Martin Roelsgaard Jakobsen

  1. 2022
  2. Published

    Plasmacytoid Dendritic Cells as a Novel Cell-Based Cancer Immunotherapy. / Hernández, Sabina Sánchez; Jakobsen, Martin Roelsgaard; Bak, Rasmus O.

    In: International Journal of Molecular Sciences , Vol. 23, No. 19, 11397, 09.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer. / Sokac, Mateo; Ahrenfeldt, Johanne; Litchfield, Kevin et al.

    In: Cancer Research Communications, Vol. 2, No. 8, 08.2022, p. 762-771.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Increased Soluble PD-1 Predicts Response to Nivolumab plus Ipilimumab in Melanoma. / Pedersen, Jesper Geert; Sokac, Mateo; Sørensen, Boe Sandahl et al.

    In: Cancers, Vol. 14, No. 14, 3342, 07.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Plasmacytoid dendritic cells during COVID-19 : Ally or adversary? / van der Sluis, Renée Marije; Holm, Christian Kanstrup; Jakobsen, Martin Roelsgaard.

    In: Cell Reports, Vol. 40, No. 4, 111148, 07.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  6. Published

    IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection. / Griffante, Gloria; Hewelt-Belka, Weronika; Albano, Camilla et al.

    In: mBio, Vol. 13, No. 3, 06.2022, p. e0043522.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS-CoV-2 infection. / van der Sluis, Renée M.; Cham, Lamin B.; Gris-Oliver, Albert et al.

    In: EMBO Journal, Vol. 41, No. 10, e109622, 05.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. 2021
  9. Published

    Phenotypic and functional characterization of synovial fluid-derived fibroblast-like synoviocytes in rheumatoid arthritis. / Køster, Ditte; Egedal, Johanne Hovgaard; Lomholt, Søren et al.

    In: Scientific Reports, Vol. 11, No. 1, 22168, 12.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern. / Carter-Timofte, Madalina Elena; Arulanandam, Rozanne; Kurmasheva, Naziia et al.

    In: ACS Infectious Diseases, Vol. 7, No. 11, 10.2021, p. 3034-3051.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells. / Laustsen, Anders; van der Sluis, Renée Marije; Gris Oliver, Albert et al.

    In: eLife, Vol. 10, e65528, 09.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection. / Egedal, Johanne H; Xie, Guorui; Packard, Thomas A et al.

    In: Mucosal Immunology, Vol. 14, No. 5, 09.2021, p. 1203-1213.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Macrodiolide Diversification Reveals Broad Immunosuppressive Activity That Impairs the cGAS-STING Pathway. / Liu, Han; Ottosen, Rasmus N; Jennet, Kira M et al.

    In: Angewandte Chemie International Edition, Vol. 60, No. 34, 08.2021, p. 18734-18741.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    cGAS-STING pathway expression as a prognostic tool in NSCLC. / Raaby Gammelgaard, Kristine; Sandfeld-Paulsen, Birgitte; Godsk, Stine Høvring et al.

    In: Translational lung cancer research, Vol. 10, No. 1, 01.2021, p. 340-354.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Cell-Extrinsic Priming Increases Permissiveness of CD4+ T Cells to Human Immunodeficiency Virus Infection by Increasing C-C Chemokine Receptor Type 5 Co-receptor Expression and Cellular Activation Status. / Pedersen, Jesper G; Egedal, Johanne H; Packard, Thomas A et al.

    In: Frontiers in Microbiology, Vol. 12, 763030, 2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. 2020
  17. Published

    Author Correction : SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate. / Olagnier, David; Farahani, Ensieh; Thyrsted, Jacob et al.

    In: Nature Communications, Vol. 11, No. 1, 5419, 21.10.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperComment/debate/letter to the editorResearchpeer-review

  18. Published

    SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate. / Olagnier, David; Farahani, Ensieh; Thyrsted, Jacob et al.

    In: Nature Communications, Vol. 11, No. 1, 4938, 10.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Inflammatory Cytokines and ctDNA Are Biomarkers for Progression in Advanced-Stage Melanoma Patients Receiving Checkpoint Inhibitors. / Pedersen, Jesper Geert; Madsen, Anne Tranberg; Gammelgaard, Kristine Raaby et al.

