Department of Molecular Biology and Genetics

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Poul Nissen

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  1. 2022
  2. Published

    Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders. / Dieudonné, Thibaud; Herrera, Sara Abad; Laursen, Michelle Juknaviciute et al.

    In: eLife, Vol. 11, e75272, 04.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  3. Published

    Structural investigations of full-length insulin receptor dynamics and signalling. / Nielsen, Jeppe; Brandt, Jakob; Boesen, Thomas et al.

    In: Journal of Molecular Biology, Vol. 434, No. 5, 167458, 03.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  4. 2021
  5. Published

    Insights into the mechanism of high lipid–detergent crystallization of membrane proteins. / Trampari, Sofia; Neumann, Caroline Marie Teresa; Hjorth-Jensen, Samuel John et al.

    In: Journal of Applied Crystallography, Vol. 54, No. Part 6, 12.2021, p. 1775-1783.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  6. Published

    Structure and Function of Na,K-ATPase-The Sodium-Potassium Pump. / Fedosova, Natalya; Habeck, Michael; Nissen, Poul.

    In: Comprehensive Physiology, Vol. 12, 12.2021, p. 2659-2679.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Commissioned › peer-review

  7. Published

    Mind the gap: molecular architecture of the axon initial segment – from fold prediction to a mechanistic model of function? / Quistgaard, Esben Meldgaard Høgh; Nissen, Josephine Dannersø; Hansen, Sean et al.

    In: Journal of Molecular Biology, Vol. 433, No. 20, 167176, 10.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  8. Published

    Structural Basis of Substrate-Independent Phosphorylation in a P4-ATPase Lipid Flippase. / Timcenko, Milena; Dieudonné, Thibaud; Montigny, Cédric et al.

    In: Journal of Molecular Biology, Vol. 433, No. 16, 167062, 08.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  9. Published

    The Crystal Structure of the Ca2+-ATPase 1 from Listeria monocytogenes reveals a Pump Primed for Dephosphorylation. / Hansen, Sara Basse; Dyla, Mateusz; Neumann, Caroline et al.

    In: Journal of Molecular Biology, Vol. 433, No. 16, 167015, 08.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  10. Published

    Membrane transport | Structure of P-Type adenosine triphosphatases. / Dach, I.; Nissen, P.

    Encyclopedia of Biological Chemistry: Third Edition. Vol. 2 Elsevier, 2021. p. 1014-1020.

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review

  11. Published

    Transport unplugged: KCCs are regulated through an N-terminal plug of the ion pathway. / Kock Flygaard, Rasmus; Neumann, Caroline; Anthony Lyons, Joseph et al.

    In: EMBO Journal, Vol. 40, No. 14, e108371, 07.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate/letter to the editor › Research › peer-review

  12. Published

    Structural insights into the inhibition of glycine reuptake. / Shahsavar, Azadeh; Stohler, Peter; Bourenkov, Gleb et al.

    In: Nature, Vol. 591, 03.2021, p. 677-681.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  13. Published

    The XBI BioLab for life science experiments at the European XFEL. / Han, Huijong; Round, Ekaterina; Schubert, Robin et al.

    In: Journal of Applied Crystallography, Vol. 54, No. Part 1, 02.2021, p. 7-21.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  14. Published

    A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition. / Focht, Dorota; Neumann, Caroline; Lyons, Joseph et al.

    In: EMBO Journal, Vol. 40, No. 1, e105164, 01.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  15. Published

    From Plant to Patient : Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development. / Christensen, Søren Brøgger; Simonsen, Henrik Toft; Engedal, Nikolai et al.

    Progress in the Chemistry of Organic Natural Products . ed. / A.D. Kinghorn; H. Falk; S. Gibbons; Y. Asakawa; J.K. Liu; V.M. Dirsch. Vol. 115 Cham : Springer, 2021. p. 59-114.

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review

  16. 2020
  17. Published

    The SERCA residue Glu340 mediates interdomain communication that guides Ca2+transport. / Geurts, Maxwell M.G.; Clausen, Johannes D.; Arnou, Bertrand et al.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 49, 12.2020, p. 31114-31122.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  18. Published

    Comparative analysis of alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism ATP1A3 mutations reveals functional deficits, which do not correlate with disease severity. / Lazarov, Elinor; Hillebrand, Merle; Schröder, Simone et al.

