Bejarano, Eloy; Belaid, Amine; Belleudi, Francesca; Bénard, Giovanni; Berchem, Guy; Bergamaschi, Daniele; Bergami, Matteo; Berkhout, Ben; Berliocchi, Laura; Bernard, Amélie; Bernard, Monique; Bernassola, Francesca; Bertolotti, Anne; Bess, Amanda S; Besteiro, Sébastien; Bettuzzi, Saverio; Bhalla, Savita; Bhattacharyya, Shalmoli; Bhutia, Sujit K; Biagosch, Caroline; Bianchi, Michele Wolfe; Biard-Piechaczyk, Martine; Billes, Viktor; Bincoletto, Claudia; Bingol, Baris; Bird, Sara W; Bitoun, Marc; Bjedov, Ivana; Blackstone, Craig; Blanc, Lionel; Blanco, Guillermo A; Blomhoff, Heidi Kiil; Boada-Romero, Emilio; Böckler, Stefan; Boes, Marianne; Boesze-Battaglia, Kathleen; Boise, Lawrence H; Bolino, Alessandra; Boman, Andrea; Bonaldo, Paolo; Bordi, Matteo; Bosch, Jürgen; Botana, Luis M; Botti, Joelle; Bou, German; Bouché, Marina; Bouchecareilh, Marion; Boucher, Marie-Josée; Boulton, Michael E; Bouret, Sebastien G; Boya, Patricia; Boyer-Guittaut, Michaël; Bozhkov, Peter V; Brady, Nathan; Braga, Vania Mm; Brancolini, Claudio; Braus, Gerhard H; Bravo-San Pedro, José M; Brennan, Lisa A; Bresnick, Emery H; Brest, Patrick; Bridges, Dave; Bringer, Marie-Agnès; Brini, Marisa; Brito, Glauber C; Brodin, Bertha; Brookes, Paul S; Brown, Eric J; Brown, Karen; Broxmeyer, Hal E; Bruhat, Alain; Brum, Patricia Chakur; Brumell, John H; Brunetti-Pierri, Nicola; Bryson-Richardson, Robert J; Buch, Shilpa; Buchan, Alastair M; Budak, Hikmet; Bulavin, Dmitry V; Bultman, Scott J; Bultynck, Geert; Bumbasirevic, Vladimir; Burelle, Yan; Burke, Robert E; Burmeister, Margit; Bütikofer, Peter; Caberlotto, Laura; Cadwell, Ken; Cahova, Monika; Cai, Dongsheng; Cai, Jingjing; Cai, Qian; Calatayud, Sara; Camougrand, Nadine; Campanella, Michelangelo; Campbell, Grant R; Campbell, Matthew; Campello, Silvia; Candau, Robin; Caniggia, Isabella; Cantoni, Lavinia; Cao, Lizhi; Caplan, Allan B; Caraglia, Michele; Cardinali, Claudio; Cardoso, Sandra Morais; Carew, Jennifer S; Carleton, Laura A; Carlin, Cathleen R; Carloni, Silvia; Carlsson, Sven R; Carmona-Gutierrez, Didac; Carneiro, Leticia Am; Carnevali, Oliana; Carra, Serena; Carrier, Alice; Carroll, Bernadette; Casas, Caty; Casas, Josefina; Cassinelli, Giuliana; Castets, Perrine; Castro-Obregon, Susana; Cavallini, Gabriella; Ceccherini, Isabella; Cecconi, Francesco; Cederbaum, Arthur I; Ceña, Valentín; Cenci, Simone; Cerella, Claudia; Cervia, Davide; Cetrullo, Silvia; Chaachouay, Hassan; Chae, Han-Jung; Chagin, Andrei S; Chai, Chee-Yin; Chakrabarti, Gopal; Chamilos, Georgios; Chan, Edmond Yw; Chan, Matthew Tv; Chandra, Dhyan; Chandra, Pallavi; Chang, Chih-Peng; Chang, Raymond Chuen-Chung; Chang, Ta Yuan; Chatham, John C; Chatterjee, Saurabh; Chauhan, Santosh; Che, Yongsheng; Cheetham, Michael E; Cheluvappa, Rajkumar; Chen, Chun-Jung; Chen, Gang; Chen, Guang-Chao; Chen, Guoqiang; Chen, Hongzhuan; Chen, Jeff W; Chen, Jian-Kang; Chen, Min; Chen, Mingzhou; Chen, Peiwen; Chen, Qi; Chen, Quan; Chen, Shang-Der; Chen, Si; Chen, Steve S-L; Chen, Wei; Chen, Wei-Jung; Chen, Wen Qiang; Chen, Wenli; Chen, Xiangmei; Chen, Yau-Hung; Chen, Ye-Guang; Chen, Yin; Chen, Yingyu; Chen, Yongshun; Chen, Yu-Jen; Chen, Yue-Qin; Chen, Yujie; Chen, Zhen; Chen, Zhong; Cheng, Alan; Cheng, Christopher Hk; Cheng, Hua; Cheong, Heesun; Cherry, Sara; Chesney, Jason; Cheung, Chun Hei Antonio; Chevet, Eric; Chi, Hsiang Cheng; Chi, Sung-Gil; Chiacchiera, Fulvio; Chiang, Hui-Ling; Chiarelli, Roberto; Chiariello, Mario; Chieppa, Marcello; Chin, Lih-Shen; Chiong, Mario; Chiu, Gigi Nc; Cho, Dong-Hyung; Cho, Ssang-Goo; Cho, William C; Cho, Yong-Yeon; Cho, Young-Seok; Choi, Augustine Mk; Choi, Eui-Ju; Choi, Eun-Kyoung; Choi, Jayoung; Choi, Mary E; Choi, Seung-Il; Chou, Tsui-Fen; Chouaib, Salem; Choubey, Divaker; Choubey, Vinay; Chow, Kuan-Chih; Chowdhury, Kamal; Chu, Charleen T; Chuang, Tsung-Hsien; Chun, Taehoon; Chung, Hyewon; Chung, Taijoon; Chung, Yuen-Li; Chwae, Yong-Joon; Cianfanelli, Valentina; Ciarcia, Roberto; Ciechomska, Iwona A; Ciriolo, Maria Rosa; Cirone, Mara; Claerhout, Sofie; Clague, Michael J; Clària, Joan; Clarke, Peter Gh; Clarke, Robert; Clementi, Emilio; Cleyrat, Cédric; Cnop, Miriam; Coccia, Eliana M; Cocco, Tiziana; Codogno, Patrice; Coers, Jörn; Cohen, Ezra Ew; Colecchia, David; Coletto, Luisa; Coll, Núria S; Colucci-Guyon, Emma; Comincini, Sergio; Condello, Maria; Cook, Katherine L; Coombs, Graham H; Cooper, Cynthia D; Cooper, J Mark; Coppens, Isabelle; Corasaniti, Maria Tiziana; Corazzari, Marco; Corbalan, Ramon; Corcelle-Termeau, Elisabeth; Cordero, Mario D; Corral-Ramos, Cristina; Corti, Olga; Cossarizza, Andrea; Costelli, Paola; Costes, Safia; Cotman, Susan L; Coto-Montes, Ana; Cottet, Sandra; Couve, Eduardo; Covey, Lori R; Cowart, L Ashley; Cox, Jeffery S; Coxon, Fraser P; Coyne, Carolyn B; Cragg, Mark S; Craven, Rolf J; Crepaldi, Tiziana; Crespo, Jose L; Criollo, Alfredo; Crippa, Valeria; Cruz, Maria Teresa; Cuervo, Ana Maria; Cuezva, Jose M; Cui, Taixing; Cutillas, Pedro R; Czaja, Mark J; Czyzyk-Krzeska, Maria F; Dagda, Ruben K; Dahmen, Uta; Dai, Chunsun; Dai, Wenjie; Dai, Yun; Dalby, Kevin N; Dalla Valle, Luisa; Dalmasso, Guillaume; D'Amelio, Marcello; Damme, Markus; Darfeuille-Michaud, Arlette; Dargemont, Catherine; Darley-Usmar, Victor