Department of Management

Morten Berg Jensen

Health-related quality-of-life in patients after elective surgery for abdominal aortic aneurysm

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Health-related quality-of-life in patients after elective surgery for abdominal aortic aneurysm. / Ehlers, Lars ; Laursen, Kathrine Bang ; Jensen, Morten Berg.

In: Journal of Medical Economics, Vol. 14, No. 6, 2011, p. 787–791.

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Ehlers, Lars ; Laursen, Kathrine Bang ; Jensen, Morten Berg. / Health-related quality-of-life in patients after elective surgery for abdominal aortic aneurysm. In: Journal of Medical Economics. 2011 ; Vol. 14, No. 6. pp. 787–791.

Bibtex

@article{c68f176d2ba04a8981163c4b6fab5482,
title = "Health-related quality-of-life in patients after elective surgery for abdominal aortic aneurysm",
abstract = "Purpose: The purpose of this study was to describe the health-related quality-of-life (QoL) in patients after elective surgery for abdominal aortic aneurysm (AAA) compared to a normal population and to study the association between QoL and number of years since surgery. Methods: All Danish men who underwent elective surgery for AAA at the age of 65 or more in the period from 1989–2007 in Denmark were invited to participate in the survey. Of 722 patients, 375 were alive and 328 (87{\%}) responded. The nstruments EQ-5D (European Quality of life), EQ-VAS and SF-12 (Short Form Health Survey) were applied for measuring health-related QoL. Multiple regression analysis was used to study the association between QoL and number of years since AAA surgery. Results: A significantly poorer QoL was found in patients having had AAA surgery compared to the normal population as measured with the SF-12 and the EQ-VAS, but not with EQ-5D. A negative association between QoL and years following surgery was found with EQ-VAS and SF-12 (PCS), but not with the other instruments. Discussion: Factors such as selection bias because of mortality and non-response may have resulted in an over-estimate of the QoL in patients having had AAA surgery, thus the difference in QoL compared to the normal population was probably under-estimated. The cross-section design was inefficient for the study of the association between QoL and years since surgery, and EQ-5D may be an insensitive instrument for measuring QoL in AAA patients after surgery. Limitations: The main limitation of the study was the cross-sectional design. Males with a higher risk of death were under-represented in the sample. Conclusion: A poorer quality-of-life was found in patients having had elective AAA surgery compared to the normal population.",
keywords = "Cost effectiveness, Quality-of-life , Abdominal aortic aneurysm, EQ-5D",
author = "Lars Ehlers and Laursen, {Kathrine Bang} and Jensen, {Morten Berg}",
year = "2011",
doi = "10.3111/13696998.2011.626822",
language = "English",
volume = "14",
pages = "787–791",
journal = "Journal of Medical Economics",
issn = "1369-6998",
publisher = "Taylor & francis",
number = "6",

}

RIS

TY - JOUR

T1 - Health-related quality-of-life in patients after elective surgery for abdominal aortic aneurysm

AU - Ehlers, Lars

AU - Laursen, Kathrine Bang

AU - Jensen, Morten Berg

PY - 2011

Y1 - 2011

N2 - Purpose: The purpose of this study was to describe the health-related quality-of-life (QoL) in patients after elective surgery for abdominal aortic aneurysm (AAA) compared to a normal population and to study the association between QoL and number of years since surgery. Methods: All Danish men who underwent elective surgery for AAA at the age of 65 or more in the period from 1989–2007 in Denmark were invited to participate in the survey. Of 722 patients, 375 were alive and 328 (87%) responded. The nstruments EQ-5D (European Quality of life), EQ-VAS and SF-12 (Short Form Health Survey) were applied for measuring health-related QoL. Multiple regression analysis was used to study the association between QoL and number of years since AAA surgery. Results: A significantly poorer QoL was found in patients having had AAA surgery compared to the normal population as measured with the SF-12 and the EQ-VAS, but not with EQ-5D. A negative association between QoL and years following surgery was found with EQ-VAS and SF-12 (PCS), but not with the other instruments. Discussion: Factors such as selection bias because of mortality and non-response may have resulted in an over-estimate of the QoL in patients having had AAA surgery, thus the difference in QoL compared to the normal population was probably under-estimated. The cross-section design was inefficient for the study of the association between QoL and years since surgery, and EQ-5D may be an insensitive instrument for measuring QoL in AAA patients after surgery. Limitations: The main limitation of the study was the cross-sectional design. Males with a higher risk of death were under-represented in the sample. Conclusion: A poorer quality-of-life was found in patients having had elective AAA surgery compared to the normal population.

AB - Purpose: The purpose of this study was to describe the health-related quality-of-life (QoL) in patients after elective surgery for abdominal aortic aneurysm (AAA) compared to a normal population and to study the association between QoL and number of years since surgery. Methods: All Danish men who underwent elective surgery for AAA at the age of 65 or more in the period from 1989–2007 in Denmark were invited to participate in the survey. Of 722 patients, 375 were alive and 328 (87%) responded. The nstruments EQ-5D (European Quality of life), EQ-VAS and SF-12 (Short Form Health Survey) were applied for measuring health-related QoL. Multiple regression analysis was used to study the association between QoL and number of years since AAA surgery. Results: A significantly poorer QoL was found in patients having had AAA surgery compared to the normal population as measured with the SF-12 and the EQ-VAS, but not with EQ-5D. A negative association between QoL and years following surgery was found with EQ-VAS and SF-12 (PCS), but not with the other instruments. Discussion: Factors such as selection bias because of mortality and non-response may have resulted in an over-estimate of the QoL in patients having had AAA surgery, thus the difference in QoL compared to the normal population was probably under-estimated. The cross-section design was inefficient for the study of the association between QoL and years since surgery, and EQ-5D may be an insensitive instrument for measuring QoL in AAA patients after surgery. Limitations: The main limitation of the study was the cross-sectional design. Males with a higher risk of death were under-represented in the sample. Conclusion: A poorer quality-of-life was found in patients having had elective AAA surgery compared to the normal population.

KW - Cost effectiveness

KW - Quality-of-life

KW - Abdominal aortic aneurysm

KW - EQ-5D

U2 - 10.3111/13696998.2011.626822

DO - 10.3111/13696998.2011.626822

M3 - Journal article

C2 - 21981560

VL - 14

SP - 787

EP - 791

JO - Journal of Medical Economics

JF - Journal of Medical Economics

SN - 1369-6998

IS - 6

ER -