Søren Kragh Moestrup

  1. 2007
  2. Published

    The macrophage CD163 surface glycoprotein is an erythroblast adhesion receptor. / Fabriek, B.O.; Polfliet, M.M.J.; de Lavalette, C.R.; Vloet, R.P.M.; van der Schors, R.C.; Legtenberg, A.J.M.; Weaver, L.K.; Moestrup, Søren Kragh; Dijkstra, C.D.; van Berg, T.

    In: Blood, Vol. 109, 2007, p. 5223-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

      ‘Shillings test' on cultured cells reveals cellular export of free vitamin B12. / Beedholm, Rasmus; Fedosov, Sergey; Nexø, Ebba; Moestrup, Søren Kragh.

    2007. Poster session presented at Vitamin B12 & Corphins, Gordon Research Conferences, United States.

    Research output: Contribution to conferencePosterResearch

  4. 2006
  5. Published

    Application of a fluorescent Cbl-analoque for analysis of the binding kinetics. A study employing recombinant human transcobalamin and intrinsic factor. / Fedosov, Sergey; Grissom, Charles B.; Fedosova, Natalya U.; Moestrup, Søren Kragh; Nexø, Ebba; Petersen, Torben Ellebæk.

    In: F E B S Journal, Vol. 273, 2006, p. 4742-4753.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    CD163 positive subsets of blood dendritic cells: The scavenging macrophage receptors CD163 and CD91 are coexpressed on human dendritic cells and monocytes. / Maniecki, Maciej Bogdan; Møller, Holger Jon; Moestrup, Søren Kragh; Møller, Bjarne.

    In: Immunobiology, Vol. 211, 2006, p. 407-417.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Changes in Fat Mass Correlate With Changes in Soluble sCD163, a Marker of Mature Macrophages, in Patients With CKD. / Axelsson, Jonas; Møller, Holger Jon; Witasp, Anna; Qureshi, Abdul Rashid; Carrero, Juan Jesus; Heimbürger, Olof; Bárány, Peter; Alvestand, Anders; Lindholm, Bengt; Moestrup, Søren Kragh; Stenvinkel, Peter.

    In: Am J of Kidney Diseases, Vol. 48, No. 6, 2006, p. 916-925.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Differential expression of monocyte CD163 in single - and dual - asthmatic responders during allergen-induced bronchoconstriction. / Kowal, K.; Møller, Holger Jon; DuBuske, L.M.; Moestrup, Søren Kragh; Bodzenta-Lukaszyk, A.

    In: Clinical and Experimental Allergy, Vol. 36, 2006, p. 1584-1591.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Dyslipoproteinaemi--en riskofaktor for både arteriel og venøs trombose? / Nielsen, Lars B; Moestrup, Søren Kragh.

    In: Ugeskrift for Laeger, Vol. 168, No. 8, 2006, p. 802-3.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation. / Theilgaard-Mönch, Kim; C. Jacobsen, Lars; Nielsen, Marianne Jensby; Rasmussen, Thomas; Udby, Lene; Gharib, Maged; D. Arkwright, Peter; F. Gombart, Adrian; Calafat, Jero; Moestrup, Søren Kragh; T. Porse, Bo; Borregaard, Niels.

    In: Blood, Vol. 108, No. 1, 2006, p. 353-61.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Haptoglobin-related protein is a high-affinity hemoglobin-binding plasma protein. / Nielsen, Marianne Jensby; Petersen, Steen Vang; Jacobsen, Christian; Oxvig, Claus; Rees, David; Møller, Holger Jon; Moestrup, Søren Kragh.

    In: Blood, Vol. 108, No. 8, 2006, p. 2846-2849.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    High-density lipoprotein and innate immunity. / Nielsen, Marianne Jensby; Nielsen, Lars Bo; Moestrup, Søren Kragh.

    In: Future Lipidology, Vol. 1, No. 6, 2006, p. 729-734.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  13. Published

    Lipid metabolism: An apolipoprotein-derived weapon combating trypanosoma infection. / Nielsen, Lars Bo; Nielsen, Marianne Jensby; Moestrup, Søren Kragh.

    In: Current Opinion in Lipidology, Vol. 17, 2006, p. 699-701.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperLetter

  14. Published

    Lipids metabolism: lipids and lipoproteins - effect on blood clotting and risk of venous thrombosis. / Nielsen, Lars B; Moestrup, Søren K.

