Poul Henning Jensen

  1. 2022
  2. Published

    Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers. / Alam, Parvez; Holst, Mikkel R; Lauritsen, Line et al.

    In: Fluids and Barriers of the CNS, Vol. 19, No. 1, 30.05.2022, p. 37.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity. / Ghanem, Simona S.; Majbour, Nour K.; Vaikath, Nishant N. et al.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 119, No. 15, e2109617119, 04.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Low dose DMSO treatment induces oligomerization and accelerates aggregation of α-synuclein. / Reimer, Lasse; Haikal, Caroline; Gram, Hjalte et al.

    In: Scientific Reports, Vol. 12, 3737, 03.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Recombinant adeno-associated virus mediated gene delivery in the extracranial nervous system of adult mice by direct nerve immersion. / Richner, Mette; Gonçalves, Nádia Pereira; Jensen, Poul Henning et al.

    In: STAR Protocols, Vol. 3, No. 1, 101181, 03.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. E-pub ahead of print

    Autophagy mediates the clearance of oligodendroglial SNCA/alpha-synuclein and TPPP/p25A in multiple system atrophy models. / Mavroeidi, Panagiota; Arvanitaki, Fedra; Vetsi, Maria et al.

    In: Autophagy, 09.01.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. 2021
  8. Published

    Alpha-synuclein research : defining strategic moves in the battle against Parkinson's disease. / Oliveira, Luis M A; Gasser, Thomas; Edwards, Robert et al.

    In: npj Parkinson's Disease, Vol. 7, No. 1, 65, 12.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  9. Published

    Endoplasmic Reticulum-Based Calcium Dysfunctions in Synucleinopathies. / Kovacs, Gergo; Reimer, Lasse; Jensen, Poul Henning.

    In: Frontiers in Neurology, Vol. 12, 742625, 10.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  10. Published

    Polo-like kinase 2 inhibition reduces serine-129 phosphorylation of physiological nuclear alpha-synuclein but not of the aggregated alpha-synuclein. / Elfarrash, Sara; Jensen, Nanna Møller; Ferreira, Nelson et al.

    In: PLOS ONE, Vol. 16, No. 10, e0252635, 10.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Prolyl oligopeptidase inhibition reduces alpha-synuclein aggregation in a cellular model of multiple system atrophy. / Cui, Hengjing; Kilpeläinen, Tommi; Zouzoula, Lydia et al.

    In: Journal of Cellular and Molecular Medicine, Vol. 25, No. 20, 10.2021, p. 9634-9646.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity. / Gregersen, Emil; Betzer, Cristine; Kim, Woojin S et al.

    In: Journal of Neuroinflammation, Vol. 18, 177, 08.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Enhanced tyrosine hydroxylase activity induces oxidative stress, causes accumulation of autotoxic catecholamine metabolites, and augments amphetamine effects in vivo. / Vecchio, Laura M; Sullivan, Patricia; Dunn, Amy R et al.

    In: Journal of Neurochemistry, Vol. 158, No. 4, 08.2021, p. 960-979.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    The Prion-Like Spreading of Alpha-Synuclein in Parkinson's Disease : Update on Models and Hypotheses. / Jan, Asad; Gonçalves, Nádia Pereira; Vaegter, Christian Bjerggaard et al.

    In: International Journal of Molecular Sciences , Vol. 22, No. 15, 8338, 08.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  15. Published

    Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential. / Ferreira, Nelson; Gram, Hjalte; Sorrentino, Zachary A et al.

    In: Acta Neuropathologica, Vol. 142, 07.2021, p. 87-115.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Ageing promotes pathological alpha-synuclein propagation and autonomic dysfunction in wild-type rats. / Van Den Berge, Nathalie; Ferreira, Nelson; Mikkelsen, Trine Werenberg et al.

    In: Brain : a journal of neurology, Vol. 144, No. 6, 06.2021, p. 1853–1868.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response. / Delaidelli, Alberto; Richner, Mette; Jiang, Lixiang et al.

