Søren Kragh Moestrup

  1. 1998
  2. Published

    The human intrinsic factor-vitamin B12 receptor, cubilin: molecular characterization and chromosomal mapping of the gene to 10p within the autosomal recessive megaloblastic anemia (MGA1) region. / Kozyraki, R; Kristiansen, M; Silahtaroglu, A; Hansen, C; Jacobsen, Christian; Tommerup, N; Verroust, P J; Moestrup, S K.

    In: Blood, Vol. 91, No. 10, 1998, p. 3593-600.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a peripheral megalin-binding membrane protein with homology to developmental proteins. / Moestrup, Søren Kragh; Kozyraki, R.; Kristiansen, M.; Kaysen, J.H.; Holm Rasmussen, H.; Brault, D.; Pontillon, F.; Goda, F.O.; Christensen, Erik Ilsø; Hammond, T.G.; Verroust, P.J.

    In: Journal of Biological Chemistry, Vol. 273, 1998, p. 5235-5242.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    The plasminogen binding site of the C-type lectin tetranectin is located in the carbohydrate recognition domain, and binding is sensitive to both calcium and lysine. / Graversen, Niels Jonas Heilskov; Lorentsen, Rikke; Christian, Christian; Moestrup, Søren Kragh; Sigurskjold, Bent; Thøgersen, Hans Christian; Etzerodt, Michael.

    In: Journal of Biological Chemistry, Vol. 273, No. 44, 1998, p. 29241-29246.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    β2-glycoprotein-I (apolipoprotein H) and β2-glycoprotein-I-phospholipid complex harbor a recognition site for the endocytic receptor megalin. / Moestrup, Søren Kragh; Schousboe, I.; Jacobsen, Christian; Leheste, J.-R.; Christensen, Erik Ilsø; Willnow, T.E.

    In: J. Clin. Invest., Vol. 102, 1998, p. 902-909.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. 1997
  7. Published

    Characterization of an epithelial ≈ 460 kDa protein which mediates endocytosis of Intrinsic Factor Vitamin B12 and binds Receptor-associated Protein. / Birn, Henrik; Verroust, P.; Nexø, Ebba; Hager, Henrik; Jacobsen, Christian; Christensen, Erik Ilsø; Moestrup, Søren Kragh.

    In: Journal of Biological Chemistry, Vol. 272, 1997, p. 26497-26504.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Identification of rat yolk sac targit protein og teratogenic antibodies, gp280, as Intrinsic factor-cobalamin receptor. / Seetharam, B.; Christensen, Erik Ilsø; Moestrup, Søren Kragh; Hammond, T.G.; Verroust, P.J.

    In: J. Clin. Invest., Vol. 99, 1997, p. 2317-2322.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Molecular identification of anovel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography. / Petersen, Claus Munck; Nielsen, Morten Schallburg; Nykjær, Anders; Jacobsen, L.; Tommerup, N.; Rasmussen, H.; Røigaard, H.; Gliemann, Jørgen; Madsen, Peder Søndergaard; Moestrup, Søren Kragh.

    In: Journal of Biological Chemistry, Vol. 272, 1997, p. 3599-3605.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    The intrinsic factor cobalamin receptor expressed by yolk sac and proximal tubule epithelial cells is the target of teratogenic antibodies. / Verroust, P.J.; Christensen, Erik Ilsø; Moestrup, Søren Kragh; Hammond, T.G.; Seetharam, B.

    B12 and B12 binding proteins (Proceedings of the 4th European Symposium on Vitamin B12 and B12-proteins). ed. / B. Kräutler. Vol. Section 7: B12 Medical aspects, Chapter 32 Wileys-Verlag´s Chemie, 1997. p. 491-504.

    Research output: Contribution to book/anthology/report/proceedingArticle in proceedingsResearchpeer-review

  11. 1996
  12. Published

    Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein. / Jacobsen, Linda; Madsen, Peder; Moestrup, Søren K; Lund, Anders Henrik; Tommerup, Niels; Nykjaer, A; Sottrup-Jensen, L; Gliemann, J; Petersen, C M.