    In: Current Opinion in Lipidology, Vol. 17, No. 1, 2006, p. 89-91.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Megalin Is a Receptor for Apolipoprotein M, and Kidney-Specific Megalin-deficiency Confers Urinary Excretion of Apolipoprotein M. / Faber, K.; Hvidberg, Vibeke; Moestrup, Søren Kragh; Dahlbäck, B.; Nielsen, L. B.

    In: Mol. Endocrinol., Vol. 20, No. 1, 2006, p. 212-218.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    New insights into carrier binding and epithelial uptake of the erythropoietic nutrients cobalamin and folate. / Moestrup, Søren K.

    In: Current Opinion in Hematology, Vol. 13, No. 3, 2006, p. 119-23.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Soluble haemoglobin scavenger receptor (sCD163) in patients with suspected community-acquired infections. / Gaïni, Shahin; Koldkjær, Ole D.; Pedersen, Svend S.; Pedersen, Court; Moestrup, Søren Kragh; Møller, Holger Jon.

    In: Acta Pathologica Microbiologica et Immunologica Scandinavica, Vol. 114, 2006, p. 103-111.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors. / Van den Steen, Philippe E.; Van Aelst, Ilse; Hvidberg, Vibeke; Piccard, Helene; Fiten, Pierre; Jacobsen, Christian; Moestrup, Søren Kragh; Fry, Simon; Royle, Louise; Wormald, Mark R.; Wallis, Russell; Rudd, Pauline M.; Dwek, Raymond A.; Opdenakker, Ghislain.

    In: JBC, Vol. 281, 2006, p. 18626-18637.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    The macrophage scavenger receptor CD163: endocytic properties of cytoplasmic tail variants. / Nielsen, Marianne Jensby; Madsen, Mette; Møller, Holger Jon; Moestrup, Søren Kragh.

    In: J. Leukoc. Biol., Vol. 79, 2006, p. 837-845.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    The monocytic lineage soluble CD163 is a plasma marker of coronary atherosclerosis. / Aristoteli, L.P.; Bailey, B.; Møller, Holger Jon; Moestrup, Søren Kragh; Kritharides, L.

    In: Atherosclerosis, No. 184, 2006, p. 342-347.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Wilms' tumor 1 mutation accumulated during therapy in acute myeloid leukemia : Biological and clinical implications. / Nyvold, C G; Stentoft, J; Braendstrup, K; Melsvik, D; Moestrup, S K; Juhl-Christensen, C; Hasle, H; Hokland, P.

    In: Leukemia, Vol. 20, No. 11, 2006, p. 2051-4.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. 2005
  23. Published

    Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo. / He, Q.; Madsen, Mette; Kilkenney, A.; Gregory, B.; Christensen, Erik Ilsø; Vorum, Henrik; Højrup, P.; Schäffer, A. A.; Tanner, S. M.; de la Chapelle, A.; Giger, U.; Moestrup, Søren Kragh; Fyfe, J. C.

    In: Blood, Vol. 106, 2005, p. 1447-1453.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Composite organization of the cobalamin binding and cubilin recognition sites of intrinsic factor. / Fedosov, Sergey; Fedosova, Natalya U.; Berglund, L.; Moestrup, Søren Kragh; Nexø, Ebba; Petersen, Torben Ellebæk.

    In: Biochemistry, Vol. 44, 2005, p. 3604-3614.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Contribution of cubilin and amnionless to the processing and membrane targeting of the cubilin-amnionless complex. / Coudroy, G.; Kozyraki, R.; Madsen, Mette; Trugnan, G.; Moestrup, Søren Kragh; Verroust, P. J.; Maurice, M.

    In: Journal of the American Society of Nephrology, Vol. 16, 2005, p. 2330-2337.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Identification of the receptor scavenging hemopexin-heme complexes. / Hvidberg, Vibeke; Maniecki, M. B.; Jacobsen, Christian; Hojrup, P.; Moller, H. J.; Moestrup, Søren Kragh.

    In: Blood, Vol. 106, No. 7, 2005, p. 2572-2579.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Megalin binds and mediates cellular internalization of folate binding protein. / Birn, H.; Zhai, X.; Holm, J.; Hansen, S. I.; Jacobsen, Christian; Christensen, Erik Ilsø; Moestrup, Søren Kragh.

    In: F E B S Journal, Vol. 272, 2005, p. 4423-4430.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Plasma haptoglobin modulates iron loading. / Fagoonee, S.; Gburek, J.; Hisch, E.; Marro, S.; Moestrup, Søren Kragh; Laurberg, J. M.; Christensen, Erik Ilsø; Silengo, L.; Altruda, F.; Tolosano, E.

