Research output per year
Research output per year
- 25 results
Search results
-
2025
Genetic Landscape and Mitochondrial Metabolic Dysregulation in Patients Suffering From Severe Long COVID
Hansen, K. S., Jørgensen, S. E., Cömert, C., Schiøttz-Christensen, B., Bross, P., Agergaard, J., Leth, S., Østergaard, L., Palmfeldt, J., Olsen, R. K. J. & Mogensen, T. H., Mar 2025, In: Journal of Medical Virology. 97, 3, e70275.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
2023
A Novel CDC42 Variant with Impaired Thymopoiesis, IL-7R Signaling, PAK1 Binding, and TCR Repertoire Diversity
Assing, K., Jørgensen, S. E., Sandgaard, K. S., De Keukeleere, K., B.-Hansen, M., Petersen, M. S., Hartling, U. B., Vaal, T. M. K. D., Nielsen, C., Jakobsen, M. A., Watt, E., Adams, S., Hao, Q., Fagerberg, C. & Mogensen, T. H., Nov 2023, In: Journal of Clinical Immunology. 43, 8, p. 1927-1940 14 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile8 Downloads (Pure) -
Autoantibodies Neutralizing Type III Interferons Are Uncommon in Patients with Severe Coronavirus Disease 2019 Pneumonia
Vanker, M., Särekannu, K., Fekkar, A., Jørgensen, S. E., Haljasmägi, L., Kallaste, A., Kisand, K., Lember, M., Peterson, P., Menon, M., Hussell, T., Knight, S., Moore-Stanley, J., Bastard, P., Zhang, S. Y., Mogensen, T. H., Philippot, Q., Zhang, Q., Puel, A. & Casanova, J. L. & 1 others, , 1 Sept 2023, In: Journal of Interferon & Cytokine Research. 43, 9, p. 379-393 15 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus) -
Examination of autoantibodies to type I interferon in patients suffering from long COVID
Hansen, K. S., Jørgensen, S. E., Skouboe, M. K., Agergaard, J., Schiøttz-Christensen, B., Vibholm, L. K., Tolstrup, M., Østergaard, L., Leth, S. & Mogensen, T. H., Sept 2023, In: Journal of Medical Virology. 95, 9, 7 p., e29089.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile5 Citations (Scopus) -
Myopathy as a cause of Long COVID fatigue: Evidence from quantitative and single fiber EMG and muscle histopathology
Agergaard, J., Yamin Ali Khan, B., Engell-Sørensen, T., Schiøttz-Christensen, B., Jørgen Østergaard, L., Hejbøl, E. K., Schrøder, H. D., Andersen, H., Blicher, J. U., Holm Pedersen, T., Harbo, T., Tankisi, H. & MULTICOV Consortium, Apr 2023, In: Clinical Neurophysiology. 148, p. 65-75 11 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile16 Citations (Scopus)22 Downloads (Pure) -
2022
Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic
Duncan, C. J. A., Skouboe, M. K., Howarth, S., Hollensen, A. K., Chen, R., Børresen, M. L., Thompson, B. J., Stremenova Spegarova, J., Hatton, C. F., Stæger, F. F., Andersen, M. K., Whittaker, J., Paludan, S. R., Jørgensen, S. E., Thomsen, M. K., Mikkelsen, J. G., Heilmann, C., Buhas, D., Øbro, N. F. & Bay, J. T. & 17 others, , Jun 2022, In: The Journal of Experimental Medicine. 219, 6, 22 p., e20212427.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile54 Citations (Scopus)29 Downloads (Pure) -
Postpartum Disseminated Herpes Simplex Virus Type 1 Infection With Hemophagocytic Lymphohistiocytosis and Fulminant Neonatal Herpes Infection
Freytag, M. R., Jørgensen, S. E., Thomsen, M. M., Al-Mousawi, A., Hait, A. S., Olagnier, D., Bay, J. T., Helleberg, M. & Mogensen, T. H., 1 Jan 2022, In: The Journal of Infectious Diseases. 225, 1, p. 157-162 6 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
5 Citations (Scopus) -
2021
Essential role of autophagy in restricting poliovirus infection revealed by identification of an ATG7 defect in a poliomyelitis patient
