Renée Marije van der Sluis
PhD, Assistant Professor, AIAS-COFUND Fellow
Department of Biomedicine - Forskning og uddannelse, Skou-bygningen
Høegh-Guldbergs Gade 10
building 1115, 218
8000 Aarhus C
Denmark
Aarhus Institute of Advanced Studies
Høegh-Guldbergs Gade 6B
8000 Aarhus C
Denmark
Research areas
- Nature and Technology > Molecular Biology and Biotechnology > HIV and other retroviruses HIV latency HIV latency reversing agents
- Nature and Technology > Molecular Biology and Biotechnology > Immune system Immunomodulation to treat HIV infection immune checkpoint molecules PD-1 CTLA-4 TIGIT Tim-3
- Nature and Technology > Molecular Biology and Biotechnology > Signals between and inside cells dendritic cells mDC pDC CD4+ T cells CD8+ T cells NK type I IFNs
Profile
Renee obtained her PhD in 2013 from the University of Amsterdam and promptly moved across the world to do research in Melbourne. In 2018 she returned to Europe to work in Denmark at the University of Aarhus. Throughout her career Renee focusses her research on 1) how HIV establishes a latent infection in CD4+ T cells, and thereby evades detection by the immune system, 2) how the interaction of infected cells with other immune cells, particularly dendritic cells, affect virus expression and finally, 3) how the immune system can be manipulated to ultimately eliminate HIV infected cells from the infected individual to facilitate virus remission so that antiviral therapy may be stopped.
- Published
Efficient HIV latency reversal with immune checkpoint blockade in a primary T-cell latency model.
Research output: Contribution to conference › Poster › Research › peer-review
- E-pub ahead of print
Modulation of the CCR5 receptor/ligand axis by seminal plasma and the utility of in vitro versus in vivo models
Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
- E-pub ahead of print
CD4- and time-dependent susceptibility of HIV-1-infected cells to ADCC
Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Frontiers in cellular and infection microbiology (Journal)
Activity: Publication peer-review and editorial work types › Editor of Research journal › Research
Efficient HIV latency reversal with immune checkpoint blockade in a primary T-cell latency model.
Activity: Talk or presentation types › Lecture and oral contribution
European Congress of Virology 2019
Activity: Participating in or organising an event types › Participation in or organisation af a conference
ID: 126716418