Søren Kragh Moestrup

  1. 2013
  2. Published

    CD163 binding to haptoglobin-hemoglobin complexes involves a dual-point electrostatic receptor-ligand pairing. / Nielsen, Marianne Jensby; Andersen, Christian Brix Folsted; Moestrup, Søren Kragh.

    In: Journal of Biological Chemistry, Vol. 288, No. 26, 28.06.2013, p. 18834-41.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Haptoglobin : the hemoglobin detoxifier in plasma. / Alayash, Abdu I; Andersen, Christian Brix Folsted; Moestrup, Søren Kragh; Bülow, Leif.

    In: Trends in Biotechnology, Vol. 31, No. 1, 01.2013, p. 2-3.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    CD163 and inflammation : Biological, diagnostic and therapeutic aspects. / Etzerodt, Anders; Moestrup, Søren Kragh.

    In: Antioxidants & Redox Signaling, Vol. 18, No. 17, 2013, p. 2352-2363.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Is classical pseudoxanthoma elasticum a consequence of hepatic ‘intoxication’ due to ABCC6 substrate accumulation in the liver? / Rasmussen, Mie Rostved; Sommerlund, Mette; Moestrup, Søren Kragh.

    In: Expert Review of Endocrinology & Metabolism, Vol. 8, No. 1, 2013, p. 37-46.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Plasma clearance of hemoglobin and haptoglobin in mice and effect of CD163 gene targeting disruption. / Etzerodt, Anders; Kjolby, Mads; Nielsen, Marianne Jensby; Maniecki, Maciej Bogdan; Svendsen, Pia; Moestrup, Søren Kragh.

    In: Antioxidants & Redox Signaling, Vol. 18, No. 17, 2013, p. 2254-2263.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    The Haptoglobin-CD163-Heme Oxygenase-1 Pathway for Hemoglobin Scavenging. / Thomsen, Jens Haugbølle; Etzerodt, Anders; Svendsen, Pia; Moestrup, Søren K.

    In: Oxidative Medicine and Cellular Longevity, Vol. 2013, 2013, p. 523652.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. 2012
  9. Published

    Tumor-promoting macrophages induce the expression of the macrophage-specific receptor CD163 in malignant cells. / Maniecki, Maciej Bogdan; Etzerodt, Anders; Ulhøi, Benedicte Parm; Steiniche, Torben; Borre, Michael; Andersen, Lars Dyrskjøt; Orntoft, Torben Falck; Moestrup, Søren Kragh; Møller, Holger Jon.

    In: International Journal of Cancer, Vol. 131, No. 10, 15.11.2012, p. 2320-2331.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Structure of the haptoglobin-haemoglobin complex. / Andersen, Christian Brix Folsted; Torvund-Jensen, Morten; Nielsen, Marianne Jensby; de Oliveira, Cristiano Luis Pinto; Hersleth, Hans-Petter; Andersen, Niels Højmark; Pedersen, Jan Skov; Andersen, Gregers Rom; Moestrup, Søren Kragh.

    In: Nature, Vol. 489, No. 7416, 20.09.2012, p. 456-459.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    CD163-L1 is an endocytic macrophage protein strongly regulated by mediators in the inflammatory response. / Moeller, Jesper B; Nielsen, Marianne J; Reichhardt, Martin P; Schlosser, Anders; Sorensen, Grith L; Nielsen, Ole; Tornøe, Ida; Grønlund, Jørn; Nielsen, Maria E; Jørgensen, Jan S; Jensen, Ole N; Mollenhauer, Jan; Moestrup, Søren K; Holmskov, Uffe.

    In: Journal of Immunology, Vol. 188, No. 5, 2012, p. 2399-409.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Efficient intracellular drug-targeting of macrophages using stealth liposomes directed to the hemoglobin scavenger receptor CD163. / Etzerodt, Anders; Maniecki, Maciej Bogdan; Graversen, Jonas Heilskov; Møller, Holger Jon; Torchilin, Vladimir P; Moestrup, Søren Kragh.

    In: Journal of Controlled Release, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Targeted delivery of dexamethasone to macrophages attenuates the cytokine response without decreasing cortisole levels – a porcine study. / Granfeldt, Asger; Hvas, Christine Lodberg; Graversen, JH; Christensen, PA; Petersen, MD; Anton, G; Svendsen, P; Sølling, Christoffer; Tønnesen, Else Kirstine; Moestrup, Søren Kragh; Møller, HJ.

    2012. Abstract from European Society of Intensive Care Medicine, Lissabon, Portugal.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  14. Published

    Targeting the Hemoglobin Scavenger receptor CD163 in Macrophages Highly Increases the Anti-inflammatory Potency of Dexamethasone. / Graversen, Jonas H; Svendsen, Pia; Dagnæs-Hansen, Frederik; Dal, Jakob; Anton, Gabriele; Etzerodt, Anders; Petersen, Mikkel D; Christensen, Peter A; Møller, Holger J; Moestrup, Søren K.

