Per Kallestrup

Anemia and growth retardation associated with Schistosoma haematobium infection in Mali: a possible subtle impact of a neglected tropical disease

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Anemia and growth retardation associated with Schistosoma haematobium infection in Mali : a possible subtle impact of a neglected tropical disease. / Stecher, Chalotte W; Sacko, Moussa; Madsen, Henry; Wilson, Shona; Wejse, Christian; Keita, Adama D; Landouré, Aly; Traoré, Mamadou S; Kallestrup, Per; Petersen, Eskild; Vennervald, Birgitte.

In: Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 111, No. 4, 01.04.2017, p. 144-153.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Stecher, CW, Sacko, M, Madsen, H, Wilson, S, Wejse, C, Keita, AD, Landouré, A, Traoré, MS, Kallestrup, P, Petersen, E & Vennervald, B 2017, 'Anemia and growth retardation associated with Schistosoma haematobium infection in Mali: a possible subtle impact of a neglected tropical disease', Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 111, no. 4, pp. 144-153. https://doi.org/10.1093/trstmh/trx037

APA

Stecher, C. W., Sacko, M., Madsen, H., Wilson, S., Wejse, C., Keita, A. D., ... Vennervald, B. (2017). Anemia and growth retardation associated with Schistosoma haematobium infection in Mali: a possible subtle impact of a neglected tropical disease. Transactions of the Royal Society of Tropical Medicine and Hygiene, 111(4), 144-153. https://doi.org/10.1093/trstmh/trx037

CBE

Stecher CW, Sacko M, Madsen H, Wilson S, Wejse C, Keita AD, Landouré A, Traoré MS, Kallestrup P, Petersen E, Vennervald B. 2017. Anemia and growth retardation associated with Schistosoma haematobium infection in Mali: a possible subtle impact of a neglected tropical disease. Transactions of the Royal Society of Tropical Medicine and Hygiene. 111(4):144-153. https://doi.org/10.1093/trstmh/trx037

MLA

Vancouver

Stecher CW, Sacko M, Madsen H, Wilson S, Wejse C, Keita AD et al. Anemia and growth retardation associated with Schistosoma haematobium infection in Mali: a possible subtle impact of a neglected tropical disease. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2017 Apr 1;111(4):144-153. https://doi.org/10.1093/trstmh/trx037

Author

Stecher, Chalotte W ; Sacko, Moussa ; Madsen, Henry ; Wilson, Shona ; Wejse, Christian ; Keita, Adama D ; Landouré, Aly ; Traoré, Mamadou S ; Kallestrup, Per ; Petersen, Eskild ; Vennervald, Birgitte. / Anemia and growth retardation associated with Schistosoma haematobium infection in Mali : a possible subtle impact of a neglected tropical disease. In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 2017 ; Vol. 111, No. 4. pp. 144-153.

Bibtex

@article{a78656572a294598876fd8ee5a20a1e8,
title = "Anemia and growth retardation associated with Schistosoma haematobium infection in Mali: a possible subtle impact of a neglected tropical disease",
abstract = "Background: The aim of this cross-sectional study was to investigate a possible association of Schistosoma haematobium with child growth development and describe a plausible schistosomiasis-related anemia in children and adults in a highly schistosomiasis endemic area of Mali.Methods: Urine, feces and blood samples from 399 participants of both sexes (2-40 years of age) were analyzed and supplemented by anthropometric measurements.Results: S. haematobium prevalence was 79.8{\%}, S. mansoni 13.2{\%} and Plasmodium falciparum 80.2{\%}. S. haematobium infection intensity as five categories was significantly associated with anemia; i.e., odds of having anemia in the highest and the next highest category was 3.25 (95{\%} CL 1.61-6.55; p<0.01) and 2.45 (95{\%} CL 1.28-4.70; p<0.01), respectively, of that in the three lower categories combined after adjusting for age group and gender and the interaction between the two factors. Anemia was most pronounced in the 2-5 year olds males (55.5{\%}, n=98). P. falciparum infection was not significantly associated with anemia. Stunting (body mass index [BMI] for age z-score<-2.00) was observed in 2.6{\%} (2/78) of the 2-5 years olds and in 7.7{\%} (14/182) in the 6-19 years age group. Lower BMI-z-scores (as continuous variable) were associated with anemia (p<0.05) while high intensity of S. haematobium infection was not significant when adjusting for age group and anemia. Participants with malaria infection had lower z-scores (as continuous variables) of weight and height for age. Lower height for age z-scores were also associated with anemia.Conclusions: S. haematobium infection is likely to impact on child growth and possibly also anemia in all age groups and advocates for inclusion of whole populations into future control programes.",
keywords = "Journal Article, anemia, growth, morbidity, NTD, schistosomiasis, sub-Saharan Africa",
author = "Stecher, {Chalotte W} and Moussa Sacko and Henry Madsen and Shona Wilson and Christian Wejse and Keita, {Adama D} and Aly Landour{\'e} and Traor{\'e}, {Mamadou S} and Per Kallestrup and Eskild Petersen and Birgitte Vennervald",
year = "2017",
month = "4",
day = "1",
doi = "10.1093/trstmh/trx037",
language = "English",
volume = "111",
pages = "144--153",
journal = "Transactions of the Royal Society of Tropical Medicine and Hygiene",
issn = "0035-9203",
publisher = "Oxford University Press",
number = "4",

