Søren Kragh Moestrup

  1. 2001
  2. Published

    Identification of the haemoglobin scavenger receptor. / Madsen, Mette; Graversen, J. H.; Jacobsen, Christian; Sonne, Ole; Hoffmann, H.-J.; Law, S. K. A.; Moestrup, Søren Kragh.

    In: Nature, Vol. 409, 2001, p. 198-201.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia. / Kozyraki, R.; Fyfe, J.; Verroust, P.J.; Jacobsen, Christian; Dautry-Varsat, A.; Gburek, J.; Willnow, T.E.; Christensen, Erik Ilsø; Moestrup, Søren Kragh.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, 2001, p. 12491-12496.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. 2000
  5. Published

    Cubilin P1297L mutation associated with hereditary megaloblastic anemia 1 causes impaired recognition of intrinsic factor-vitamin B(12) by cubilin. / Kristiansen, M; Aminoff, M; Jacobsen, Christian; de La Chapelle, A; Krahe, R; Verroust, P J; Moestrup, Søren Kragh.

    In: Blood, Vol. 96, No. 2, 2000, p. 405-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Cubilin and megalin mediated uptake of albumin in cultured proximal tubule cells of Opossum kidney. / Zhai, Xiao Yue; Nielsen, Rikke; Birn, Henrik; Drumm, K.; Mildenberger, S.; Freudinger, R.; Moestrup, Søren Kragh; Verroust, P.J.; Christensen, Erik Ilsø; Gekle, M.

    In: Kidney International, Vol. 58, 2000, p. 1523-1533.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Cubilin is an albumin binding protein important for renal tubular albumin reabsorption. / Birn, Henrik; Fyfe, J.C.; Jacobsen, Christian; Mounier, F.; Verroust, P.J.; Ørskov, Hans; Willnow, T.E.; Moestrup, Søren Kragh; Christensen, Erik Ilsø.

    In: J. Clin. Invest., Vol. 105, 2000, p. 1353-1361.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Evidence for the role of megalin in renal reabsorption of transthyretin. / Sousa, M.M.; Norden, A.G.; Jacobsen, Christian; Willnow, T.E.; Christensen, Erik Ilsø; Verroust, P.J.; Moestrup, Søren Kragh; Saraiva, M.J.

    In: Journal of Biological Chemistry, Vol. 275, 2000, p. 38176-38181.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Identification of the minimal functional unit in the low density lipoprotein receptor-related protein for binding the receptor-associated protein (RAP). / Andersen, O.M.; Christensen, L.L.; Christensen, P.A.; Sørensen, E.S.; Jacobsen, Christian; Moestrup, Søren Kragh; Etzerodt, M.; Thøgersen, H.C.

    In: Journal of Biological Chemistry, Vol. 275, No. 28, 2000, p. 21017-21024.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Mutational analysis of affinity and selectivity of kringle-tetranectin interaction : Grafting novel kringle affinity onto the tetranectin scaffold. / Graversen, J.H.; Jacobsen, Christian; Sigurskjold, B.W.; Lorentzen, R.H.; Moestrup, Søren Kragh; Thøgersen, H.C.; Etzerodt, M.

    In: Journal of Biological Chemistry, Vol. 275, No. 48, 2000, p. 37390-37396.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Physiopathological role of cubilin and megalin. / Verroust, P.J.; Kozyraki, R.; Hammond, T.G.; Moestrup, Søren Kragh; Christensen, Erik Ilsø.

    Advances in Nephrology. ed. / Grünfeld; Kreis; Bach; Maxwell. Mosby, 2000. p. 127-145.

    Research output: Contribution to book/anthology/report/proceedingReview

  12. Published

    Receptor associated protein is important for normal processing of megalin in kidney proximal tubules. / Birn, Henrik; Vorum, Henrik; Verroust, P.J.; Moestrup, Søren Kragh; Christensen, Erik Ilsø.

    In: Journal of the American Society of Nephrology, Vol. 11, 2000, p. 191-202.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Rôle physiopathologique de la cubilin et de la mégalin. / Verroust, P.J.; Kozyraki, R.; Hammond, T.G.; Moestrup, Søren Kragh; Christensen, Erik Ilsø.

    Actualités Néphrologiques 2000 de l`Hôpital Necker. ed. / J.P. Grünfeld. Flammarion, 2000. p. 271-285.

    Research output: Contribution to book/anthology/report/proceedingReview

  14. Published

    Specific binding of α-macroglobulin to complement-type repeat CR4 of the low-density lipoprotein receptor-related protein. / Andersen, O.M.; Christensen, P.A.; Christensen, L.L.; Jacobsen, Christian; Moestrup, Søren Kragh; Etzerodt, M.; Thøgersen, H.C.