    In: Acta Neuropathologica Communications, Vol. 9, No. 1, 105, 06.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Organotypic hippocampal slices, an emerging tool to model synucleinopathies. / Elfarrash, Sara; Jensen, Poul Henning.

    In: Neural Regeneration Research, Vol. 16, No. 5, 05.2021, p. 999-1000.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperEditorialResearchpeer-review

  19. Published

    Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy. / Ferreira, Nelson; Richner, Mette; van der Laan, Amelia et al.

    In: Brain Communications, Vol. 3, No. 2, fcab104, 05.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Multiple Protective Roles of Nanoliposome-Incorporated Baicalein against Alpha-Synuclein Aggregates. / Aliakbari, Farhang; Mohammad-Beigi, Hossein; Abbasi, Shahsanam et al.

    In: Advanced Functional Materials, Vol. 31, No. 7, 2007765, 10.02.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    PET imaging reveals early and progressive dopaminergic deficits after intra-striatal injection of preformed alpha-synuclein fibrils in rats. / Thomsen, Majken B; Ferreira, Sara A; Schacht, Anna C et al.

    In: Neurobiology of Disease, Vol. 149, 105229, 02.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain. / Ferreira, Nelson; Gonçalves, Nádia Pereira; Jan, Asad et al.

    In: Acta Neuropathologica Communications, Vol. 9, 31, 02.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    PKR kinase directly regulates tau expression and Alzheimer's Disease-related tau phosphorylation. / Reimer, Lasse; Betzer, Cristine; Kofoed, Rikke Hahn et al.

    In: Brain Pathology, Vol. 31, No. 1, 01.2021, p. 103-119.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. 2020
  25. Published

    Glycogen synthase kinase 3 β activity is essential for Polo-like kinase 2- and Leucine-rich repeat kinase 2-mediated regulation of α-synuclein. / Kofoed, Rikke H; Betzer, Cristine; Ferreira, Nelson et al.

    In: Neurobiology of Disease, Vol. 136, 104720, 03.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4. / Juul-Madsen, Kristian; Qvist, Per; Bendtsen, Kirstine L et al.

    In: Journal of Immunology, Vol. 204, No. 5, 2020, p. 1345-1361.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. 2019
  28. Published

    Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates. / Elfarrash, Sara; Jensen, Nanna Møller; Ferreira, Nelson et al.

    In: Acta Neuropathologica Communications, Vol. 7, No. 1, 213, 19.12.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model : Findings and Implications. / Andersen, Michael Aagaard; Sotty, Florence; Jensen, Poul Henning et al.

    In: eNeuro , Vol. 6, No. 6, 07.11.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Reductions in COQ2 Expression Relate to Reduced ATP Levels in Multiple System Atrophy Brain. / Hsiao, Jen Hsiang T.; Purushothuman, Sivaraman; Jensen, Poul H. et al.

    In: Frontiers in Neuroscience, Vol. 13, 1187, 01.11.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    Gene Transfer in Rodent Nervous Tissue Following Hindlimb Intramuscular Delivery of Recombinant Adeno-Associated Virus Serotypes AAV2/6, AAV2/8, and AAV2/9. / Asad, Jan; Richner, Mette; Vægter, Christian Bjerggaard et al.

    In: Neuroscience Insights, Vol. 14, No. November-December, 11.2019, p. 1-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Correction to : Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models. / Mavroeidi, Panagiota; Arvanitaki, Fedra; Karakitsou, Anastasia-Kiriaki et al.

    In: Acta Neuropathologica, Vol. 138, No. 4, 10.2019, p. 675.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats. / Van Den Berge, Nathalie; Ferreira, Nelson; Gram, Hjalte et al.

    In: Acta Neuropathologica, Vol. 138, No. 4, 10.2019, p. 535-550.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models. / Mavroeidi, Panagiota; Arvanitaki, Fedra; Karakitsou, Anastasia-Kiriaki et al.