    In: Molecular Therapy, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Vitamin B12 transport from food to the body's cells--a sophisticated, multistep pathway. / Nielsen, Marianne Jensby; Rasmussen, Mie Rostved; Andersen, Christian Brix Folsted; Nexø, Ebba; Moestrup, Søren Kragh.

    In: Nature Reviews. Gastroenterology & Hepatology, Vol. 9, No. 6, 2012, p. 345-54.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. 2011
  17. Published

    Kupffer cells are activated in cirrhotic portal hypertension and not normalised by TIPS. / Holland-Fischer, Peter; Grønbæk, Henning; Sandahl, Thomas Damgaard; Moestrup, Søren Kragh; Riggio, Oliviero; Ridola, Lorenzo; Aagaard, Niels Kristian; Møller, Holger Jon; Vilstrup, Hendrik.

    In: Gut, Vol. 60, No. 10, 10.2011, p. 1389-93.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Soluble CD163 levels in children with sickle cell disease. / Møller, Holger Jon; Nielsen, Marianne Jensby; Bartram, Jack; Dick, Moira C; Height, Susan E; Moestrup, Soren K; Rees, David C.

    In: British Journal of Haematology, Vol. 153, 20.02.2011, p. 105-10.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Comparative assessment of the recognition of domain-specific CD163 monoclonal antibodies in human monocytes explains wide discrepancy in reported levels of cellular surface CD163 expression. / Maniecki, Maciej Bogdan; Etzerodt, Anders; Moestrup, Søren Kragh; Møller, Holger Jon; Graversen, Jonas Heilskov.

    In: Immunobiology, Vol. 216, 08.02.2011, p. 882-890.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Serum soluble CD163 predicts risk of type 2 diabetes in the general population. / Møller, Holger J; Frikke-Schmidt, Ruth; Moestrup, Søren K; Nordestgaard, Børge; Tybjærg-Hansen, Anne.

    In: Clinical Chemistry (Chicago), Vol. 57, No. 2, 01.02.2011, p. 291-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    The conserved scavenger receptor cysteine-rich superfamily in therapy and diagnosis. / Martínez, Vanesa Gabriela; Moestrup, Søren Kragh; Holmskov, Uffe; Mollenhauer, Jan; Lozano, Francisco.

    In: Pharmacological Reviews, Vol. 63, No. 4, 2011, p. 967-1000.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. 2010
  23. Published

    Structural basis for receptor recognition of vitamin-B(12)-intrinsic factor complexes. / Andersen, Christian Brix Folsted; Madsen, Mette; Storm, Tina; Moestrup, Søren K; Andersen, Gregers Rom.

    In: Nature, Vol. 464, No. 7287, 18.03.2010, p. 445-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Hemoglobin and heme scavenger receptors. / Nielsen, Marianne Jensby; Møller, Holger Jon; Moestrup, Søren Kragh.

    In: Antioxidants & Redox Signaling, Vol. 12, No. 2, 2010, p. 261-273.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  25. Published

    Hemoglobin and heme scavenger receptors. / Nielsen, Marianne Jensby; Møller, Holger Jon; Moestrup, Søren Kragh.

    In: Antioxidants & Redox Signaling, Vol. 12, No. 2, 2010, p. 261-73.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin. / Beedholm-Ebsen, Rasmus; van de Wetering, Koen; Hardlei, Tore; Nexø, Ebba; Borst, Piet; Moestrup, Søren K.

    In: Gekkan Blood, Vol. 115, No. 8, 2010, p. 1632-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Neuronal low-density lipoprotein receptor-related protein 1 binds and endocytoses prion fibrils via receptor cluster 4. / Jen, Angela; Parkyn, Celia J; Mootoosamy, Roy C; Ford, Melanie J; Warley, Alice; Liu, Qiang; Bu, Guojun; Baskakov, Ilia V; Moestrup, Søren; McGuinness, Lindsay; Emptage, Nigel; Morris, Roger J.

    In: Journal of Cell Science, Vol. 123, No. Pt 2, 2010, p. 246-55.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Soluble macrophage-derived CD163: A homogenous ectodomain protein with a dissociable haptoglobin-hemoglobin binding. / Møller, Holger Jon; Maniecki, Maciej Bogdan; Madsen, Mette; Moestrup, Søren Kragh.

    In: Immunobiology, Vol. 215, No. 5, 2010, p. 406-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    Soluble macrophage-derived CD163: a homogenous ectodomain protein with a dissociable haptoglobin-hemoglobin binding. / Møller, Holger Jon; Nielsen, Marianne Jensby; Maniecki, Maciej Bogdan; Madsen, Mette; Moestrup, Søren Kragh.

    In: Immunobiology, Vol. 215, No. 5, 2010, p. 406-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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