}

RIS

TY - JOUR

T1 - Anemia and growth retardation associated with Schistosoma haematobium infection in Mali

T2 - a possible subtle impact of a neglected tropical disease

AU - Stecher, Chalotte W

AU - Sacko, Moussa

AU - Madsen, Henry

AU - Wilson, Shona

AU - Wejse, Christian

AU - Keita, Adama D

AU - Landouré, Aly

AU - Traoré, Mamadou S

AU - Kallestrup, Per

AU - Petersen, Eskild

AU - Vennervald, Birgitte

PY - 2017/4/1

Y1 - 2017/4/1

N2 - Background: The aim of this cross-sectional study was to investigate a possible association of Schistosoma haematobium with child growth development and describe a plausible schistosomiasis-related anemia in children and adults in a highly schistosomiasis endemic area of Mali.Methods: Urine, feces and blood samples from 399 participants of both sexes (2-40 years of age) were analyzed and supplemented by anthropometric measurements.Results: S. haematobium prevalence was 79.8%, S. mansoni 13.2% and Plasmodium falciparum 80.2%. S. haematobium infection intensity as five categories was significantly associated with anemia; i.e., odds of having anemia in the highest and the next highest category was 3.25 (95% CL 1.61-6.55; p<0.01) and 2.45 (95% CL 1.28-4.70; p<0.01), respectively, of that in the three lower categories combined after adjusting for age group and gender and the interaction between the two factors. Anemia was most pronounced in the 2-5 year olds males (55.5%, n=98). P. falciparum infection was not significantly associated with anemia. Stunting (body mass index [BMI] for age z-score<-2.00) was observed in 2.6% (2/78) of the 2-5 years olds and in 7.7% (14/182) in the 6-19 years age group. Lower BMI-z-scores (as continuous variable) were associated with anemia (p<0.05) while high intensity of S. haematobium infection was not significant when adjusting for age group and anemia. Participants with malaria infection had lower z-scores (as continuous variables) of weight and height for age. Lower height for age z-scores were also associated with anemia.Conclusions: S. haematobium infection is likely to impact on child growth and possibly also anemia in all age groups and advocates for inclusion of whole populations into future control programes.

AB - Background: The aim of this cross-sectional study was to investigate a possible association of Schistosoma haematobium with child growth development and describe a plausible schistosomiasis-related anemia in children and adults in a highly schistosomiasis endemic area of Mali.Methods: Urine, feces and blood samples from 399 participants of both sexes (2-40 years of age) were analyzed and supplemented by anthropometric measurements.Results: S. haematobium prevalence was 79.8%, S. mansoni 13.2% and Plasmodium falciparum 80.2%. S. haematobium infection intensity as five categories was significantly associated with anemia; i.e., odds of having anemia in the highest and the next highest category was 3.25 (95% CL 1.61-6.55; p<0.01) and 2.45 (95% CL 1.28-4.70; p<0.01), respectively, of that in the three lower categories combined after adjusting for age group and gender and the interaction between the two factors. Anemia was most pronounced in the 2-5 year olds males (55.5%, n=98). P. falciparum infection was not significantly associated with anemia. Stunting (body mass index [BMI] for age z-score<-2.00) was observed in 2.6% (2/78) of the 2-5 years olds and in 7.7% (14/182) in the 6-19 years age group. Lower BMI-z-scores (as continuous variable) were associated with anemia (p<0.05) while high intensity of S. haematobium infection was not significant when adjusting for age group and anemia. Participants with malaria infection had lower z-scores (as continuous variables) of weight and height for age. Lower height for age z-scores were also associated with anemia.Conclusions: S. haematobium infection is likely to impact on child growth and possibly also anemia in all age groups and advocates for inclusion of whole populations into future control programes.

KW - Journal Article

KW - anemia

KW - growth

KW - morbidity

KW - NTD

KW - schistosomiasis

KW - sub-Saharan Africa

U2 - 10.1093/trstmh/trx037

DO - 10.1093/trstmh/trx037

M3 - Journal article

VL - 111

SP - 144

EP - 153

JO - Transactions of the Royal Society of Tropical Medicine and Hygiene

JF - Transactions of the Royal Society of Tropical Medicine and Hygiene

SN - 0035-9203

IS - 4

ER -