Department of Clinical Medicine

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Rikke Hahn Kofoed

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  1. 2023
  2. Published
    Sonoselective delivery using ultrasound and microbubbles combined with intravenous rAAV9 CLDN5-GFP does not increase endothelial gene expression. / Kofoed, Rikke Hahn; Simpson, Elizabeth M.; Hynynen, Kullervo et al.
    In: Gene Therapy, 2023.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  3. 2022
  4. Published
    The engineered AAV2-HBKO promotes non-invasive gene delivery to large brain regions beyond ultrasound targeted sites. / Kofoed, Rikke Hahn; Noseworthy, Kate; Wu, Kathleen et al.
    In: Molecular Therapy - Methods and Clinical Development, Vol. 27, 08.12.2022, p. 167-184.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  5. Published
    Efficacy of gene delivery to the brain using AAV and ultrasound depends on serotypes and brain areas. / Kofoed, Rikke Hahn; Dibia, Chinaza Lilian; Noseworthy, Kate et al.
    In: Journal of Controlled Release, Vol. 351, 11.2022, p. 667-680.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  6. 2021
  7. Published
    Transgene distribution and immune response after ultrasound delivery of rAAV9 and PHP.B to the brain in a mouse model of amyloidosis. / Kofoed, Rikke Hahn; Heinen, Stefan; Silburt, Joseph et al.
    In: Molecular Therapy - Methods and Clinical Development, Vol. 23, 10.12.2021, p. 390-405.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  8. Published
    Systemic AAV6-synapsin-GFP administration results in lower liver biodistribution, compared to AAV1&2 and AAV9, with neuronal expression following ultrasound-mediated brain delivery. / Weber-Adrian, Danielle; Kofoed, Rikke Hahn; Silburt, Joseph et al.
    In: Scientific Reports, Vol. 11, No. 1, 1934, 12.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  9. Published
    PKR kinase directly regulates tau expression and Alzheimer's Disease-related tau phosphorylation. / Reimer, Lasse; Betzer, Cristine; Kofoed, Rikke Hahn et al.
    In: Brain Pathology, Vol. 31, No. 1, 01.2021, p. 103-119.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  10. Published
    Viral alpha-synuclein knockdown prevents spreading synucleinopathy. / Menon, Sindhu; Kofoed, Rikke H.; Nabbouh, Fadl et al.
    In: Brain Communications, Vol. 3, No. 4, 247, 2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  11. 2020
  12. Published
    Glycogen synthase kinase 3 β activity is essential for Polo-like kinase 2- and Leucine-rich repeat kinase 2-mediated regulation of α-synuclein. / Kofoed, Rikke H; Betzer, Cristine; Ferreira, Nelson et al.
    In: Neurobiology of Disease, Vol. 136, 104720, 03.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  13. Published
    Focused ultrasound as a novel strategy for noninvasive gene delivery to retinal Müller glia. / Touahri, Yacine; Dixit, Rajiv; Kofoed, Rikke Hahn et al.
    In: Theranostics, Vol. 10, No. 7, 2020, p. 2982-2999.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  14. 2019
  15. Published
    Strategy to enhance transgene expression in proximity of amyloid plaques in a mouse model of Alzheimer's disease. / Weber-Adrian, Danielle; Kofoed, Rikke Hahn; Chan, Josephine Wing Yee et al.
    In: Theranostics, Vol. 9, No. 26, 2019, p. 8127-8137.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  16. Published
    The use of co-immunoprecipitation to study conformation-specific protein interactions of oligomeric α-synuclein aggregates. / Betzer, Cristine; Kofoed, Rikke Hahn; Jensen, Poul Henning.
    Neuromethods : co-immunoprecipitation methods for brain tissue. New York: Humana Press, 2019. p. 23-36 (Neuromethods, Vol. 144).

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Education › peer-review

  17. 2018
  18. Published
    Investigation of RNA Synthesis Using 5-Bromouridine Labelling and Immunoprecipitation. / Kofoed, Rikke H; Betzer, Cristine; Lykke-Andersen, Søren et al.
    In: Journal of Visualized Experiments, No. 135, 03.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  19. Published
    Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation. / Betzer, Cristine; Lassen, Louise Berkhoudt; Olsen, Anders et al.
    In: EMBO Reports, Vol. 19, No. 5, e44617, 01.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  20. Published
    Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death. / Reimer, Lasse; Lund, Louise Buur; Betzer, Cristine et al.
    In: Neurobiology of Disease, 01.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  21. Published
    ELISA method to detect α-synuclein oligomers in cell and animal models. / Lassen, Louise Berkhoudt; Gregersen, Emil; Isager, Anne Kathrine et al.
    In: PLOS ONE, Vol. 13, No. 4, e0196056, 26.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  22. 2017
  23. Published
    Polo-like kinase 2 modulates α-synuclein protein levels by regulating its mRNA production. / Kofoed, Rikke H; Zheng, Jin; Ferreira, Nelson et al.
    In: Neurobiology of Disease, Vol. 106, 17.10.2017, p. 49-62.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  24. Published
    SOLUBLE AGGREGATES OF ALPHA-SYNUCLEIN ACTIVATE SERCA CAUSING CALCIUM DYSREGULATION. / Betzer, Cristine; Lassen, Louise Berkhoudt; Möller, Arne et al.
    2017. Poster session presented at 20 years of alpha-synuclein in Parkinson's disease and related synucleinopathies, Greece.

    Research output: Contribution to conference › Poster › Research

  25. Published
    SOLUBLE AGGREGATES OF ALPHA-SYNUCLEIN ACTIVATES SERCA CAUSING CALCIUM DYSREGULATION. / Betzer, Cristine; Lassen, Louise Berkhoudt; Möller, Arne et al.
    2017. Poster session presented at AD/PD 2017 , Vienna, Austria.

    Research output: Contribution to conference › Poster › Research