Poul Henning Jensen

  1. 2019
  2. Published

    Reductions in COQ2 Expression Relate to Reduced ATP Levels in Multiple System Atrophy Brain. / Hsiao, Jen Hsiang T.; Purushothuman, Sivaraman; Jensen, Poul H.; Halliday, Glenda M.; Kim, Woojin Scott.

    In: Frontiers in Neuroscience, Vol. 13, 1187, 01.11.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats. / Van Den Berge, Nathalie; Ferreira, Nelson; Gram, Hjalte; Mikkelsen, Trine Werenberg; Alstrup, Aage Kristian Olsen; Casadei, Nicolas; Tsung-Pin, Pai; Riess, Olaf; Nyengaard, Jens Randel; Tamgüney, Gültekin; Jensen, Poul Henning; Borghammer, Per.

    In: Acta Neuropathologica, Vol. 138, No. 4, 10.2019, p. 535-550.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models. / Mavroeidi, Panagiota; Arvanitaki, Fedra; Karakitsou, Anastasia-Kiriaki; Vetsi, Maria; Kloukina, Ismini; Zweckstetter, Markus; Giller, Karin; Becker, Stefan; Sorrentino, Zachary A; Giasson, Benoit I; Jensen, Poul Henning; Stefanis, Leonidas; Xilouri, Maria.

    In: Acta Neuropathologica, Vol. 138, No. 3, 09.2019, p. 415-441.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Stabilization of α-synuclein oligomers using formaldehyde. / Ruesink, Harm; Reimer, Lasse; Gregersen, Emil; Moeller, Arne; Betzer, Cristine; Jensen, Poul Henning.

    In: PLOS ONE, Vol. 14, No. 10, e0216764, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    The use of co-immunoprecipitation to study conformation-specific protein interactions of oligomeric α-synuclein aggregates. / Betzer, Cristine; Kofoed, Rikke Hahn; Jensen, Poul Henning.

    Neuromethods : co-immunoprecipitation methods for brain tissue. New York : Humana Press, 2019. p. 23-36 (Neuromethods, Vol. 144).

    Research output: Contribution to book/anthology/report/proceedingBook chapterEducationpeer-review

  7. 2018
  8. Published

    Reduced Cytosolic Calcium as an Early Decisive Cellular State in Parkinson's Disease and Synucleinopathies. / Betzer, Cristine; Jensen, Poul Henning.

    In: Frontiers in Neuroscience, Vol. 12, 819, 06.11.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  9. Published

    Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation. / Andersen, Michael Aagaard; Christensen, Kenneth Vielsted; Badolo, Lassina; Smith, Garrick Paul; Jeggo, Ross; Jensen, Poul Henning; Andersen, Kathrine Just; Sotty, Florence.

    In: Neurobiology of Disease, Vol. 116, 08.2018, p. 13-27.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Plasma α-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome : A pilot study. / PARS Investigators.

    In: Neurobiology of Disease, Vol. 116, 08.2018, p. 53-59.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Commentary: Alpha-Synuclein Aggregates Cause Calcium Dysregulation by Activating Calcium Pump SERCA. / Betzer, Cristine; Jensen, Poul Henning.

    In: J. Neurology Neuromedicine, Vol. 3, No. 4, 06.07.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  12. Published

    Investigation of RNA Synthesis Using 5-Bromouridine Labelling and Immunoprecipitation. / Kofoed, Rikke H; Betzer, Cristine; Lykke-Andersen, Søren; Molska, Ewa; Jensen, Poul H.

    In: Journal of Visualized Experiments, No. 135, 03.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation. / Betzer, Cristine; Lassen, Louise Berkhoudt; Olsen, Anders; Kofoed, Rikke Hahn; Reimer, Lasse; Gregersen, Emil; Zheng, Jin; Calì, Tito; Gai, Wei-Ping; Chen, Tong; Moeller, Arne; Brini, Marisa; Fu, Yuhong; Halliday, Glenda; Brudek, Tomasz; Aznar, Susana; Pakkenberg, Bente; Andersen, Jens Peter; Jensen, Poul Henning.

