Research output per year
Research output per year
Personal profile
Research
Our research focuses on bioinformatic analysis of high-dimensional data to understand the interaction between the immune system and cancer. Using genomic, transcriptomic, and single-cell data, we explore tumor biology and host immune responses to develop integrated, holistic biomarkers that can predict treatment response and support improved patient care.
Profile
I lead a translational cancer bioinformatics group focused on the interplay between the immune system and cancer. Using genomic, transcriptomic, and single-cell data, we study cancer development, treatment response, and patient outcomes. Our goal is to integrate tumor and host biomarkers into holistic measures to guide precision therapy and improve clinical decision-making.
Job responsibilities
I lead a research group performing translational cancer research using bioinformatic tools. Our field of interest includes most cancer types, but particularly including lung, bladder, colon and melanoma.
Areas of expertise
- Cancer Research
- Bioinformatics
- Translational research
Fingerprint
Dive into the research topics where Nicolai Juul Birkbak is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Advancing circulating tumor DNA detection: Using whole-genome sequencing to power minimal residual disease monitoring in breast cancer
Andersen, L. & Birkbak, N. J., 20 Mar 2025, (E-pub / Early view) In: Annals of Oncology.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Editorial
-
Comprehensive genomic characterization of early-stage bladder cancer
Prip, F., Lamy, P., Lindskrog, S. V., Strandgaard, T., Nordentoft, I., Birkenkamp-Demtröder, K., Birkbak, N. J., Kristjánsdóttir, N., Kjær, A., Andreasen, T. G., Ahrenfeldt, J., Pedersen, J. S., Rasmussen, A. M., Hermann, G. G., Mogensen, K., Petersen, A. C., Hartmann, A., Grimm, M. O., Horstmann, M. & Nawroth, R. & 12 others, , Jan 2025, In: Nature Genetics. 57, 1, p. 115-125 11 p., 2301.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access2 Citations (Scopus) -
Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines
Garde, C., Pavlidis, M. A., Garces, P., Lange, E. J., Ramarathinam, S. H., Sokač, M., Pandey, K., Faridi, P., Ahrenfeldt, J., Chung, S., Friis, S., Kleine-Kohlbrecher, D., Birkbak, N. J., Kringelum, J. V., Rønø, B., Purcell, A. W. & Trolle, T., 2025, In: NPJ vaccines. 10, 1, 54.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
ImmuneLENS characterizes systemic immune dysregulation in aging and cancer
TRACERx Consortium & Genomics England Consortium, Mar 2025, In: Nature Genetics. 57, 3, p. 694-705 12 p., 305.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access2 Citations (Scopus) -
Low T cell diversity associates with poor outcome in bladder cancer: A comprehensive longitudinal analysis of the T cell receptor repertoire
Kjær, A., Kristjánsdóttir, N., Juul, R. I., Nordentoft, I., Birkenkamp-Demtröder, K., Ahrenfeldt, J., Strandgaard, T., Radif, D., Hodgson, D., Abbosh, C., Aerts, H. J. W. L., Agerbæk, M., Jensen, J. B., Birkbak, N. J. & Dyrskjøt, L., 2025, (E-pub / Early view) In: Cell Reports Medicine. 102101.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access
-
-
Al Jalila Foundation
Birkbak, N. J. (Member)
7 Jul 2023Activity: Presentations, memberships, employment, ownership and other activities › Member of evaluation panel
-
Helse Sør-Øst RHF
Birkbak, N. J. (Member)
22 Jun 2022 → …Activity: Presentations, memberships, employment, ownership and other activities › Member of evaluation panel
-
Danish National Genome Center
Birkbak, N. J. (Member)
2 Jun 2021 → …Activity: Presentations, memberships, employment, ownership and other activities › Member of committee, council or board