    In: Neurobiology of Disease, Vol. 143, 105012, 09.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  19. Published

    P4-ATPases : how an old dog learnt new tricks — structure and mechanism of lipid flippases. / Lyons, Joseph A.; Timcenko, Milena; Dieudonné, Thibaud et al.

    In: Current Opinion in Structural Biology, Vol. 63, 08.2020, p. 65-73.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  20. Published

    Structure and Mechanism of P-Type ATPase Ion Pumps. / Dyla, Mateusz; Kjærgaard, Magnus; Poulsen, Hanne et al.

    In: Annual Review of Biochemistry, Vol. 89, 06.2020, p. 583-603.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  21. Published

    Tracking Ca2+ ATPase intermediates in real time by x-ray solution scattering. / Ravishankar, Harsha; Pedersen, Martin Nors; Eklund, Mattias et al.

    In: Science Advances, Vol. 6, No. 12, eaaz0981, 03.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  22. Published

    X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release. / Gotfryd, Kamil; Boesen, Thomas; Mortensen, Jonas S. et al.

    In: Nature Communications, Vol. 11, No. 1, 1005, 21.02.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  23. Published

    Prospects for membrane protein crystals in NMX. / Hjorth-Jensen, Samuel John; Oksanen, Esko; Nissen, Poul et al.

    Neutron Crystallography in Structural Biology. ed. / Peter C.E. Moody. Elsevier, 2020. p. 47-68 (Methods in Enzymology, Vol. 634).

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review

  24. 2019
  25. Published

    Structural dynamics of P-type ATPase ion pumps. / Dyla, Mateusz; Basse Hansen, Sara; Nissen, Poul et al.

    In: Biochemical Society Transactions, Vol. 47, No. 5, 31.10.2019, p. 1247-1257.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  26. Published

    Allosteric modulation of the sarcoplasmic reticulum Ca2+ ATPase by thapsigargin via decoupling of functional motions. / Saleh, Noureldin; Wang, Yong; Nissen, Pout et al.

    In: Physical Chemistry Chemical Physics, Vol. 21, No. 39, 21.10.2019, p. 21991-21995.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  27. Published

    Structure and autoregulation of a P4-ATPase lipid flippase. / Timcenko, Milena; Lyons, Joseph A.; Januliene, Dovile et al.

    In: Nature, Vol. 571, No. 7765, 07.2019, p. 366-370.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  28. Published

    Structures of the heart specific SERCA2a Ca 2+ -ATPase. / Sitsel, Aljona; De Raeymaecker, Joren; Drachmann, Nikolaj Düring et al.

    In: EMBO Journal, Vol. 38, No. 5, e100020, 03.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  29. Published

    Thomas A. Steitz (1940-2018). / Nissen, Poul.

    In: Acta crystallographica Section D: Structural biology , Vol. 75, 03.2019, p. 354-356.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate/letter to the editor › Research › peer-review

  30. Published

    Namdinator - Automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps. / Kidmose, Rune Thomas; Juhl, Jonathan; Nissen, Poul et al.

    In: IUCrJ, Vol. 6, No. 4, 2019, p. 526-531.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  31. 2018
  32. Published

    Membrane-protein crystals for neutron diffraction. / Sørensen, Thomas Lykke Møller; Hjorth-Jensen, Samuel John; Oksanen, Esko et al.

    In: Acta crystallographica Section D: Structural biology , Vol. 74, No. Pt 12, 01.12.2018, p. 1208-1218.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  33. Published

    Nonlinear relationship between ER Ca2+ depletion versus induction of the unfolded protein response, autophagy inhibition, and cell death. / Szalai, Paula; Parys, Jan B.; Bultynck, Geert et al.

    In: Cell Calcium, Vol. 76, 01.12.2018, p. 48-61.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  34. Published

    Lipid flippases : towards structure, function and a better understanding. / Christiansen, Line Marie; Ulstrup, Jakob; Laban, Milena et al.

    2018. Poster session presented at CoLuAa 2018, Denmark.

    Research output: Contribution to conference › Poster › Research

  35. Published

    Dimethyl fumarate is an allosteric covalent inhibitor of the p90 ribosomal S6 kinases. / Andersen, Jacob Lauwring; Gesser, Borbala; Funder, Erik Daa et al.