    In: Acta Neuropathologica, Vol. 138, No. 3, 09.2019, p. 415-441.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Stabilization of α-synuclein oligomers using formaldehyde. / Ruesink, Harm; Reimer, Lasse; Gregersen, Emil et al.

    In: PLOS ONE, Vol. 14, No. 10, e0216764, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. 2018
  37. Published

    Reduced Cytosolic Calcium as an Early Decisive Cellular State in Parkinson's Disease and Synucleinopathies. / Betzer, Cristine; Jensen, Poul Henning.

    In: Frontiers in Neuroscience, Vol. 12, 819, 06.11.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  38. Published

    Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation. / Andersen, Michael Aagaard; Christensen, Kenneth Vielsted; Badolo, Lassina et al.

    In: Neurobiology of Disease, Vol. 116, 08.2018, p. 13-27.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    Plasma α-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome : A pilot study. / PARS Investigators.

    In: Neurobiology of Disease, Vol. 116, 08.2018, p. 53-59.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    Commentary: Alpha-Synuclein Aggregates Cause Calcium Dysregulation by Activating Calcium Pump SERCA. / Betzer, Cristine; Jensen, Poul Henning.

    In: J. Neurology Neuromedicine, Vol. 3, No. 4, 06.07.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  41. Published

    Investigation of RNA Synthesis Using 5-Bromouridine Labelling and Immunoprecipitation. / Kofoed, Rikke H; Betzer, Cristine; Lykke-Andersen, Søren et al.

    In: Journal of Visualized Experiments, No. 135, 03.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation. / Betzer, Cristine; Lassen, Louise Berkhoudt; Olsen, Anders et al.

    In: EMBO Reports, Vol. 19, No. 5, e44617, 01.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. Published

    Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death. / Reimer, Lasse; Lund, Louise Buur; Betzer, Cristine et al.

    In: Neurobiology of Disease, 01.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    ELISA method to detect α-synuclein oligomers in cell and animal models. / Lassen, Louise Berkhoudt; Gregersen, Emil; Isager, Anne Kathrine et al.

    In: PLOS ONE, Vol. 13, No. 4, e0196056, 26.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats. / Andersen, Michael Aagaard; Wegener, Karen Malene; Larsen, Steen et al.

    In: Toxicology, Vol. 395, 15.02.2018, p. 15-22.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology. / Olesen, Mads N.; Christiansen, Josefine R.; Petersen, Steen Vang et al.

    In: Heliyon, Vol. 4, No. 1, e00513, 11.01.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    A Longitudinal Study of Total and Phosphorylated α-Synuclein with Other Biomarkers in Cerebrospinal Fluid of Alzheimer's Disease and Mild Cognitive Impairment. / Wang, Hua; Stewart, Tessandra; Toledo, Jon B et al.

    In: Journal of Alzheimer's Disease, Vol. 61, No. 4, 2018, p. 1541-1553.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  48. Published

    Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity. / Jan, Asad; Jansonius, Brandon; Delaidelli, Alberto et al.

    In: Acta Neuropathologica Communications, Vol. 6, No. 1, 54, 2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  49. Published

    Cerebrospinal fluid α-synuclein contributes to the differential diagnosis of Alzheimer's disease. / Shi, Min; Tang, Lu; Toledo, Jon B et al.

    In: Alzheimer's & Dementia, Vol. 14, No. 8, 2018, p. 1052-1062.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting. / Walsh, Ryan R; Krismer, Florian; Galpern, Wendy R et al.

    In: Neurology, Vol. 90, No. 2, 2018, p. 74-82.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  51. 2017
  52. Published

    Polo-like kinase 2 modulates α-synuclein protein levels by regulating its mRNA production. / Kofoed, Rikke H; Zheng, Jin; Ferreira, Nelson et al.

    In: Neurobiology of Disease, Vol. 106, 17.10.2017, p. 49-62.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    SOLUBLE AGGREGATES OF ALPHA-SYNUCLEIN ACTIVATE SERCA CAUSING CALCIUM DYSREGULATION. / Betzer, Cristine; Lassen, Louise Berkhoudt; Möller, Arne et al.