    In: Journal of Biological Chemistry, Vol. 271, No. 49, 06.12.1996, p. 31379-31383.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    A flow cytometric competition technique for measuring interaction of LDL with cellular LDL-receptors applied to patients with mutant (Arg3500-->Gln) apolipoprotein B. / Heath, F; Jensen, T G; Hansen, P S; Jensen, L G; Vissinger, H; Moestrup, S K; Pedersen, S; Kølvraa, S; Bolund, L; Faergeman, O.

    In: Zeitschrift fuer Gastroenterologie, Vol. 34 Suppl 3, 06.1996, p. 21-4.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Identification of residues in alpha-macroglobulins important for binding to the alpha2-macroglobulin receptor/Low density lipoprotein receptor-related protein. / Nielsen, Kåre L.; Holtet, Thor L.; Etzerodt, Michael; Moestrup, Søren Kragh; Gliemann, Jørgen; Sottrup-Jensen, Lars; Thøgersen, Hans Christian.

    In: Journal of Biological Chemistry, Vol. 271, No. 22, 1996, p. 12909-12912.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Immunohistochemical localization of urokinase‑type plasminogen activator, type‑1 plasminogen activator inhibitor, urokinase receptor and alpha(2)‑macroglobulin receptor in human breast carcinomas. / Christensen, Lise; Wiborg Simonsen, Anna Carina; Heegaard, Christian Wurtz; Moestrup, Søren Kragh; Andersen, Johan A.; Andreasen, Peter.

    In: International Journal of Cancer, Vol. 66, 1996, p. 441-452.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Megalin-mediated endocytosis of vitamin B12-transcobalamin complexes suggests an important role of the receptor in vitamin B12 homeostasis. / Moestrup, Søren Kragh; Birn, Henrik; Fischer, P.B.; Petersen, Claus Munck; Verroust, P.J.; Sim, R.B.; Christensen, Erik Ilsø; Nexø, Ebba.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, 1996, p. 8612-8617.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Megalin/gp330 mediates uptake of albumin in renal proximal tubule. / Cui, S.; Verroust, P.; Moestrup, Søren Kragh; Christensen, Erik Ilsø.

    In: Am. J. Physiol. (Renal Fluid Electrolyte Physiol.), Vol. 271, 1996, p. F900-F907.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    The receptor-associated protein (RAP) binds calmodulin and is phosphorylated by calmodulin-dependent kinase II. / Petersen, Claus Munck; Ellgaard, Lars; Nykjær, Anders; Vilhardt, F.; Vorum, Henrik; Thøgersen, Hans Christian; Nielsen, Morten Schallburg; Jacobsen, Christian; Moestrup, Søren Kragh; Gliemann, Jørgen.

    In: E M B O Journal, Vol. 15, No. 16, 1996, p. 4165-4173.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. 1995
  20. Published

    Analysis of the binding of pro-urokinase-plasminogen activator inhibitor-1 complex to the low density lipoprotein receptor-related protein using a Fab fragment selected from a phage-displayed Fab library. / Horn, I. R.; Moestrup, Søren Kragh; van den Berg, B. M. M.; Pannekoek, H.; Nielsen, Morten Schallburg; van Zonneveld, A. J.

    In: Journal of Biological Chemistry, Vol. 270, 1995, p. 11770-11775.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Evidence that epithelial glycoprotein 330/Megalin mediates uptake of polybasic drugs. / Moestrup, Søren Kragh; Cui, S.; Vorum, Henrik; Bregengård, C.; Bjørn, S.E.; Norris, K.; Gliemann, Jørgen; Christensen, Erik Ilsø.

    In: J. Clin. Invest., Vol. 96, 1995, p. 1404-1413.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Nested sets of protein fragments and their use in epitope mapping: characterization of the epitope for the S4D5 monoclonal antibody binding to Receptor Associated Protein. / Ellgaard, Lars; Holtet, Thor L.; Moestrup, Søren Kragh; Etzerodt, Michael; Thøgersen, Hans Christian.

    In: J. Immunol. Methods, Vol. 180, No. 1, 1995, p. 53-61.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Segmental distribution of the endocytosis receptor gp330 in renal proximal tubules. / Christensen, Erik Ilsø; Nielsen, Søren; Moestrup, Søren Kragh; Borre, C.; Maunsbach, Arvid B.; de Heer, E.; Ronco, P.; Hammond, T.G.; Verroust, P.

