Søren Egedal Degn

  1. 2020
  2. E-pub ahead of print

    Seeing the Confetti Colors in a New Light Utilizing Flow Cytometry and Imaging Flow Cytometry. / Hagert, Cecilia Fahlquist; Bohn, Anja Bille; Wittenborn, Thomas R; Degn, Søren E.

    In: Cytometry. Part A, 27.05.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. 2019
  4. Published

    Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB. / van der Poel, Cees E.; Bajic, Goran; Macaulay, Charles W.; van den Broek, Theo; Ellson, Christian D.; Bouma, Gerben; Victora, Gabriel D.; Degn, Søren E.; Carroll, Michael C.

    In: Cell Reports, Vol. 29, No. 9, 2019, p. 2745-2755.e4.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity. / Wittenborn, Thomas R.; Hagert, Cecilia; Degn, Søren E.

    In: Journal of visualized experiments : JoVE, No. 146, e59397, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. 2018
  7. Published

    Clinical and immunological parameters of Sjögren's syndrome. / Psianou, Konstantia; Panagoulias, Ioannis; Papanastasiou, Anastasios D; de Lastic, Anne-Lise; Rodi, Maria; Spantidea, Panagiota I; Degn, Søren E; Georgiou, Panagiotis; Mouzaki, Athanasia.

    In: Autoimmunity Reviews, Vol. 17, No. 10, 18.10.2018, p. 1053-1064.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  8. Published

    Capturing change in clonal composition amongst single mouse germinal centers. / Firl, Daniel J; Degn, Soren E; Padera, Timothy; Carroll, Michael C.

    In: eLife, Vol. 7, e33051, 01.08.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    B cell tolerance to epidermal ribonuclear-associated neo-autoantigen in vivo. / Degn, Søren Egedal; Alicot, E; Carroll, M.C.

    In: Clinical and Experimental Immunology, Vol. 191, No. 2, 02.2018, p. 151-165.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. 2017
  11. Published

    Targeting autoreactive germinal centers to curb autoimmunity. / Degn, Søren Egedal; van der Poel, Cees E.; Carroll, Michael C.

    In: OncoTarget, Vol. 8, No. 53, 09.10.2017, p. 90624.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleCommunication

  12. Published

    Clonal Evolution of Autoreactive Germinal Centers. / Degn, Søren Egedal; van der Poel, Cees E.; Firl, Daniel J.; Ayoglu, Burcu; Al Qureshah, Fahd A.; Bajic, Goran; Mesin, Luka; Reynaud, Claude-Agnès; Weill, Jean-Claude; Utz, Paul J.; Victora, Gabriel D.; Carroll, Michael C.

    In: Cell, Vol. 170, No. 5, 24.08.2017, p. 913-926.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Endogenous Natural Complement Inhibitor Regulates Cardiac Development. / Mortensen, Simon A; Skov, Louise L; Kjaer-Sorensen, Kasper; Hansen, Annette G; Hansen, Søren; Dagnæs-Hansen, Frederik; Jensenius, Jens C; Oxvig, Claus; Thiel, Steffen; Degn, Søren E.

    In: Journal of Immunology, Vol. 198, No. 8, 15.04.2017, p. 3118-3126.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. 2015
  15. Published

    Complement activation, regulation, and molecular basis for complement-related diseases. / Bajic, Goran; Degn, Søren E; Thiel, Steffen; Andersen, Gregers R.

    In: E M B O Journal, Vol. 34, No. 22, 21.10.2015, p. 2735-2757.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  16. 2014
  17. Published

    Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes. / Degn, Søren E; Kjaer, Troels R; Kidmose, Rune Thomas; Jensen, Lisbeth; Hansen, Annette G; Tekin, Mustafa; Jensenius, Jens C; Andersen, Gregers R; Thiel, Steffen.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 37, 02.09.2014, p. 13445-13450.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    The pro-factor D cleaving activity of MASP-1/-3 is not required for alternative pathway function. / Degn, Søren E; Jensenius, Jens C; Thiel, Steffen.

    In: Journal of Immunology, Vol. 192, No. 12, 15.06.2014, p. 5447-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. 2013
  20. Published

    Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner. / Chatterjee, Priyadarshini; Agyemang, Amma F; Alimzhanov, Marat B; Degn, Søren Egedal; Tsiftsoglou, Stefanos A; Alicot, Elisabeth; Jones, Sarah A; Ma, Minghe; Carroll, Michael C.

    In: European Journal of Immunology, Vol. 43, No. 9, 09.2013, p. 2441-50.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Co-complexes of MASP-1 and MASP-2 associated with the soluble pattern-recognition molecules drive lectin pathway activation in a manner inhibitable by MAp44. / Degn, Søren E; Jensen, Lisbeth; Olszowski, Tomasz; Jensenius, Jens C; Thiel, Steffen.

    In: Journal of Immunology, Vol. 191, No. 3, 01.08.2013, p. 1334-45.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Humoral pattern recognition and the complement system. / Degn, S E; Thiel, Steffen.

    In: Scandinavian Journal of Immunology, Vol. 78, No. 2, 08.2013, p. 181-93.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Response to comment on "Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function". / Degn, Søren E; Jensenius, Jens C; Thiel, Steffen.

