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Peter Kappel Theil

Perspectives on Immunoglobulins in colostrum and milk

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Perspectives on Immunoglobulins in colostrum and milk. / Hurley, W L; Theil, Peter Kappel.

In: Nutrients, Vol. 3, 04.2011, p. 442-474.

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Hurley, W L ; Theil, Peter Kappel. / Perspectives on Immunoglobulins in colostrum and milk. In: Nutrients. 2011 ; Vol. 3. pp. 442-474.

Bibtex

@article{d90af10643014343b457b455a76e5639,
title = "Perspectives on Immunoglobulins in colostrum and milk",
abstract = " Immunoglobulins form an important component of the immunological activity found in milk and colostrum. They are central to the immunological link that occurs when the mother transfers passive immunity to the offspring. The mechanism of transfer varies among mammalian species. Cattle provide a readily available immune rich colostrum and milk in large quantities, making those secretions important potential sources of immune products that may benefit humans. Immune milk is a term used to describe a range of products of the bovine mammary gland that have been tested against several human diseases. The use of colostrum or milk as a source of immunoglobulins, whether intended for the neonate of the species producing the secretion or for a different species, can be viewed in the context of the types of immunoglobulins in the secretion, the mechanisms by which the immunoglobulins are secreted, and the mechanisms by which the neonate or adult consuming the milk then gains immunological benefit. The stability of immunoglobulins as they undergo processing in the milk, or undergo digestion in the intestine, is an additional consideration for evaluating the value of milk immunoglobulins. This review summarizes the fundamental knowledge of immunoglobulins found in colostrum, milk, and immune milk. ",
keywords = "immunoglobulins, milk, colostrum, bovine, human, immunity, passive transfer",
author = "Hurley, {W L} and Theil, {Peter Kappel}",
year = "2011",
month = apr,
doi = "10.3390/nu3040442",
language = "English",
volume = "3",
pages = "442--474",
journal = "Nutrients",
issn = "2072-6643",
publisher = "M D P I AG",

}

RIS

TY - JOUR

T1 - Perspectives on Immunoglobulins in colostrum and milk

AU - Hurley, W L

AU - Theil, Peter Kappel

PY - 2011/4

Y1 - 2011/4

N2 - Immunoglobulins form an important component of the immunological activity found in milk and colostrum. They are central to the immunological link that occurs when the mother transfers passive immunity to the offspring. The mechanism of transfer varies among mammalian species. Cattle provide a readily available immune rich colostrum and milk in large quantities, making those secretions important potential sources of immune products that may benefit humans. Immune milk is a term used to describe a range of products of the bovine mammary gland that have been tested against several human diseases. The use of colostrum or milk as a source of immunoglobulins, whether intended for the neonate of the species producing the secretion or for a different species, can be viewed in the context of the types of immunoglobulins in the secretion, the mechanisms by which the immunoglobulins are secreted, and the mechanisms by which the neonate or adult consuming the milk then gains immunological benefit. The stability of immunoglobulins as they undergo processing in the milk, or undergo digestion in the intestine, is an additional consideration for evaluating the value of milk immunoglobulins. This review summarizes the fundamental knowledge of immunoglobulins found in colostrum, milk, and immune milk.

AB - Immunoglobulins form an important component of the immunological activity found in milk and colostrum. They are central to the immunological link that occurs when the mother transfers passive immunity to the offspring. The mechanism of transfer varies among mammalian species. Cattle provide a readily available immune rich colostrum and milk in large quantities, making those secretions important potential sources of immune products that may benefit humans. Immune milk is a term used to describe a range of products of the bovine mammary gland that have been tested against several human diseases. The use of colostrum or milk as a source of immunoglobulins, whether intended for the neonate of the species producing the secretion or for a different species, can be viewed in the context of the types of immunoglobulins in the secretion, the mechanisms by which the immunoglobulins are secreted, and the mechanisms by which the neonate or adult consuming the milk then gains immunological benefit. The stability of immunoglobulins as they undergo processing in the milk, or undergo digestion in the intestine, is an additional consideration for evaluating the value of milk immunoglobulins. This review summarizes the fundamental knowledge of immunoglobulins found in colostrum, milk, and immune milk.

KW - immunoglobulins

KW - milk

KW - colostrum

KW - bovine

KW - human

KW - immunity

KW - passive transfer

U2 - 10.3390/nu3040442

DO - 10.3390/nu3040442

M3 - Journal article

C2 - 22254105

VL - 3

SP - 442

EP - 474

JO - Nutrients

JF - Nutrients

SN - 2072-6643

ER -