Søren Kragh Moestrup

Soluble macrophage-derived CD163: a homogenous ectodomain protein with a dissociable haptoglobin-hemoglobin binding

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The soluble form of the haptoglobin-hemoglobin (Hp-Hb) scavenger receptor (sCD163) is a specific plasma/serum marker for macrophage activity. Here, we have characterized molecular forms in serum and investigated a role of sCD163 as a binder of Hp-Hb complexes.
Original languageEnglish
JournalImmunobiology
Volume215
Issue5
Pages (from-to)406-12
Number of pages7
ISSN0171-2985
DOIs
Publication statusPublished - 2010

    Research areas

  • Animals, Antigens, CD, Antigens, Differentiation, Myelomonocytic, CHO Cells, Cricetinae, Cricetulus, Haptoglobins, Hemoglobins, Humans, Ligands, Macrophages, Protein Binding, Protein Interaction Domains and Motifs, Protein Structure, Tertiary, Receptors, Cell Surface, Recombinant Proteins, Solubility

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