    In: Cancers, Vol. 12, No. 6, 1414, 06.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Plasmacytoid Dendritic Cells as Cell-Based Therapeutics : A Novel Immunotherapy to Treat Human Immunodeficiency Virus Infection? / van der Sluis, Renée Marije; Egedal, Johanne Hovgaard; Jakobsen, Martin Roelsgaard.

    In: Frontiers in cellular and infection microbiology, Vol. 10, 249, 05.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  21. Published

    Diverse effects of interferon alpha on the establishment and reversal of HIV latency. / Van der Sluis, Renée M; Zerbato, Jennifer M; Rhodes, Jake W et al.

    In: PLOS Pathogens, Vol. 16, No. 2, e1008151, 2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Phenotypic and functional characterization of synovial fluid-derived fibroblast-like synoviocytes in rheumatoid arthritis. / Køster, Ditte; Egedal, J. H.; Hvid, M. et al.

    In: Annals of the Rheumatic Diseases, Vol. 79, No. Suppl.1, AB0100, 2020, p. 1345.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearchpeer-review

  23. Published

    Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling. / George, Ashley F.; Jang, Karen S.; Nyegaard, Mette et al.

    In: Human Reproduction, Vol. 35, No. 3, 2020, p. 617-640.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. 2019
  25. Published

    IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation. / Hotter, Dominik; Bosso, Matteo; Jønsson, Kasper L et al.

    In: Cell Host & Microbe, Vol. 25, No. 6, 06.2019, p. 858-872.e13.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins. / Braun, Elisabeth; Hotter, Dominik; Koepke, Lennart et al.

    In: Cell Reports, Vol. 27, No. 7, 14.05.2019, p. 2092-2104.e10.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. / Martin, Renata M; Ikeda, Kazuya; Cromer, M Kyle et al.

    In: Cell Stem Cell, Vol. 24, No. 5, 02.05.2019, p. 821-828.e5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Cellular Requirements for Sensing and Elimination of Incoming HSV-1 DNA and Capsids. / Sun, Chenglong; Luecke, Stefanie; Bodda, Chiranjeevi et al.

    In: Journal of Interferon and Cytokine Research, Vol. 39, No. 4, 2019, p. 191-204.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    cAIMP administration in humanized mice induces a chimerization-level-dependent STING response. / Andersen, Anna H.F.; Olesen, Rikke; Jønsson, Kasper L. et al.

    In: Immunology, Vol. 157, No. 2, 2019, p. 163-172.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. 2018
  31. Published

    Whole Exome Sequencing of HIV-1 long-term non-progressors identifies rare variants in genes encoding innate immune sensors and signaling molecules. / Nissen, Sara Konstantin; Christiansen, Mette; Helleberg, Marie et al.

    In: Scientific Reports, Vol. 8, No. 1, 15.10.2018, p. 15253.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage. / Dunphy, Gillian; Flannery, Sinéad M; Almine, Jessica F et al.

    In: Molecular Cell, Vol. 71, No. 5, 06.09.2018, p. 745-760.e5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function. / Laustsen, A; Bak, Rasmus; Krapp, Christian et al.

    In: Nature Communications, Vol. 9, No. 1, 3525, 30.08.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming. / Olagnier, David; Brandtoft, Aske M; Gunderstofte, Camilla et al.

    In: Nature Communications, Vol. 9, No. 1, 3506, 29.08.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling. / Hansen, Anne Louise; Buchan, Gregory J; Rühl, Michael et al.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 33, 14.08.2018, p. E7768-E7775.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Multiple Homozygous Variants in the STING-Encoding TMEM173 Gene in HIV Long-Term Nonprogressors. / Nissen, Sara K; Pedersen, Jesper G; Helleberg, Marie et al.

    In: Journal of Immunology, Vol. 200, No. 10, 15.05.2018, p. 3372-3382.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1. / Prabakaran, Thaneas; Bodda, Chiranjeevi; Krapp, Christian et al.

