Projects per year
Personal profile
Keywords
- Cell biology
- Genetics
- Cerebral and nervous system
- Molecular medicine
- Protein synthesis
- Protein degradation
- Stress
- Transgenic mice
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Projects
- 1 Active
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CO2 as a metabolic signaling molecule
Fago, A. (PI), Palmfeldt, J. (Participant), Bundgård, A. M. (Participant) & Bross, P. (Participant)
01/04/2024 → 31/12/2027
Project: Research
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Heterozygous de novo variants in HSPD1 cause hypomyelinating leukodystrophy through impaired HSP60 oligomerisation.
Eskin-Schwartz, M., Seraidy, S., Paz, E., Molhem, M., Ranza, E., Antonarakis, S. E., Blanc, X., Herman, K., Benko, W. S., Libzon, S., Ben Sira, L., Fattal-Valevski, A., Dolgin, V., Birk, O. S., Kessel, A., Bross, P., Weiss, C., Azem, A. & Zerem, A., 31 Dec 2024, In: Journal of Medical Genetics. 62, 1, p. 15-24 10 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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HSP60 chaperone deficiency disrupts the mitochondrial matrix proteome and dysregulates cholesterol synthesis
Cömert, C., Kjær-Sørensen, K., Hansen, J., Carlsen, J., Just, J., Meaney, B. F., Østergaard, E., Luo, Y., Oxvig, C., Schmidt-Laursen, L., Palmfeldt, J., Fernandez-Guerra, P. & Bross, P., Oct 2024, In: Molecular Metabolism. 88, 102009.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
Microvessel and mitochondria changes in a mouse model of Alzheimer’s disease
Hasselholt, S., Cömert, C., Just, J., Bross, P., Nyengaard, J. R., Hansen, B. & Østergaard, L., 29 Aug 2024, In: BIO Web of Conferences. 129, 16017.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
Open Access -
Mitochondrial unfolded protein response-dependent β-catenin signaling promotes neuroendocrine prostate cancer
Woytash, J. A., Kumar, R., Chaudhary, A. K., Donnelly, C., Wojtulski, A., Bethu, M., Wang, J., Spernyak, J., Bross, P., Yadav, N., Inigo, J. R. & Chandra, D., 2024, (Accepted/In press) In: Oncogene. 161.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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A genome-wide CRISPR-Cas9 knockout screen identifies novel PARP inhibitor resistance genes in prostate cancer
Ipsen, M. B., Sørensen, E. M. G., Thomsen, E. A., Weiss, S., Haldrup, J., Dalby, A., Palmfeldt, J., Bross, P., Rasmussen, M., Fredsøe, J., Klingenberg, S., Jochumsen, M. R., Bouchelouche, K., Ulhøi, B. P., Borre, M., Mikkelsen, J. G. & Sørensen, K. D., Sept 2022, In: Oncogene. 41, 37, p. 4271-4281 11 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
19 Citations (Scopus)
Activities
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An inventory of the mitochondrial proteins affected by deficiency of the HSP60/10 chaperone complex; substrates and band waggoneers
Bross, P. (Lecturer)
14 Nov 2022Activity: Presentations, memberships, ownership and other activities › Lecture and oral contribution
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Mitochondrial Spare Respiratory Capacity in Fibroblast Cells as Predictor for Reprogramming to Induced Pluripotent Stem Cells
Bross, P. (Lecturer)
28 Sept 2017Activity: Presentations, memberships, ownership and other activities › Lecture and oral contribution
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Metabolism is the key to understanding cell function, Seminar and Workshop, 28.-29. September 2017, MMF, Science Center Skejby, Aarhus, Denmark
Bross, P. (Organizer)
28 Sept 2017 → 29 Sept 2017Activity: Participating in or organising an event types › Participation in or organisation af a conference
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Cellular models for medium-chain acyl-CoA dehydrogenase deficiency based on induced pluripotent stem cell technology
Bross, P. (Lecturer)
7 Oct 2016Activity: Presentations, memberships, ownership and other activities › Lecture and oral contribution
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The human Hsp60/Hsp10 chaperone system: its essential role for folding of mitochondrial matrix proteins and control of mitochondrial functions
Bross, P. (Lecturer)
7 Oct 2015Activity: Presentations, memberships, ownership and other activities › Lecture and oral contribution