M; Dasarathy, Srinivasan; Dasgupta, Biplab; Dash, Srikanta; Dass, Crispin R; Davey, Hazel Marie; Davids, Lester M; Dávila, David; Davis, Roger J; Dawson, Ted M; Dawson, Valina L; Daza, Paula; de Belleroche, Jackie; de Figueiredo, Paul; de Figueiredo, Regina Celia Bressan Queiroz; de la Fuente, José; De Martino, Luisa; De Matteis, Antonella; De Meyer, Guido Ry; De Milito, Angelo; De Santi, Mauro; de Souza, Wanderley; De Tata, Vincenzo; De Zio, Daniela; Debnath, Jayanta; Dechant, Reinhard; Decuypere, Jean-Paul; Deegan, Shane; Dehay, Benjamin; Del Bello, Barbara; Del Re, Dominic P; Delage-Mourroux, Régis; Delbridge, Lea Md; Deldicque, Louise; Delorme-Axford, Elizabeth; Deng, Yizhen; Dengjel, Joern; Denizot, Melanie; Dent, Paul; Der, Channing J; Deretic, Vojo; Derrien, Benoît; Deutsch, Eric; Devarenne, Timothy P; Devenish, Rodney J; Di Bartolomeo, Sabrina; Di Daniele, Nicola; Di Domenico, Fabio; Di Nardo, Alessia; Di Paola, Simone; Di Pietro, Antonio; Di Renzo, Livia; DiAntonio, Aaron; Díaz-Araya, Guillermo; Díaz-Laviada, Ines; Diaz-Meco, Maria T; Diaz-Nido, Javier; Dickey, Chad A; Dickson, Robert C; Diederich, Marc; Digard, Paul; Dikic, Ivan; Dinesh-Kumar, Savithrama P; Ding, Chan; Ding, Wen-Xing; Ding, Zufeng; Dini, Luciana; Distler, Jörg Hw; Diwan, Abhinav; Djavaheri-Mergny, Mojgan; Dmytruk, Kostyantyn; Dobson, Renwick Cj; Doetsch, Volker; Dokladny, Karol; Dokudovskaya, Svetlana; Donadelli, Massimo; Dong, X Charlie; Dong, Xiaonan; Dong, Zheng; Donohue, Terrence M; Doran, Kelly S; D'Orazi, Gabriella; Dorn, Gerald W; Dosenko, Victor; Dridi, Sami; Drucker, Liat; Du, Jie; Du, Li-Lin; Du, Lihuan; du Toit, André; Dua, Priyamvada; Duan, Lei; Duann, Pu; Dubey, Vikash Kumar; Duchen, Michael R; Duchosal, Michel A; Duez, Helene; Dugail, Isabelle; Dumit, Verónica I; Duncan, Mara C; Dunlop, Elaine A; Dunn, William A; Dupont, Nicolas; Dupuis, Luc; Durán, Raúl V; Durcan, Thomas M; Duvezin-Caubet, Stéphane; Duvvuri, Umamaheswar; Eapen, Vinay; Ebrahimi-Fakhari, Darius; Echard, Arnaud; Eckhart, Leopold; Edelstein, Charles L; Edinger, Aimee L; Eichinger, Ludwig; Eisenberg, Tobias; Eisenberg-Lerner, Avital; Eissa, N Tony; El-Deiry, Wafik S; El-Khoury, Victoria; Elazar, Zvulun; Eldar-Finkelman, Hagit; Elliott, Chris Jh; Emanuele, Enzo; Emmenegger, Urban; Engedal, Nikolai; Engelbrecht, Anna-Mart; Engelender, Simone; Enserink, Jorrit M; Erdmann, Ralf; Erenpreisa, Jekaterina; Eri, Rajaraman; Eriksen, Jason L; Erman, Andreja; Escalante, Ricardo; Eskelinen, Eeva-Liisa; Espert, Lucile; Esteban-Martínez, Lorena; Evans, Thomas J; Fabri, Mario; Fabrias, Gemma; Fabrizi, Cinzia; Facchiano, Antonio; Færgeman, Nils J; Faggioni, Alberto; Fairlie, W Douglas; Fan, Chunhai; Fan, Daping; Fan, Jie; Fang, Shengyun; Fanto, Manolis; Fanzani, Alessandro; Farkas, Thomas; Faure, Mathias; Favier, Francois B; Fearnhead, Howard; Federici, Massimo; Fei, Erkang; Felizardo, Tania C; Feng, Hua; Feng, Yibin; Feng, Yuchen; Ferguson, Thomas A; Fernández, Álvaro F; Fernandez-Barrena, Maite G; Fernandez-Checa, Jose C; Fernández-López, Arsenio; Fernandez-Zapico, Martin E; Feron, Olivier; Ferraro, Elisabetta; Ferreira-Halder, Carmen Veríssima; Fesus, Laszlo; Feuer, Ralph; Fiesel, Fabienne C; Filippi-Chiela, Eduardo C; Filomeni, Giuseppe; Fimia, Gian Maria; Fingert, John H; Finkbeiner, Steven; Finkel, Toren; Fiorito, Filomena; Fisher, Paul B; Flajolet, Marc; Flamigni, Flavio; Florey, Oliver; Florio, Salvatore; Floto, R Andres; Folini, Marco; Follo, Carlo; Fon, Edward A; Fornai, Francesco; Fortunato, Franco; Fraldi, Alessandro; Franco, Rodrigo; Francois, Arnaud; François, Aurélie; Frankel, Lisa B; Fraser, Iain Dc; Frey, Norbert; Freyssenet, Damien G; Frezza, Christian; Friedman, Scott L; Frigo, Daniel E; Fu, Dongxu; Fuentes, José M; Fueyo, Juan; Fujitani, Yoshio; Fujiwara, Yuuki; Fujiya, Mikihiro; Fukuda, Mitsunori; Fulda, Simone; Fusco, Carmela; Gabryel, Bozena; Gaestel, Matthias; Gailly, Philippe; Gajewska, Malgorzata; Galadari, Sehamuddin; Galili, Gad; Galindo, Inmaculada; Galindo, Maria F; Galliciotti, Giovanna; Galluzzi, Lorenzo; Galluzzi, Luca; Galy, Vincent; Gammoh, Noor; Gandy, Sam; Ganesan, Anand K; Ganesan, Swamynathan; Ganley, Ian G; Gannagé, Monique; Gao, Fen-Biao; Gao, Feng; Gao, Jian-Xin; García Nannig, Lorena; García Véscovi, Eleonora; Garcia-Macía, Marina; Garcia-Ruiz, Carmen; Garg, Abhishek D; Garg, Pramod Kumar; Gargini, Ricardo; Gassen, Nils Christian; Gatica, Damián; Gatti, Evelina; Gavard, Julie; Gavathiotis, Evripidis; Ge, Liang; Ge, Pengfei; Ge, Shengfang; Gean, Po-Wu; Gelmetti, Vania; Genazzani, Armando A; Geng, Jiefei; Genschik, Pascal; Gerner, Lisa; Gestwicki, Jason E; Gewirtz, David A; Ghavami, Saeid; Ghigo, Eric; Ghosh, Debabrata; Giammarioli, Anna Maria; Giampieri, Francesca; Giampietri, Claudia; Giatromanolaki, Alexandra; Gibbings, Derrick J; Gibellini, Lara; Gibson, Spencer B; Ginet, Vanessa; Giordano, Antonio; Giorgini, Flaviano; Giovannetti, Elisa; Girardin, Stephen E; Gispert, Suzana; Giuliano, Sandy; Gladson, Candece L; Glavic, Alvaro; Gleave, Martin; Godefroy, Nelly; Gogal, Robert M; Gokulan, Kuppan; Goldman, Gustavo H; Goletti, Delia; Goligorsky, Michael S; Gomes, Aldrin V; Gomes, Ligia C; Gomez, Hernando; Gomez-Manzano, Candelaria; Gómez-Sánchez, Rubén; Gonçalves, Dawit Ap; Goncu, Ebru; Gong, Qingqiu; Gongora, Céline; Gonzalez, Carlos