Michael Sørensen

  1. 2021
  2. Accepted/In press

    Hepatic blood flow in adult Göttingen minipigs and pre-pubertal Danish Landrace x Yorkshire pigs. / Kjærgaard, Kristoffer; Sørensen, Michael; Mortensen, Frank Viborg; Alstrup, Aage Kristian Olsen.

    In: Laboratory Animals, 15.02.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Obeticholic acid improves hepatic bile acid excretion in patients with primary biliary cholangitis. / Kjærgaard, Kristoffer; Frisch, Kim; Sørensen, Michael; Munk, Ole Lajord; Hofmann, Alan Frederick; Horsager, Jacob; Schacht, Anna Christina; Erickson, Mary; Shapiro, David A.; Keiding, Susanne.

    In: Journal of Hepatology, Vol. 74, No. 1, 01.2021, p. 58-65.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. 2020
  5. Published
  6. Published
  7. 2019
  8. Published

    Obeticholic acid improves hepatobiliary excretion of bile acids in patients with PBC. / Kjærgaard, Kristoffer; Frisch, Kim; Munk, Ole Lajord; Hofmann, Alan F.; Sørensen, Michael; Horsager, Jacob; Erickson, Mary; Shapiro, David A.; Keiding, Susanne.

    2019. Poster session presented at The Liver Meeting, Boston, United States.

    Research output: Contribution to conferencePosterResearchpeer-review

  9. Published

    Non-alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion. / Eriksen, Peter Lykke; Vilstrup, Hendrik; Rigbolt, Kristoffer; Suppli, Malte Palm; Sørensen, Michael; Heebøll, Sara; Veidal, Sanne Skovgård; Knop, Fillip Krag; Thomsen, Karen Louise.

    In: Liver International, Vol. 39, No. 11, 11.2019, p. 2094-2101.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    NON-ALCOHOLIC FATTY LIVER DISEASE ALTERS EXPRESSION OF GENES GOVERNING HEPATIC NITROGEN CONVERSION. / Eriksen, Peter Lykke; Vilstrup, Hendrik Von Arenstorff; Rigbolt, Kristoffer; Suppli, Malte; Sorensen, Michael; Veidal, Sanne; Knop, Filip Krag; Thomsen, Karen Louise.

    2019. 1351A-1351A Poster session presented at Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, Boston, Morocco.

    Research output: Contribution to conferencePosterResearchpeer-review

  11. Published

    Non-alcoholic fatty liver disease causes dissociated changes in metabolic liver functions. / Eriksen, Peter Lykke; Sørensen, Michael; Grønbæk, Henning; Hamilton-Dutoit, Stephen; Vilstrup, Hendrik; Thomsen, Karen Louise.

    In: Clinics and Research in Hepatology and Gastroenterology, Vol. 43, No. 5, 10.2019, p. 551-560.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Non-alcoholic steatohepatitis, but not simple steatosis, disturbs the functional homogeneity of the liver - a human galactose positron emission tomography study. / Eriksen, Peter Lykke; Thomsen, Karen Louise; Larsen, Lars Peter; Grønbaek, Henning; Vilstrup, Hendrik; Sørensen, Michael.

    In: Alimentary Pharmacology and Therapeutics, Vol. 50, No. 1, 07.2019, p. 84-92.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Noncirrotisk portal hypertension. / Sørensen, Michael; Grønbæk, Henning.

    In: Ugeskriftet.dk, No. 13, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperComment/debateResearch

  14. Published

    [18F]-Fluoro-2-deoxy-D-galactose positron emission tomography/computed tomography as complementary imaging tool in patients with hepatocellular carcinoma. / Bak-Fredslund, Kirstine P.; Keiding, Susanne; Villadsen, Gerda E.; Kramer, Stine; Schlander, Sven; Sørensen, Michael.

    In: Liver International, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. 2018
  16. Published
  17. Published

    β-Blockers Improve Presinusoidal Portal Hypertension. / Sørensen, Michael; Larsen, Lars P; Villadsen, Gerda E; Aagaard, Niels K; Grønbæk, Henning; Keiding, Susanne; Vilstrup, Hendrik.

    In: Digestive Diseases and Sciences, Vol. 63, No. 11, 11.2018, p. 3153-3157.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Functional assessment of hepatobiliary secretion by 11C-cholylsarcosine positron emission tomography. / Ørntoft, Nikolaj; Frisch, Kim; Ott, Peter; Keiding, Susanne; Sørensen, Michael.

    In: B B A - Molecular Basis of Disease, Vol. 1864, No. 4, Part B, 04.2018, p. 1240-1244.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  19. Published

    Quantitative PET of liver functions. / Keiding, Susanne; Sørensen, Michael; Frisch, Kim; Gormsen, Lars C; Munk, Ole Lajord.