    2017. Poster session presented at 20 years of alpha-synuclein in Parkinson's disease and related synucleinopathies, Greece.

    Research output: Contribution to conferencePosterResearch

  54. Published

    SOLUBLE AGGREGATES OF ALPHA-SYNUCLEIN ACTIVATES SERCA CAUSING CALCIUM DYSREGULATION. / Betzer, Cristine; Lassen, Louise Berkhoudt; Möller, Arne et al.

    2017. Poster session presented at AD/PD 2017 , Vienna, Austria.

    Research output: Contribution to conferencePosterResearch

  55. 2016
  56. Published

    The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins. / Yatime, Laure; Betzer, Cristine; Jensen, Rasmus Kjeldsen et al.

    In: Structure, Vol. 24, No. 12, 06.12.2016, p. 2043-2052.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. Published

    Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease. / Matrone, Carmela; Dzamko, Nicolas; Madsen, Peder et al.

    In: PLOS ONE, Vol. 11, No. 8, 10.08.2016, p. e0160501.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  58. Published

    REDUCED CYTOSOLIC CALCIUM CAUSED BY SERCA ACTIVATION IS AN EARLY AND PATHOGENIC EVENT IN THE CELLULAR STRESS CAUSED BY ALPHA-SYNUCLEIN OLIGOMERS. / Betzer, Cristine; Jensen, Poul Henning.

    2016. Poster session presented at FENS 2016, København, Denmark.

    Research output: Contribution to conferencePosterResearch

  59. Published

    Protein partners of α-synuclein in Health and Disease. / Lassen, Louise Berkhoudt; Reimer, Lasse; Ferreira, Nelson et al.

    In: Brain Pathology, 03.03.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  60. 2015
  61. Published

    Reduced cytosolic calcium caused by SERCA activation is an early and pathogenic event in the cellular stress caused by alpha-synuclein oligomers. / Betzer, Cristine; Jensen, Poul Henning.

    2015. Poster session presented at THE BRAIN PRIZE MEETING 2015 – “Imaging the Living Brain”, Middelfart, Denmark.

    Research output: Contribution to conferencePosterResearch

  62. Published

    Identification of Synaptosomal Proteins Binding to Monomeric and Oligomeric α-Synuclein. / Betzer, Cristine; Movius, A James; Shi, Min et al.

    In: PLOS ONE, Vol. 10, No. 2, 02.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  63. Published

    Phosphorylated α-synuclein in Parkinson's disease : correlation depends on disease severity. / Stewart, Tessandra; Sossi, Vesna; Aasly, Jan O et al.

    In: Acta Neuropathologica Communications, Vol. 3, No. 7, 2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  64. 2014
  65. Published

    How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro. / Lorenzen, Nikolai; Nielsen, Søren B.; Yoshimura, Yuichi et al.

    In: Journal of Biological Chemistry, Vol. 289, No. 31, 01.08.2014, p. 21299-21310.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  66. Published

    Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo. / Rockenstein, Edward; Nuber, Silke; Overk, Cassia R et al.

    In: Brain, Vol. 137, No. Pt 5, 05.2014, p. 1496-513.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  67. Published

    Prodegenerative IκBα expression in oligodendroglial α-synuclein models of multiple system atrophy. / Kragh, Christine L; Gysbers, Amanda M; Rockenstein, Edward et al.

    In: Neurobiology of Disease, Vol. 63, 01.03.2014, p. 171-183.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  68. Published

    Alpha synuclein in Parkinson's disease. / Kragh, Christine Lund; Romero-Ramos, Marina; Halliday, Glenda M et al.

    Handbook of Neurotoxicity. ed. / Richard M. Kostrzewa. New York : Springer Science+Business Media, 2014. p. 691-726.

    Research output: Contribution to book/anthology/report/proceedingReviewResearch

  69. Published

    DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson's disease. / Zondler, L; Miller-Fleming, L; Repici, M et al.