B; Gonzalez-Alegre, Pedro; Gonzalez-Cabo, Pilar; González-Polo, Rosa Ana; Goping, Ing Swie; Gorbea, Carlos; Gorbunov, Nikolai V; Goring, Daphne R; Gorman, Adrienne M; Gorski, Sharon M; Goruppi, Sandro; Goto-Yamada, Shino; Gotor, Cecilia; Gottlieb, Roberta A; Gozes, Illana; Gozuacik, Devrim; Graba, Yacine; Graef, Martin; Granato, Giovanna E; Grant, Gary Dean; Grant, Steven; Gravina, Giovanni Luca; Green, Douglas R; Greenhough, Alexander; Greenwood, Michael T; Grimaldi, Benedetto; Gros, Frédéric; Grose, Charles; Groulx, Jean-Francois; Gruber, Florian; Grumati, Paolo; Grune, Tilman; Guan, Jun-Lin; Guan, Kun-Liang; Guerra, Barbara; Guillen, Carlos; Gulshan, Kailash; Gunst, Jan; Guo, Chuanyong; Guo, Lei; Guo, Ming; Guo, Wenjie; Guo, Xu-Guang; Gust, Andrea A; Gustafsson, Åsa B; Gutierrez, Elaine; Gutierrez, Maximiliano G; Gwak, Ho-Shin; Haas, Albert; Haber, James E; Hadano, Shinji; Hagedorn, Monica; Hahn, David R; Halayko, Andrew J; Hamacher-Brady, Anne; Hamada, Kozo; Hamai, Ahmed; Hamann, Andrea; Hamasaki, Maho; Hamer, Isabelle; Hamid, Qutayba; Hammond, Ester M; Han, Feng; Han, Weidong; Handa, James T; Hanover, John A; Hansen, Malene; Harada, Masaru; Harhaji-Trajkovic, Ljubica; Harper, J Wade; Harrath, Abdel Halim; Harris, Adrian L; Harris, James; Hasler, Udo; Hasselblatt, Peter; Hasui, Kazuhisa; Hawley, Robert G; Hawley, Teresa S; He, Congcong; He, Cynthia Y; He, Fengtian; He, Gu; He, Rong-Rong; He, Xian-Hui; He, You-Wen; He, Yu-Ying; Heath, Joan K; Hébert, Marie-Josée; Heinzen, Robert A; Helgason, Gudmundur Vignir; Hensel, Michael; Henske, Elizabeth P; Her, Chengtao; Herman, Paul K; Hernández, Agustín; Hernandez, Carlos; Hernández-Tiedra, Sonia; Hetz, Claudio; Hiesinger, P Robin; Higaki, Katsumi; Hilfiker, Sabine; Hill, Bradford G; Hill, Joseph A; Hill, William D; Hino, Keisuke; Hofius, Daniel; Hofman, Paul; Höglinger, Günter U; Höhfeld, Jörg; Holz, Marina K; Hong, Yonggeun; Hood, David A; Hoozemans, Jeroen Jm; Hoppe, Thorsten; Hsu, Chin; Hsu, Chin-Yuan; Hsu, Li-Chung; Hu, Dong; Hu, Guochang; Hu, Hong-Ming; Hu, Hongbo; Hu, Ming Chang; Hu, Yu-Chen; Hu, Zhuo-Wei; Hua, Fang; Hua, Ya; Huang, Canhua; Huang, Huey-Lan; Huang, Kuo-How; Huang, Kuo-Yang; Huang, Shile; Huang, Shiqian; Huang, Wei-Pang; Huang, Yi-Ran; Huang, Yong; Huang, Yunfei; Huber, Tobias B; Huebbe, Patricia; Huh, Won-Ki; Hulmi, Juha J; Hur, Gang Min; Hurley, James H; Husak, Zvenyslava; Hussain, Sabah Na; Hussain, Salik; Hwang, Jung Jin; Hwang, Seungmin; Hwang, Thomas Is; Ichihara, Atsuhiro; Imai, Yuzuru; Imbriano, Carol; Inomata, Megumi; Into, Takeshi; Iovane, Valentina; Iovanna, Juan L; Iozzo, Renato V; Ip, Nancy Y; Irazoqui, Javier E; Iribarren, Pablo; Isaka, Yoshitaka; Isakovic, Aleksandra J; Ischiropoulos, Harry; Isenberg, Jeffrey S; Ishaq, Mohammad; Ishida, Hiroyuki; Ishii, Isao; Ishmael, Jane E; Isidoro, Ciro; Isobe, Ken-Ichi; Isono, Erika; Issazadeh-Navikas, Shohreh; Itahana, Koji; Itakura, Eisuke; Ivanov, Andrei I; Iyer, Anand Krishnan V; Izquierdo, José M; Izumi, Yotaro; Izzo, Valentina; Jäättelä, Marja; Jaber, Nadia; Jackson, Daniel John; Jackson, William T; Jacob, Tony George; Jacques, Thomas S; Jagannath, Chinnaswamy; Jain, Ashish; Jana, Nihar Ranjan; Jang, Byoung Kuk; Jani, Alkesh; Janji, Bassam; Jannig, Paulo Roberto; Jansson, Patric J; Jean, Steve; Jendrach, Marina; Jeon, Ju-Hong; Jessen, Niels; Jeung, Eui-Bae; Jia, Kailiang; Jia, Lijun; Jiang, Hong; Jiang, Hongchi; Jiang, Liwen; Jiang, Teng; Jiang, Xiaoyan; Jiang, Xuejun; Jiang, Xuejun; Jiang, Ying; Jiang, Yongjun; Jiménez, Alberto; Jin, Cheng; Jin, Hongchuan; Jin, Lei; Jin, Meiyan; Jin, Shengkan; Jinwal, Umesh Kumar; Jo, Eun-Kyeong; Johansen, Terje; Johnson, Daniel E; Johnson, Gail Vw; Johnson, James D; Jonasch, Eric; Jones, Chris; Joosten, Leo Ab; Jordan, Joaquin; Joseph, Anna-Maria; Joseph, Bertrand; Joubert, Annie M; Ju, Dianwen; Ju, Jingfang; Juan, Hsueh-Fen; Juenemann, Katrin; Juhász, Gábor; Jung, Hye Seung; Jung, Jae U; Jung, Yong-Keun; Jungbluth, Heinz; Justice, Matthew J; Jutten, Barry; Kaakoush, Nadeem O; Kaarniranta, Kai; Kaasik, Allen; Kabuta, Tomohiro; Kaeffer, Bertrand; Kågedal, Katarina; Kahana, Alon; Kajimura, Shingo; Kakhlon, Or; Kalia, Manjula; Kalvakolanu, Dhan V; Kamada, Yoshiaki; Kambas, Konstantinos; Kaminskyy, Vitaliy O; Kampinga, Harm H; Kandouz, Mustapha; Kang, Chanhee; Kang, Rui; Kang, Tae-Cheon; Kanki, Tomotake; Kanneganti, Thirumala-Devi; Kanno, Haruo; Kanthasamy, Anumantha G; Kantorow, Marc; Kaparakis-Liaskos, Maria; Kapuy, Orsolya; Karantza, Vassiliki; Karim, Md Razaul; Karmakar, Parimal; Kaser, Arthur; Kaushik, Susmita; Kawula, Thomas; Kaynar, A Murat; Ke, Po-Yuan; Ke, Zun-Ji; Kehrl, John H; Keller, Kate E; Kemper, Jongsook Kim; Kenworthy, Anne K; Kepp, Oliver; Kern, Andreas; Kesari, Santosh; Kessel, David; Ketteler, Robin; Kettelhut, Isis do Carmo; Khambu, Bilon; Khan, Muzamil Majid; Khandelwal, Vinoth Km; Khare, Sangeeta; Kiang, Juliann G; Kiger, Amy A; Kihara, Akio; Kim, Arianna L; Kim, Cheol Hyeon; Kim, Deok Ryong; Kim, Do-Hyung; Kim, Eung Kweon; Kim, Hye Young; Kim, Hyung-Ryong; Kim, Jae-Sung; Kim, Jeong Hun; Kim, Jin Cheon; Kim, Jin Hyoung; Kim, Kwang Woon; Kim, Michael D; Kim, Moon-Moo; Kim, Peter K; Kim, Seong Who; Kim, Soo-Youl; Kim, Yong-Sun; Kim, Yonghyun; Kimchi, Adi; Kimmelman, Alec