    In: American Journal of Nuclear Medicine and Molecular Imaging, Vol. 8, No. 2, 2018, p. 73-85.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  20. 2017
  21. Published

    A phase I study on stereotactic body radiotherapy of liver metastases based on functional treatment planning using positron emission tomography with 2-[(18)F]fluoro-2-deoxy-d-galactose. / Fode, Mette Marie; Bak-Fredslund, Kirstine; Petersen, Jørgen Baltzer; Worm, Esben; Sørensen, Michael; Høyer, Morten.

    In: Acta Oncologica, Vol. 56, No. 11, 11.2017, p. 1614-1620.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Metabolic liver function in humans measured by 2-(18)F-fluoro-2-deoxy-D-galactose PET/CT-reproducibility and clinical potential. / Bak-Fredslund, Kirstine P; Lykke Eriksen, Peter; Munk, Ole L; Villadsen, Gerda E; Keiding, Susanne; Sørensen, Michael.

    In: EJNMMI research, Vol. 7, No. 1, 29.08.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Hepatobiliary transport kinetics of the conjugated bile acid tracer 11C-CSar quantified in healthy humans and patients by positron emission tomography. / Ørntoft, Nikolaj Worm; Munk, Ole Lajord; Frisch, Kim; Ott, Peter; Keiding, Susanne; Sørensen, Michael.

    In: Journal of Hepatology, Vol. 67, No. 2, 08.2017, p. 321-327.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    2-[18F]fluoro-2-deoxy-d-galactose positron emission tomography guided functional treatment planning of stereotactic body radiotherapy of liver tumours. / Fode, Mette Marie; Petersen, Jørgen B.B.; Sørensen, Michael; Holt, Marianne Ingerslev; Keiding, Susanne; Høyer, Morten.

    In: Physics and Imaging in Radiation Oncology, Vol. 1, 01.2017, p. 28-33.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. 2016
  26. Published

    2-[(18)F]fluoro-2-deoxy-D-galactose PET/CT of hepatocellular carcinoma is not improved by co-administration of galactose. / Bak-Fredslund, Kirstine P; Munk, Ole Lajord; Keiding, Susanne; Sørensen, Michael.

    In: Nuclear Medicine and Biology, Vol. 43, No. 9, 09.2016, p. 577-80.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Hepatobiliary Secretion Kinetics of Conjugated Bile Acids Measured in Pigs by 11C-Cholylsarcosine PET. / Sørensen, Michael; Munk, Ole Lajord; Oerntoft, Nikolaj; Frisch, Kim; Andersen, Kasper Jarlhelt; Mortensen, Frank Viborg; Alstrup, Aage Kristian Olsen; Ott, Peter; Hofmann, Alan Frederick; Keiding, Susanne.

    In: The Journal of Nuclear Medicine, Vol. 57, No. 6, 06.2016, p. 961-966.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. 2015
  29. Published

    Methodologic Considerations for Quantitative 18F-FDG PET/CT Studies of Hepatic Glucose Metabolism in Healthy Subjects. / Trägårdh, Malene; Møller, Niels; Sørensen, Michael.

    In: Journal of Nuclear Medicine, Vol. 56, No. 9, 09.2015, p. 1366-71.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Metabolic liver function measured in vivo by dynamic (18)F-FDGal PET/CT without arterial blood sampling. / Nielsen, Jacob Horsager; Munk, Ole Lajord; Sørensen, Michael.

    In: EJNMMI research, Vol. 5, 2015, p. 32.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. 2014
  32. Published

    Development of carbon-11 labelled N-methyl-taurine conjugated bile acids as PET-tracers for measuring hepatic secretion of bile acids. / Schacht, Anna Christina; Sørensen, Michael; Munk, Ole Lajord; Frisch, Kim.

    2014. Poster session presented at Falk Symposium 194, XXIII International Bile Acid Meeting, Freiburg, Germany.

    Research output: Contribution to conferencePosterResearchpeer-review

  33. Published

    Oxidative metabolism of astrocytes is not reduced in hepatic encephalopathy : a PET study with [(11)C]acetate in humans. / Iversen, Peter; Mouridsen, Kim; Hansen, Mikkel Bo; Jensen, Svend B; Sørensen, Michael; Bak, Lasse K; Waagepetersen, Helle S; Schousboe, Arne; Ott, Peter; Vilstrup, Hendrik; Keiding, Susanne; Gjedde, Albert.

    In: Frontiers in Neuroscience, Vol. 8, 2014, p. 353.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Oxidative metabolism of astrocytes is not reduced in hepatic encephalopathy: a PET study with [11C]acetate in humans. / Iversen, Peter; Mouridsen, Kim; Hansen, Mikkel Bo; Jensen, Svend Borup; Sørensen, Michael; Bak, Lasse Kristoffer; Waagepetersen, Helle S; Schousboe, Arne; Ott, Peter; Vilstrup, Hendrik; Keiding, Susanne; Gjedde, Albert.