    In: Nature Communications, Vol. 9, No. 1, 4344, 19.10.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  36. Published

    Interactions of a Bacterial Cu(I)-ATPase with a Complex Lipid Environment. / Autzen, Henriette E.; Koldsø, Heidi; Stansfeld, Phillip J. et al.

    In: Biochemistry, Vol. 57, No. 28, 17.07.2018, p. 4063-4073.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  37. Published

    Jens Christian Skou (1918–2018). / Nissen, Poul.

    In: Science, Vol. 361, No. 6398, 13.07.2018, p. 133.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Communication

  38. Published

    iNEXT : a European facility network to stimulate translational structural biology. / iNEXT Consortium.

    In: FEBS Letters, Vol. 592, No. 12, 06.2018, p. 1909-1917.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  39. Published

    Central and peripheral nervous system progenitors derived from human pluripotent stem cells reveal a unique temporal and cell-type specific expression of PMCAs. / Chen, Muwan; Laursen, Sofie H.; Habekost, Mette et al.

    In: Frontiers in Cell and Developmental Biology, Vol. 6, 5, 06.02.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  40. Published

    Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering. / Midtgaard, Søren Roi; Darwish, Tamim A.; Pedersen, Martin Cramer et al.

    In: FEBS Journal, Vol. 285, No. 2, 01.2018, p. 357-371.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  41. 2017
  42. Published

    Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response. / Sehgal, Pankaj; Szalai, Paula; Olesen, Claus et al.

    In: Journal of Biological Chemistry, Vol. 292, 12.2017, p. 19656-19673.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  43. Published

    Dynamics of P-type ATPase transport cycle revealed by single-molecule FRET. / Dyla, Mateusz; Terry, Daniel; Kjærgaard, Magnus et al.

    In: Nature, Vol. 551, No. 7680, 16.11.2017, p. 346-351.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  44. Published

    Towards the structure of yeast and mammalian P4-ATPases : Poster at the 15th International Conference on Na,K-ATPase and Related Transport ATPases, Otsu, Japan, 2017. / Lyons, Joseph; Laban, Milena; Mikkelsen, Stine et al.

    2017.

    Research output: Contribution to conference › Poster › Research

  45. Published

    Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease. / Skjørringe, Tina; Pedersen, Per Amstrup; Thorborg, Sidsel Salling et al.

    In: Scientific Reports, Vol. 7, No. 1, 757, 07.04.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  46. Published

    Brief encounters of cytochrome c. / Lyons, Joseph A; Nissen, Poul.

    In: E M B O Journal, Vol. 36, No. 3, 01.02.2017, p. 250-251.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research

  47. Published

    A High and Phosphatidylinositol-4-phosphate (PI4P)-dependent ATPase Activity for the Drs2p/Cdc50p Flippase after Removal of its N- and C-terminal Extensions. / Azouaoui, Hassina; Montigny, Cedric; Dieudonné, Thibaud et al.

    In: Journal of Biological Chemistry, Vol. 292, 2017, p. 7954-7970.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  48. Published

    Improved Model of Proton Pump Crystal Structure Obtained by Interactive Molecular Dynamics Flexible Fitting Expands the Mechanistic Model for Proton Translocation in P-Type ATPases. / Focht, Dorota; Croll, Tristan Ian; Pedersen, Bjorn P et al.

    In: Frontiers in Physiology, Vol. 8, 202, 2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  49. Published

    Saposin-Lipoprotein Scaffolds for Structure Determination of Membrane Transporters. / Lyons, Joseph A.; Bøggild, Andreas; Nissen, Poul et al.

    Methods in Enzymology: A Structure-Function Toolbox for Membrane Transporter and Channels. ed. / Christine Ziegler. Vol. 594 Academic Press, 2017. p. 85-99 (Methods in Enzymology, Vol. 594).

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review

  50. Published

    The Role of TM5 in Na2 Release and the Conformational Transition of Neurotransmitter:Sodium Symporters toward the Inward-Open State. / Stolzenberg, Sebastian; Li, Zheng; Quick, Matthias et al.