C; Kimura, Tomonori; King, Jason S; Kirkegaard, Karla; Kirkin, Vladimir; Kirshenbaum, Lorrie A; Kishi, Shuji; Kitajima, Yasuo; Kitamoto, Katsuhiko; Kitaoka, Yasushi; Kitazato, Kaio; Kley, Rudolf A; Klimecki, Walter T; Klinkenberg, Michael; Klucken, Jochen; Knævelsrud, Helene; Knecht, Erwin; Knuppertz, Laura; Ko, Jiunn-Liang; Kobayashi, Satoru; Koch, Jan C; Koechlin-Ramonatxo, Christelle; Koenig, Ulrich; Koh, Young Ho; Köhler, Katja; Kohlwein, Sepp D; Koike, Masato; Komatsu, Masaaki; Kominami, Eiki; Kong, Dexin; Kong, Hee Jeong; Konstantakou, Eumorphia G; Kopp, Benjamin T; Korcsmaros, Tamas; Korhonen, Laura; Korolchuk, Viktor I; Koshkina, Nadya V; Kou, Yanjun; Koukourakis, Michael I; Koumenis, Constantinos; Kovács, Attila L; Kovács, Tibor; Kovacs, Werner J; Koya, Daisuke; Kraft, Claudine; Krainc, Dimitri; Kramer, Helmut; Kravic-Stevovic, Tamara; Krek, Wilhelm; Kretz-Remy, Carole; Krick, Roswitha; Krishnamurthy, Malathi; Kriston-Vizi, Janos; Kroemer, Guido; Kruer, Michael C; Kruger, Rejko; Ktistakis, Nicholas T; Kuchitsu, Kazuyuki; Kuhn, Christian; Kumar, Addanki Pratap; Kumar, Anuj; Kumar, Ashok; Kumar, Deepak; Kumar, Dhiraj; Kumar, Rakesh; Kumar, Sharad; Kundu, Mondira; Kung, Hsing-Jien; Kuno, Atsushi; Kuo, Sheng-Han; Kuret, Jeff; Kurz, Tino; Kwok, Terry; Kwon, Taeg Kyu; Kwon, Yong Tae; Kyrmizi, Irene; La Spada, Albert R; Lafont, Frank; Lahm, Tim; Lakkaraju, Aparna; Lam, Truong; Lamark, Trond; Lancel, Steve; Landowski, Terry H; Lane, Darius Jr; Lane, Jon D; Lanzi, Cinzia; Lapaquette, Pierre; Lapierre, Louis R; Laporte, Jocelyn; Laukkarinen, Johanna; Laurie, Gordon W; Lavandero, Sergio; Lavie, Lena; LaVoie, Matthew J; Law, Betty Yuen Kwan; Law, Helen Ka-Wai; Law, Kelsey B; Layfield, Robert; Lazo, Pedro A; Le Cam, Laurent; Le Roch, Karine G; Le Stunff, Hervé; Leardkamolkarn, Vijittra; Lecuit, Marc; Lee, Byung-Hoon; Lee, Che-Hsin; Lee, Erinna F; Lee, Gyun Min; Lee, He-Jin; Lee, Hsinyu; Lee, Jae Keun; Lee, Jongdae; Lee, Ju-Hyun; Lee, Jun Hee; Lee, Michael; Lee, Myung-Shik; Lee, Patty J; Lee, Sam W; Lee, Seung-Jae; Lee, Shiow-Ju; Lee, Stella Y; Lee, Sug Hyung; Lee, Sung Sik; Lee, Sung-Joon; Lee, Sunhee; Lee, Ying-Ray; Lee, Yong J; Lee, Young H; Leeuwenburgh, Christiaan; Lefort, Sylvain; Legouis, Renaud; Lei, Jinzhi; Lei, Qun-Ying; Leib, David A; Leibowitz, Gil; Lekli, Istvan; Lemaire, Stéphane D; Lemasters, John J; Lemberg, Marius K; Lemoine, Antoinette; Leng, Shuilong; Lenz, Guido; Lenzi, Paola; Lerman, Lilach O; Lettieri Barbato, Daniele; Leu, Julia I-Ju; Leung, Hing Y; Levine, Beth; Lewis, Patrick A; Lezoualc'h, Frank; Li, Chi; Li, Faqiang; Li, Feng-Jun; Li, Jun; Li, Ke; Li, Lian; Li, Min; Li, Min; Li, Qiang; Li, Rui; Li, Sheng; Li, Wei; Li, Wei; Li, Xiaotao; Li, Yumin; Lian, Jiqin; Liang, Chengyu; Liang, Qiangrong; Liao, Yulin; Liberal, Joana; Liberski, Pawel P; Lie, Pearl; Lieberman, Andrew P; Lim, Hyunjung Jade; Lim, Kah-Leong; Lim, Kyu; Lima, Raquel T; Lin, Chang-Shen; Lin, Chiou-Feng; Lin, Fang; Lin, Fangming; Lin, Fu-Cheng; Lin, Kui; Lin, Kwang-Huei; Lin, Pei-Hui; Lin, Tianwei; Lin, Wan-Wan; Lin, Yee-Shin; Lin, Yong; Linden, Rafael; Lindholm, Dan; Lindqvist, Lisa M; Lingor, Paul; Linkermann, Andreas; Liotta, Lance A; Lipinski, Marta M; Lira, Vitor A; Lisanti, Michael P; Liton, Paloma B; Liu, Bo; Liu, Chong; Liu, Chun-Feng; Liu, Fei; Liu, Hung-Jen; Liu, Jianxun; Liu, Jing-Jing; Liu, Jing-Lan; Liu, Ke; Liu, Leyuan; Liu, Liang; Liu, Quentin; Liu, Rong-Yu; Liu, Shiming; Liu, Shuwen; Liu, Wei; Liu, Xian-De; Liu, Xiangguo; Liu, Xiao-Hong; Liu, Xinfeng; Liu, Xu; Liu, Xueqin; Liu, Yang; Liu, Yule; Liu, Zexian; Liu, Zhe; Liuzzi, Juan P; Lizard, Gérard; Ljujic, Mila; Lodhi, Irfan J; Logue, Susan E; Lokeshwar, Bal L; Long, Yun Chau; Lonial, Sagar; Loos, Benjamin; López-Otín, Carlos; López-Vicario, Cristina; Lorente, Mar; Lorenzi, Philip L; Lõrincz, Péter; Los, Marek; Lotze, Michael T; Lovat, Penny E; Lu, Binfeng; Lu, Bo; Lu, Jiahong; Lu, Qing; Lu, She-Min; Lu, Shuyan; Lu, Yingying; Luciano, Frédéric; Luckhart, Shirley; Lucocq, John Milton; Ludovico, Paula; Lugea, Aurelia; Lukacs, Nicholas W; Lum, Julian J; Lund, Anders H; Luo, Honglin; Luo, Jia; Luo, Shouqing; Luparello, Claudio; Lyons, Timothy; Ma, Jianjie; Ma, Yi; Ma, Yong; Ma, Zhenyi; Machado, Juliano; Machado-Santelli, Glaucia M; Macian, Fernando; MacIntosh, Gustavo C; MacKeigan, Jeffrey P; Macleod, Kay F; MacMicking, John D; MacMillan-Crow, Lee Ann; Madeo, Frank; Madesh, Muniswamy; Madrigal-Matute, Julio; Maeda, Akiko; Maeda, Tatsuya; Maegawa, Gustavo; Maellaro, Emilia; Maes, Hannelore; Magariños, Marta; Maiese, Kenneth; Maiti, Tapas K; Maiuri, Luigi; Maiuri, Maria Chiara; Maki, Carl G; Malli, Roland; Malorni, Walter; Maloyan, Alina; Mami-Chouaib, Fathia; Man, Na; Mancias, Joseph D; Mandelkow, Eva-Maria; Mandell, Michael A; Manfredi, Angelo A; Manié, Serge N; 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    In: Autophagy, Vol. 12, No. 1, 02.01.2016, p. 1-222.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Interleukin 20 regulates dendritic cell migration and expression of co-stimulatory molecules. / Bech, Rikke; Jalilian, Babak; Agger, Ralf; Iversen, Lars; Erlandsen, Mogens; Otkjaer, Kristian; Johansen, Claus; Paludan, Søren R; Rosenberg, Carina A; Kragballe, Knud; Vorup-Jensen, Thomas.

