Nelson Ferreira

  1. 2021
  2. Published

    Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain. / Ferreira, Nelson; Gonçalves, Nádia Pereira; Jan, Asad; Jensen, Nanna Møller; van der Laan, Amelia; Mohseni, Simin; Vægter, Christian Bjerggaard; Jensen, Poul Henning.

    In: Acta Neuropathologica Communications, Vol. 9, No. 1, 25.02.2021, p. 31.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. 2020
  4. Published

    Glycogen synthase kinase 3 β activity is essential for Polo-like kinase 2- and Leucine-rich repeat kinase 2-mediated regulation of α-synuclein. / Kofoed, Rikke H; Betzer, Cristine; Ferreira, Nelson; Jensen, Poul Henning.

    In: Neurobiology of Disease, Vol. 136, 104720, 03.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. 2019
  6. Published

    Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates. / Elfarrash, Sara; Jensen, Nanna Møller; Ferreira, Nelson; Betzer, Cristine; Thevathasan, Jervis Vermal; Diekmann, Robin; Adel, Mohamed; Omar, Nisreen Mansour; Boraie, Mohamed Z; Gad, Sabry; Ries, Jonas; Kirik, Deniz; Nabavi, Sadegh; Jensen, Poul Henning.

    In: Acta Neuropathologica Communications, Vol. 7, No. 1, 213, 19.12.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats. / Van Den Berge, Nathalie; Ferreira, Nelson; Gram, Hjalte; Mikkelsen, Trine Werenberg; Alstrup, Aage Kristian Olsen; Casadei, Nicolas; Tsung-Pin, Pai; Riess, Olaf; Nyengaard, Jens Randel; Tamgüney, Gültekin; Jensen, Poul Henning; Borghammer, Per.

    In: Acta Neuropathologica, Vol. 138, No. 4, 10.2019, p. 535-550.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Uncovering the Neuroprotective Mechanisms of Curcumin on Transthyretin Amyloidosis. / Ferreira, Nelson; Saraiva, Maria João; Almeida, Maria Rosário.

    In: International Journal of Molecular Sciences, Vol. 20, No. 6, 1287, 03.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  9. Published

    Functional and Structural Changes of the Blood-Nerve-Barrier in Diabetic Neuropathy. / Richner, Mette; Ferreira, Nelson; Dudele, Anete; Jensen, Troels S; Vaegter, Christian B; Gonçalves, Nádia P.

    In: Frontiers in Neuroscience, Vol. 12, 1038, 01.01.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  10. 2018
  11. Published

    Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity. / Jan, Asad; Jansonius, Brandon; Delaidelli, Alberto; Bhanshali, Forum; An, Yi Andy; Ferreira, Nelson; Smits, Lisa M; Negri, Gian Luca; Schwamborn, Jens C; Jensen, Poul H; Mackenzie, Ian R; Taubert, Stefan; Sorensen, Poul H.

    In: Acta Neuropathologica Communications, Vol. 6, No. 1, 54, 2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. 2017
  13. Published

    Polo-like kinase 2 modulates α-synuclein protein levels by regulating its mRNA production. / Kofoed, Rikke H; Zheng, Jin; Ferreira, Nelson; Lykke-Andersen, Søren; Salvi, Mauro; Betzer, Cristine; Reimer, Lasse; Jensen, Torben Heick; Fog, Karina; Jensen, Poul Henning.

    In: Neurobiology of Disease, Vol. 106, 17.10.2017, p. 49-62.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. 2016
  15. Published

    Protein partners of α-synuclein in Health and Disease. / Lassen, Louise Berkhoudt; Reimer, Lasse; Ferreira, Nelson; Betzer, Cristine; Jensen, Poul Henning.

    In: Brain Pathology, 03.03.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Curcumin: A multi-target disease-modifying agent for late-stage transthyretin amyloidosis. / Ferreira, Nelson; Goncalves, Nádia Pereira; Saraiva, Maria J.; Almeida, Maria R.

