Nicola Pavese

Professor

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Nicola Pavese

Professor

  • Department of Clinical Medicine - Nuclear Medicine and PET
Postal address:
Palle Juul-Jensens Boulevard 165
8200
Aarhus N
Denmark

Email: npavese@clin.au.dk

Curriculum Vitae

I am leading an international research programme focused on the imaging of the prodromal phase of Parkinson’s disease and other alpha-synucleinopathies. We use Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI)to characterise the pathological brain changes occurring in the early stages of these conditions. This line of research aims to identify new early targets for pharmacological treatment, sensitive and specific imaging biomarkers of these diseases to improve early detection and differential diagnosis, and biomarkers of disease progression to help development of disease-modifying agents.  Recently, we have demonstrated the presence of microglial activation, a marker of neuroinflammation, in subjects at high risk of developing synucleinopathies, suggesting that PET may be a useful marker of active subclinical disease and could  allow an early diagnosis of these conditions in patients at risk, possibly when the pathological process is still confined and disease-modifying agents, which are currently been developed, could be most beneficial. We are also collaborating with the colleagues of the Department of Biomedicine (Dr Marina Romero-Ramos and her team) to explore the link between neuroinflammation and peripheral immune system responses in patients with or at risk of developing Parkinson's disease.

I have received research grants from the Independent Research Fund Denmark, the Danish Parkinson’s Association, Parkinson’s UK, and the MSA Trust.

I have published over 200 reports including reviews, book chapters and editorials. 

I am a Fellow of the Royal College of Physicians, a Fellow of the Royal Society of Medicine, and a Fellow of the European Academy of Neurology. I am a standing member of several study groups, including the International Parkinson and Movement Disorder Society and the European Academy of Neurology.  I am also a member of Parkinson’s UK College of Experts and the Advisory Panel for The National Institute for Health Research - Research for Patient Benefit Programme (London, UK). 

I am the Section Editor for Neuroimaging for Current Neurology and Neuroscience Reports and Associate Editor for Brain Communications.