Ole Bækgaard Nielsen

Chloride Channels Take Center Stage in Acute Regulation of Excitability in Skeletal Muscle: Implications for Fatigue

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

Initiation and propagation of action potentials in muscle fibers is a key element in the transmission of activating motor input from the central nervous system to their contractile apparatus, and maintenance of excitability is therefore paramount for their endurance during work. Here, we review current knowledge about the acute regulation of ClC-1 channels in active muscles and its importance for muscle excitability, function, and fatigue.

Original languageEnglish
JournalPhysiology
Volume32
Issue6
Pages (from-to)425-434
Number of pages10
ISSN1548-9213
DOIs
Publication statusPublished - Nov 2017

    Research areas

  • Journal Article, Review

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