Morten Skovgaard Jensen

Associate professor

Curriculum Vitae

Curriculum Vitae

Morten Skovgaard Jensen

Født: 29/08/1956

Eksaminer

Matematisk naturvidenskabelig studentereksamen, Hjørring Gymnasium 1975.

Lægevidenskabelig embedseksamen. Århus Universitet, Jan. 1984.

Kliniske ansættelser

Reservelæge: Afd. for Klinisk Neurofysiologi. Aalborg Sygehus. Feb. 1984 - April 1985

Reservelæge: Afd. for Abdominal Kirurgi. Aalborg Sygehus. April 1985 - Okt. 1985.

 

Nuværende ansættelse

Lektor, Neurobiologisk Afdeling, Anatomisk Institut, Aarhus Universitete. Feb. 1997

Primære forskningsområder

Farmakologiske undersøgelse af GABA og Glutamat agonister og antagonister

Inhibitorisk og eksitatorisk synaptiske transmission i Hippocampus

In vitro modeller for epileptisk aktivitet i hippocampus

Præsynaptiske mekanisker for neurotransmitter frigivelse

Synaptisk plasticitet og hukommelses i hippocampus.

Synaptiske forandringer relateret til Alzheimers Sygdom.

Adfærds test af hukommelse i gnavere.

Regulation af hjernens gennemblødning, hypoxi og Alzheimers Sygdom

Videnskabeligt arbejde (H-factor 21)  - Se publikations liste

Tidligere ansættelser

  • Scholarstipendiat, Fysiologisk Institut, Aarhus Universitet. Jan. 1982 - Feb. 1983, Juni 1983 - Okt. 1983.
  • Kandidatstipendiat, Fysiologisk Institut, Aarhus Universitet. Okt. 1985 til Marts 1988.
  • Videnskabelig medarbejder, Fysiologisk Institut, Aarhus Universitet. April 1988 til Sept. 1989.
  • Seniorstipendiat, Fysiologisk Institut, Aarhus Universitet. Okt. 1989 - Sept. 1992.
  • Videnskabelig medarbejder, Fysiologisk Institut, Aarhus Universitet. Okt. 1992 - Feb. 1993.
  • Seniorstipendiat, Fysiologisk Institut, Aarhus Universitet. Marts. 1993 - Feb. 1994.
  • Forskningsadjunkt, Fysiologisk Institut, Aarhus Universitet. Marts. 1994 - Feb. 1995.
  • Lektorvikar, Fysiologisk Institut, Aarhus Universitet. Marts. 1995 - Jan. 1997.

Udenlandsophold

  • Max Planck Inst. fur Psychiatrie. München Vesttyskland. 1986. 3 mdr.
  • Dept. of Physiology, Hebrew University, Jerusalem. Ca. 3.5 år i perioden 1987 til 1999. Forskning i in vitro modelsystemer for epileptisk aktivitet.

Forskningsstipendier

  • Rejsestipendium fra European Training Programme (ETP) in Brain and Behaviour Research. 1988. 3 mdr.
  • Short Term Fellowship, European Molecular Biology Organization (EMBO). 1989-1990. 3 mdr.
  • Golda Meir Postdoctoral Fellowship, Lady Davis Fellowship Trust. 1990-1991. 12 mdr.

Undervisning

Medicinsk Fysiologi, Medicinske Fakultet, Aarhus Universitet 1985 til 1996.

Eksaminator i Fysiologi, 1995-1996.

Sensor i almen farmakologi,  Dansk Farmaceutisk Universitet, fra 1998.

Funktionel Neuroanatomi, Health, Aarhus Universitet fra 1997- (Kursus koordinator fra 2001)

Eksaminator i Neuroanatomi, fra 1997.

Neuroscience Bachelor, Health, Aarhus Universitet fra 2013 - (kursus koordinator)

Vejleder for 1 Post doc., 4 Ph. D. Studerende, 10 Speciale Studerende.