Brinck Andersen, N. S., Jørgensen, S. E., Skipper, K. A., Larsen, S. M., Heinz, J., Thomsen, M. M., Farahani, E., Cai, Y., Hait, A. S., Kay, L., Giehm Mikkelsen, J., Høgsbjerg Schleimann, M., Thomsen, M. K., Paludan, S. R. & Mogensen, T. H., Sept 2021, In: Autophagy. 17, 9, p. 2449-2464 16 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access9 Citations (Scopus) -
Fulminant H1N1 and severe acute respiratory syndrome coronavirus-2 infections with a 4-year interval without an identifiable underlying cause: a case report
Katzenstein, T. L., Jørgensen, S. E., Mortensen, J., Helleberg, M., Kalhauge, A. & Mogensen, T. H., Dec 2021, In: Journal of Medical Case Reports. 15, 1, 8 p., 505.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
Host Genetics and Antiviral Immune Responses in Adult Patients With Multisystem Inflammatory Syndrome
Ronit, A., Jørgensen, S. E., Roed, C., Eriksson, R., Iepsen, U. W., Plovsing, R. R., Storgaard, M., Gustafsson, F., Hansen, A. B. E. & Mogensen, T. H., Aug 2021, In: Frontiers in Immunology. 12, 9 p., 718744.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access13 Citations (Scopus) -
STK4 Deficiency Impairs Innate Immunity and Interferon Production Through Negative Regulation of TBK1-IRF3 Signaling
Jørgensen, S. E., Al-Mousawi, A., Assing, K., Hartling, U., Grosen, D., Fisker, N., Nielsen, C., Jakobsen, M. A. & Mogensen, T. H., Jan 2021, In: Journal of Clinical Immunology. 41, 1, p. 109–124 16 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
19 Citations (Scopus) -
2020
Autoinflammatory disease with corneal and mucosal dyskeratosis caused by a novel NLRP1 variant
Herlin, T., Jørgensen, S. E., Høst, C., Mitchell, P. S., Christensen, M. H., Laustsen, M., Larsen, D. A., Schmidt, F. I., Christiansen, M. & Mogensen, T. H., 1 Sept 2020, In: Rheumatology. 59, 9, p. 2334-2339 6 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
23 Citations (Scopus) -
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
Olagnier, D., Farahani, E., Thyrsted, J., Blay-Cadanet, J., Herengt, A., Idorn, M., Hait, A., Hernaez, B., Knudsen, A., Iversen, M. B., Schilling, M., Jørgensen, S. E., Thomsen, M., Reinert, L. S., Lappe, M., Hoang, H.-D., Gilchrist, V. H., Hansen, A. L., Ottosen, R. & Nielsen, C. G. & 18 others, , 1 Dec 2020, In: Nature Communications. 11, 1, 12 p., 4938.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access305 Citations (Scopus) -
Systemic juvenile idiopathic arthritis and recurrent macrophage activation syndrome due to a CASP1 variant causing inflammasome hyperactivation
Jørgensen, S. E., Christiansen, M., Høst, C., Glerup, M., Mahler, B., Lausten, M. M., Gad, H. H., Hartmann, R., Herlin, T. & Mogensen, T. H., 1 Oct 2020, In: Rheumatology (Oxford, England). 59, 10, p. 3099-3105 7 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
14 Citations (Scopus) -
2019
Defective interferon priming and impaired antiviral responses in a patient with an IRF7 variant and severe influenza
Thomsen, M. M., Jørgensen, S. E., Gad, H. H., Storgaard, M., Gjedsted, J., Christiansen, M., Hartmann, R. & Mogensen, T. H., Dec 2019, In: Medical Microbiology and Immunology. 208, 6, p. 869-876 8 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
21 Citations (Scopus) -
Host genetics, innate immune responses, and cellular death pathways in poliomyelitis patients
Andersen, N. S. B., Larsen, S. M., Nissen, S. K., Jørgensen, S. E., Mardahl, M., Christiansen, M., Kay, L. & Mogensen, T. H., Jul 2019, In: Frontiers in Microbiology. 10, 1495.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access10 Citations (Scopus) -
Impaired immune responses to herpesviruses and microbial ligands in patients with MonoMAC