    In: American Journal of Pathology, Vol. 166, 2005, p. 973-983.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    Predictive value of soluble haemoglobin scavenger receptor CD163 serum levels for survival in verified tuberculosis patients. / Knudsen, T.B.; Gustafson, P.; Kronborg, G.; Christiansen, T.B.; Moestrup, Søren Kragh; Nielsen, J.O.; Gomed, V.; Aaby, P.; Lisse, I.; Møller, Holger Jon; Eugen-Olsen, J.

    In: Clin Mikrobiol Infect, Vol. 11, No. 9, 2005, p. 730-735.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Preterm delivery predicted by soluble CD163 and CRP in women with symptoms of preterm delivery. / Vogel, Ida; Grove, Jakob; Thorsen, Poul; Moestrup, Søren K; Uldbjerg, Niels; Møller, Holger Jon.

    In: B J O G, Vol. 112, No. 6, 2005, p. 737-42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    Preterm delivery predicted by soluble CD163 and CRP in women with symptoms of preterm delivery. / Vogel, I.; Grove, J.; Thorsen, P.; Moestrup, Søren Kragh; Uldbjerg, N.; Møller, H. J.

    In: Brit. J. Obs. Gyn., Vol. 112, 2005, p. 737-742.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Soluble CD163 and interleukin 6 are increased in aqueous humor from patients with endothelial rejection of corneal grafts. / Funding, M.; Vorum, Henrik; Nexø, Ebba; Moestrup, Søren Kragh; Ehlers, N.; Møller, H. J.

    In: Acta Ophthalmologica, Vol. 83, 2005, p. 234-239.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Soluble CD163 and interleukin-6 are increased in aqueous humour from patients with endothelial rejection of corneal grafts. / Funding, Mikkel; Vorum, Henrik; Nexø, Ebba; Moestrup, Søren Kragh; Ehlers, Niels; Møller, Holger Jon.

    In: Acta Ophthalmologica Scandinavia, No. 83, 2005, p. 234-239.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Soluble CD163 is a plasma marker of coronary atherosclerosis. / Aristoteli, L. P.; Møller, H. J.; Moestrup, Søren Kragh; Kritharides, L.

    In: Atherosclerosis, 2005.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Soluble hemoglobin - haptoglobin scavenger receptor CD163 as a lineage-specific marker in the reactive hemophagocytic syndrome. / Schaer, D.J.; Schleiffenbaum, B.; Kurrer, M.; Imhof, A.; Bächli, E.; Fehr, J.; Møller, Holger Jon; Moestrup, Søren Kragh; Schaffner, A.

    In: Eur. J. Haematol., No. 74, 2005, p. 6-10.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Soluble hemoglobin scavenger receptor CD163 predicts survival in Tuberculosis. / Knudsen, T. B.; Gustafson, P.; Kronborg, G.; Kristiansen, T. B.; Moestrup, Søren Kragh; Nielsen, J. O.; Gomes, V.; Aaby, P.; Lisse, I.; Møller, H. J.; Eugen-Olsen, J.

    In: Clin. Microbiol. Infect., Vol. 11, 2005, p. 730-735.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Soluble hemoglobin-haptoglobin scavenger receptor CD163 as a lineage specific marker of macrophage activation in the hemophagocytic syndrome. / Schaer, D. J.; Schleiffenbaum, B.; Kurrer, M.; Imhof, A.; Bächli, E.; Fehr, J.; Møller, H. J.; Moestrup, Søren Kragh; Schaffner, A.

    In: Eur. J. Haematol., Vol. 74, 2005, p. 6-10.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin (NGAL) with high affinity and mediates its cellular uptake. / Hvidberg, Vibeke; Jacobsen, Christian; Strong, R. K.; Cowland, J. B.; Moestrup, Søren Kragh; Borregaard, N.

    In: F E B S Letters, Vol. 579, 2005, p. 773-777.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    The iron hormone hepcidin: A future diagnostic marker and therapeutic target in the treatment of anemia and hemochromatosis? / Moestrup, Søren Kragh; Møller, Holger Jon.

    In: Ugeskrift for Laeger, Vol. 167, No. 41, 2005, p. 3894-3895.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  40. Published

    The role of the kidney in lipid metabolism. / Moestrup, Søren Kragh; Nielsen, L. B.

    In: Curr. Opin. Lipid., Vol. 16, 2005, p. 301-306.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  41. 2004
  42. Published

    Assembly of the intrinsic factor domains and oligomerization of the protein in the presence of cobalamin. / Fedosov, Sergey; Fedosova, Natalya U.; Berglund, L.; Moestrup, Søren Kragh; Nexø, Ebba; Petersen, Torben Ellebæk.