Kontakt information

Profile photo

Morten Skovgaard Jensen

Associate professor

  • Department of Biomedicine - Forskning og uddannelse, Syd
Postal address:
Wilhelm Meyers Allé 3
1234, 216
8000
Aarhus C
Denmark

Email: msj@biomed.au.dk

Phone: +4587167616

Publikationer

Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice

Myhre, C. L., Thygesen, C., Villadsen, B., Vollerup, J., Ilkjaer, L., Krohn, K. T., Grebing, M., Zhao, S., Khan, A. M., Dissing-Olesen, L., Jensen, M. S., Babcock, A. A. & Finsen, B., Jul 2019, In : Frontiers in Cellular Neuroscience. 13, 17 p., 308.

Disturbances in the control of capillary flow in an aged APP(swe)/PS1 Delta E9 model of Alzheimer's disease

Gutierrez-Jimenez, E., Angleys, H., Rasmussen, P. M., West, M. J., Catalini, L., Iversen, N. K., Jensen, M. S., Frische, S. & Ostergaard, L., Feb 2018, In : Neurobiology of Aging. 62, p. 82-94 13 p.

The sorting receptor SorCS3 is a stronger regulator of glutamate receptor functions compared to GABAergic mechanisms in the hippocampus

Bundgaard Christiansen, G., Andersen, K., Riis, S., Nykjær, A., Bølcho, U., Jensen, M. S. & Holm, M. M., 13 Feb 2017, In : The Hippocampus. p. 235-248 27.

Cortical spreading depolarizations in the postresuscitation period in a cardiac arrest male rat model

Hansen, F. B., Secher, N., Jensen, M. S., Østergaard, L., Tønnesen, E. K. & Granfeldt, A., 2017, In : Journal of Neuroscience Research. 95, 10, p. 2040-2050 11 p.

Neurodissektion: Dissektionsvejledning i neuroanatomi

Mikkelsen, R. & Jensen, M. S., 18 Mar 2016, 56 p.

A zinc fixative for 3D visualization of cerebral capillaries and pericytes

Nikolajsen, G. N., Jensen, M. S. & West, M. J., 15 Jan 2016, In : Journal of Neuroscience Methods. 257, p. 1-6 6 p.

Cortical Spreading Depolarizations after Cardiac Arrest in an Asphyxial Rat Model

Hansen, F. B., Secher, N., Jensen, M. S., Østergaard, L., Tønnesen, E. K. & Granfeldt, A., 7 Nov 2015.

Microcirculatory dysfunction and tissue oxygenation in critical illness

Østergaard, L., Granfeldt, A., Secher, N., Tietze, A., Iversen, N. K., Jensen, M. S., Andersen, K. K., Nagenthiraja, K., Gutiérrez-Lizardi, P., Mouridsen, K., Jespersen, S. N. & Tønnesen, E. K., 1 Nov 2015, In : Acta Anaesthesiologica Scandinavica. 59, 10, p. 1246-59 14 p.

Quantitative analysis of the capillary network of aged APPswe/PS1dE9 transgenic mice

Nikolajsen, G. N., Kotynski, K. A., Jensen, M. S. & West, M. J., Nov 2015, In : Neurobiology of Aging. 36, 11, p. 2954-62 9 p.

Long-term potentiation and the role of N-methyl-D-aspartate receptors

Volianskis, A., France, G., Jensen, M. S., Bortolotto, Z. A., Jane, D. E. & Collingridge, G. L., 24 Sep 2015, In : Gene Expression Patterns. 1621, p. 5-16 12 p.

The Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Displays Hippocampal Hyperexcitability, and Reduced Number of Interneurons, but No Presynaptic Vesicle Release Impairments

Thielsen, K. D., Moser, J. M., Schmitt-John, T., Jensen, M. S., Jensen, K. & Holm, M. M., 11 Dec 2013, In : P L o S One. 8(12), e82767, 15 p.

Hippocampal Hyperexcitability and a Reduced Number of Parvalbumin Positive Interneurons in the Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS)

Thielsen, K. D., Moser, J. M., Schmitt-John, T., Jensen, M. S., Jensen, K. & Holm, M. M., 10 Nov 2013.