    In: Frontiers in Neuroscience, Vol. 8, 353, 2014, p. 1-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. 2013
  36. Published

    Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia : effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures. / Dadsetan, Sherry; Kukolj, Eva; Bak, Lasse Kristoffer; Sørensen, Michael; Ott, Peter; Vilstrup, Hendrik; Schousboe, Arne; Keiding, Susanne; Waagepetersen, Helle S.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 33, No. 8, 08.2013, p. 1235-41.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Regional metabolic liver function measured in patients with cirrhosis by 2-[¹⁸F]fluoro-2-deoxy-D-galactose PET/CT. / Sørensen, Michael; Mikkelsen, Kasper Sandager; Frisch, Kim; Villadsen, Gerda E; Keiding, Susanne.

    In: Journal of Hepatology, Vol. 58, No. 6, 06.2013, p. 1119-24.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    Role of branched chain amino acids in cerebral ammonia homeostasis related to hepatic encephalopathy. / Bak, Lasse Kristoffer; Waagepetersen, Helle S.; Sørensen, Michael; Ott, Peter; Vilstrup, Hendrik; Keiding, Susanne; Schousboe, Arne.

    In: Metabolic Brain Disease, Vol. 28, No. 2, 06.2013, p. 209-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    Update on cerebral uptake of blood ammonia. / Sørensen, Michael.

    In: Metabolic Brain Disease, Vol. 28, No. 2, 06.2013, p. 155-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    Positron emission tomography of hepatobiliary transport: development of 11C-cholylsarcosine, a PET-tracer for conjugated bile acids. / Frisch, Kim; Sørensen, Michael; Hofmann, Alan; Keiding, Susanne.

    XXII International Bile Acid Meeting - Hepatic and Extrahepatic Targets of Bile Acid Signaling. Falk Symposium 184, Vienna, 2012. Karger Medical and Scientific Publishers, 2013. p. 96-103.

    Research output: Contribution to book/anthology/report/proceedingArticle in proceedingsResearchpeer-review

  41. Published

    Regional metabolic liver function measured by 2-[18F]fluoro-2-deoxy-D-galactose PET/CT in patients with cirrhosis. / Sørensen, Michael; Sandager Mikkelsen, Kasper; Frisch, Kim; Villadsen, Gerda Elisabeth; Keiding, Susanne.

    In: Journal of Hepatology, Vol. 58, 2013, p. 1119−1124.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. 2012
  43. Published
  44. Published

    Calculating the metabolic clearance of a mother substance from the clearance of it´s analogue tracer measured by PET. / Bass, Ludvik; Sørensen, Michael; Munk, Ole Lajord; Keiding, Susanne.

    Functional Molecular Imaging in Hepatology. ed. / Susanne Keiding; Michael Sørensen. Bentham Science Publishers, 2012. p. 32-36.

    Research output: Contribution to book/anthology/report/proceedingBook chapterCommunication

  45. Published

    Carbon-11 labelled cholylsarcosine: a PET-tracer for conjugated bile acids. / Frisch, Kim; Jakobsen, Steen; Sørensen, Michael; Munk, Ole Lajord; Alstrup, Aage Kristian Olsen; Ott, Peter; Hofmann, Alan F. ; Keiding, Susanne.

    2012. Poster session presented at Falk Symposium 184, XXII International Bile Acid Meeting, Wien, Austria.

    Research output: Contribution to conferencePosterResearchpeer-review

  46. Published

    Carbon-11 labelling of cholylsarcosine and in vivo imaging of conjugated bile acids by positron emission tomography. / Frisch, Kim; Jakobsen, Steen; Sørensen, Michael; Munk, Ole Lajord; Alstrup, Aage Kristian Olsen; Ott, Peter; Hofmann, Alan F.; Keiding, Susanne.

    2012. Poster session presented at Danish Chemical Society, Odense, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  47. Published

    Functional Molecular Imaging in Hepatoloy. / Keiding, Susanne (Editor); Sørensen, Michael (Editor).

    Bentham Science Publishers, 2012. 185 p.

    Research output: Book/anthology/dissertation/reportBookCommunication

  48. Published

    Hepatic blood perfusion estimated by dynamic contrast-enhanced computer tomography in pigs : Limitations of the slope method. / Winterdahl, Michael; Sørensen, Michael; Keiding, Susanne; Mortensen, Frank Viborg; Alstrup, Aage Kristian Olsen; Hansen, Søren Baarsgaard; Munk, Ole Lajord.