    In: Cell Death & Disease, Vol. 5, 2014, p. e1350.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  70. 2013
  71. Published

    Characterizing the dynamics of alpha-synuclein oligomers using hydrogen/deuterium exchange monitored by mass spectrometry. / Mysling, Simon; Betzer, Cristine; Jensen, Poul H et al.

    In: Biochemistry, 05.11.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  72. Published

    Ser129D mutant alpha-Synuclein induces earlier Motor Dysfunction while S129A results in distinctive pathology in a rat model of Parkinson's Disease. / Febbraro, Fabia; Sahin, Gurdal; Farran, Aina et al.

    In: Neurobiology of Disease, Vol. 56, 13.08.2013, p. 47-58.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  73. Published

    α-Synuclein Vaccination Prevents the Accumulation of Parkinson Disease-Like Pathologic Inclusions in Striatum in Association With Regulatory T Cell Recruitment in a Rat Model. / Sanchez-Guajardo, Vanesa; Annibali, Ambra; Jensen, Poul Henning et al.

    In: Journal of Neuropathology and Experimental Neurology, Vol. 72, No. 7, 07.2013, p. 624-45.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  74. Published

    Tubulin Polymerization Promoting Protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion. / Ejlerskov, Patrick; Rasmussen, Izabela Zorawska; Tolstrup Nielsen, Troels et al.

    In: Journal of Biological Chemistry, 29.04.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  75. Published

    A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats. / Nuber, Silke; Harmuth, Florian; Kohl, Zacharias et al.

    In: Brain, Vol. 136, No. Pt 2, 2013, p. 412-32.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  76. Published

    FAS-Dependent Cell Death in α-Synuclein Transgenic Oligodendrocyte Models of Multiple System Atrophy. / Kragh, Christine L; Fillon, Gwenaëlle; Gysbers, Amanda et al.

    In: P L o S One, Vol. 8, No. 1, 2013, p. e55243.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  77. Published

    Loss of DJ-1 protein stability and cytoprotective function by Parkinson’s disease-associated proline-158 deletion. / Rainnikko, Emmy H. ; Vesterager, Louise Buur; Shaik, Jafar Hyder Ali et al.

    In: Journal of Neurochemistry, Vol. 10.1111, 2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  78. Published

    Structural and functional characterization of two alpha-synuclein strains. / Bousset, Luc; Pieri, Laura; Ruiz-Arlandis, Gemma et al.

    In: Nature Communications, Vol. 4, 2013, p. 2575.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  79. 2012
  80. Accepted/In press

    Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo. / Colla, Emanuela; Jensen, Poul Henning; Pletnikowa, olga et al.

    In: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, No. 3301, 07.03.2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  81. Published

    Phosphorylated α-synuclein in Parkinson's disease. / Wang, Yu; Shi, Min; Chung, Kathryn A et al.

    In: Science Translational Medicine, Vol. 4, No. 121, 15.02.2012, p. 121ra20.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  82. Published

    Phosphorylated α-synuclein in Parkinson's disease. / Wang, Yu; Shi, Min; Chung, Kathryn et al.

    In: Science Translational Medicine, Vol. 4, No. 121, 15.02.2012, p. p. 121ra20 .

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  83. Published

    Effects of chemotherapeutics on organotypic corticostriatal slice cultures identified by a panel of fluorescent and immunohistochemical markers. / Nørregaard, Annette; Jensen, Stine Skov; Kolenda, Jesper et al.

    In: Neurotoxicity Research, Vol. 22, No. 1, 2012, p. 43-58.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  84. Published

    Multiple Roles of Heparin in the Aggregation of p25α. / Nielsen, Søren Bang; Yde, Pernille; Giehm, Lise et al.

    In: Journal of Molecular Biology, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  85. 2011
  86. Published

    P25α / TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity. / Fjorback, Anja Nawarecki; Sundbye, Sabrina; Dächsel, Justus C et al.

