Aarhus University Seal / Aarhus Universitets segl

Seandean Lykke Harwood

  1. 2019
  2. Published

    Carcinoembryonic Antigen (CEA)-Specific 4-1BB-Costimulation Induced by CEA-Targeted 4-1BB-Agonistic Trimerbodies. / Mikkelsen, Kasper; Lykke Harwood, Seandean; Compte, Marta; Merino, Nekane; Molgaard, Kasper; Lykkemark, Simon; Alvarez-Mendez, Ana; Blanco, Francisco J.; Alvarez-Vallina, Luis.

    In: Frontiers in Immunology, Vol. 10, 1791, 07.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. 2018
  4. Published

    A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity. / Compte, Marta; Harwood, Seandean Lykke; Muñoz, Ines G.; Navarro, Rocio; Zonca, Manuela; Perez-Chacon, Gema; Erce-Llamazares, Ainhoa; Merino, Nekane; Tapia-Galisteo, Antonio; Cuesta, Angel M.; Mikkelsen, Kasper; Caleiras, Eduardo; Nuñez-Prado, Natalia; Aznar, M. Angela; Lykkemark, Simon; Martínez-Torrecuadrada, Jorge; Melero, Ignacio; Blanco, Francisco J.; Bernardino de la Serna, Jorge; Zapata, Juan M.; Sanz, Laura; Alvarez-Vallina, Luis.

    In: Nature Communications, Vol. 9, 4809 , 15.11.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Bispecific light T-cell engagers for gene-based immunotherapy of epidermal growth factor receptor (EGFR)-positive malignancies. / Jensen, Kasper; Harwood, Seandean Lykke; Compte, Marta; Merino, Nekane; Bonet, Jaume; Álvarez-Cienfuegos, Ana; Mikkelsen, Kasper; Alanes, Natalia Nuñez del Prado; Álvarez-Méndez, Ana; Sanz, Laura; Blanco, Francisco J; Álvarez-Vallina, Luis.

    In: Cancer Immunology, Immunotherapy, Vol. 67, No. 8, 08.2018, p. 1251-1260.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy. / Harwood, Seandean Lykke; Alvarez-Cienfuegos, Ana; Alanes, Natalia Nuñez del Prado; Compte, Marta; Hernández-Pérez, Sara; Merino, Nekane; Bonet, Jaume; Navarro, Rocio; M.P. van Bergen en Henegouwen, Paul; Lykkemark, Simon; Mikkelsen, Kasper; Mølgaard , Kasper; Jabs, Frederic; Sanz, Laura; Blanco, Francisco J; Roda-Navarro, Pedro; Álvarez-Vallina, Luis.

    In: OncoImmunology, Vol. 7, No. 1, e1377874, 2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. 2017
  8. Published

    Balanced secretion of anti-CEA x anti-CD3 diabody chains using the 2A self-cleaving peptide maximizes diabody assembly and tumor-specific cytotoxicity. / Mølgaard , Kasper; Compte, Marta; Alanes, Natalia Nuñez del Prado; Harwood, Seandean Lykke; Sanz, Laura; Álvarez-Vallina, Luis.

    In: Gene Therapy, Vol. 24, 2017, p. 208-214.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. 2016
  10. Published

    Efficacy and toxicity management of CAR-T cell immunotherapy: a matter of responsiveness control or tumor-specificity? / Alonso-Camino, Vanesa; Harwood, Seandean Lykke; Alvarez-Méndez, Ana M; Álvarez-Vallina, Luis.

    In: Biochemical Society. Transactions, Vol. 44, No. 2, 2016, p. 406-411.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains. / Álvarez-Cienfuegos, Ana; Alanes, Natalia Nuñez del Prado; Compte, Marta; Cuesta, Àngel M; Blanco-Toribio, Ana; Harwood, Seandean Lykke; Villate, Maider; Merino, Nekane; Bonet, Jaume; Navarro, Rocio; Muñoz-Briones, Clara; Sørensen, Karen Marie Juul; Mølgaard, Kasper; Oliva, Baldomero; Sanz, Laura; Blanco, Francisco J; Álvarez-Vallina, Luis.

    In: Scientific Reports, Vol. 6, 28643, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review