    In: Molecular and Cellular Therapies, Vol. 4, No. 1, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. 2015
  32. Published

    Mutations in the TLR3 signaling pathway and beyond in adult patients with herpes simplex encephalitis. / Mørk, N; Kofod-Olsen, E; Sørensen, K B; Bach, E; Ørntoft, T F; Østergaard, Lars Jørgen; Paludan, S R; Christiansen, M; Mogensen, Trine.

    In: Genes and Immunity, Vol. 16, No. 8, 12.2015, p. 552-66.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    An innate antiviral pathway acting before interferons at epithelial surfaces. / Iversen, Marie B; Reinert, Line S; Thomsen, Martin K; Bagdonaite, Ieva; Nandakumar, Ramya; Cheshenko, Natalia; Prabakaran, Thaneas; Vakhrushev, Sergey Y; Krzyzowska, Malgosha; Kratholm, Sine K; Ruiz-Perez, Fernando; Petersen, Steen V; Goriely, Stanislas; Bibby, Bo Martin; Eriksson, Kristina; Ruland, Jürgen; Thomsen, Allan R; Herold, Betsy C; Wandall, Hans H; Frische, Sebastian; Holm, Christian K; Paludan, Søren R.

    In: Nature Immunology, 30.11.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Activation and regulation of DNA-driven immune responses. / Paludan, Søren R.

    In: Microbiology and Molecular Biology Reviews, Vol. 79, No. 2, 06.2015, p. 225-41.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Catching the adaptor-WDFY1, a new player in the TLR-TRIF pathway. / Nandakumar, Ramya; Paludan, Søren R.

    In: E M B O Reports, Vol. 16, No. 4, 04.2015, p. 397-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection. / Sun, Chenglong; Schattgen, Stefan A; Pisitkun, Prapaporn; Jorgensen, Joan P; Hilterbrand, Adam T; Wang, Lucas J; West, John A; Hansen, Kathrine; Horan, Kristy A; Jakobsen, Martin Roelsgaard; O'Hare, Peter; Adler, Heiko; Sun, Ren; Ploegh, Hidde L; Damania, Blossom; Upton, Jason W; Fitzgerald, Katherine A; Paludan, Søren R.

    In: Journal of Immunology, Vol. 194, No. 4, 15.02.2015, p. 1819-31.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Functional IRF3 deficiency in a patient with herpes simplex encephalitis. / Andersen, Line Lykke; Mørk, Nanna; Reinert, Line S; Kofod-Olsen, Emil; Narita, Ryo; Jørgensen, Sofie E; Skipper, Kristian A; Höning, Klara; Gad, Hans Henrik; Østergaard, Lars; Ørntoft, Torben F; Hornung, Veit; Paludan, Søren R; Mikkelsen, Jacob Giehm; Fujita, Takashi; Christiansen, Mette; Hartmann, Rune; Mogensen, Trine H.

    In: Journal of Experimental Medicine, Vol. 212, No. 9, 2015, p. 1371-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    Innate recognition of alphaherpesvirus DNA. / Luecke, Stefanie; Paludan, Søren R.

    In: Virus Research, Vol. 92, 2015, p. 63-100.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. 2014
  40. Published

    TRAM is required for TLR2 endosomal signaling to type I IFN induction. / Stack, Julianne; Doyle, Sarah L; Connolly, Dympna J; Reinert, Line S; O'Keeffe, Kate M; McLoughlin, Rachel M; Paludan, Søren R; Bowie, Andrew G.

    In: Journal of Immunology, Vol. 193, No. 12, 15.12.2014, p. 6090-102.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  41. Published

    A coding IRAK2 protein variant compromises Toll-like receptor (TLR) signaling and is associated with colorectal cancer survival. / Wang, Hui; Flannery, Sinead M; Dickhöfer, Sabine; Huhn, Stefanie; George, Julie; Kubarenko, Andriy V; Lascorz, Jesus; Bevier, Melanie; Willemsen, Joschka; Pichulik, Tica; Schafmayer, Clemens; Binder, Marco; Manoury, Bénédicte; Paludan, Søren R; Alarcon-Riquelme, Marta; Bowie, Andrew G; Försti, Asta; Weber, Alexander N R.

    In: Journal of Biological Chemistry, Vol. 289, No. 33, 15.08.2014, p. 23123-31.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway. / Hansen, Kathrine; Prabakaran, Thaneas; Laustsen, Anders; Jørgensen, Sofie E; Rahbek, Stine Hess; Jensen, Søren B; Nielsen, Rikke; Leber, Jess H; Decker, Thomas; Horan, Kristy A; Jakobsen, Martin R; Paludan, Søren R.

    In: E M B O Journal, Vol. 33, No. 15, 01.08.2014, p. 1654-66.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. Published

    IFI16 : At the interphase between innate DNA sensing and genome regulation. / Jakobsen, Martin Roelsgaard; Paludan, Søren R.

    In: Cytokine & Growth Factor Reviews, 21.06.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    Innate DNA sensing is impaired in HIV patients and IFI16 expression correlates to chronic immune activation. / Nissen, Sara K; Højen, Jesper Falkesgaard; Andersen, Karen L D; Kofod-Olsen, Emil; Berg, Randi K; Paludan, Søren R; Ostergaard, Lars; Jakobsen, Martin Roelsgaard; Tolstrup, Martin; Mogensen, Trine H.

    In: Clinical and Experimental Immunology, Vol. 177, No. 1, 05.03.2014, p. 295-309.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    Inflammatory Cytokines Break Down Intrinsic Immunological Tolerance of Human Primary Keratinocytes to Cytosolic DNA. / Chiliveru, Srikanth; Rahbek, Stine H; Jensen, Simon K; Jørgensen, Sofie E; Nissen, Sara K; Christiansen, Stig H; Mogensen, Trine H; Jakobsen, Martin R; Iversen, Lars; Johansen, Claus; Paludan, Søren R.

    In: Journal of Immunology, 2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    T Cells Detect Intracellular DNA but Fail to Induce Type I IFN Responses : Implications for Restriction of HIV Replication. / Berg, Randi K; Rahbek, Stine Hess; Kofod-Olsen, Emil; Holm, Christian K; Melchjorsen, Jesper; Jensen, David G.; Hansen, Anne Louise; Jørgensen, Louise B.; Østergaard, Lars Jørgen; Tolstrup, Martin; Larsen, Carsten S; Paludan, Søren R; Jakobsen, Martin R; Mogensen, Trine H.