    In: E M B O Journal, Vol. 37, No. 8, E97858, 13.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    STING dependent sensing - Does HIV actually care? / Krapp, Christian; Jønsson, Kasper; Jakobsen, Martin R.

    In: Cytokine & Growth Factor Reviews, 04.2018, p. 68-76.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  39. Published

    Human cytomegalovirus tegument protein pp65 (pUL83) dampens type I interferon production by inactivating the DNA sensor cGAS without affecting STING. / Biolatti, Matteo; Dell'Oste, Valentina; Pautasso, Sara et al.

    In: Journal of Virology, Vol. 92, No. 6, e01774-17, 03.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    ERAdP standing in the shadow of STING innate immune signaling. / Jakobsen, Martin Roelsgaard.

    In: Nature Immunology, No. 19, 18.01.2018, p. 105-107.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  41. Published

    CD11c-targeted Delivery of DNA to Dendritic Cells Leads to cGAS- and STING-dependent Maturation. / Laursen, Marlene F; Christensen, Esben; Degn, Laura L T et al.

    In: Journal of Immunotherapy, Vol. 41, No. 1, 01.2018, p. 9-18.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    STING regulation in lung cancer. / Gammelgaard, Kristine Raaby; Paulsen, Birgitte Sandfeld; Demuth, Christina et al.

    2018. Poster session presented at Dansk Selskab for Cancerforskning Årsmøde.

    Research output: Contribution to conferencePosterResearch

  43. Published

    The Impact of genetic Variants of STING and IFI16 on Non-Small Cell Lung Cancer. / Gammelgaard, Kristine Raaby; Paulsen, Birgitte Sandfeld; Demuth, Christina et al.

    2018. Poster session presented at HOST-PATHOGEN COMMUNICATION MEETING 2018, Rehovot, Israel.

    Research output: Contribution to conferencePosterResearchpeer-review

  44. 2017
  45. Published

    cGAS is activated by DNA in a length-dependent manner. / Luecke, Stefanie; Holleufer, Andreas; Christensen, Maria H et al.

    In: E M B O Reports, Vol. 18, No. 10, 10.2017, p. 1707–1715.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP. / Jønsson, K L; Laustsen, A; Krapp, C et al.

    In: Nature Communications, Vol. 8, 14391, 10.02.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells. / Neidleman, Jason A; Chen, Joseph C; Kohgadai, Nargis et al.

    In: P L o S Pathogens, Vol. 13, No. 2, 02.2017, p. e1006163.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  48. 2016
  49. Published

    Inhibition of P2X receptors protects human monocytes against damage by leukotoxin from Aggregatibacter actinomycetemcomitans and α-hemolysin from Escherichia coli. / Fagerberg, Steen K; Jakobsen, Martin R; Skals, Marianne et al.

    In: Infection and Immunity, Vol. 84, No. 11, 15.11.2016, p. 3114-3130 .

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    Frequency and Env determinants of HIV-1 subtype C strains from antiretroviral therapy-naive subjects that display incomplete inhibition by maraviroc. / Borm, Katharina; Jakobsen, Martin R; Cashin, Kieran et al.

    In: Retrovirology, Vol. 13, No. 1, 74, 03.11.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. Published

    Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses. / Holm, Christian K; Rahbek, Stine H; Gad, Hans Henrik et al.

    In: Nature Communications, Vol. 7, 10680, 19.02.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  52. Published

    Friend or Foe : Innate Sensing of HIV in the Female Reproductive Tract. / Roan, Nadia R; Jakobsen, Martin R.

    In: Current HIV - AIDS Reports, Vol. 13, No. 1, 15.02.2016, p. 53-63.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Macrophage activation in HIV-2 infected patients is less affected by antiretroviral treatment - sCD163 in HIV-1, HIV-2 and HIV-1/2 dually infected patients. / HØnge, Bo L; Andersen, Morten N; Jespersen, Sanne et al.

    In: J A I D S, 27.01.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  54. Published

    Targeted, homology-driven gene insertion in stem cells by ZFN-loaded 'all-in-one' lentiviral vectors. / Cai, Yujia; Laustsen, Anders; Zhou, Yan et al.