Mardahl, M., Jørgensen, S. E., Schneider, A., Raaschou-Jensen, K., Holm, M., Veirum, J., Kristensen, T. K., Johansen, I. S., Christiansen, M., Assing, K. & Mogensen, T. H., Aug 2019, In: British Journal of Haematology. 186, 3, p. 471-476 6 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
7 Citations (Scopus) -
Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined
Kaleviste, E., Saare, M., Leahy, T. R., Bondet, V., Duffy, D., Mogensen, T. H., Jørgensen, S. E., Nurm, H., Ip, W., Davies, E. G., Sauer, S., Syvänen, A. C., Milani, L., Peterson, P. & Kisand, K., 2019, In: European Journal of Immunology. 49, 5, p. 790-800 11 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
30 Citations (Scopus) -
2018
Defective RNA sensing by RIG-I in severe influenza virus infection
Jørgensen, S. E., Christiansen, M., Ryø, L. B., Gad, H. H., Gjedsted, J., Staeheli, P., Mikkelsen, J. G., Storgaard, M., Hartmann, R. & Mogensen, T. H., Jun 2018, In: Clinical and Experimental Immunology. 192, 3, p. 366-376 11 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access40 Citations (Scopus) -
Whole Exome Sequencing of HIV-1 long-term non-progressors identifies rare variants in genes encoding innate immune sensors and signaling molecules
Nissen, S. K., Christiansen, M., Helleberg, M., Kjær, K., Jørgensen, S. E., Gerstoft, J., Katzenstein, T. L., Benfield, T., Kronborg, G., Larsen, C. S., Laursen, A., Pedersen, G., Jakobsen, M. R., Tolstrup, M. & Mogensen, T. H., 1 Dec 2018, In: Scientific Reports. 8, 1, p. 15253 15253.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access14 Citations (Scopus) -
2016
Ectodermal dysplasia with immunodeficiency caused by a branch-point mutation in IKBKG/NEMO
Jørgensen, S. E., Bøttger, P., Kofod-Olsen, E., Holm, M., Mørk, N., Ørntoft, T. F., Sørensen, U., Bernth-Jensen, J. M., Herlin, T., Veirum, J., Larsen, C. S., Østergaard, L. J., Hartmann, R., Christiansen, M. & Mogensen, T., 1 Dec 2016, In: Journal of Allergy and Clinical Immunology. 138, 6, p. 1706-1709.e4 8 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
13 Citations (Scopus) -
2015
Altered fraction of regulatory B and T cells is correlated with autoimmune phenomena and splenomegaly in patients with CVID
Kofod-Olsen, E., Jørgensen, S. E., Nissen, S. K., Westh, L., Møller, B. K., Østergaard, L., Larsen, C. S. & Mogensen, T. H., 14 Nov 2015, In: Clinical Immunology. 162, p. 49-57 9 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
22 Citations (Scopus) -
Functional IRF3 deficiency in a patient with herpes simplex encephalitis
Andersen, L. L., Mørk, N., Reinert, L. S., Kofod-Olsen, E., Narita, R., Jørgensen, S. E., Skipper, K. A., Höning, K., Gad, H. H., Østergaard, L., Ørntoft, T. F., Hornung, V., Paludan, S. R., Mikkelsen, J. G., Fujita, T., Christiansen, M., Hartmann, R. & Mogensen, T. H., 2015, In: Journal of Experimental Medicine. 212, 9, p. 1371-9 9 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
174 Citations (Scopus) -
2014
Inflammatory Cytokines Break Down Intrinsic Immunological Tolerance of Human Primary Keratinocytes to Cytosolic DNA
Chiliveru, S., Rahbek, S. H., Jensen, S. K., Jørgensen, S. E., Nissen, S. K., Christiansen, S. H., Mogensen, T. H., Jakobsen, M. R., Iversen, L., Johansen, C. & Paludan, S. R., 2014, In: Journal of Immunology.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
46 Citations (Scopus) -
Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway
Hansen, K., Prabakaran, T., Laustsen, A., Jørgensen, S. E., Rahbek, S. H., Jensen, S. B., Nielsen, R., Leber, J. H., Decker, T., Horan, K. A., Jakobsen, M. R. & Paludan, S. R., 1 Aug 2014, In: E M B O Journal. 33, 15, p. 1654-66 13 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
211 Citations (Scopus)