    In: PLOS ONE, Vol. 9, No. 1, 2014, p. e84513.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. 2013
  48. Published

    IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication. / Jakobsen, Martin Roelsgaard; Bak, Rasmus O; Andersen, Annika; Berg, Randi K; Jensen, Søren B; Tengchuan, Jin; Laustsen, Anders; Hansen, Kathrine; Ostergaard, Lars; Fitzgerald, Katherine A; Xiao, T Sam; Mikkelsen, Jacob G; Mogensen, Trine H; Paludan, Søren R.

    In: Proceedings of the National Academy of Sciences of the United States of America, 23.10.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  49. Published

    Proteasomal Degradation of Herpes Simplex Virus Capsids in Macrophages Releases DNA to the Cytosol for Recognition by DNA Sensors. / Horan, Kristy A; Hansen, Kathrine; Jakobsen, Martin Roelsgaard; Holm, Christian K; Søby, Stine; Unterholzner, Leonie; Thompson, Mikayla; West, John A; Iversen, Marie B; Rasmussen, Simon B; Ellermann-Eriksen, Svend; Kurt-Jones, Evelyn; Landolfo, Santo; Damania, Blossom; Melchjorsen, Jesper; Bowie, Andrew G; Fitzgerald, Katherine A; Paludan, Søren R.

    In: Journal of Immunology, Vol. 190, No. 5, 01.03.2013, p. 2311-2329.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    Interleukin-21 Receptor Signalling Is Important for Innate Immune Protection against HSV-2 Infections. / Kratholm, Sine K; Iversen, Marie B; Reinert, Line; Jensen, Simon K; Hokland, Marianne; Andersen, Thomas; Rankin, Andrew; Young, Deborah; Frische, Sebastian; Paludan, Søren R; Holm, Christian K.

    In: PLOS ONE, Vol. 8, No. 12, 2013, p. e81790.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. 2012
  52. Published

    The crystal structure of the interleukin 21 receptor bound to interleukin 21 reveals that a sugar chain interacting with the WSXWS motif is an integral part of the interleukin 21 receptor. / Hamming, Ole Jensen; Kang, Lishan; Svensson, Anders; Karlsen, Jesper Lykkegaard; Rahbek-Nielsen, Henrik; Paludan, Søren Riis; Hjorth, Siv A; Bondensgaard, Kent; Hartmann, Rune.

    In: Journal of Biological Chemistry, Vol. 287, 16.03.2012, p. 9454-9460.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Antiviral and immunological effects of tenofovir microbicide in vaginal herpes simplex virus 2 infection. / Vibholm, Line; Reinert, Line S; Søgaard, Ole S; Paludan, Søren R; Østergaard, Lars Jørgen; Tolstrup, Martin; Melchjorsen, Jesper.

    In: AIDS Research and Human Retroviruses, Vol. 28, No. 11, 2012, p. 1404-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  54. Published

    Caught in translation : innate restriction of HIV mRNA translation by a schlafen family protein. / Jakobsen, Martin Roelsgaard; Mogensen, Trine H; Paludan, Søren R.

    In: Cell Research, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  55. Published

    Differential impact of interferon regulatory factor 7 in the initiation of the type I interferon response in the LCMV infected CNS versus the periphery. / Christensen, Jeanette Erbo; Fenger, Christina; Issazadeh-Navikas, Shohreh; Krug, Anna; Liljestrøm, Peter; Goriely, Stanislas; Paludan, Søren Riis; Finsen, Bente; Christensen, Jan Pravsgaard; Thomsen, Allan Randrup.

    In: Indian Journal of Virology, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  56. Published

    Genomic HIV RNA Induces Innate Immune Responses through RIG-I-Dependent Sensing of Secondary-Structured RNA. / Berg, Randi K; Melchjorsen, Jesper; Rintahaka, Johanna; Diget, Elisabeth; Søby, Stine; Horan, Kristy A; Gorelick, Robert J; Matikainen, Sampsa; Larsen, Carsten S; Østergaard, Lars Jørgen; Paludan, Søren R; Mogensen, Trine H.

    In: P L o S One, Vol. 7, No. 1, 2012, p. e29291.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. Published

    Mitochondria-derived reactive oxygen species negatively regulates immune innate signaling pathways triggered by a DNA virus, but not by an RNA virus. / Gonzalez-Dosal, Regina; Horan, Kristy A; Paludan, Søren Riis.

    In: Biochemical and Biophysical Research Communications, Vol. 418, No. 4, 2012, p. 806-10.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  58. Published

    Pattern recognition receptor responses in children with chronic hepatitis B virus infection. / Heiberg, Ida Louise; Winther, Thilde Nordmann; Paludan, Søren Riis; Hogh, Birthe.

    In: Journal of Clinical Virology, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  59. Published

    TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice. / Reinert, Line S; Harder, Louis; Holm, Christian K; Iversen, Marie Beck; Horan, Kristy A; Dagnæs-Hansen, Frederik; Ulhøi, Benedicte P; Holm, Thomas H; Mogensen, Trine H; Owens, Trevor; Nyengaard, Jens R; Thomsen, Allan Randrup; Paludan, Søren Riis.

    In: Journal of Clinical Investigation, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  60. Published

    TLR9-adjuvanted pneumococcal conjugate vaccine induces antibody-independent memory responses in HIV-infected adults. / Offersen, Rasmus; Melchjorsen, Jesper; Paludan, Søren R; Østergaard, Lars Jørgen; Tolstrup, Martin; Søgaard, Ole S.

    In: Human Vaccines & Immunotherapeutics, Vol. 8, No. 8, 2012, p. 1042-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  61. Published

    Type III IFNs : new layers of complexity in innate antiviral immunity. / Ank, Nina; Paludan, Søren Riis.

    In: BioFactors, Vol. 35, No. 1, 2012, p. 82-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  62. Published

    Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING. / Holm, Christian K; Jensen, Søren B; Jakobsen, Martin Roelsgaard; Cheshenko, Natalia; Horan, Kristy A; Moeller, Hanne B; Gonzalez-Dosal, Regina; Rasmussen, Simon B; Christensen, Maria H; Yarovinsky, Timur O; Rixon, Frazer J; Herold, Betsy C; Fitzgerald, Katherine A; Paludan, Søren R.

    In: Nature Immunology, Vol. 13, No. 8, 2012, p. 737-43.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  63. 2011
  64. Published

    Tenofovir selectively regulates production of inflammatory cytokines and shifts the IL-12 / IL-10 balance in human primary cells. / Melchjorsen, Jesper; Risør, Michael W; Søgaard, Ole S; Oʼloughlin, Kieran L; Chow, Sue; Paludan, Søren R; Ellermann-Eriksen, Svend; Hedley, David W; Phd, Hans Minderman; Østergaard, Lars Jørgen; Tolstrup, Martin.

    In: J A I D S, Vol. 57, No. 4, 05.04.2011, p. 265-275.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  65. Published

    Activation and receptor studies of human mast cells in healthy individuals and patients with asthma and allergy. / Schiøtz, Peter Oluf; Frandsen, Pernille Munk; Paludan, Søren Riis.

    2011. Poster session presented at Britishc Society of Immunology Summerschool, Llantwit Major, Wales, United Kingdom.

    Research output: Contribution to conferencePosterResearchpeer-review

  66. Published

    Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes. / Rasmussen, Simon B; Horan, Kristy A; Holm, Christian K; Stranks, Amanda J; Mettenleiter, Thomas C; Simon, A Katharina; Jensen, Søren B; Rixon, Frazer J; He, Bin; Paludan, Søren Riis.

    In: Journal of Immunology, Vol. 187, No. 10, 2011, p. 5268-76.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  67. Published

    HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6. / Dosal, Regina Gonzalez; Horan, Kristy A; Rahbek, Stine H; Ichijo, Hidenori; Chen, Zhijian J; Mieyal, John J; Hartmann, Rune; Paludan, Søren R.

    In: P L o S Pathogens, Vol. 7, No. 9, 2011, p. e1002250.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  68. Published

    IgE in Culture Medium Influences the Activation of Human Mast Cells. / Schiøtz, Peter Oluf; Frandsen, Pernille Munk; Paludan, Søren Riis.