    In: Journal of Biological Chemistry, Vol. 292, 2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  51. 2016
  52. Published

    The molecular mechanism for overcoming the ratelimiting step in monoamine neurotransmitter transport. / Said, Saida; Malinauskaite, Lina; Grouleff, Julie et al.

    2016. Poster session presented at Årsmøde for Dansk Selskab for Farmakologi, Toksikologi og Medicinalkemi, Sandbjerg, Denmark.

    Research output: Contribution to conference › Poster › Research

  53. Published

    The molecular mechanism for overcoming the rate-limiting step in monoamine neurotransmitter transport. / Sinning, Steffen; Said, Saida; Malinauskaite, Lina et al.

    2016. Poster session presented at 9th SFB35 Symposium, Wien, Austria.

    Research output: Contribution to conference › Poster › Research

  54. Published

    The molecular mechanism for overcoming the rate-limiting step in monoamine neurotransmitter transport. / Sinning, Steffen; Said, Saida; Malinauskaite, Lina et al.

    2016. Poster session presented at Gordon Research Conferenc, Barga, Italy.

    Research output: Contribution to conference › Poster › Research

  55. Published

    Expression strategies for structural studies of eukaryotic membrane proteins. / Lyons, Joseph A; Shahsavar, Azadeh; Paulsen, Peter Aasted et al.

    In: Current Opinion in Structural Biology, Vol. 38, 27.06.2016, p. 137-144.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  56. Published

    Crystal Structure of the Vanadate-Inhibited Ca2+-ATPase. / Clausen, Johannes D.; Bublitz, Maike; Arnou, Bertrand Jean-Paul et al.

    In: Structure, Vol. 24, No. 4, 05.04.2016, p. 617-623.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  57. Published

    Erratum : Reappraising the effects of artemisinin on the ATPase activity of PfATP6 and SERCA1a E255L expressed in Xenopus laevis oocytes (Nature Structural and Molecular Biology (2016) 23 (1-2)). / David-Bosne, Stéphanie; Clausen, Michael Voldsgaard; Poulsen, Hanne et al.

    In: Nature Structural and Molecular Biology, Vol. 23, No. 4, 05.04.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate/letter to the editor › Research › peer-review

  58. Published

    Isolation, crystallization and crystal structure determination of bovine kidney Na+,K+-ATPase. / Lindholt, Jonas; Mattle, Daniel; Fedosova, Natalya et al.

    In: Acta Crystallographica Section F: Structural Biology Communications, Vol. 72, No. Pt. 4, 01.04.2016, p. 282-287.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  59. Published

    Initiating heavy-atom-based phasing by multi-dimensional molecular replacement. / Pedersen, Bjørn Panyella; Gourdon, Pontus; Liu, Xiangyu et al.

    In: Acta crystallographica Section D: Structural biology , Vol. 72, No. Pt 3, 01.03.2016, p. 440-445.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  60. Published

    Crystal Structure of an Ammonia-Permeable Aquaporin. / Kirscht, Andreas; Kaptan, Shreyas S; Bienert, Gerd Patrick et al.

    In: PLoS Biology, Vol. 14, No. 3, 03.2016, p. e1002411.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  61. Published

    Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model. / Bøttger, Pernille; Pedersen, Simon Glerup; Gesslein, Bodil et al.

    In: Scientific Reports, Vol. 6, No. 22047, 25.02.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  62. Published

    Reappraising the effects of artemisinin on the ATPase activity of PfATP6 and SERCA1a E255L expressed in Xenopus laevis oocytes. / David-Bosne, Stéphanie; Voldsgaard Clausen, Michael; Poulsen, Hanne et al.

    In: Nature Structural and Molecular Biology, Vol. 23, No. 1, 06.01.2016, p. 1-2.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  63. Published

    A Conserved Leucine Occupies the Empty Substrate Site of LeuT in the Na+-free Return State. / Malinauskaite, Lina; Said, Saida; Sahin, Caglanur et al.

    In: Nature Communications, Vol. 7, 11673, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  64. Published

    An Introduction to P-type ATPase Research. / Nissen, Poul.

    P-Type ATPases : Methods and Protocols. ed. / Maike Bublitz. Vol. 1377 Springer, 2016. p. 1-2 (Methods in molecular biology (Clifton, N.J.)).

