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Mika Erik Tapio Sillanpää
High-sensitivity biosensor based on glass resonance PhC cavities for detection of blood component and glucose concentration in human urine
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In: Coatings, Vol. 11, No. 12, 1555, 12.2021.
Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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TY - JOUR
T1 - High-sensitivity biosensor based on glass resonance PhC cavities for detection of blood component and glucose concentration in human urine
AU - Jalil, Abduladheem Turki
AU - Ashfaq, Shameen
AU - Bokov, Dmitry Olegovich
AU - Alanazi, Amer M.
AU - Hachem, Kadda
AU - Suksatan, Wanich
AU - Sillanpää, Mika
N1 - Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/12
Y1 - 2021/12
N2 - In this work, a novel structure of an all-optical biosensor based on glass resonance cavities with high detection accuracy and sensitivity in two-dimensional photon crystal is designed and simulated. The free spectral range in which the structure performs well is about FSR = 630 nm. This sensor measures the concentration of glucose in human urine. Analyses to determine the glucose concentration in urine for a normal range (0~15 mg/dL) and urine despite glucose concentrations of 0.625, 1.25, 2.5, 5 and 10 g/dL in the wavelength range 1.326404~1.326426 μm have been conducted. The detection range is RIU = 0.2 × 10−7. The average bandwidth of the output resonance wavelengths is 0.34 nm in the lowest case. In the worst case, the percentage of optical signal power transmission is 77% with an amplitude of 1.303241 and, in the best case, 100% with an amplitude of 1.326404. The overall dimensions of the biosensor are 102.6 μm2 and the sensitivity is equal to S = 1360.02 nm/RIU and the important parameter of the Figure of Merit (FOM) for the proposed biosensor structure is equal to FOM = 1320.23 RIU−1.
AB - In this work, a novel structure of an all-optical biosensor based on glass resonance cavities with high detection accuracy and sensitivity in two-dimensional photon crystal is designed and simulated. The free spectral range in which the structure performs well is about FSR = 630 nm. This sensor measures the concentration of glucose in human urine. Analyses to determine the glucose concentration in urine for a normal range (0~15 mg/dL) and urine despite glucose concentrations of 0.625, 1.25, 2.5, 5 and 10 g/dL in the wavelength range 1.326404~1.326426 μm have been conducted. The detection range is RIU = 0.2 × 10−7. The average bandwidth of the output resonance wavelengths is 0.34 nm in the lowest case. In the worst case, the percentage of optical signal power transmission is 77% with an amplitude of 1.303241 and, in the best case, 100% with an amplitude of 1.326404. The overall dimensions of the biosensor are 102.6 μm2 and the sensitivity is equal to S = 1360.02 nm/RIU and the important parameter of the Figure of Merit (FOM) for the proposed biosensor structure is equal to FOM = 1320.23 RIU−1.
KW - Glucose concentration
KW - High-sensitivity
KW - Optical biosensors
KW - Quality factor
UR - http://www.scopus.com/inward/record.url?scp=85121450032&partnerID=8YFLogxK
U2 - 10.3390/coatings11121555
DO - 10.3390/coatings11121555
M3 - Journal article
AN - SCOPUS:85121450032
VL - 11
JO - Coatings
JF - Coatings
SN - 2079-6412
IS - 12
M1 - 1555
ER -