    2011. Poster session presented at Dansk Selskab for Allergologi, Årsmøde 2011, Kolding, .

    Research output: Contribution to conferencePosterResearchpeer-review

  69. Published

    Recognition of herpesviruses by the innate immune system. / Paludan, Søren Riis; Bowie, Andrew G; Horan, Kristy A; Fitzgerald, Katherine A.

    In: Nature Reviews. Immunology, Vol. 11, No. 2, 2011, p. 143-54.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  70. Published

    Toll2011 at Lago di Garda : studying danger sensors by the guard towers at the lake. / Paludan, Søren Riis; Levy, Ofer; Bowie, Andrew G.

    In: Nature Immunology, Vol. 12, No. 9, 2011, p. 805-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  71. 2010
  72. Published

    Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity. / Kristiansen, Helle; Scherer, Christina A; McVean, Maralee; Iadonato, Shawn P; Vends, Susanne; Thavachelvam, Karthiga; Steffensen, Thomas B; Horan, Kristy A; Kuri, Thomas; Weber, Friedemann; Paludan, Søren R; Hartmann, Rune.

    In: Journal of Virology, Vol. 84, No. 22, 01.11.2010, p. 11898-904.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  73. Published

    IFI16 is an innate immune sensor for intracellular DNA. / Unterholzner, Leonie; Keating, Sinead E; Baran, Marcin; Horan, Kristy A; Jensen, Søren B; Sharma, Shruti; Sirois, Cherilyn M; Jin, Tengchuan; Latz, Eicke; Xiao, T Sam; Fitzgerald, Katherine A; Paludan, Søren R; Bowie, Andrew G.

    In: Nature Immunology, Vol. 11, No. 11, 01.11.2010, p. 997-1004.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  74. Published

    Mechanisms of type III interferon expression. / Iversen, Marie Beck; Paludan, Søren R.

    In: Journal of Interferon & Cytokine Research, Vol. 30, No. 8, 01.08.2010, p. 573-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  75. Published

    Expression of type III interferon (IFN) in the vaginal mucosa is mediated primarily by dendritic cells and displays stronger dependence on NF-kappaB than type I IFNs. / Iversen, Marie Beck; Ank, Nina; Melchjorsen, Jesper; Paludan, Søren R.

    In: Journal of Virology, Vol. 84, No. 9, 05.2010, p. 4579-86.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  76. Published

    Innate immune recognition and activation during HIV infection. / Mogensen, Trine H; Melchjorsen, Jesper; Larsen, Carsten S; Paludan, Søren R.

    In: Retrovirology, Vol. 7, 01.01.2010, p. 54.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  77. Published

    Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways. / Melchjorsen, Jesper; Rintahaka, Johanna; Søby, Stine; Horan, Kristy A; Poltajainen, Alina; Østergaard, Lars; Paludan, Søren R; Matikainen, Sampsa.

    In: Journal of Virology, Vol. 84, No. 21, 2010, p. 11350-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  78. Published

    Induction of interferon-stimulated genes by Chlamydia pneumoniae in fibroblasts is mediated by intracellular nucleotide-sensing receptors. / Chiliveru, Srikanth; Birkelund, Svend; Paludan, Søren R.

    In: P L o S One, Vol. 5, No. 4, 2010, p. e10005.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  79. Published

    Recognition of Herpes Simplex Virus by Human Macrophages via Non-Toll Recognition Receptors - Impact on both Inflammatory and Interferon Genes. / Melchjorsen, Jesper; Rintakaha, Johanna; Østergaard, Lars Jørgen; Paludan, Søren Riis; Matikainen, Sampsa.

    2010. Poster session presented at 26th Annual Meeting of the Scandinavian Society for Antimicrobial Chemotherapy, Tromsø, Norway.

    Research output: Contribution to conferencePosterResearch

  80. Published

    The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA. / Otkjaer, Kristian; Holtmann, Helmut; Kragstrup, Tue Wenzel; Paludan, Søren Riis; Johansen, Claus; Gaestel, Matthias; Kragballe, Knud; Iversen, Lars.

    In: P L o S One, Vol. 5, No. 1, 2010, p. e8671.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  81. 2009
  82. Published

    Activation and Evasion of Innate Antiviral Immunity by Herpes Simplex Virus. / Melchjorsen, Jesper; Matikainen, Sampsa; Paludan, Søren Riis.

    In: Viruses, 05.11.2009, p. 737-759.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  83. Published

    Innate recognition of intracellular pathogens: detection and activation of the first line of defense. / Rasmussen, Simon B; Reinert, Line; Paludan, Søren R.

    In: A P M I S Supplementum, Vol. 117, No. 5-6, 01.05.2009, p. 323-37.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  84. Published

    Herpes simplex virus infection is sensed by both Toll-like receptors and retinoic acid-inducible gene- like receptors, which synergize to induce type I interferon production. / Rasmussen, Simon B; Jensen, Søren B; Nielsen, Christoffer; Quartin, Emanuel; Kato, Hiroki; Chen, Zhijian J; Silverman, Robert H; Akira, Shizuo; Paludan, Søren R.

    In: Journal of General Virology, Vol. 90, No. Pt 1, 01.01.2009, p. 74-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  85. Published

    Activation and evasion of innate antiviral immunity by herpes simplex virus. / Melchjorsen, Jesper; Matikainen, Sampsa; Paludan, Søren Riis.

    In: Viruses, Vol. 1, No. 3, 2009, p. 737-59.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  86. Published

    Differential Regulation of the OASL and OAS1 Genes in Response to Viral Infections. / Melchjorsen, Jesper; Kristiansen, Helle; Christiansen, Rune; Rintahaka, Johanna; Matikainen, Sampsa; Paludan, Søren R; Hartmann, Rune.

    In: Journal of Interferon & Cytokine Research, 2009.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  87. Published

    Differential regulation of OASL and OAS1 genes in response to viral infections : Virus induction of OASL. / Kristiansen, Helle; Melchjorsen, Jesper; Christiansen, Rune; Rintahaka, Johanna; Matikainen, Sampsa; Paludan, Søren Riis; Hartmann, Rune.

    2009. Poster session presented at Cytokines 2008, Montreal, Canada.

    Research output: Contribution to conferencePosterResearch

  88. Published

    Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice. / Koenen, Rory R; von Hundelshausen, Philipp; Nesmelova, Irina V; Zernecke, Alma; Liehn, Elisa A; Sarabi, Alisina; Kramp, Birgit K; Piccinini, Anna M; Paludan, Søren Riis; Kowalska, M Anna; Kungl, Andreas J; Hackeng, Tilman M; Mayo, Kevin H; Weber, Christian.

    In: Nature Medicine, Vol. 15, No. 1, 2009, p. 97-103.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  89. Published

    Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice. / Koenen, RR; Hundelshausen, P; Nesmelova, IV; Zernecke, A; Liehn, EA; Sarabi, A; Kramp, BK; Piccinini, AM; Paludan, Søren Riis; Kowalska, MA; Kungl, A; Hackeng, TM; Mayo, KH; Weber, C.

    In: Nature Medicine, Vol. 15, 2009, p. 97-103.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  90. Published

    Divergent effects of Tenofovir and Retrovir (AZT) on TLR-mediated cytokine production. / Melchjorsen, Jesper; Tolstrup, Martin; Paludan, Søren Riis; Østergaard, Lars Jørgen.

    2009. Poster session presented at The 25th Annual Meeting of the Scandinavian Society for Antimicrobial Chemotherapy, København, Denmark.

    Research output: Contribution to conferencePosterResearch

  91. Published

    Herpes simplex virus infection is sensed by both Toll-like receptors and retinoic acid-inducible gene- like receptors, which synergize to induce type I interferon production. / Rasmussen, Simon Brandtoft; Jensen, Søren B; Nielsen, C; Quartin, E; Kato, H; Chen, ZJ; Silverman, RH; Akira, S; Paludan, Søren Riis.