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research

  65. Published

    Cognitive deficits caused by a disease-mutation in the α3 Na(+)/K(+)-ATPase isoform. / Holm, Thomas Hellesøe; Isaksen, Toke Jost; Pedersen, Simon Glerup et al.

    In: Scientific Reports, Vol. 6, No. 31972, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  66. Published

    Engineering a prototypic P-type ATPase Listeria Monocytogenes Ca(2+)-ATPase 1 for single-molecule FRET studies. / Dyla, Mateusz; Andersen, Jacob; Kjaergaard, Magnus et al.

    In: Bioconjugate Chemistry, Vol. 27, No. 9, 2016, p. 2176-2187.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  67. Published

    Misbrug af naturvidenskab i demokratidebatten: Den "kolde vinter-teori" er videnskabeligt fupmageri. / Füchtbauer, Ernst-Martin; Kjærgaard, Peter C.; Nissen, Poul et al.

    In: Jyllands-Posten, Vol. 29.11. 2016, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Contribution to newspaper - Comment/debate › Communication

  68. Published

    On the molecular mechanism of flippase- and scramblase-mediated phospholipid transport. / Montigny, Cédric; Lyons, Joseph; Champeil, Philippe et al.

    In: B B A - Molecular and Cell Biology of Lipids, Vol. 1861, No. 8, Part B, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  69. Published

    Reconstitution of Na,K-ATPase in Nanodiscs. / Gregersen, Jonas Lindholt; Fedosova, Natalya; Nissen, Poul et al.

    In: Methods in Molecular Biology, Vol. 1377, 2016, p. 403-409.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  70. Published

    The α4 isoform of the Na+ ,K+ -ATPase is tuned for changing extracellular environments. / Voldsgaard Clausen, Michael; Nissen, Poul; Poulsen, Hanne.

    In: The F E B S Journal (Online), Vol. 283, No. 2, 2016, p. 282-293.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  71. Published

    Tuning of the Na,K-ATPase by the beta subunit. / Hilbers, Florian; Kopec, Wojciech; Isaksen, Toke Jost et al.

    In: Scientific Reports, Vol. 6, No. 20442, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  72. 2015
  73. Published

    Regulation of the Ca(2+)-ATPase by cholesterol : A specific or non-specific effect? / Autzen, Henriette Elisabeth; Siuda, Iwona; Sonntag, Yonathan et al.

    In: Molecular Membrane Biology, Vol. 32, No. 3, 11.08.2015, p. 75-87.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  74. Published

    Structural studies of P-type ATPase-ligand complexes using an X-ray free-electron laser. / Bublitz, Maike; Nass, Karol; Drachmann, Nikolaj D et al.

    In: IUCrJ, Vol. 2, No. Pt 4, 01.07.2015, p. 409-420.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  75. Published

    Structure and function of Cu(I)- and Zn(II)-ATPases. / Sitsel, Oleg; Grønberg, Christina; Autzen, Henriette et al.

    In: Biochemistry, Vol. 54, No. 37, 01.07.2015, p. 5673-5683.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  76. Published

    Discovery of Tricyclic Clerodane Diterpenes as Sarco/Endoplasmic Reticulum Ca2+-ATPase Inhibitors and Structure-Activity Relationships. / De Ford, Christian; Calderón, Carlos; Sehgal, Pankaj et al.

    In: Journal of Natural Products, Vol. 78, No. 6, 26.06.2015, p. 1262-1270.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  77. Published

    Against the odds? De novo structure determination of a pilin with two cysteine residues by sulfur SAD. / Gorgel, Manuela; Bøggild, Andreas; Ulstrup, Jakob et al.

    In: Acta crystallographica Section D: Structural biology , Vol. 71, No. 5, 05.2015, p. 1095-1101.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  78. Published

    Targeting thapsigargin towards tumors. / Doan, Nhu Thi Quynh; Paulsen, Eleonora Sandholdt; Sehgal, Pankaj et al.

    In: Steroids, Vol. 97, 05.2015, p. 2-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  79. Published

    Indications of radiation damage in ferredoxin microcrystals using high-intensity X-FEL beams. / Nass, Karol; Foucar, Lutz; Barends, Thomas R M et al.