    In: F E B S Journal, Vol. 278, No. 3, 01.02.2011, p. 493-505.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  87. Published

    Direct MRI-guided stereotaxic viral mediated gene transfer of alpha-synuclein in the Gottingen minipig CNS. / GLUD, AN; Hedegaard, Claus; Nielsen, Mette Slot et al.

    In: Acta Neurobiologiae Experimentalis, Vol. 71, No. 4, 2011, p. 508-518.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  88. Published

    Direct MRI-guided stereotaxic viral mediated gene transfer of alphasynuclein in the Göttingen minipig CNS. / Jensen, Poul Henning.

    In: Acta Neurobiologiae Experimentalis, Vol. 71, No. 4, 2011, p. 508-518.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  89. 2010
  90. Published

    Presymptomatic intranuclear inclusion body disease in a 78-year-old female. / Mori, F.; Miki, Y.; Ogura, E. et al.

    In: Neuropathology, Vol. epub ahead of print, 27.07.2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  91. Published

    Co-expression of C-terminal truncated alpha-synuclein enhances full-length alpha-synuclein-induced pathology. / Ulusoy, Ayse; Febbraro, Fabia; Jensen, Poul H et al.

    In: European Journal of Neuroscience, Vol. 32, No. 3, 2010, p. 409-22.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  92. Published

    DJ-1 and {alpha}-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. / Hong, Z; Shi, M; Chung, KA et al.

    In: Brain, Vol. 133, 2010, p. 713-726.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  93. Published

    Direct gene transfer in the Gottingen minipig CNS using stereotaxic lentiviral microinjections. / GLUD, AN; Hedegaard, Claus; nielsen, MS et al.

    In: Acta Neurobiologiae Experimentalis, Vol. 70, No. 3, 2010, p. 308-315.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  94. Published

    Direct gene transfer in the Gottingen minipig CNS using stereotaxic lentiviral microinjections. / GLUD, AN; Hedegaard, Claus; Nielsen, Mette Slot et al.

    In: Acta Neurobiologiae Experimentalis, Vol. 70, No. 3, 2010, p. 308-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  95. Published

    Direct viral mediated gene transfer in substantia nigra of the Göttingen minipig induced by MRI-guided stereotaxic microinjections of lentiviral vectors encoding alpha synuclein controlled bý gait analysis. / Glud, Andreas Nørgaard; Hedegaard, Claus; Nielsen, Mette Slot et al.

    2010. Poster session presented at 62nd Annual Congress of the Scandinavian Neurosurgical Society.

    Research output: Contribution to conferencePosterResearch

  96. 2009
  97. Published

    An Exonic Insertion Encodes an Alanine Stretch in Porcine Synapsin I. / Hedegaard, Claus; Bendixen, Emøke; Jensen, Poul Henning et al.

    In: Biochemical Genetics, Vol. 47, No. 11-12, 2009, p. 812-816.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  98. Published

    Elevated levels of soluble α-synuclein oligomers in the dementia with Lewy bodies brains. / Paleologou, K.E.; Salem, S.A.; Al-Shami, R. et al.

    In: Brain, Vol. 132, 2009, p. 1093-1101.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  99. Published

    Novel proteins in α-synucleinopathies. / Kragh, Christine Lund; Jensen, Poul Henning.

    Focus on Structural Biology: Protein folding and misfolding: Neurodegenerative diseases. Vol. 7 Springer Science+Business Media, 2009. p. 207-224 (Focus on Structural Biology, Vol. 7).

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearch

  100. Published

     Is alpha-synuclein the culprit of the Parkinsonian neurodegeneration? / Kirik, Deniz; Gai, Wei-Ping; Jensen, Poul Henning.

    In: Experimental Neurology, Vol. 209, 2009, p. 3-4.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  101. Published

    α-synuclein aggregation and Ser129 phosphorylation dependent cell death in oligodendroglial cells. / Kragh, Christine Lund; Lund, Louise Buur; Febbraro, Fabia et al.