    In: Journal of General Virology, Vol. 90, 2009, p. 74-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  92. Published

    Innate Recognition of Herpes Simplex Virus by Human Primary Macrophages is mediated by Intracellular Pattern Recognition Receptors. / Melchjorsen, Jesper; Rintahaka, Johanna; Østergaard, Lars Jørgen; Julkunen, Ilkka; Paludan, Søren Riis.

    2009. Poster session presented at 2009 Joint Meeting of the International Cytokine Society, the International Society for Interferon and Cytokine Research and the Society of Leukocyte Biology., Lisabon, Portugal.

    Research output: Contribution to conferencePosterResearch

  93. Published

    Interferon-{lambda} Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family. / Gad, Hans Henrik; Dellgren, Christoffer; Hamming, Ole J; Vends, Susanne; Paludan, Søren Riis; Hartmann, Rune.

    In: Journal of Biological Chemistry, Vol. 284, No. 31, 2009, p. 20869-75.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  94. Published

    RIG-I-mediated activation of p38 MAPK is essential for viral induction of interferon and activation of dendritic cells: dependence on TRAF2 and TAK1. / Mikkelsen, Susie S; Jensen, Søren B; Chiliveru, Srikanth; Melchjorsen, Jesper; Julkunen, Ilkka; Gaestel, Matthias; Arthur, J Simon C; Flavell, Richard A; Ghosh, Sankar; Paludan, Søren R.

    In: Journal of Biological Chemistry, Vol. 284, No. 16, 2009, p. 10774-82.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  95. Published

    TLR3 Ligand Polyinosinic:Polycytidylic Acid Induces IL-17A and IL-21 Synthesis in Human Th Cells. / Holm, Christian; Petersen, Charlotte C; Hvid, Malene; Petersen, Line; Paludan, Søren R; Deleuran, Bent; Hokland, Marianne.

    In: Journal of Immunology, Vol. 183, 2009, p. 4422-31.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  96. 2008
  97. Published

    An Important Role for Type III Interferon (IFN-l/IL-28) in TLR-Induced Antiviral Activity. / Ank, Nina; Iversen, Marie Beck; Bartholdy, Christina; Staeheli, Peter; Hartmann, Rune; Jensen, Uffe Birk; Dagnæs-Hansen, Frederik; Thomsen, Allan; Chen, Zhi; Haugen, Harald; Klucher, Kevin; Paludan, Søren Riis.

    In: Journal of Immunology, Vol. 180, No. 4, 15.02.2008, p. 2474-2485.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  98. Published

    An important role for type III interferon (IFN-λ/IL-28) in TLR-induced antiviral activity. / Ank, Nina; Iversen, Marie B.; Bartholdy, Christina; Staeheli, Peter; Hartmann, Rune; Jensen, Uffe B.; Dagnaes-Hansen, Frederik; Thomsen, Allan R.; Chen, Zhi; Haugen, Harald; Klucher, Kevin; Paludan, Søren R.

    In: Journal of Immunology, Vol. 180, No. 4, 15.02.2008, p. 2474-2485.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  99. Published

    Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model. / Howard, Kenneth Alan; Paludan, Søren R; Behlke, Mark A; Besenbacher, Flemming; Deleuran, Bent Winding; Kjems, Jørgen.

    In: Molecular Therapy, Vol. 17, No. 1, 2008, p. 162-168.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  100. Published

    Delivery of siRNA from lyophilized polymeric surfaces. / Andersen, Morten Ø; Howard, Kenneth A; Paludan, Søren R; Besenbacher, Flemming; Kjems, Jørgen.

    In: Biomaterials, Vol. 29, No. 4, 2008, p. 506-512.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  101. Published

    Important role for Toll-like receptor 9 in host defense against meningococcal sepsis. / Sjölinder, Hong; Mogensen, Trine H; Kilian, Mogens; Jonsson, Ann-Beth; Paludan, Søren R.

    In: Infection and Immunity, Vol. 76, No. 11, 2008, p. 5421-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  102. Published

    Important role for Toll-like receptor 9 in host defense against meningococcal sepsis. / Sjölinder, Hong; Mogensen, Trine; Kilian, Mogens; Jonsson, Ann-Beth; Paludan, Søren Riis.

    In: Infection and Immunity, Vol. 76, 2008, p. 5421-5428.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  103. Published

    Interferon-lambda contributes to innate immunity of mice against influenza A virus but not against hepatotropic viruses. / Mordstein, M; Kochs, G; Dumoutier, L; Renauld, JC; Paludan, Søren Riis; Klucher, K; Staeheli, P.

    In: P L o S Pathogens, Vol. 4, 2008, p. e1000151.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  104. Published

    Mechanisms of dexamethasone-mediated inhibition of Toll-like receptor signaling induced by Neisseria meningitidis and Streptococcus pneumoniae. / Mogensen, Trine; Berg, Randi S; Paludan, Søren R; Østergaard, Lars.

    In: Infection and Immunity, Vol. 76, No. 1, 2008, p. 189-97.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  105. Published

    Streptococcus pneumoniae stabilizes tumor necrosis factor alpha mRNA through a pathway dependent on p38 MAPK but independent of Toll-like receptors. / Mogensen, Trine; Berg, Randi; Østergaard, Lars; Paludan, Søren Riis.

    In: B M C Immunology, Vol. 9, No. 1, 2008, p. 52.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  106. Published

    TLR-mediated NF-kB-dependent cytokine production is differently affected by HIV therapeutics. / Melchjorsen, Jesper; Paludan, Søren Riis; Mogensen, Trine; Tolstrup, Martin; Østergaard, Lars Jørgen.

    2008. Poster session presented at Toll2008 meeting, Lissabon, Portugal.

    Research output: Contribution to conferencePosterResearch

  107. Published

    TLR2 and TLR9 Synergistically Control Herpes Simplex Virus Infection in the Brain. / Sørensen, Louise Nørgaard; Reinert, Line; Malmgaard, Lene; Bartholdy, Christina; Thomsen, Allan Randrup; Paludan, Søren Riis.

    In: Journal of Immunology, Vol. 181, 2008, p. 8604-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  108. Published

    TLR2 and TLR9 synergistically control herpes simplex virus infection in the brain. / Sørensen, Louise N; Reinert, Line S; Malmgaard, Lene; Bartholdy, Christina; Thomsen, Allan Randrup; Paludan, Søren Riis.

    In: Journal of Immunology, Vol. 181, No. 12, 2008, p. 8604-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  109. Published

    The p59 oligoadenylate synthetase-like protein possesses antiviral activity that requires the C-terminal ubiquitin-like domain. / Marques, Joao; Anwar, Jangawar; Eskildsen-Larsen, Signe; Rebouillat, Dominique; Paludan, Søren Riis; Sen, Ganes; Williams, Bryan R G; Hartmann, Rune.

    In: Journal of General Virology, Vol. 89, No. Pt 11, 2008, p. 2767-72.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  110. 2007
  111. Published

    Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases. / Zhou, Zhangle; Hamming, Ole J; Ank, Nina; Paludan, Søren R; Nielsen, Anders L; Hartmann, Rune; Nielsen, Anders Lade.

    In: Journal of Virology, Vol. 81, No. 14, 01.07.2007, p. 7749-7758.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  112. Published

    Surface delivery of siRNA for implants. / Andersen, Morten Østergaard; Nygaard, Jens Vinge; Howard, Ken; Bak, Rasmus Otkjær; Paludan, Søren Riis; Raarup, Merete krog; Besenbacher, Flemming; Kjems, Jørgen.

    In: European Cells & Materials, Vol. 14, No. 3, 2007, p. 118.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  113. Published

    Toll-like receptorer, nye behandlingsstrategier? / Pedersen, Claus Vinter Bødker; Østergaard, Lars; Mogensen, Trine; Paludan, Søren Riis; Bertelsen, Lone Skovbo.

    In: Ugeskrift for Laeger, Vol. 169, No. 23, 2007, p. 2193-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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