    In: Journal of Synchrotron Radiation, Vol. 22, No. 2, 03.2015, p. 225-238.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  80. Published

    Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complex. / Laursen, Mette; Gregersen, Jonas Lindholt; Yatime, Laure et al.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 112, No. 6, 10.02.2015, p. 1755-1760.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  81. Published

    Erratum : Hydrogen bond rotations as a uniform structural tool for analyzing protein architecture. / Penner, Robert C.; Andersen, Ebbe S.; Jensen, Jens L. et al.

    In: Nature Communications, Vol. 6, 6209, 03.02.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate/letter to the editor › Research › peer-review

  82. Published

    A sulfur-based transport pathway in Cu+-ATPases. / Mattle, Daniel; Zhang, Limei; Sitsel, Oleg et al.

    In: E M B O Reports, 2015, p. 728-740.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  83. Published

    Digesting New Elements in Peptide Transport. / Lyons, Joseph A; Nissen, Poul.

    In: Structure, Vol. 23, No. 10, 2015, p. 1779-80.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  84. Published

    Discovery of Tricyclic Clerodane Diterpenes as Sarco/Endoplasmic Reticulum Ca(2+)-ATPase Inhibitors and Structure-Activity Relationships. / de Ford , Christian ; Calderon, Carlos; Sehgal, Pankaj et al.

    In: Journal of Natural Products, Vol. 78 (6), 2015, p. 1262–1270.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  85. Published

    High-resolution structure of a type IV pilin from the metal-reducing bacterium Shewanella oneidensis. / Gorgel, Manuela; Ulstrup, Jakob; Bøggild, Andreas et al.

    In: BMC Biochemistry and Structural Biology, Vol. 15, No. 4, 2015, p. 1-17.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  86. Published

    Membrane proteins - do we catch up with the breathless pace of soluble protein structural biology? / Pedersen, Bjørn Panyella; Nissen, Poul.

    In: B B A - Molecular and Cell Biology of Lipids, Vol. 1850, No. 3, 2015, p. 447-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Communication

  87. 2014
  88. Published

    Hydrogen bond rotations as a uniform structural tool for analyzing protein architecture. / Penner, Robert; Andersen, Ebbe Sloth; Jensen, Jens Ledet et al.

    In: Nature Communications, Vol. 5, 5803, 17.12.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  89. Published

    S-Palmitoylation and S-Oleoylation of Rabbit and Pig Sarcolipin. / Montigny, Cédric; Decottignies, Paulette; le Maréchal, Pierre et al.

    In: Journal of Biological Chemistry, Vol. 289, 05.12.2014, p. 33850-33861.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  90. Published

    Inhibition of Ubiquitin Proteasome System Rescues the Defective Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA1) Protein Causing Chianina Cattle Pseudomyotonia. / Bianchini, Elisa; Testoni, Stefania; Gentile, Arcangelo et al.

    In: Journal of Biological Chemistry, Vol. 289, No. 48, 28.11.2014, p. 33073-33082.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  91. Published

    A mechanism for intracellular release of Na(+) by neurotransmitter/sodium symporters. / Malinauskaite, Lina; Quick, Matthias; Reinhard, Linda et al.

    In: Nature Structural and Molecular Biology, Vol. 21, No. 11, 11.2014, p. 1006-1012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  92. Published

    Structure and mechanism of Zn2+-transporting P-type ATPases. / Wang, Kaituo; Sitsel, Oleg; Meloni, Gabriele et al.

    In: Nature, Vol. 514, No. 7523, 23.10.2014, p. 518-522.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  93. Published

    Brian Clark has died - marking the end of an era : Professor Brian Frederic Carl Clark, founder of Structural Biology Research at Aarhus University, died on Monday, October 6, 2014. Aged 78 years. / Nissen, Poul; Heilesen, Lisbeth.

    In: IUBMB Life, Vol. 66, No. 10, 10.2014, p. 655-656.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Communication

  94. Published

    The flexibility of the conserved Leu99 is pivotal for overcoming the rate-limiting conformational transition of the human serotonin transporter in serotonin transport. / Said, Saida; Bjerregaard, Henriette; Severinsen, Kasper et al.