    In: Investigative Radiology, Vol. 47, No. 10, 2012, p. 588-595.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  49. Published

    Reply to letter to the editor by Zheng G et al : Venous blood ammonia can be associated with cerebral blood flow in hepatic encephalopathy. / Dam, Gitte; Keiding, Susanne; Munk, Ole L; Ott, Peter; Vilstrup, Hendrik; Bak, Lasse Kristoffer; Waagepetersen, Helle S.; Schousboe, Arne; Sørensen, Michael.

    In: Hepatology, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    [N-methyl-11C]cholylsarcosine, a novel bile acid tracer for PET/CT of hepatic excretory function : Radiosynthesis and proof-of-concept studies in pigs. / Frisch, Kim; Jakobsen, Steen; Sørensen, Michael; Munk, Ole Lajord; Alstrup, Aage K O; Ott, Peter; Hofmann, Alan F; Keiding, Susanne.

    In: Journal of Nuclear Medicine, Vol. 53, No. 5, 2012, p. 772-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. 2011
  52. Published

    Analogue tracers and lumped constant in capillary beds. / Bass, Ludvik; Sørensen, Michael; Munk, Ole Lajord; Keiding, Susanne.

    In: Journal of Theoretical Biology, Vol. 285, No. 1, 21.09.2011, p. 177-181.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons. / Dadsetan, Sherry; Bak, Lasse Kristoffer; Sørensen, Michael; Keiding, Susanne; Vilstrup, Hendrik; Ott, Peter; Leke, Renata; Schousboe, Arne; Waagepetersen, Helle S.

    In: Neurochemistry International, Vol. 59, No. 4, 01.09.2011, p. 482-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  54. Published

    The potential use of 2-[18F]fluoro-2-deoxy-D-galactose as a PET/CT tracer for detection of hepatocellular carcinoma. / Sørensen, Michael; Frisch, Kim; Bender, Dirk; Keiding, Susanne.

    In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 38, No. 9, 09.2011, p. 1723-1731.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  55. Published

    Hepatic galactose metabolism quantified in humans using 2-18F-fluoro-2-deoxy-D-galactose PET/CT. / Sørensen, Michael; Mikkelsen, Kasper Sandager; Frisch, Kim; Bass, Ludvik; Bibby, Bo Martin; Keiding, Susanne.

    In: Journal of Nuclear Medicine, Vol. 52, No. 10, 29.08.2011, p. 1566-1572.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  56. Published

    Hepatic blood perfusion measured by 3-minute dynamic 18F-FDG PET in pigs. / Winterdahl, Michael; Munk, Ole Lajord; Sørensen, Michael; Mortensen, Frank Viborg; Keiding, Susanne.

    In: Journal of Nuclear Medicine, Vol. 52, No. 7, 07.2011, p. 1119-1124.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. Published

    Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy. / Leke, Renata; Bak, Lasse Kristoffer; Iversen, Peter; Sørensen, Michael; Keiding, Susanne; Vilstrup, Hendrik; Ott, Peter; Portela, Luis V; Schousboe, Arne; Waagepetersen, Helle S.

    In: Journal of Neurochemistry, Vol. 117, No. 5, 01.06.2011, p. 824-32.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  58. Published

    Nucleophilic radiosynthesis of 2-[18F]fluoro-2-deoxy-D-galactose from Talose triflate and biodistribution in a porcine model. / Frisch, Kim; Bender, Dirk; Keiding, Susanne; Sørensen, Michael.

    In: Nuclear Medicine and Biology, Vol. 38, No. 4, 05.2011, p. 477-483.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  59. Published

    Detoxification of Ammonia in Mouse Cortical GABAergic Cell Cultures Increases Neuronal Oxidative Metabolism and Reveals an Emerging Role for Release of Glucose-Derived Alanine. / Leke, Renata; Bak, Lasse K; Anker, Malene; Melø, Torun M; Sørensen, Michael; Keiding, Susanne; Vilstrup, Hendrik; Ott, Peter; Portela, Luis V; Sonnewald, Ursula; Schousboe, Arne; Waagepetersen, Helle S.

    In: Neurotoxicity Research, Vol. 19, No. 3, 01.04.2011, p. 496-510.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  60. Published

    Determination of hepatic galactose elimination capacity using 2-[¹⁸F]fluoro-2-deoxy-D-galactose PET/CT: reproducibility of the method and metabolic heterogeneity in a normal pig liver model. / Sørensen, Michael.

    In: Scandinavian Journal of Gastroenterology, Vol. 46, No. 1, 01.01.2011, p. 98-103.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  61. Published

    Tracer input for kinetic modelling of liver physiology determined without sampling portal venous blood in pigs. / Winterdahl, Michael; Keiding, Susanne; Sørensen, Michael; Mortensen, Frank Viborg; Alstrup, Aage Kristian Olsen; Munk, Ole Lajord.

    In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 38, No. 2, 2011, p. 263-270.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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