The capillary dysfunction hypothesis of Alzheimer's disease

Østergaard, L., Aamand, R., Gutiérrez Jiménez, E., Ho, Y. C. L., Blicher, J., Madsen, S. M., Nagenthiraja, K., Dalby, R. B., Drasbek, K. R., Møller, A., Brændgaard, H., Mouridsen, K., Jespersen, S. N., Jensen, M. S. & West, M. J., 12 Jan 2013, In : Neurobiology of Aging. 34, 4, p. 1018-31 14 p.

Hyperexcitability and a Reduced Number of Interneurons in the Wobbler Mouse Model of ALS

Thielsen, K. D., Moser, J. M., Schmitt-John, T., Jensen, M. S., Jensen, K. & Holm, M. M., 2013.

The roles of STP and LTP in synaptic encoding

Volianskis, A., Collingridge, G. L. & Jensen, M. S., 2013, In : PeerJ. 1, p. e3

Different NMDAR subtypes mediate induction of LTP and two forms of STP at CA1 synapses in the rat hippocampus in vitro

Volianskis, A., Bannister, N., Collett, V. J., Irvine, M. W., Monaghan, D. T., Fitzjohn, S., Jensen, M. S., Jane, D. E. & Collingridge, G. L., 2012, In : The Journal of Physiology.

Cholinergic axon length reduced by 300 meters in the brain of an Alzheimer mouse model.

Nikolajsen, G., Jensen, M. S. & West, M. J., 14 Jul 2011, In : Neurobiology of Aging. 32, 11, p. 1927-1931 5 p.

Activation of nicotinic α(7) acetylcholine receptor enhances long term potentation in wild type mice but not in APP(swe)/PS1ΔE9 mice

Söderman, A., Mikkelsen, J. D., West, M. J., Christensen, D. Z. & Jensen, M. S., 10 Jan 2011, In : Neuroscience Letters. 487, 3, p. 325-9 5 p.

Episodic memory deficits are not related to altered glutamatergic synaptic transmission and plasticity in the CA1 hippocampus of the APPswe/PS1DeltaE9-deleted transgenic mice model of beta-amyloidosis

Volianskis, A., Køstner, R., Mølgaard, M., Hass, S. & Jensen, M. S., Jul 2010, In : Neurobiology of Aging. 31, 7, p. 1173-87

Cognitive deficits in the rat chronic mild stress model for depression: Relation to anhedonic-like responses

Henningsen, K., Andreasen, J. T., Bouzinova, E. V., Jayatissa, M. N., Jensen, M. S., Redrobe, J. P. & Wiborg, O., 2009, In : Behavioural Brain Research. 198, 1, p. 136-41 6 p.

Deficits in aversive but not in safe taste memory in the APPswe/PS1dE9 mice

Ramírez-Lugo, L., Jensen, M. S., Søderman, A. & West, M. J., 2009, In : Journal of Alzheimer's disease : JAD. 18, 2, p. 281-93 12 p.

The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice overexpressing human amyloid-beta1-42

Søderman, A., Thomsen, M. S., Hansen, H. H., Nielsen, E. Ø., Jensen, M. S., West, M. J. & Mikkelsen, J. D., 28 Aug 2008, In : Gene Expression Patterns. 1227, p. 240-7 8 p.

Behavioral proliferative and molecular correlations in the rat chronic mild stress model of depression

Wiborg, O., Jayatissa, M. N., Bisgaard, C., Christensen, T., Henningsen, K. & Jensen, M. S., 2008, In : European Neuropsychopharmacology. 18, S4, p. S257 1 p.

The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice oxerexpressing human amyloid-beta 1-42

Søderman, A., Thomsen, M. S., Hansen, H. H., Nielsen, E. Ø., Jensen, M. S., West, M. J. & Mikkelsen, J. D., 2008, In : Brain Research. 1227, p. 240-47 8 p.

The lack of effects of zinc and nitric oxide in initial state of pilocarpine-induced seizures

Noyan, B., Jensen, M. S. & Danscher, G., 2007, In : Seizure - European Journal of Epilepsy. 16, 5, p. 410-416

Transient and sustained types of long-term potentiation in the CA1 area of the rat hippocampus

Volianskis, A. & Jensen, M. S., 2003, In : J. Physiol.. 550-2, p. 459-492 34 p.