    In: Scientific Reports, Vol. 6, 26623, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity. / Sant'Anna, Ricardo; Gallego, Pablo; Z. Robinson, Lei; Pereira-Henriques, Alda; Ferreira, Nelson; Pinheiro, Francisca; Esperante, Sebastian; Pallares, Irantzu; Huertas, Oscar; Almeida, Maria Rosário; Reixach, Natàlia; Insa, Raul; Velazquez-Campoy, Adrian; Reverter, David; Reig, Núria; Ventura, Salvador.

    In: Nature Communications, Vol. 7, 10787, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. 2015
  19. Published

    Transthyretin chemical chaperoning by flavonoids: Structure–activity insights towards the design of potent amyloidosis inhibitors. / Ferreira, Nelson; Pereira-Henriques, Alda; Almeida, Maria Rosário.

    In: Biochemistry and Biophysics Reports, Vol. 3, No. September 2015, 09.2015, p. 123-133.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. 2014
  21. Published

    Molecular tweezers targeting transthyretin amyloidosis. / Ferreira, Nelson; Pereira-Henriques, Alda; Attar, Aida; Klärner, Frank-Gerrit; Schrader, Thomas; Bitan, Gal; Gales, Luís; Saraiva, Maria João; Almeida, Maria Rosário.

    In: Neurotherapeutics, Vol. 11, No. 2, 04.2014, p. 450-61.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. 2013
  23. Published

    Dietary curcumin counteracts extracellular transthyretin deposition : insights on the mechanism of amyloid inhibition. / Ferreira, Nelson; Santos, Sónia A O; Domingues, Maria Rosário M; Saraiva, Maria João; Almeida, Maria Rosário.

    In: B B A - Molecular Basis of Disease, Vol. 1832, No. 1, 01.2013, p. 39-45.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. 2012
  25. Published

    Natural polyphenols as modulators of TTR amyloidogenesis : in vitro and in vivo evidences towards therapy. / Ferreira, Nelson; Saraiva, Maria João; Almeida, Maria Rosário.

    In: Amyloid: the Journal of Protein Folding Disorders, Vol. 19 Suppl 1, 06.2012, p. 39-42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Transthyretin deposition in familial amyloidotic polyneuropathy. / Saraiva, M. J.; Magalhaes, J.; Ferreira, Nelson; Almeida, M. R.

    In: Current Medicinal Chemistry, Vol. 19, No. 15, 01.05.2012, p. 2304-2311.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Epigallocatechin-3-gallate as a potential therapeutic drug for TTR-related amyloidosis: "in vivo" evidence from FAP mice models. / Ferreira, Nelson; Saraiva, Maria João; Almeida, Maria Rosário.

    In: PLOS ONE, Vol. 7, No. 1, 2012, p. e29933.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. 2011
  29. Published

    Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation. / Ferreira, Nelson; Saraiva, Maria João; Almeida, Maria Rosário.

    In: FEBS Letters, Vol. 585, No. 15, 04.08.2011, p. 2424-30.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. 2009
  31. Published

    Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicity. / Ferreira, Nelson; Cardoso, Isabel; Domingues, Maria Rosário; Vitorino, Rui; Bastos, Margarida; Bai, Guangyue; Saraiva, Maria João; Almeida, Maria Rosário.

    In: FEBS Letters, Vol. 583, No. 22, 19.11.2009, p. 3569-76.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. 2008
  33. Published

    Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of Familial Amyloidotic Polyneuropathy. / Macedo, Bárbara; Batista, Ana Rita; Ferreira, Nelson; Almeida, Maria Rosário; Saraiva, Maria João.

    In: B B A - Molecular Basis of Disease, Vol. 1782, No. 9, 01.09.2008, p. 517-522.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. 2007
  35. Published

    Comparative in vitro and ex vivo activities of selected inhibitors of transthyretin aggregation : Relevance in drug design. / Cardoso, Isabel; Almeida, Maria Rosário; Ferreira, Nelson; Arsequell, Gemma; Valencia, Gregorio; Saraiva, Maria João.

    In: Biochemical Journal, Vol. 408, No. 1, 15.11.2007, p. 131-138.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review