    In: Biochemistry, Vol. 39, No. 35, 2000, p. 10627-10633.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. 1999
  16. Published

    Evidence for an essential role of megalin in transepithelial transport of retinol. / Christensen, Erik Ilsø; Moskaug, J.Ø.; Vorum, Henrik; Jacobsen, Christian; Gundersen, T.E.; Nykjær, Anders; Blomhoff, R.; Willnow, T.E.; Moestrup, Søren Kragh.

    In: Journal of the American Society of Nephrology, Vol. 10, 1999, p. 685-695.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Megalin antagonizes activation of the parathyroid hormone receptor. / Hilpert, J; Nykjær, Anders; Jacobsen, Christian; Wallukat, G; Nielsen, Rikke; Moestrup, Søren Kragh; Haller, H; Luft, F.C.; Christensen, Erik Ilsø; Willnow, T.E.

    In: Journal of Biological Chemistry, Vol. 274, 1999, p. 5620-5625.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Molecular dissection of the intrinsic factor-vitamin B12 receptor, cubilin, discloses regions important for membrane association and ligand binding. / Kristiansen, M; Kozyraki, R; Jacobsen, Christian; Nexø, E; Verroust, P J; Moestrup, S K.

    In: Journal of Biological Chemistry, Vol. 274, No. 29, 1999, p. 20540-4.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Mutations in CUBN, encoding the intrinsic factor-vitamin B12 receptor, cubilin, cause hereditary megaloblastic anaemia 1. / Aminoff, M.; Carter, J.E.; Chadwick, R.B.; Johnson, C.; Gräsbeck, R.; Abdelaal, M.A.; Broch, H.; Jenner, Lasse Bohl; Verroust, P.J.; Moestrup, Søren Kragh; Chapelle, A.; Krahe, R.

    In: Nature Genetics, Vol. 21, 1999, p. 309-313.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  20. Published

    Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding. / Petersen, Claus Munck; Nielsen, Morten Schallburg; Jacobsen, Christian; Tauris, Jacob; Jacobsen, L.; Gliemann, Jørgen; Moestrup, Søren Kragh; Madsen, Peder Søndergaard.

    In: E M B O Journal, Vol. 18, 1999, p. 595-604.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    The intrinsic factor-vitamin B12 receptor, cubilin, is a novel high affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein. / Kozyraki, R.; Fyfe, J.; Kristiansen, M.; Gerdes, C.; Jacobsen, Christian; Cui, S.; Christensen, Erik Ilsø; Aminoff, M.; De La Chapelle, A.; Krahe, R.; Moestrup, Søren Kragh.

    In: Nature Medicine, Vol. 5, 1999, p. 656-661.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. 1998
  23. Published

    The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins. / Moestrup, S K; Kozyraki, R; Madsen, M; Kaysen, J H; Rasmussen, H H; Brault, D; Pontillon, F; Goda, F O; Christensen, E I; Hammond, T G; Verroust, P J.

    In: The Journal of biological chemistry, Vol. 273, No. 9, 27.02.1998, p. 5235-42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Activation of 2'-5' oligoadenylate synthetase by single-stranded and double-stranded RNA aptamers. / Hartmann, R; Norby, P L; Martensen, P M; Jorgensen, P; James, M C; Jacobsen, Christian; Moestrup, S K; Clemens, M J; Justesen, J.

    In: Journal of Biological Chemistry, Vol. 273, No. 6, 1998, p. 3236-46.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Characterization of a kidney proximal tubule cell line, LLCPK1, expressing endocytotic active megalin. / Nielsen, Rikke; Birn, Henrik; Moestrup, S.K.; Nielsen, M.S.; Verroust, P; Christensen, Erik Ilsø.

    In: Journal of the American Society of Nephrology, Vol. 9, 1998, p. 1767-1776.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Megalin mediated endocytosis in renal proximal tubule. / Christensen, Erik Ilsø; Birn, Henrik; Verroust, P.; Moestrup, Søren Kragh.

    In: Renal Failure, Vol. 20, 1998, p. 191-199.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  27. Published

    Membrane receptors for endocytosis in renal proximal tubule. / Christensen, Erik Ilsø; Birn, Henrik; Verroust, P.; Moestrup, Søren Kragh.

    In: Int. Rev. Cytol., Vol. 180, 1998, p. 237-284.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  28. Published

    Sortilin is the major 110-kDa protein in GLUT4 vesicles from adipocytes. / Morris, N J; Ross, Steven; Lane, W S; Moestrup, S K; Petersen, C M; Keller, Søren; Lienhard, G E.

    In: Journal of Biological Chemistry, Vol. 273, No. 6, 1998, p. 3582-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    The carboxy-terminal domain of the receptor-associated protein binds to the Vps10p domain of sortilin. / Tauris, Jacob; Ellgaard, L.; Jacobsen, Christian; Nielsen, Morten Schallburg; Madsen, Peder Søndergaard; Thøgersen, Hans Christian; Gliemann, Jørgen; Petersen, Claus Munck; Moestrup, Søren Kragh.

    In: F E B S Letters, Vol. 429, No. 1, 1998, p. 27-30.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review