    In: Eur. J. Cell Biol., Vol. 66, 1995, p. 349-364.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. 1994
  25. Published

    Binding and endocytosis of protein madiated by gp330. / Moestrup, Søren Kragh; Christensen, Erik Ilsø; Nielsen, Søren; Bjørn, S.E.; Jørgensen, K.E.; Røigaard, H.; Gliemann, Jørgen.

    In: Ann. N. Y. Acad. Sci., Vol. 737, 1994, p. 127-137.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  26. Published

    Receptor-binding domain of human alpha(2)-Macroglobulin. Expression, folding and biochemical characterization of a high-affinity recombinant derivative. / Holtet, Thor L.; Nielsen, Kåre L.; Etzerodt, Michael; Moestrup, Søren Kragh; Gliemann, Jørgen; Sottrup-Jensen, Lars; Thøgersen, Hans Christian.

    In: F E B S Letters, Vol. 344, No. 2-3, 1994, p. 242-246.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Receptor-mediated endocytosis of plasminogen activators and activator/inhibitor complexes. / Andreasen, P A; Sottrup-Jensen, L; Kjøller, L; Nykjaer, A; Moestrup, S K; Petersen, C M; Gliemann, J.

    In: F E B S Letters, Vol. 338, No. 3, 1994, p. 239-45.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Recombinant alpha(2)M receptor binding domain binds to the alpha(2)M receptor with high affinity. / Holtet, Thor L.; Nielsen, Kåre L.; Etzerodt, Michael; Moestrup, Søren Kragh; Gliemann, Jørgen; Sottrup-Jensen, Lars; Thøgersen, Hans Christian.

    In: Ann. N. Y. Acad. Sci., Vol. 737, 1994, p. 480-482.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  29. Published

    The multiligand α2-macroglobulin receptor/low density lipoprotein receptor-related protein. / Gliemann, Jørgen; Nykjær, Anders; Petersen, Claus Munck; Jørgensen, K.E.; Andreasen, Peter; Christensen, Erik Ilsø; Moestrup, Søren Kragh.

    In: New York Academy of Sciences. Annals, Vol. 737, 1994, p. 20-38.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  30. Published

    The α2-macroglobulin receptor/low density lipoprotein receptor-related protein. Binding and endocytosis of fluid-phase and membrane-associated ligands. / Gliemann, Jørgen; Nykjær, Anders; Petersen, Claus Munck; Jørgensen, K. E.; Nielsen, Morten Schallburg; Andreasen, Peter; Christensen, Erik Ilsø; Lookene, A.; Olivecrona, G.; Moestrup, Søren Kragh.

    In: Ann. N. Y. Acad. Sci., Vol. 737, 1994, p. 20-38.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. 1993
  32. Published

    Epithelial glycoprotein-330 mediates endocytosis of plasminogen activator-plasminogen activator inhibitor type-1 complexes. / Moestrup, S K; Nielsen, Susanne; Andreasen, P; Jørgensen, K E; Nykjaer, A; Røigaard, H; Gliemann, J; Christensen, E I.

    In: Journal of Biological Chemistry, Vol. 268, No. 22, 05.08.1993, p. 16564-16570.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Alpha 2-macroglobulin-proteinase complexes, plasminogen activator inhibitor type-1-plasminogen activator complexes, and receptor-associated protein bind to a region of the alpha(2)-Macroglobulin receptor containing a cluster of eight complement-type repeats. / Moestrup, Søren Kragh; Holtet, Thor L.; Etzerodt, Michael; Thøgersen, Hans Christian; Nykjær, Anders; Andreasen, Peter; Rasmussen, H.H.; Sottrup-Jensen, Lars; Gliemann, Jørgen.

    In: Journal of Biological Chemistry, Vol. 268, No. 18, 1993, p. 13691-13696.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds lipoprotein lipase and beta-migrating very low density lipoprotein associated with the lipase. / Nykjaer, A; Bengtsson-Olivecrona, G; Lookene, A; Moestrup, S K; Petersen, C M; Weber, W; Beisiegel, U; Gliemann, J.

