Projects per year
Personal profile
Profile
I work as a lab manager at the Department of Forensic Medicine. As such I'm involved in different research areas, including post translational modifications of proteins related to aging and diabetes, as well as pharmacological characterization of psychoactive compounds and photo-pharmacology.
Job responsibilities
I support the research groups in rthe Bioanalytical Unit at the department of Forensic Medicine. I’m involved in research projects and supervision of students. I help establish and ensure continuation of different methods, including cell based assays to measure GPCR activity. I’m involved in proteomics studies and measurements of peptide reactivity towards metabolites. I’m responsible for running the research laboratories, including purchase of supplies.
Education/Academic qualification
Structural Biology, PhD, Structural studies of the yeast peroxiredoxin TSA2, Aarhus University
1 Feb 2013 → 31 Jan 2016
Award Date: 15 May 2016
Medicinal Chemisrty, Master of Science, Functional and allosteric consequences of serotonin transporter dimerization, Aarhus University
1 Aug 2010 → 19 Oct 2012
Award Date: 19 Oct 2012
Medicinal Chemistry, Bachelor degree, Evaluation of sulphur- and selenoanalogues of citalopram and imipramine as novel antidepressants
1 Aug 2007 → 1 Aug 2010
Award Date: 1 Aug 2010
External positions
Scientist, IFF
1 Nov 2018 → 31 Oct 2019
High School Teacher Chemistry, Danish Gymnasium/HF/VUC/Vocational School
1 Nov 2017 → 30 Jun 2018
Keywords
- Cerebral and nervous system
- Biological stressors
Areas of expertise
- Photopharmacology
- psychoactive compounds
- posttranslational modifications
- Proteomics
- wastewater analysis
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Collaborations and top research areas from the last five years
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Projects
- 1 Finished
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PhD project: Structural studies of the yeast peroxiredoxin TSA2
Nielsen, M. H. (Participant)
01/02/2013 → 12/02/2016
Project: Research
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Structure of TSA2 reveals novel features of the active-site loop of peroxiredoxins
Nielsen, M. H., Kidmose, R. T. & Jenner, L. B., 2016, In: Acta crystallographica Section D: Structural biology . 72, 1, p. 158-167 10 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
11 Citations (Scopus) -
Structural analysis of ribosomal RACK1 and its role in translational control
Nielsen, M. H., Flygaard, R. K. & Jenner, L. B., 1 Jul 2017, In: Cellular Signalling. 35, p. 272-281 10 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
48 Citations (Scopus) -
Structural studies of the yeast peroxiredoxin TSA2
Nielsen, M. H., 31 May 2016, Aarhus University, Science and Technology.Research output: Types of Thesis › PhD thesis
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Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System
Bertelsen, M. B., Senissar, M., Nielsen, M. H., Bisiak, F., Cunha, M. V., Molinaro, A. L., Daines, D. A. & Brodersen, D. E., Feb 2021, In: Structure. 29, 2, p. 139-150.e3Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access16 Citations (Scopus)