    In: EMBO Reports, Vol. 19, No. 5, 01.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death. / Reimer, Lasse; Lund, Louise Buur; Betzer, Cristine; Zheng, Jin; Nielsen, Lærke Dalsgaard; Kofoed, Rikke Hahn; Lassen, Louise Berkhoudt; Bølcho, Ulrik; Paludan, Søren Riis; Fog, Karina; Jensen, Poul Henning.

    In: Neurobiology of Disease, 01.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    ELISA method to detect α-synuclein oligomers in cell and animal models. / Lassen, Louise Berkhoudt; Gregersen, Emil; Isager, Anne Kathrine; Betzer, Cristine; Kofoed, Rikke Hahn; Jensen, Poul Henning.

    In: PLOS ONE, Vol. 13, No. 4, e0196056, 26.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats. / Andersen, Michael Aagaard; Wegener, Karen Malene; Larsen, Steen; Badolo, Lassina; Smith, Garrick Paul; Jeggo, Ross; Jensen, Poul Henning; Sotty, Florence; Christensen, Kenneth Vielsted; Thougaard, Annemette.

    In: Toxicology, Vol. 395, 15.02.2018, p. 15-22.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology. / Olesen, Mads N.; Christiansen, Josefine R.; Petersen, Steen Vang; Jensen, Poul Henning; Paslawski, Wojciech; Romero-Ramos, Marina; Sanchez-Guajardo, Vanesa.

    In: Heliyon, Vol. 4, No. 1, e00513, 11.01.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    A Longitudinal Study of Total and Phosphorylated α-Synuclein with Other Biomarkers in Cerebrospinal Fluid of Alzheimer's Disease and Mild Cognitive Impairment. / Wang, Hua; Stewart, Tessandra; Toledo, Jon B; Ginghina, Carmen; Tang, Lu; Atik, Anzari; Aro, Patrick; Shaw, Leslie M; Trojanowski, John Q; Galasko, Douglas R; Edland, Steven; Jensen, Poul Henning; Shi, Min; Zhang, Jing; Alzheimer’s Disease Neuroimaging Initiative.

    In: Journal of Alzheimer's Disease, Vol. 61, No. 4, 2018, p. 1541-1553.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity. / Jan, Asad; Jansonius, Brandon; Delaidelli, Alberto; Bhanshali, Forum; An, Yi Andy; Ferreira, Nelson; Smits, Lisa M; Negri, Gian Luca; Schwamborn, Jens C; Jensen, Poul H; Mackenzie, Ian R; Taubert, Stefan; Sorensen, Poul H.

    In: Acta Neuropathologica Communications, Vol. 6, No. 1, 54, 2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Cerebrospinal fluid α-synuclein contributes to the differential diagnosis of Alzheimer's disease. / Shi, Min; Tang, Lu; Toledo, Jon B; Ginghina, Carmen; Wang, Hua; Aro, Patrick; Jensen, Poul Henning; Weintraub, Daniel; Chen-Plotkin, Alice S; Irwin, David J; Grossman, Murray; McCluskey, Leo; Elman, Lauren B; Wolk, David A; Lee, Edward B; Shaw, Leslie M; Trojanowski, John Q; Zhang, Jing.