    In: eLife, Vol. 5, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  55. 2015
  56. Published

    Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection. / Sun, Chenglong; Schattgen, Stefan A; Pisitkun, Prapaporn et al.

    In: Journal of Immunology, Vol. 194, No. 4, 15.02.2015, p. 1819-31.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. Published

    Histone Deacetylase Inhibitor Romidepsin Inhibits de novo HIV-1 Infections. / Jønsson, Kasper L; Tolstrup, Martin; Vad-Nielsen, Johan et al.

    In: Antimicrobial Agents and Chemotherapy, Vol. 59, No. 7, 2015, p. 3984-3994.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  58. 2014
  59. Published

    Innate immune sensing of HIV-1 infection. / Jakobsen, Martin Roelsgaard; Olagnier, David; Hiscott, John.

    In: Current Opinion in HIV and AIDS, 05.12.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  60. Published

    Differences in coreceptor specificity contribute to alternative tropism of HIV-1 subtype C for CD4 + T-cell subsets, including stem cell memory T-cells. / Cashin, Kieran; Paukovics, Geza; Jakobsen, Martin Roelsgaard et al.

    In: Retrovirology, Vol. 11, No. 1, 12.11.2014, p. 97.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  61. Published

    Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway. / Hansen, Kathrine; Prabakaran, Thaneas; Laustsen, Anders et al.

    In: E M B O Journal, Vol. 33, No. 15, 01.08.2014, p. 1654-66.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  62. Published

    IFI16 : At the interphase between innate DNA sensing and genome regulation. / Jakobsen, Martin Roelsgaard; Paludan, Søren R.

    In: Cytokine & Growth Factor Reviews, 21.06.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  63. Published

    Innate DNA sensing is impaired in HIV patients and IFI16 expression correlates to chronic immune activation. / Nissen, Sara K; Højen, Jesper Falkesgaard; Andersen, Karen L D et al.

    In: Clinical and Experimental Immunology, Vol. 177, No. 1, 05.03.2014, p. 295-309.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  64. Published

    Inflammatory Cytokines Break Down Intrinsic Immunological Tolerance of Human Primary Keratinocytes to Cytosolic DNA. / Chiliveru, Srikanth; Rahbek, Stine H; Jensen, Simon K et al.

    In: Journal of Immunology, 2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  65. Published

    Quantifying Susceptibility of CD4+ Stem Memory T-Cells to Infection by Laboratory Adapted and Clinical HIV-1 Strains. / Flynn, Jacqueline K; Paukovics, Geza; Cashin, Kieran et al.

    In: Viruses, Vol. 6, No. 2, 2014, p. 709-26.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  66. Published

    T Cells Detect Intracellular DNA but Fail to Induce Type I IFN Responses : Implications for Restriction of HIV Replication. / Berg, Randi K; Rahbek, Stine Hess; Kofod-Olsen, Emil et al.

    In: PLOS ONE, Vol. 9, No. 1, 2014, p. e84513.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  67. 2013
  68. Published

    IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication. / Jakobsen, Martin Roelsgaard; Bak, Rasmus O; Andersen, Annika et al.

    In: Proceedings of the National Academy of Sciences of the United States of America, 23.10.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  69. Published

    Linkages between HIV-1 specificity for CCR5 or CXCR4 and in vitro usage of alternative coreceptors during progressive HIV-1 subtype C infection. / Cashin, Kieran; Jakobsen, Martin Roelsgaard; Sterjovski, Jasminka et al.

    In: Retrovirology, Vol. 10, No. 1, 16.09.2013, p. 98.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  70. Published

    Proteasomal Degradation of Herpes Simplex Virus Capsids in Macrophages Releases DNA to the Cytosol for Recognition by DNA Sensors. / Horan, Kristy A; Hansen, Kathrine; Jakobsen, Martin Roelsgaard et al.

    In: Journal of Immunology, Vol. 190, No. 5, 01.03.2013, p. 2311-2329.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  71. Published

    CoRSeqV3-C : a novel HIV-1 subtype C specific V3 sequence based coreceptor usage prediction algorithm. / Cashin, Kieran; Gray, Lachlan R; Jakobsen, Martin Roelsgaard et al.