    In: Journal of Biological Chemistry, Vol. 284, 2009, p. 10211-10222.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  102. 2008
  103. Published

    Peroxiredoxin 6 in human brain: Molecular forms, cellular distribution and association with Alzheimer's disease pathology. / Power, J.H.T.; Asad, S.; Chataway, T.K. et al.

    In: Acta Neuropathologica, Vol. 115, 2008, p. 611-622.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  104. Published

    The expression of tubulin polymerization promoting protein TPPP/p25α is developmentally regulated in cultured rat brain oligodendrocytes and affected by proteolytic stress. / Goldbaum, O.; Jensen, Poul Henning; Richter-Landsberg, C.

    In: Glia, Vol. 56, 2008, p. 1736-1746.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  105. Published

     Identification of multiple posttranslational modifications in the porcine brain specific p25α. / Kleinnijenhuis, A.J.; Hedegaard, C.; Lundvig, Ditte Maria Simonsen et al.

    In: Journal of Neurochemistry, Vol. 1006, 2008, p. 925-933.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  106. 2007
  107. Published

    Determination of alpha-synuclein concentration in human plasma using ELISA. / Fjorback, A Winther; Varming, K; Jensen, P Henning.

    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 67, No. 4, 2007, p. 431-435.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  108. Published

    P25α relocalizes in oligodendroglia from myelin to glial cytoplasmic inclusions in multiple system atrophy. / Song, Y.J.; Lundvig, D.M.S.; Huang, Y. et al.

    In: American Journal of Pathology, Vol. 171, 2007, p. 1291-1303.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  109. 2006
  110. Published

    Association of alpha-Synuclein and Mutants with Lipid Membranes: Spin-Label ESR and Polarized IR. / Ramakrishnan, M.; Jensen, Poul Henning; Marsh, D.

    In: Biochemistry, Vol. 45, 2006, p. 3386-3395.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  111. Published

    Cellular parkin mutants are soluble under non-stress conditions. / Jensen, Lene Diness; Jensen, Tua Vinther; Kahns, Søren et al.

    In: NeuroReport, Vol. 17, 2006, p. 1205-1208.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  112. Published

    Oligodendrocytes within astrocytes ("emperipolesis") in the cerebral white matter in hepatic and hypoglycemic encephalopathy. / Nishie, M.; Mori, F.; Houzen, H. et al.

    In: Biochemistry, Vol. 26, 2006, p. 62-65.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  113. Published

    P25alpha immunoreactive but alpha-synuclein immunonegative neuronal inclusions in multiple system atrophy. / Baker, K.G.; Huang, Yue; McCann, H. et al.

    In: Acta Neuropathologica, Vol. 111, 2006, p. 193-195.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  114. Published

    P25alpha/Tubulin polymerization promoting protein expression by myelinating oligodendrocytes of the developing rat brain. / Skjørringe, T.; Lundvig, Ditte Maria Simonsen; Jensen, Poul Henning et al.

    In: Journal of Neurochemistry, Vol. 99, No. 1, 2006, p. 333-342.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  115. 2005
  116. Published

    P25a stimulate α-synuclein aggregation and is colocalized with aggregated α-synuclein in α-synucleinopathies. / Lindersson, Evo; Lundvig, Ditte Maria Simonsen; Madsen, Peder Søndergaard et al.

    In: Journal of Biological Chemistry, Vol. 280, 2005, p. 5703-5715.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  117. Published

    P25alpha is flexible but natively folded and binds tubulin with oligomeric stoichiometry. / Otzen, D.E.; Lundvig, Ditte Maria Simonsen; Wimmer, R. et al.

    In: Protein Sci., Vol. 14, 2005, p. 1396-1409.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  118. Published

    Pathogenic effects of α-synuclein aggregation. / Lundvig, Ditte Maria Simonsen; Linderson, E.; Jensen, Poul Henning.

    In: Molecular Brain Research, Vol. 134, No. 1, 2005, p. 3-16.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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