    In: Biochemistry, Vol. 43, 2004, p. 15095-15102.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. Published

    CD163: A regulated haemoglobin scavenger receptor with a role in the anti-inflammatory response. / Moestrup, Søren Kragh; Møller, H.J.

    In: Annals of Medicine, Vol. 36, 2004, p. 347-353.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  44. Published

    Cobalamin induced dimerization of intrinsic factor. I. Structural aspects of the ligand binding and self-assembly. / Fedosov, S.N.; Fedosova, N.U.; Berglund, L.; Moestrup, S.K.; Nexø, E.; Petersen, T.E.

    In: Biochemistry, Vol. 43, 2004, p. 15095-15102.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  45. Published

    Cubilin and Amnionless are partners in a novel receptor complex for endocytosis. / Fyfe, J.C.; Madsen, Mette; Højrup, P.; Christensen, Erik Ilsø; Tanner, S.M.; de la Chapelle, A.; He, Q.; Moestrup, Søren Kragh.

    In: Blood, Vol. 103, 2004, p. 1573-1579.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  46. Published

    Local production of soluble CD163 impairs lymphocyte activation in spondyloarthropathy synovitis. / Baeten, D.; Møller, H.J.; Delanghe, J.; Veys, E.M.; Moestrup, Søren Kragh; De Keyser, P.

    In: Arthritis Rheum, Vol. 5, 2004, p. 1611-1623.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  47. Published

    Molecular characterization of the haptoglobin-hemoglobin receptor CD163. Ligand binding properties of the scavenger receptor cysteine-rich domain region. / Madsen, Mette; Møller, M.J.; Jacobsen, Christian; Graversen, J.H.; van den Berg, T.; Moestrup, Søren Kragh.

    In: Journal of Biological Chemistry, Vol. 279, 2004, p. 51561-51567.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  48. Published

    Molecular characterization of the haptoglobin-hemoglobin receptor CD163: ligand binding properties of the scavenger receptor cysteine-rich domain region. / Madsen, Mette; J. Møller, Holger; Nielsen, Marianne Jensby; Christian, Christian; Heilskov Graversen, Jonas; van den Berg, Timo; Moestrup, Søren Kragh.

    In: Journal of Biological Chemistry, Vol. 279, No. 49, 2004, p. 51561-51567.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  49. Published

    Soluble hemoglobin scavenger receptor: A macrophage-specific marker in Gaucher disease. / Møller, H.J.; de Fost, M.; Aerts, H.; Hollak, C.; Moestrup, Søren Kragh.

    In: Eur. J. Haematol., Vol. 72, 2004, p. 135-139.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  50. Published

    Using Biacore technology to characterize receptors for macromolecular complexes. / Jacobsen, Christian; Moestrup, Søren Kragh.

    In: Biacore J, Vol. 4, 2004, p. 13-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. 2003
  52. Published

    Biological variation of soluble CD163. / Møller, Holger Jon; Petersen, P.H.; Rejnmark, Lars; Moestrup, Søren Kragh.

    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 63, No. 1, 2003, p. 15-21.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Biological variation of soluble CD163. / Møller, H.J.; Petersen, P.H.; Rejnmark, L.; Moestrup, Søren Kragh.

    In: Scandinavian Journal of Clinical & Laboratory Investigation, No. 63, 2003, p. 15-22.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  54. Published

    Generation of a haptoglobin-hemoglobin complex-specific Fab antibody blocking the binding of the complex to CD163. / Horn, I.R.; Nielsen, Marianne Jensby; Madsen, Mette; Jacobsen, Christian; Graversen, J.H.; Moestrup, Søren Kragh.

    In: Eur. J. Haematol., No. 71, 2003, p. 289-293.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  55. Published

    Human intrinsic factor expressed in the plant Arabidopsis thaliana. / Fedosov, Sergey; Laursen, N.B.; Moestrup, Søren Kragh; Nexø, E.; Petersen, Torben Ellebæk; Jensen, Erik Østergaard; Berglund, L.

    In: F E B S Journal, No. 270, 2003, p. 3362-3367.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  56. Published

    Human intrinsic factor expressed in the plant Arabidopsis thaliana. / Fedosov, Serguei; Laursen, N.B.; Nexø, E.; Moestrup, Søren Kragh; Petersen, T.E.; Jensen, E.Ø.; Berglund, L.

    In: F E B S Journal, 2003, p. 166-42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  57. Published

    Megalin, cubilin and immunoglobulin light chains. Receptor mediated uptake of light chains in kidney proximal tubules. / Birn, Henrik; Leboulleux, M.; Moestrup, Søren Kragh; Ronco, P.M.; Aucouturier, P.; Christensen, Erik Ilsø.