Developmental increase in asynchronous GABA release in cultured hippocampal neurons

Jensen, K., Jensen, M. S., Bonefeld, B. E. & Lambert, J. D., 2000, In : Neuroscience. 101, p. 581-588 8 p.

Developmental increase in asynchronous GABA release in cultured rat hippocampal neurons

Jensen, K., Jensen, M. S., Bonefeld, B. E. & Lambert, J. D. C., 2000, In : Neuroscience. 101, p. 581-588 8 p.

Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains

Suh, S. W., Jensen, K. B., Jensen, M. S., Silva, D. S., Kesslak, P. J., Danscher, G. & Frederickson, C. J., 2000, In : Brain Research. 852, p. 274-278 5 p.

Release of synaptic zinc is substantially depressed by conventional brain slice preparations

Suh, S. W., Danscher, G., Jensen, M. S., Thompson, R., Motamedi, M. & Frederickson, C. J., 2000, In : Brain Research. 879, p. 7-12 6 p.

Tetanus-induced asynchronous GABA release in cultured hippocampal neurons

Jensen, K., Lambert, J. D. C. & Jensen, M. S., 2000, In : Brain Research. 880, p. 198-201 4 p.

The effect of internal GTPγS on GABA release in cultured hippocampal neurones

Jensen, K., Lambert, J. D. C. & Jensen, M. S., 2000, In : Experimental Brain Research. 134, p. 204-211 8 p.

Zinc-enriched (ZEN) terminals in mouse olfactory bulb

Jo, S. M., Won, M. H., Cole, T. B., Jensen, M. S., Palmiter, R. D. & Danscher, G., 2000, In : Brain Research. 865, 2, p. 227-36 10 p.

Activity-dependent depression of GABAergic IPSCs in cultured hippocampal neurons

Jensen, K., Lambert, J. D. C. & Jensen, M. S., 1999, In : Journal of Neurophysiology. 82, p. 42-49 8 p.

Post-tetanic potentiation of GABAergic IPSCs in cultured hippocampal neurones

Jensen, K., Jensen, M. S. & Lambert, J. D. C., 1999, In : Journal of Physiology. 519, p. 71-84 14 p.

The role of presynaptic L-type Ca2+-channels in GABAergic synaptic transmission in cultured neurons

Jensen, K., Jensen, M. S. & Lambert, J. D. C., 1999, In : Journal of Neurophysiology. 81, p. 1225-1230 6 p.

Role of intrinsic burst firing, potassium accumulation, and electrical coupling in the elevated potassium model of hippocampal epilepsy

Jensen, M. S. & Yaari, Y., 1997, In : Journal of Neurophysiology. 77, 3, p. 1224-33 9 p.

Ionic basis of spike after-depolarization and burst generation in adult rat hippocampal CA1 pyramidal cells

Azouz, R., Jensen, M. S. & Yaari, Y., 1996, In : Journal of Physiology. 492 ( Pt 1), p. 211-23 12 p.

Spike after-depolarization and burst generation in adult rat hippocampal CA1 pyramidal cells

Jensen, M. S., Azouz, R. & Yaari, Y., 1996, In : Journal of Physiology. 492 ( Pt 1), p. 199-210 11 p.

Muscarinic modulation of intrinsic burst firing in rat hippocampal neurons

Azouz, R., Jensen, M. S. & Yaari, Y., 1994, In : European Journal of Neuroscience. 6, 6, p. 961-6 5 p.

Nervecellernes aktivitet ved epileptiske anfald

Andreasen, M. & Jensen, M. S., 1994, In : Lægemiddelforskning. p. 20-23

Variant firing patterns in rat hippocampal pyramidal cells modulated by extracellular potassium

Jensen, M. S., Azouz, R. & Yaari, Y., 1994, In : Journal of Neurophysiology. 71, 3, p. 831-9 8 p.

Opponent effects of potassium on GABAA-mediated postsynaptic inhibition in the rat hippocampus

Jensen, M. S., Cherubini, E. & Yaari, Y., 1993, In : Journal of Neurophysiology. 69, 3, p. 764-71 7 p.