    In: Journal of Biological Chemistry, Vol. 268, No. 20, 1993, p. 15048-55.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. 1992
  36. Published

    Purified alpha(2)-Macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha(2)-Macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes. / Nykjær, Anders; Petersen, Claus Munck; Møller, B.; Jensen, Poul Henning; Moestrup, Søren Kragh; Holtet, Thor L.; Etzerodt, Michael; Thøgersen, Hans Christian; Munch, Mette; Andreasen, Peter; Gliemann, Jørgen.

    In: Journal of Biological Chemistry, Vol. 267, No. 21, 1992, p. 14543-14546.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Renal tubule gp330 is a calcium-binding receptor for endocytic uptake of protein. / Christensen, Erik Ilsø; Gliemann, Jørgen; Moestrup, Søren Kragh.

    In: J. Histochem. Cytochem., Vol. 40, 1992, p. 1481-1490.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. 1990
  39. Published

    Evidence that the newly cloned low-density-lipoprotein receptor related protein (LRP) is the alpha 2-macroglobulin receptor. / Kristensen, Torsten; Moestrup, Søren Kragh; Gliemann, Jørgen; Bendtsen, Lone; Sand, Ole; Sottrup-Jensen, Lars.

    In: FEBS Letters, Vol. 276, No. 1-2, 10.12.1990, p. 151-155.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    Cellular targets and receptors for interleukin-6. II. Characterization of IL-6 binding and receptors in peripheral blood cells and macrophages. / Petersen, Claus Munck; Davidsen, O; Moestrup, S K; Sonne, O; Nykjaer, A; Møller, B K.

    In: European Journal of Clinical Investigation, Vol. 20, No. 4, 1990, p. 377-84.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  41. Published

    Immunocytochemical identification of the human alpha 2-macroglobulin receptor in monocytes and fibroblasts: monoclonal antibodies define the receptor as a monocyte differentiation antigen. / Moestrup, S K; Kaltoft, Keld; Petersen, Claus Munck; Pedersen, S; Gliemann, J; Christensen, Erik Ilsø.

    In: Experimental Cell Research, Vol. 190, No. 2, 1990, p. 195-203.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    Interactions between cytokines and alpha 2 macroglobulin. / Petersen, C M; Moestrup, S K.

    In: Trends in Immunology, Vol. 11, No. 12, 1990, p. 430-1.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. 1989
  44. Published

    Immunosuppressive properties of electrophoretically "slow" and "fast" form alpha 2-macroglobulin. Effects on cell-mediated cytotoxicity and (allo-) antigen-induced T cell proliferation. / Petersen, C M; Ejlersen, E; Moestrup, S K; Jensen, Poul Henning; Sand, O; Sottrup-Jensen, L.

    In: Journal of Immunology, Vol. 142, No. 2, 15.01.1989, p. 629-635.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. 1988
  46. Published

    Receptors for a2-Macroglobulin- and pregnancy zone protein-proteinase complexes in the human placental syncytiotrophoblast. / Jensen, Poul Henning; Moestrup, S K; Sottrup-Jensen, Lars; Petersen, Claus Munch; Gliemann, Jørgen.

    In: Placenta, Vol. 9, No. 5, 09.1988, p. 463-477.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    Human hepatocytes exhibit receptors for alpha 2-macroglobulin and pregnancy zone protein-proteinase complexes. / Petersen, C M; Christiansen, B S; Jensen, Poul Henning; Moestrup, S K; Gliemann, J; Sottrup-Jensen, L; Ingerslev, J.

    In: European Journal of Clinical Investigation, Vol. 18, No. 2, 1988, p. 184-90.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  48. 1987
  49. Published

    Binding and receptor-mediated endocytosis of pregnancy zone protein-proteinase complex in rat macrophages. / Moestrup, S K; Christensen, Erik Ilsø; Sottrup-Jensen, L; Gliemann, J.

    In: BBA General Subjects, Vol. 930, No. 3, 1987, p. 297-303.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. 1986
  51. Published

    Evidence for binding of human pregnancy zone protein-proteinase complex to a2-Macroglobulin receptors. / Gliemann, Jørgen; Moestrup, Søren Kragh; Jensen, Poul Henning; Sottrup-Jensen, L; Andersen, Hanne Busk; Petersen, Claus Munck; Sonne, Ole; Madsen, Peder.

    In: BBA General Subjects, Vol. 883, No. 3, 01.10.1986, p. 400-406.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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