    Monoclonal gammopathies and the kidney. ed. / G. Touchard; P. Aucouturier; O. Hermine; P.M. Ronco. The Netherlands : Kluwer Academic Publishers, 2003. p. 37-48.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearch

  58. Published

    Receptorernes dirigering af makromolekyler. / Moestrup, Søren Kragh.

    In: Lundbeckfondens Årsskrift 2002, 2003, p. 22-24.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  59. Published

    Renal uptake of myoglobin is mediated by the endocytic receptors megalin and cubilin. / Gburek, J.; Birn, H.; Verroust, P.J.; Goj, B.; Jacobsen, Christian; Moestrup, Søren Kragh; Willnow, T.E.; Christensen, Erik Ilsø.

    In: American Journal of Physiology: Renal Physiology, No. 285, 2003, p. 451-458.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  60. Published

    Soluble CD163: a marker molecule for monocyte/macrophage activity in diseases. / Møller, Holger Jon; Aerts, H.; Grønbæk, Henning; Peterslund, Niels Anker; Petersen, P.H.; Hornung, N.; Rejnmark, Lars; Jabbarpour, E.; Moestrup, Søren Kragh.

    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 62 Suppl 237, 2003, p. 29-34.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  61. 2002
  62. Published

    CD163: a signal receptor scavenging haptoglobin-hemoglobin complexes from plasma. / Graversen, J. H.; Madsen, Mette; Moestrup, Søren Kragh.

    In: Int. J. Biochem. Cell Biol., Vol. 34, 2002, p. 309-314.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  63. Published

    Characterization of an enzyme linked immunosorbent assay for soluble CD163. / Møller, H.J.; Hald, K.; Moestrup, Søren Kragh.

    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 62, 2002, p. 293-299.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  64. Published

    Characterization of an enzyme linked immunosorbent assay for soluble CD163. / Møller, H.J.; Hald, K.; Moestrup, Søren Kragh.

    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 62, 2002, p. 293-300.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  65. Published

    Identification of the hemoglobin scavenger receptor/CD163 as a natural soluble protein in plasma. / Møller, H.J.; Peterslund, N.A.; Graversen, J.H.; Moestrup, Søren Kragh.

    In: Blood, Vol. 99, 2002, p. 378-380.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  66. Published

    Identification of the hemoglobin scavenger receptor/CD163 as a natural soluble protein in plasma. / Møller, H.J.; Peterslund, N.A.; Graversen, J.H.; Moestrup, Søren Kragh.

    In: Blood, Vol. 99, 2002, p. 378-380.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  67. Published

    Identification of the hemoglobin scavenger receptor/CD163 as a natural soluble protein in plasma. / Møller, H.J.; Peterslund, N.A.; Graversen, J.H.; Moestrup, Søren Kragh.

    In: Blood, No. 99, 2002, p. 378-380.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  68. Published

    Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin. / Gburek, J.; Verroust, P.J.; Willnow, T.E.; Fyfe, J.C.; Nowachi, W.; Jacobsen, Christian; Moestrup, Søren Kragh; Christensen, Erik Ilsø.

    In: Journal of the American Society of Nephrology, Vol. 13, 2002, p. 423-430.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  69. Published

    Megalin binds and mediates cellular uptake of the folate binding protein. / Birn, H.; Zhai, X.Y.; Holm, J.; Hansen, S.I.; Jacobsen, C.; Moestrup, S.K.; Christensen, E.I.

    In: Journal of the American Society of Nephrology, Vol. 13, 2002, p. 486-486.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  70. Published

    Megalin is essential for renal proximal tubule reabsorption and accumulation of transcobalamin-B12. / Birn, H.; Willnow, T.; Nielsen, R.; Norden, A.G.; Moestrup, Søren Kragh; Nexø, E.; Christensen, Erik Ilsø.

    In: American Journal of Physics, Vol. 282, 2002, p. 408-416.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  71. Published

    Renal uptake of myoglobin is mediated by the endocytic receptors megalin and cubilin. / Gburek, J.; Birn, H.; Verroust, P.J.; Goj, B.; Jacobsen, C.; Moestrup, S.K.; Christensen, E.I.

    In: Journal of the American Society of Nephrology, Vol. 13, 2002, p. 486-487.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  72. Published

    Soluble CD163: A marker molecule for monocyte/macrophage activity in disease. / Møller, H.J.; Aerts, H.; Grønbæk, H.; Peterslund, N.A.; Hyltoft Petersen, P.; Hornung, N.; Rejnmark, L.; Jabbarpour, E.; Moestrup, Søren Kragh.