    In: Retrovirology, Vol. 10, No. 1, 2013, p. 24.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  72. Published

    Efficient sleeping beauty DNA transposition from DNA minicircles. / Sharma, Nynne; Cai, Yujia; Bak, Rasmus O et al.

    In: Molecular Therapy - Nucleic Acids, Vol. 2, 2013, p. e74.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  73. Published

    Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection. / Jakobsen, Martin Roelsgaard; Cashin, Kieran; Roche, Michael et al.

    In: P L o S One, Vol. 8, No. 6, 2013, p. e65950.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  74. 2012
  75. Published

    Caught in translation : innate restriction of HIV mRNA translation by a schlafen family protein. / Jakobsen, Martin Roelsgaard; Mogensen, Trine H; Paludan, Søren R.

    In: Cell Research, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  76. Published

    Impact of Minority Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutations on Resistance Genotype after Virologic Failure. / Li, Jonathan Z; Paredes, Roger; Ribaudo, Heather et al.

    In: The Internet Journal of Infectious Diseases, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  77. Published

    V3 determinants of HIV-1 escape from the CCR5 inhibitors Maraviroc and Vicriviroc. / Berro, Reem; Klasse, Per Johan; Jakobsen, Martin Roelsgaard et al.

    In: Virology, Vol. 427, No. 2, 2012, p. 158-65.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  78. Published

    Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING. / Holm, Christian K; Jensen, Søren B; Jakobsen, Martin Roelsgaard et al.

    In: Nature Immunology, Vol. 13, No. 8, 2012, p. 737-43.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  79. 2011
  80. Published

    Efficient Sleeping Beauty transposition from DNA minicircles. / Cai, Yujia; Sharma, Nynne; Jakobsen, Martin Roelsgaard et al.

    2011. Poster session presented at The annual congress of the European Society for Gene and Cell Therapy, Brighton, United Kingdom.

    Research output: Contribution to conferencePosterResearch

  81. Published

    HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropism. / Roche, Michael; Jakobsen, Martin Roelsgaard; Sterjovski, Jasminka et al.

    In: Indian Journal of Virology, Vol. 85, No. 9, 01.05.2011, p. 4330-42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  82. Published

    Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis. / Li, Jonathan Z; Paredes, Roger; Ribaudo, Heather J et al.

    In: JAMA: The Journal of the American Medical Association, Vol. 305, No. 13, 06.04.2011, p. 1327-35.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  83. Published

    Characterization of the virus-cell interactions by HIV-1 subtype C variants from an antiretroviral therapy-naïve subject with baseline resistance to the CCR5 inhibitor maraviroc. / Jakobsen, Martin Roelsgaard.

    2011. Poster session presented at Keystone Symposia - HIV Evolution, Genomics and Pathogenesis, Whistler, British Colombia, Canada.

    Research output: Contribution to conferencePosterResearchpeer-review

  84. Published

    HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry. / Roche, Michael; Jakobsen, Martin Roelsgaard; Ellett, Anne et al.

    In: Retrovirology, Vol. 8, 2011, p. 89.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  85. 2010
  86. Published

    Enhanced CD4+ cellular apoptosis by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with progressive HIV-1 infection. / Wade, Jessica; Sterjovski, Jasminka; Gray, Lachlan et al.

    In: Virology, Vol. 396, No. 2, 2010, p. 246-55.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  87. Published

    Transmission of HIV-1 Drug-Resistant Variants: Prevalence and Effect on Treatment Outcome. / Jakobsen, Martin R; Tolstrup, Martin; Søgaard, Ole S et al.

    In: Clinical Infectious Diseases, 2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  88. 2009
  89. Published

    HIV Viral Fitness. / McPhee, D; Arnott, A; Jakobsen, Martin Roelsgaard et al.

    2009. Poster session presented at 26th National Serology Reference Laboratory Workshop, New Zealand.

    Research output: Contribution to conferencePosterResearch

  90. Published

    Pre-screening HIV-1 reverse transcriptase resistance mutations in subtype B patients using a novel multiplex primer extension assay. / Jakobsen, Martin Roelsgaard; Aggerholm, Anni; Jørgensen, Louise Bruun et al.

