Per Kryger

A selective sweep in a microsporidian parasite Nosema-tolerant honeybee population, Apis mellifera

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A selective sweep in a microsporidian parasite Nosema-tolerant honeybee population, Apis mellifera. / Huang, Q.; Lattorff, H. M. G.; Kryger, P.; Le Conte, Y.; Moritz, R. F. A.

In: Animal Genetics, Vol. 45, No. 2, 2014, p. 267-273.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Huang, Q, Lattorff, HMG, Kryger, P, Le Conte, Y & Moritz, RFA 2014, 'A selective sweep in a microsporidian parasite Nosema-tolerant honeybee population, Apis mellifera', Animal Genetics, vol. 45, no. 2, pp. 267-273. https://doi.org/10.1111/age.12114

APA

Huang, Q., Lattorff, H. M. G., Kryger, P., Le Conte, Y., & Moritz, R. F. A. (2014). A selective sweep in a microsporidian parasite Nosema-tolerant honeybee population, Apis mellifera. Animal Genetics, 45(2), 267-273. https://doi.org/10.1111/age.12114

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MLA

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Author

Huang, Q. ; Lattorff, H. M. G. ; Kryger, P. ; Le Conte, Y. ; Moritz, R. F. A. / A selective sweep in a microsporidian parasite Nosema-tolerant honeybee population, Apis mellifera. In: Animal Genetics. 2014 ; Vol. 45, No. 2. pp. 267-273.

Bibtex

@article{ab7ef6d1e03546869c037f7814de9bc6,
title = "A selective sweep in a microsporidian parasite Nosema-tolerant honeybee population, Apis mellifera",
abstract = "Nosema is a microsporidian parasite of the honeybee, which infects the epithelial cells of the gut. In Denmark, honeybee colonies have been selectively bred for the absence of Nosema over decades, resulting in a breeding line that is tolerant toward Nosema infections. As the tolerance toward the Nosema infection is a result of artificial selection, we screened chromosome 14 for a selective sweep with microsatellite markers, where a major quantitative trait locus (QTL) had been identified to be involved in the reduction in Nosema spores in the honeybees. By comparing the genetic variability of 10 colonies of the selected honeybee strain with a population sample from 22 unselected colonies, a selective sweep was revealed within the previously identified QTL region. The genetic variability of the swept loci was not only reduced in relation to the flanking markers on chromosome 14 within the selected strain but also significantly reduced compared with the same region in the unselected honeybees. This confirmed the results of the previous QTL mapping for reduced Nosema infections. The success of the selective breeding may have driven the selective sweep found in our study. ",
keywords = "honeybee, genetic diversity, Nosema, resistance, selective breeding",
author = "Q. Huang and Lattorff, {H. M. G.} and P. Kryger and {Le Conte}, Y. and Moritz, {R. F. A.}",
year = "2014",
doi = "10.1111/age.12114",
language = "English",
volume = "45",
pages = "267--273",
journal = "Animal Genetics",
issn = "0268-9146",
publisher = "Wiley-Blackwell Publishing Ltd.",
number = "2",

}

RIS

TY - JOUR

T1 - A selective sweep in a microsporidian parasite Nosema-tolerant honeybee population, Apis mellifera

AU - Huang, Q.

AU - Lattorff, H. M. G.

AU - Kryger, P.

AU - Le Conte, Y.

AU - Moritz, R. F. A.

PY - 2014

Y1 - 2014

N2 - Nosema is a microsporidian parasite of the honeybee, which infects the epithelial cells of the gut. In Denmark, honeybee colonies have been selectively bred for the absence of Nosema over decades, resulting in a breeding line that is tolerant toward Nosema infections. As the tolerance toward the Nosema infection is a result of artificial selection, we screened chromosome 14 for a selective sweep with microsatellite markers, where a major quantitative trait locus (QTL) had been identified to be involved in the reduction in Nosema spores in the honeybees. By comparing the genetic variability of 10 colonies of the selected honeybee strain with a population sample from 22 unselected colonies, a selective sweep was revealed within the previously identified QTL region. The genetic variability of the swept loci was not only reduced in relation to the flanking markers on chromosome 14 within the selected strain but also significantly reduced compared with the same region in the unselected honeybees. This confirmed the results of the previous QTL mapping for reduced Nosema infections. The success of the selective breeding may have driven the selective sweep found in our study.

AB - Nosema is a microsporidian parasite of the honeybee, which infects the epithelial cells of the gut. In Denmark, honeybee colonies have been selectively bred for the absence of Nosema over decades, resulting in a breeding line that is tolerant toward Nosema infections. As the tolerance toward the Nosema infection is a result of artificial selection, we screened chromosome 14 for a selective sweep with microsatellite markers, where a major quantitative trait locus (QTL) had been identified to be involved in the reduction in Nosema spores in the honeybees. By comparing the genetic variability of 10 colonies of the selected honeybee strain with a population sample from 22 unselected colonies, a selective sweep was revealed within the previously identified QTL region. The genetic variability of the swept loci was not only reduced in relation to the flanking markers on chromosome 14 within the selected strain but also significantly reduced compared with the same region in the unselected honeybees. This confirmed the results of the previous QTL mapping for reduced Nosema infections. The success of the selective breeding may have driven the selective sweep found in our study.

KW - honeybee

KW - genetic diversity

KW - Nosema

KW - resistance

KW - selective breeding

U2 - 10.1111/age.12114

DO - 10.1111/age.12114

M3 - Journal article

C2 - 24320562

VL - 45

SP - 267

EP - 273

JO - Animal Genetics

JF - Animal Genetics

SN - 0268-9146

IS - 2

ER -