Interictal activity induces long-term enhancement of excitatory postsynaptic potentials in the hippocampus

Azouz, R., Jensen, M. S. & Yaari, Y., 1992, In : Epilepsy Research Supplements. 9, p. 313-6; discussion 316-7

Two types of epileptic foci generating brief and sustained paroxysms in the in vitro rat hippocampus

Yaari, Y. & Jensen, M. S., 1992, In : Epilepsy Research Supplements. 8, p. 263-9 6 p.

Electrophysiological recordings from rat hippocampus slices following in vivo brain ischemia

Jensen, M. S., Lambert, J. D. & Johansen, F. F., 1991, In : Brain Research. 554, 1-2, p. 166-75 9 p.

Enhanced synaptic activation of NMDA receptors during hippocampal seizures

Yaari, Y., Jensen, M. S., Perouansky, M., Keller, B. U. & Konnerth, A., 1991, In : Journal of Basic and Clinical Physiology and Pharmacology. 1, 1-4, p. 41-7 6 p.

Inhibition in postischemic rat hippocampus: GABA receptors, GABA release, and inhibitory postsynaptic potentials

Johansen, F. F., Christensen, T., Jensen, M. S., Valente, E., Jensen, C. V., Nathan, T., Lambert, J. D. & Diemer, N. H., 1991, In : Experimental Brain Research. 84, 3, p. 529-37 8 p.

GABAB receptors play a major role in paired-pulse facilitation in area CA1 of the rat hippocampus

Nathan, T., Jensen, M. S. & Lambert, J. D., 1990, In : Brain Research. 531, 1-2, p. 55-65 10 p.

The slow inhibitory postsynaptic potential in rat hippocampal CA1 neurones is blocked by intracellular injection of QX-314

Nathan, T., Jensen, M. S. & Lambert, J. D., 1990, In : Neuroscience Letters. 110, 3, p. 309-13 4 p.

A functional study of the effects of new non-NMDA antagonists in the rat hippocampus in vitro

Andreasen, M., Jensen, M. S. & Lambert, J. D. C., 1989, In : Acta Neurologica Scandinavia. 80, p. 359

Cholinergic modulation of hippocampal epileptic activity in vitro

Yaari, Y. & Jensen, M. S., 1989, In : E X S. 57, p. 150-8 8 p.

Effects of new non-N-methyl-D-aspartate antagonists on synaptic transmission in the in vitro rat hippocampus

Andreasen, M., Lambert, J. D. & Jensen, M. S., 1989, In : Journal of Physiology. 414, p. 317-36 19 p.

The role of excitatory amino acids in synaptic transmission in the hippocampus

Lambert, J. D., Jones, R. S., Andreasen, M., Jensen, M. S. & Heinemann, U., 1989, In : Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology. 93, 1, p. 195-201 6 p.

Direct demonstration of an N-methyl-D-aspartate receptor mediated component of excitatory synaptic transmission in area CA1 of the rat hippocampus

Andreasen, M., Lambert, J. D. & Jensen, M. S., 1988, In : Neuroscience Letters. 93, 1, p. 61-6 5 p.

The relationship between interictal and ictal paroxysms in an in vitro model of focal hippocampal epilepsy

Jensen, M. S. & Yaari, Y., 1988, In : Annals of Neurology. 24, 5, p. 591-8 7 p.

Electrophysiological studies in cultured mouse CNS neurones of the actions of an agonist and an inverse agonist at the benzodiazepine receptor

Jensen, M. S. & Lambert, J. D., 1986, In : British Journal of Pharmacology. 88, 4, p. 717-31 14 p.

Modulation of the responses to the GABA-mimetics, THIP and piperidine-4-sulphonic acid, by agents which interact with benzodiazepine receptors. An electrophysiological study on cultured mouse neurones

Jensen, M. S. & Lambert, J. D., 1984, In : Neuropharmacology. 23, 12A, p. 1441-50 9 p.

The interaction of the beta-carboline derivative DMCM with inhibitory amino acid responses on cultured mouse neurones

Jensen, M. S. & Lambert, J. D., 1983, In : Neuroscience Letters. 40, 2, p. 175-9 4 p.