    In: Alzheimer's & Dementia, Vol. 14, No. 8, 2018, p. 1052-1062.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting. / Walsh, Ryan R; Krismer, Florian; Galpern, Wendy R; Wenning, Gregor K; Low, Phillip A; Halliday, Glenda; Koroshetz, Walter J; Holton, Janice; Quinn, Niall P; Rascol, Olivier; Shaw, Leslie M; Eidelberg, David; Bower, Pam; Cummings, Jeffrey L; Abler, Victor; Biedenharn, Judy; Brooks, David J; Brundin, Patrik; Fernandez, Hubert; Fortier, Philip; Freeman, Roy; Gasser, Thomas; Hewitt, Art; Höglinger, Günter U; Huentelman, Matt J; Jensen, Poul Henning; Jeromin, Andreas; Kang, Un Jung; Kaufmann, Horacio; Kellerman, Lawrence; Khurana, Vikram; Klockgether, Thomas; Kim, Woojin Scott; Langer, Carol; LeWitt, Peter; Masliah, Eliezer; Meissner, Wassilios; Melki, Ronald; Ostrowitzki, Susanne; Piantadosi, Steven; Poewe, Werner; Robertson, David; Roemer, Cyndi; Schenk, Dale; Schlossmacher, Michael; Schmahmann, Jeremy D; Seppi, Klaus; Shih, Lily; Siderowf, Andrew; Wenning Gregor.

    In: Neurology, Vol. 90, No. 2, 2018, p. 74-82.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  22. 2017
  23. Published

    Polo-like kinase 2 modulates α-synuclein protein levels by regulating its mRNA production. / Kofoed, Rikke H; Zheng, Jin; Ferreira, Nelson; Lykke-Andersen, Søren; Salvi, Mauro; Betzer, Cristine; Reimer, Lasse; Jensen, Torben Heick; Fog, Karina; Jensen, Poul Henning.

    In: Neurobiology of Disease, Vol. 106, 17.10.2017, p. 49-62.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    SOLUBLE AGGREGATES OF ALPHA-SYNUCLEIN ACTIVATE SERCA CAUSING CALCIUM DYSREGULATION. / Betzer, Cristine; Lassen, Louise Berkhoudt; Möller, Arne; Olsen, Anders; Kofoed, Rikke Hahn; Zheng, Jin; Cali, Tito; Brini, Marisa; Gai, Wei-Ping; Andersen, Jens Peter; Jensen, Poul Henning.

    2017. Poster session presented at 20 years of alpha-synuclein in Parkinson's disease and related synucleinopathies, Greece.

    Research output: Contribution to conferencePosterResearch

  25. Published

    SOLUBLE AGGREGATES OF ALPHA-SYNUCLEIN ACTIVATES SERCA CAUSING CALCIUM DYSREGULATION. / Betzer, Cristine; Lassen, Louise Berkhoudt; Möller, Arne; Kofoed, Rikke Hahn; Zheng, Jin; Calì, Tito; Brini, Marisa; Gai, Wei Ping; Andersen, Jens Peter; Jensen, Poul Henning.

    2017. Poster session presented at AD/PD 2017 , Vienna, Austria.

    Research output: Contribution to conferencePosterResearch

  26. 2016
  27. Published

    The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins. / Yatime, Laure; Betzer, Cristine; Jensen, Rasmus Kjeldsen; Mortensen, Sofia; Jensen, Poul Henning; Andersen, Gregers Rom.

    In: Structure, Vol. 24, No. 12, 06.12.2016, p. 2043-2052.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease. / Matrone, Carmela; Dzamko, Nicolas; Madsen, Peder; Nyegaard, Mette; Pohlmann, Regina; Søndergaard, Rikke V; Lassen, Louise B; Andresen, Thomas L; Halliday, Glenda M; Jensen, Poul Henning; Nielsen, Morten S.

    In: PLOS ONE, Vol. 11, No. 8, 10.08.2016, p. e0160501.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    REDUCED CYTOSOLIC CALCIUM CAUSED BY SERCA ACTIVATION IS AN EARLY AND PATHOGENIC EVENT IN THE CELLULAR STRESS CAUSED BY ALPHA-SYNUCLEIN OLIGOMERS. / Betzer, Cristine; Jensen, Poul Henning.

    2016. Poster session presented at FENS 2016, København, Denmark.

    Research output: Contribution to conferencePosterResearch

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