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Signe Maria Nielsen

Innate glycosidic activity in metallic implants for localized synthesis of antibacterial drugs

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Standard

Innate glycosidic activity in metallic implants for localized synthesis of antibacterial drugs. / Meer, Marja Ter; Dillion, Ross; Nielsen, Signe Maria; Walther, Raoul; Meyer, Rikke L.; Daamen, Willeke F.; Van Den Heuvel, Lambertus P.; Van Der Vliet, J. Adam; Lomme, Roger M.L.M.; Hoogeveen, Yvonne L.; Schultze Kool, Leo J.; Schaffer, Jeremy E.; Zelikin, Alexander N.

In: Chemical Communications, Vol. 55, No. 4, 01.01.2019, p. 443-446.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Meer, MT, Dillion, R, Nielsen, SM, Walther, R, Meyer, RL, Daamen, WF, Van Den Heuvel, LP, Van Der Vliet, JA, Lomme, RMLM, Hoogeveen, YL, Schultze Kool, LJ, Schaffer, JE & Zelikin, AN 2019, 'Innate glycosidic activity in metallic implants for localized synthesis of antibacterial drugs', Chemical Communications, vol. 55, no. 4, pp. 443-446. https://doi.org/10.1039/c8cc08737g

APA

Meer, M. T., Dillion, R., Nielsen, S. M., Walther, R., Meyer, R. L., Daamen, W. F., Van Den Heuvel, L. P., Van Der Vliet, J. A., Lomme, R. M. L. M., Hoogeveen, Y. L., Schultze Kool, L. J., Schaffer, J. E., & Zelikin, A. N. (2019). Innate glycosidic activity in metallic implants for localized synthesis of antibacterial drugs. Chemical Communications, 55(4), 443-446. https://doi.org/10.1039/c8cc08737g

CBE

Meer MT, Dillion R, Nielsen SM, Walther R, Meyer RL, Daamen WF, Van Den Heuvel LP, Van Der Vliet JA, Lomme RMLM, Hoogeveen YL, Schultze Kool LJ, Schaffer JE, Zelikin AN. 2019. Innate glycosidic activity in metallic implants for localized synthesis of antibacterial drugs. Chemical Communications. 55(4):443-446. https://doi.org/10.1039/c8cc08737g

MLA

Vancouver

Author

Meer, Marja Ter ; Dillion, Ross ; Nielsen, Signe Maria ; Walther, Raoul ; Meyer, Rikke L. ; Daamen, Willeke F. ; Van Den Heuvel, Lambertus P. ; Van Der Vliet, J. Adam ; Lomme, Roger M.L.M. ; Hoogeveen, Yvonne L. ; Schultze Kool, Leo J. ; Schaffer, Jeremy E. ; Zelikin, Alexander N. / Innate glycosidic activity in metallic implants for localized synthesis of antibacterial drugs. In: Chemical Communications. 2019 ; Vol. 55, No. 4. pp. 443-446.

Bibtex

@article{df8941a9f777455f8db5915e0fc48b98,
title = "Innate glycosidic activity in metallic implants for localized synthesis of antibacterial drugs",
abstract = "Iron-containing metallic implants are shown herein to mediate hydrolysis of glycosidic linkages. Using glucuronide prodrugs for broad-spectrum fluoroquinolone antibacterial agents, we capitalize on this behaviour and perform localized synthesis of antimicrobials which affords a significant zone of inhibition of bacterial growth around the metallic material.",
author = "Meer, {Marja Ter} and Ross Dillion and Nielsen, {Signe Maria} and Raoul Walther and Meyer, {Rikke L.} and Daamen, {Willeke F.} and {Van Den Heuvel}, {Lambertus P.} and {Van Der Vliet}, {J. Adam} and Lomme, {Roger M.L.M.} and Hoogeveen, {Yvonne L.} and {Schultze Kool}, {Leo J.} and Schaffer, {Jeremy E.} and Zelikin, {Alexander N.}",
year = "2019",
month = jan,
day = "1",
doi = "10.1039/c8cc08737g",
language = "English",
volume = "55",
pages = "443--446",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "ROYAL SOC CHEMISTRY",
number = "4",

}

RIS

TY - JOUR

T1 - Innate glycosidic activity in metallic implants for localized synthesis of antibacterial drugs

AU - Meer, Marja Ter

AU - Dillion, Ross

AU - Nielsen, Signe Maria

AU - Walther, Raoul

AU - Meyer, Rikke L.

AU - Daamen, Willeke F.

AU - Van Den Heuvel, Lambertus P.

AU - Van Der Vliet, J. Adam

AU - Lomme, Roger M.L.M.

AU - Hoogeveen, Yvonne L.

AU - Schultze Kool, Leo J.

AU - Schaffer, Jeremy E.

AU - Zelikin, Alexander N.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Iron-containing metallic implants are shown herein to mediate hydrolysis of glycosidic linkages. Using glucuronide prodrugs for broad-spectrum fluoroquinolone antibacterial agents, we capitalize on this behaviour and perform localized synthesis of antimicrobials which affords a significant zone of inhibition of bacterial growth around the metallic material.

AB - Iron-containing metallic implants are shown herein to mediate hydrolysis of glycosidic linkages. Using glucuronide prodrugs for broad-spectrum fluoroquinolone antibacterial agents, we capitalize on this behaviour and perform localized synthesis of antimicrobials which affords a significant zone of inhibition of bacterial growth around the metallic material.

UR - http://www.scopus.com/inward/record.url?scp=85059500734&partnerID=8YFLogxK

U2 - 10.1039/c8cc08737g

DO - 10.1039/c8cc08737g

M3 - Journal article

C2 - 30489589

AN - SCOPUS:85059500734

VL - 55

SP - 443

EP - 446

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 4

ER -