    In: Journal of Immunology, Vol. 190, No. 6, 15.03.2013, p. 2477-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Mitochondria and the lectin pathway of complement. / Brinkmann, Christel R; Jensen, Lisbeth; Dagnaes-Hansen, Frederik; Holm, Ida E; Endo, Yuichi; Fujita, Teizo; Thiel, Steffen; Jensenius, Jens C; Degn, Søren E.

    In: Journal of Biological Chemistry, 2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Recombinant expression of the autocatalytic complement protease MASP-1 is crucially dependent on co-expression with its inhibitor, C1 inhibitor. / Degn, Søren E; Thiel, Steffen; Jensenius, Jens C.

    In: Protein Expression and Purification, Vol. 88, No. 2, 2013, p. 173-182.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. 2012
  27. Published

    Mannan-Binding Lectin-Associated Serine Protease (MASP)-1 Is Crucial for Lectin Pathway Activation in Human Serum, whereas neither MASP-1 nor MASP-3 Is Required for Alternative Pathway Function. / Degn, Søren Egedal; Jensen, Lisbeth; Hansen, Annette G; Duman, Duygu; Tekin, Mustafa; Jensenius, Jens C; Thiel, Steffen.

    In: Journal of Immunology, Vol. 189, No. 8, 2012, p. 3957-69.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules : normal and acute-phase levels in serum and stoichiometry of lectin pathway components. / Thiel, S; Jensen, L; Degn, Søren Egedal; Nielsen, Hans Jørgen; Gál, Peter; Dobó, Joseph; Jensenius, J C.

    In: Clinical and Experimental Immunology. Supplement, Vol. 169, No. 1, 2012, p. 38-48.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. 2011
  30. Published

    Assay interference caused by antibodies reacting with rat kappa light-chain in human sera. / Degn, Søren Egedal; Andersen, Stig Henrik; Jensen, Lisbeth; Thiel, Steffen; Jensenius, Jens C.

    In: Journal of Immunological Methods, Vol. 372, No. 1-2, 2011, p. 204-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    Disease-causing mutations in genes of the complement system. / Degn, Søren E; Jensenius, Jens Christian; Thiel, Steffen.

    In: American Journal of Human Genetics, Vol. 88, No. 6, 2011, p. 689-705.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    MAp19, the alternative splice product of the MASP2 gene. / Degn, Søren Egedal; Thiel, Steffen; Nielsen, Ole; Hansen, Annette G; Steffensen, Rudi; Jensenius, Jens C.

    In: Journal of Immunological Methods, Vol. 373, No. 1-2, 2011, p. 89-101.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Trafficking of B cell antigen in lymph nodes. / Gonzalez, Santiago F.; Degn, Søren Egedal; Pitcher, Lisa A.; Woodruff, Matthew; Heesters, Balthasar A.; Carroll, Michael C.

    In: Annual Review of Immunology, Vol. 29, 2011, p. 215-233.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. 2010
  35. Published

    The lectin pathway and its implications in coagulation, infections and auto-immunity. / Degn, Søren E; Jensenius, Jens C; Bjerre, Mette.

    In: Current Opinion in Organ Transplantation, 09.12.2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system. / Degn, Søren E; Jensen, Lisbeth; Gál, Péter; Dobó, József; Holmvad, Steffen H; Jensenius, Jens C; Thiel, Steffen.

    In: Journal of Immunological Methods, Vol. 361, No. 1-2, 30.09.2010, p. 37-50.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes. / Gonzalez, Santiago F.; Lukacs-Kornek, Veronika; Kuligowski, Michael P.; Pitcher, Lisa A.; Degn, Søren Egedal; Kim, Young-A; Cloninger, Mary J.; Martinez-Pomares, Luisa; Gordon, Siamon; Turley, Shannon J.; Carroll, Michael C.

    In: Nature Immunology, Vol. 11, No. 5, 05.2010, p. 427-435.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    Complement-dependent transport of antigen into B cell follicles. / Gonzalez, Santiago F.; Lukacs-Kornek, Veronika; Kuligowski, Michael P.; Pitcher, Lisa A.; Degn, Søren Egedal; Turley, Shannon J.; Carroll, Michael C.

    In: Journal of Immunology, Vol. 185, 2010, p. 2659-2664.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    The Lectin Pathway Serine Proteases and Associated Proteins. / Degn, Søren Egedal.

    Århus Universitet, 2010.

    Research output: Book/anthology/dissertation/reportPh.D. thesisResearch

  40. 2009
  41. Published

    MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activation. / Degn, Søren Egedal; Hansen, Annette; Steffensen, Rudi; Jacobsen, Christian; Jensenius, Jens C; Thiel, Steffen.

    In: Journal of Immunology, Vol. 183, No. 11, 2009, p. 7371-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    Polymorphisms in mannan-binding lectin (MBL)-associated serine protease 2 affect stability, binding to MBL, and enzymatic activity. / Thiel, Steffen; Kolev, Martin; Degn, Søren Egedal; Steffensen, Rudi; Hansen, Annette; Ruseva, Marieta; Jensenius, Jens C.

    In: Journal of Immunology, Vol. 182, No. 5, 2009, p. 2939-47.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. 2007
  44. Published

    New perspectives on mannan-binding lectin-mediated complement activation. / Degn, Søren Egedal; Thiel, Steffen; Jensenius, Jens Christian.

    In: Immunobiology, Vol. 212, 2007, p. 301-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review