    In: Current H I V Research, Vol. 7, No. 4, 2009, p. 398-409.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  91. Published

    Transmission of HIV-1 drug resistant variants: Prevalence and impact on treatment outcome. / Jakobsen, Martin Roelsgaard; Tolstrup, Martin; Søgaard, Ole Schmeltz et al.

    In: Clinical Infectious Diseases, 2009.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  92. Published

    Viral Tropism, Fitness and Pathogenicity of HIV-1 Subtype C. / Jakobsen, Martin Roelsgaard; Ellett, Anne; Churchill, Melissa et al.

    In: Future Virology, 2009.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  93. 2008
  94. Published

    C-reactive protein predicts future arterial and cardiovascular events in patients with symptomatic peripheral arterial disease. / Høgh, Annette Langager; Joensen, Jette; Lindholt, Jes S. et al.

    In: Vascular and Endovascular Surgery, Vol. 42, No. 4, 2008, p. 341-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  95. Published

    Entecavir therapy induces de novo HIV reverse-transcriptase M184V mutation in an antiretroviral therapy-naive patient. / Jakobsen, Martin Roelsgaard; Arildsen, Hanne; Krarup, Henrik B et al.

    In: Clinical Infectious Diseases, Vol. 46, No. 9, 2008, p. e88-91.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  96. Published

    HIV-1 Drug Resistance: Detection of Minority Resistant Variants. / Jakobsen, Martin Roelsgaard.

    Aarhus Universitet : Fællestrykkeriet, Det Sundshedsvidenskabelige Fakultet, Aarhus Universitet, 2008. 71 p.

    Research output: Book/anthology/dissertation/reportPh.D. thesis

  97. Published

    HIV-smitte udvikler resistens. / Jakobsen, Martin Roelsgaard.

    In: Berlingske Tidende, 2008.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperContribution to newspaper - Newspaper article

  98. 2007
  99. Published

    Comparative dynamics of HIV-1 drug resistance: linked 103K/N and 184M/V plasma viral versus CD45RO+ T cell proviral populations. / Jakobsen, Martin Roelsgaard; Bertelsen, Lone Skoubo; Laursen, Alex Lund et al.

    2007. Poster session presented at The Ph.D Day, Århus, Denmark.

    Research output: Contribution to conferencePosterResearch

  100. Published

    Dynamics of 103K/N and 184M/V HIV-1 drug resistant populations: relative comparison in plasma virus RNA versus CD45RO+T cell proviral DNA. / Jakobsen, Martin Roelsgaard; Tolstrup, M; Bertelsen, L et al.

    In: Journal of Clinical Virology, Vol. 39, No. 3, 2007, p. 215-21.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  101. Published

    Efficient inhibition of HIV-1 expression by LNA modified antisense oligonucleotides and DNAzymes targeted to functionally selected binding sites. / Jakobsen, Martin R; Haasnoot, Joost; Wengel, Jesper et al.

    In: Retrovirology, Vol. 4, No. 29, 2007, p. 1-13.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  102. Published

    SNaPshot of HIV Viral Drug Resistant Mutations: A novel assay for single-nucleotide polymorphism screening. / Jakobsen, Martin Roelsgaard; Aggerholm, Anni; Laursen, Alex Lund et al.

    2007. Poster session presented at The 11th European AIDS Clinical Society, Madrid, Spain.

    Research output: Contribution to conferencePosterResearch

  103. 2005
  104. Published

    In vitro Selection Strategy to Identify Antisense Target Sites in RNA or hnRNP Complexes: Application on HIV-1. / Kjems, Jørgen; Jakobsen, Martin Roelsgaard; Lützelberger, Martin.

    2005.

    Research output: Book/anthology/dissertation/reportReportResearch

  105. 2004
  106. Published

    A genomic selection strategy to identify accessible and dimerization blocking targets in the 5'-UTR of HIV-1 RNA. / Jakobsen, Martin R; Damgaard, Christian K; Andersen, Ebbe S et al.

    In: Nucleic Acids Research, Vol. 32, No. 7, 2004, p. e67.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review