    2014. Poster session presented at Transmembrane Transporters in Health and Disease, Wien, Austria.

    Research output: Contribution to conference › Poster › Research

  95. Published

    Crystals of Na(+)/K(+)-ATPase with bound cisplatin. / Huliciak, Miroslav; Reinhard, Linda; Laursen, Mette et al.

    In: Biochemical Pharmacology, Vol. 92, No. 3, 06.09.2014, p. 494-498.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  96. Published

    Comparing crystal structures of Ca2+-ATPase in the presence of different lipids. / Drachmann, Nikolaj D; Olesen, Claus; Møller, Jesper V et al.

    In: F E B S Journal, Vol. 281, No. 18, 09.2014, p. 4249-4262.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  97. Published

    Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin. / Quistgaard, Esben M; Grøftehauge, Morten K; Madsen, Peder et al.

    In: Protein Science, Vol. 23, No. 9, 09.2014, p. 1291-1300.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  98. Published

    How do we show molecules and how they move? / Nissen, Poul.

    In: Biozoom, Vol. 3, 07.2014, p. 20-21.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Communication

  99. Published

    Methods and tools for identification of rsk/msk kinase inhibitors. / Andersen, Jacob Lauwring (Inventor); Nissen, Poul (Inventor); Iversen, Lars (Inventor) et al.

    Patent No.: WO2014048442 (A1). Apr 03, 2014.

    Research output: Patent

  100. Published

    Initiating Heavy-atom Based Phasing by Multi-Dimensional Molecular Replacement. / Pedersen, Bjørn Panyella; Gourdon, Pontus; Liu, Xiangyu et al.

    In: arXiv, Vol. 1403.7484, 28.03.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research

  101. Published

    Transport Pathway in Cu+ P-Type ATPases. / Andersson, Magnus; Mattle, Daniel; Sitsel, Oleg et al.

    In: Biophysical Journal, Vol. 106, No. 2, 28.01.2014, p. 427A-427A.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research

  102. Published

    Large Scale Identification and Categorization of Protein Sequences Using Structured Logistic Regression. / Pedersen, Bjørn Panella; Ifrim, Georgiana; Liboriussen, Poul et al.

    In: P L o S One, Vol. 9, No. 1, e85139, 20.01.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  103. Published

    A high-yield co-expression system for the purification of an intact drs2p-cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate. / Azouaoui, Hassina; Montigny, Cédric; Ash, Miriam-Rose et al.

    In: PLOS ONE, Vol. 9, No. 11, e112176, 2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  104. Published

    Copper-transporting P-type ATPases use a unique ion-release pathway. / Andersson, Magnus; Mattle, Daniel; Sitsel, Oleg et al.

    In: Nature Structural and Molecular Biology, Vol. 21, 2014, p. 43-48.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  105. Published

    Na(+),K(+)-ATPase Isoform Selectivity for Digitalis-Like Compounds Is Determined by Two Amino Acids in the First Extracellular Loop. / Weigand, Karl ; Laursen, Mette; Swarts, Herman G.P. et al.

    In: Chemical Research in Toxicology, Vol. 27, No. 12, 2014, p. 2082-2092.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  106. 2013
  107. Published

    SERCA mutant E309Q binds two Ca ions but adopts a catalytically incompetent conformation. / Clausen, Johannes D.; Bublitz, Maike; Arnou, Bertrand et al.

    In: E M B O Journal, Vol. 32, No. 24, 11.12.2013, p. 3231-3243.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  108. Published

    Heterologous expression and purification of an active human TRPV3 ion channel. / Kol, Stefan; Braun, Christian; Thiel, Gerhard et al.

    In: F E B S Journal, Vol. 280, No. 23, 12.2013, p. 6010–6021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  109. Published

    Introduction : Ca(2+) signalling and transport in health and disease. / Tidow, Henning; Nissen, Poul.

    In: F E B S Journal, Vol. 280, No. 21, 11.2013, p. 5384-5384.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  110. Published

    Probing determinants of cyclopiazonic acid sensitivity of bacterial Ca(2+) -ATPases. / Kotsubei, Aljona; Gorgel, Manuela; Morth, Jens P et al.

    In: F E B S Journal, Vol. 280, No. 21, 11.2013, p. 5441–5449.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

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