    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 62, 2002, p. 29-33.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  73. Published

    Specificity determinants in the interaction of apolipoprotein(a) kringles with tetranectin and LDL. / Caterer, N.R.; Graversen, J.H.; Jacobsen, Christian; Moestrup, Søren Kragh; Sigurskjold, B.W.; Etzerodt, Michael; Thøgersen, Hans Christian.

    In: Biological Chemistry, Vol. 383, No. 11, 2002, p. 1743-1750.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  74. Published

    Urinary megalin deficiency implicates abnormal tubular endocytic function in Fanconi syndrome. / Norden, A.G.; Lapsley, M.; Igarashi, T.; Kelleher, C.L.; Lee, P.; Matsuyama, T.; Scheinman, S.J.; Shiraga, H.; Sundin, D.P.; Thakker, R.V.; Unwin, R.J.; Verroust, P.; Moestrup, Søren Kragh.

    In: Journal of the American Society of Nephrology, Vol. 13, 2002, p. 125-133.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  75. 2001
  76. Published

    A two-receptor pathway for catabolism of Clara cell secretory protein in the kidney. / Burmeister, R.; Boe, I.M.; Nykjær, Anders; Jacobsen, Christian; Moestrup, Søren Kragh; Verroust, P.; Christensen, Erik Ilsø; Lund, J.; Willnow, T.E.

    In: Journal of Biological Chemistry, Vol. 276, 2001, p. 13295-13301.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  77. Published

    Analysis of a two-domain binding site for the urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex in low density lipoprotein receptor-related protein. / Andersen, O.M.; Petersen, H.H.; Jacobsen, Christian; Moestrup, Søren Kragh; Etzerodt, M.; Andreasen, Peter; Thøgersen, H.C.

    In: Biochem. J., Vol. 357, 2001, p. 289-296.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  78. Published

    Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3). / Nykjær, Anders; Fyfe, J.C.; Kozyraki, R.; Leheste, J.R.; Jacobsen, Christian; Nielsen, Morten Schallburg; Verroust, P.J.; Aminoff, M.; de la Chapelle, A.; Moestrup, Søren Kragh; Ray, R.; Gliemann, Jørgen; Willnow, T.E.; Christensen, Erik Ilsø.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, 2001, p. 13895-13900.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  79. Published

    Cubilin- and megalin-mediated endocytosis of protein-bound vitamins, hormones and lipids in polarized cells. / Moestrup, Søren Kragh; Verroust, P.J.

    In: Ann. Rev. Nutrition, Vol. 21, 2001, p. 407-428.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  80. Published

    Dominant thermodynamic role of the third independent receptor binding site in the receptor-associated protein RAP. / Andersen, O.M.; Schwarz, F.P.; Eisenstein, E.; Jacobsen, Christian; Moestrup, Søren Kragh; Etzerodt, Michael; Thøgersen, Hans Christian.

    In: Biochemistry, Vol. 40, 2001, p. 15408-15417.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  81. Published

    Evidence for and accessory activity required for cubilin expression - not for an alternative intrinsic factor-cobalamin receptor. / Moestrup, Søren Kragh; Kristiansen, M.

    In: Blood, Vol. 97, 2001, p. 3317-3318.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  82. Published

    Haptoglobin and CD163: captor and receptor gating hemoglobin to macrophage lysosomes. / Madsen, Mette; Graversen, J. H.; Moestrup, Søren Kragh.

    In: Redox Report (Online), Vol. 6, 2001, p. 386-388.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  83. Published

    Identification of the haemoglobin scavenger receptor. / Madsen, Mette; Graversen, J. H.; Jacobsen, Christian; Sonne, Ole; Hoffmann, H.-J.; Law, S. K. A.; Moestrup, Søren Kragh.

    In: Nature, Vol. 409, 2001, p. 198-201.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  84. Published

    Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia. / Kozyraki, R.; Fyfe, J.; Verroust, P.J.; Jacobsen, Christian; Dautry-Varsat, A.; Gburek, J.; Willnow, T.E.; Christensen, Erik Ilsø; Moestrup, Søren Kragh.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, 2001, p. 12491-12496.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  85. 2000
  86. Published

    Cubilin P1297L mutation associated with hereditary megaloblastic anemia 1 causes impaired recognition of intrinsic factor-vitamin B(12) by cubilin. / Kristiansen, M; Aminoff, M; Jacobsen, Christian; de La Chapelle, A; Krahe, R; Verroust, P J; Moestrup, Søren Kragh.

