Per Kallestrup

Polymorphisms in the interleukin-7 receptor α gene and mortality in untreated HIV-infected individuals

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Hans Jakob Hartling, Viroimmunology Research Unit, Department of Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, Department of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  • Lise W. Thørner, Viroimmunology Research Unit, Department of Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, Department of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  • Christian Erikstrup
  • Rutendo Zinyama, Medical Research Council of Zimbabwe, Ministry of Health and Child Welfare, Department of Medical Laboratory Sciences, University of Zimbabwe, Zimbabwe, Zimbabwe
  • Per Kallestrup
  • Exnevia Gomo, Department of Medical Laboratory Sciences, University of Zimbabwe, Zimbabwe, Zimbabwe
  • Susanne D. Nielsen, Viroimmunology Research Unit, Department of Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, Denmark
  • Henrik Ullum, Department of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
Recently, polymorphisms in the gene encoding the interleukin-7 receptor α (IL7Rα) have been shown to influence the CD4 cell count in HIV-infected individuals. The objective of this study was to examine the impact of 10 single nucleotide polymorphisms (SNPs) in or in close proximity to the IL7Rα on mortality among 152 untreated HIV infected in a Zimbabwean cohort.
Original languageEnglish
JournalAIDS
Volume27
Issue10
Pages (from-to)1615-20
Number of pages6
ISSN0269-9370
DOIs
Publication statusPublished - 2013

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