    In: Blood, Vol. 96, No. 2, 2000, p. 405-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  87. Published

    Cubilin and megalin mediated uptake of albumin in cultured proximal tubule cells of Opossum kidney. / Zhai, Xiao Yue; Nielsen, Rikke; Birn, Henrik; Drumm, K.; Mildenberger, S.; Freudinger, R.; Moestrup, Søren Kragh; Verroust, P.J.; Christensen, Erik Ilsø; Gekle, M.

    In: Kidney International, Vol. 58, 2000, p. 1523-1533.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  88. Published

    Cubilin is an albumin binding protein important for renal tubular albumin reabsorption. / Birn, Henrik; Fyfe, J.C.; Jacobsen, Christian; Mounier, F.; Verroust, P.J.; Ørskov, Hans; Willnow, T.E.; Moestrup, Søren Kragh; Christensen, Erik Ilsø.

    In: J. Clin. Invest., Vol. 105, 2000, p. 1353-1361.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  89. Published

    Evidence for the role of megalin in renal reabsorption of transthyretin. / Sousa, M.M.; Norden, A.G.; Jacobsen, Christian; Willnow, T.E.; Christensen, Erik Ilsø; Verroust, P.J.; Moestrup, Søren Kragh; Saraiva, M.J.

    In: Journal of Biological Chemistry, Vol. 275, 2000, p. 38176-38181.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  90. Published

    Identification of the minimal functional unit in the low density lipoprotein receptor-related protein for binding the receptor-associated protein (RAP). / Andersen, O.M.; Christensen, L.L.; Christensen, P.A.; Sørensen, E.S.; Jacobsen, Christian; Moestrup, Søren Kragh; Etzerodt, M.; Thøgersen, H.C.

    In: Journal of Biological Chemistry, Vol. 275, No. 28, 2000, p. 21017-21024.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  91. Published

    Mutational analysis of affinity and selectivity of kringle-tetranectin interaction : Grafting novel kringle affinity onto the tetranectin scaffold. / Graversen, J.H.; Jacobsen, Christian; Sigurskjold, B.W.; Lorentzen, R.H.; Moestrup, Søren Kragh; Thøgersen, H.C.; Etzerodt, M.

    In: Journal of Biological Chemistry, Vol. 275, No. 48, 2000, p. 37390-37396.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  92. Published

    Physiopathological role of cubilin and megalin. / Verroust, P.J.; Kozyraki, R.; Hammond, T.G.; Moestrup, Søren Kragh; Christensen, Erik Ilsø.

    Advances in Nephrology. ed. / Grünfeld; Kreis; Bach; Maxwell. Mosby, 2000. p. 127-145.

    Research output: Contribution to book/anthology/report/proceedingReview

  93. Published

    Receptor associated protein is important for normal processing of megalin in kidney proximal tubules. / Birn, Henrik; Vorum, Henrik; Verroust, P.J.; Moestrup, Søren Kragh; Christensen, Erik Ilsø.

    In: Journal of the American Society of Nephrology, Vol. 11, 2000, p. 191-202.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  94. Published

    Rôle physiopathologique de la cubilin et de la mégalin. / Verroust, P.J.; Kozyraki, R.; Hammond, T.G.; Moestrup, Søren Kragh; Christensen, Erik Ilsø.

    Actualités Néphrologiques 2000 de l`Hôpital Necker. ed. / J.P. Grünfeld. Flammarion, 2000. p. 271-285.

    Research output: Contribution to book/anthology/report/proceedingReview

  95. Published

    Specific binding of α-macroglobulin to complement-type repeat CR4 of the low-density lipoprotein receptor-related protein. / Andersen, O.M.; Christensen, P.A.; Christensen, L.L.; Jacobsen, Christian; Moestrup, Søren Kragh; Etzerodt, M.; Thøgersen, H.C.

    In: Biochemistry, Vol. 39, No. 35, 2000, p. 10627-10633.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  96. 1999
  97. Published

    Evidence for an essential role of megalin in transepithelial transport of retinol. / Christensen, Erik Ilsø; Moskaug, J.Ø.; Vorum, Henrik; Jacobsen, Christian; Gundersen, T.E.; Nykjær, Anders; Blomhoff, R.; Willnow, T.E.; Moestrup, Søren Kragh.

    In: Journal of the American Society of Nephrology, Vol. 10, 1999, p. 685-695.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  98. Published

    Megalin antagonizes activation of the parathyroid hormone receptor. / Hilpert, J; Nykjær, Anders; Jacobsen, Christian; Wallukat, G; Nielsen, Rikke; Moestrup, Søren Kragh; Haller, H; Luft, F.C.; Christensen, Erik Ilsø; Willnow, T.E.

    In: Journal of Biological Chemistry, Vol. 274, 1999, p. 5620-5625.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  99. Published

    Molecular dissection of the intrinsic factor-vitamin B12 receptor, cubilin, discloses regions important for membrane association and ligand binding. / Kristiansen, M; Kozyraki, R; Jacobsen, Christian; Nexø, E; Verroust, P J; Moestrup, S K.

    In: Journal of Biological Chemistry, Vol. 274, No. 29, 1999, p. 20540-4.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  100. Published

    Mutations in CUBN, encoding the intrinsic factor-vitamin B12 receptor, cubilin, cause hereditary megaloblastic anaemia 1. / Aminoff, M.; Carter, J.E.; Chadwick, R.B.; Johnson, C.; Gräsbeck, R.; Abdelaal, M.A.; Broch, H.; Jenner, Lasse Bohl; Verroust, P.J.; Moestrup, Søren Kragh; Chapelle, A.; Krahe, R.

    In: Nature Genetics, Vol. 21, 1999, p. 309-313.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  101. Published

    Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding. / Petersen, Claus Munck; Nielsen, Morten Schallburg; Jacobsen, Christian; Tauris, Jacob; Jacobsen, L.; Gliemann, Jørgen; Moestrup, Søren Kragh; Madsen, Peder Søndergaard.

    In: E M B O Journal, Vol. 18, 1999, p. 595-604.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  102. Published

    The intrinsic factor-vitamin B12 receptor, cubilin, is a novel high affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein. / Kozyraki, R.; Fyfe, J.; Kristiansen, M.; Gerdes, C.; Jacobsen, Christian; Cui, S.; Christensen, Erik Ilsø; Aminoff, M.; De La Chapelle, A.; Krahe, R.; Moestrup, Søren Kragh.

    In: Nature Medicine, Vol. 5, 1999, p. 656-661.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  103. 1998
  104. Published

    The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins. / Moestrup, S K; Kozyraki, R; Madsen, M; Kaysen, J H; Rasmussen, H H; Brault, D; Pontillon, F; Goda, F O; Christensen, E I; Hammond, T G; Verroust, P J.

    In: The Journal of biological chemistry, Vol. 273, No. 9, 27.02.1998, p. 5235-42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  105. Published

    Activation of 2'-5' oligoadenylate synthetase by single-stranded and double-stranded RNA aptamers. / Hartmann, R; Norby, P L; Martensen, P M; Jorgensen, P; James, M C; Jacobsen, Christian; Moestrup, S K; Clemens, M J; Justesen, J.

    In: Journal of Biological Chemistry, Vol. 273, No. 6, 1998, p. 3236-46.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  106. Published

    Characterization of a kidney proximal tubule cell line, LLCPK1, expressing endocytotic active megalin. / Nielsen, Rikke; Birn, Henrik; Moestrup, S.K.; Nielsen, M.S.; Verroust, P; Christensen, Erik Ilsø.

    In: Journal of the American Society of Nephrology, Vol. 9, 1998, p. 1767-1776.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  107. Published

    Megalin mediated endocytosis in renal proximal tubule. / Christensen, Erik Ilsø; Birn, Henrik; Verroust, P.; Moestrup, Søren Kragh.

    In: Renal Failure, Vol. 20, 1998, p. 191-199.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  108. Published

    Membrane receptors for endocytosis in renal proximal tubule. / Christensen, Erik Ilsø; Birn, Henrik; Verroust, P.; Moestrup, Søren Kragh.

    In: Int. Rev. Cytol., Vol. 180, 1998, p. 237-284.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  109. Published

    Sortilin is the major 110-kDa protein in GLUT4 vesicles from adipocytes. / Morris, N J; Ross, Steven; Lane, W S; Moestrup, S K; Petersen, C M; Keller, Søren; Lienhard, G E.

    In: Journal of Biological Chemistry, Vol. 273, No. 6, 1998, p. 3582-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  110. Published

    The carboxy-terminal domain of the receptor-associated protein binds to the Vps10p domain of sortilin. / Tauris, Jacob; Ellgaard, L.; Jacobsen, Christian; Nielsen, Morten Schallburg; Madsen, Peder Søndergaard; Thøgersen, Hans Christian; Gliemann, Jørgen; Petersen, Claus Munck; Moestrup, Søren Kragh.

    In: F E B S Letters, Vol. 429, No. 1, 1998, p. 27-30.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review