Martin Kristian Thomsen

  1. Journal article
  2. Published

    cAIMP administration in humanized mice induces a chimerization-level-dependent STING response. / Andersen, Anna H.F.; Olesen, Rikke; Jønsson, Kasper L.; Højen, Jesper F.; Krapp, Christian; Mack, Katharina; Thomsen, Martin K.; Østergaard, Lars; Tolstrup, Martin; Dagnæs-Hansen, Frederik; Jakobsen, Martin R.; Denton, Paul W.

    In: Immunology, Vol. 157, No. 2, 2019, p. 163-172.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation. / Bakiri, Latifa; Hamacher, Rainer; Graña, Osvaldo; Guío-Carrión, Ana; Campos-Olivas, Ramón; Martinez, Lola; Dienes, Hans P; Thomsen, Martin K; Hasenfuss, Sebastian C; Wagner, Erwin F.

    In: Journal of Experimental Medicine, Vol. 214, No. 5, 05.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Pancreas specific expression of oncogenes in a porcine model. / Berthelsen, Martin Fogtmann; Callesen, Morten Møbjerg; Østergaard, Tanja Stenshøj; Liu, Ying; Li, Rong; Callesen, Henrik; Dagnæs-Hansen, Frederik; Hamilton Dutoit, Stephen Jacques; Jakobsen, Jannik E.; Thomsen, Martin Kristian.

    In: Transgenic Research, Vol. 26, No. 5, 2017, p. 603-612.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    A genetically inducible porcine model of intestinal cancer. / Callesen, Morten Møbjerg; Árnadóttir, Sigrid Salling; Lyskjær, Iben; Ørntoft, Mai-Britt Worm; Høyer, Søren; Dagnæs-Hansen, Frederik; Liu, Ying; Li, Rong; Callesen, Henrik; Rasmussen, Mads Heilskov; Berthelsen, Martin Fogtmann; Thomsen, Martin Kristian; Schweiger, Pawel Jan; Jensen, Kim Bak; Laurberg, Søren; Ørntoft, Torben Falck; Jakobsen, Jannik E.; Andersen, Claus Lindbjerg.

    In: Molecular Oncology, Vol. 11, No. 11, 11.2017, p. 1616-1629.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis. / Francis, Jeffrey C; McCarthy, Afshan; Thomsen, Martin K; Ashworth, Alan; Swain, Amanda.

    In: P L o S Genetics, Vol. 6, No. 6, 24.06.2010, p. e1000995.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma. / Francis, Jeffrey C; Thomsen, Martin K; Taketo, Makoto M; Swain, Amanda.

    In: P L o S Genetics, Vol. 9, No. 1, 2013, p. e1003180.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism. / Hasenfuss, Sebastian C; Bakiri, Latifa; Thomsen, Martin K; Hamacher, Rainer; Wagner, Erwin F.

    In: Hepatology, Vol. 59, No. 1, 01.2014, p. 261-73.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers. / Hasenfuss, Sebastian C; Bakiri, Latifa; Thomsen, Martin K; Williams, Evan G; Auwerx, Johan; Wagner, Erwin F.

    In: Cell Metabolism, Vol. 19, No. 1, 07.01.2014, p. 84-95.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Dominant negative SERPING1 variants cause intracellular retention of C1-inhibitor in hereditary angioedema. / Haslund, Didde; Ryø, Laura Barrett; Majidi, Sara Seidelin; Christiansen, Iben Rose; Skipper, Kristian Alsbjerg; Fryland, Tue; Bohn, Anja Bille; Koch, Claus; Thomsen, Martin Kristian; Palarasah, Yaseelan; Corydon, Thomas Juhl; Bygum, Anette; Nejsum, Lene Niemann; Mikkelsen, Jacob Giehm.

    In: Journal of Clinical Investigation, Vol. 129, No. 1, CI98869, 2019, p. 388-405.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses. / Holm, Christian K; Rahbek, Stine H; Gad, Hans Henrik; Bak, Rasmus O; Jakobsen, Martin R; Jiang, Zhaozaho; Hansen, Anne Louise; Jensen, Simon K; Sun, Chenglong; Thomsen, Martin K; Laustsen, Anders; Nielsen, Camilla G; Severinsen, Kasper; Xiong, Yingluo; Burdette, Dara L; Hornung, Veit; Lebbink, Robert Jan; Duch, Mogens; Fitzgerald, Katherine A; Bahrami, Shervin; Mikkelsen, Jacob Giehm; Hartmann, Rune; Paludan, Søren R.

    In: Nature Communications, Vol. 7, 10680, 19.02.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    An innate antiviral pathway acting before interferons at epithelial surfaces. / Iversen, Marie B; Reinert, Line S; Thomsen, Martin K; Bagdonaite, Ieva; Nandakumar, Ramya; Cheshenko, Natalia; Prabakaran, Thaneas; Vakhrushev, Sergey Y; Krzyzowska, Malgosha; Kratholm, Sine K; Ruiz-Perez, Fernando; Petersen, Steen V; Goriely, Stanislas; Bibby, Bo Martin; Eriksson, Kristina; Ruland, Jürgen; Thomsen, Allan R; Herold, Betsy C; Wandall, Hans H; Frische, Sebastian; Holm, Christian K; Paludan, Søren R.

    In: Nature Immunology, 30.11.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Intracellular bacteria engage a STING–TBK1–MVB12b pathway to enable paracrine cGAS–STING signalling. / Nandakumar, Ramya; Tschismarov, Roland; Meissner, Felix; Prabakaran, Thaneas; Krissanaprasit, Abhichart; Farahani, Ensieh; Zhang, Bao cun; Assil, Sonia; Martin, Amandine; Bertrams, Wilhelm; Holm, Christian K.; Ablasser, Andrea; Klause, Tanja; Thomsen, Martin K.; Schmeck, Bernd; Howard, Kenneth A.; Henry, Thomas; Gothelf, Kurt V.; Decker, Thomas; Paludan, Søren R.

    In: Nature Microbiology, Vol. 4, 04.2019, p. 701-713.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS. / Reinert, Line S; Lopušná, Katarína; Winther, Henriette; Sun, Chenglong; Thomsen, Martin K; Nandakumar, Ramya; Mogensen, Trine H; Meyer, Morten; Vægter, Christian; Nyengaard, Jens R; Fitzgerald, Katherine A; Paludan, Søren R.

    In: Nature Communications, Vol. 7, 13348, 10.11.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Virus delivery of CRISPR guides to the murine prostate for gene alteration. / Riedel, Maria; Berthelsen, Martin F.; Bakiri, Latifa; Wagner, Erwin F.; Thomsen, Martin K.

    In: Journal of Visualized Experiments, Vol. 134, e57525, 27.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice. / Skouboe, Morten K; Knudsen, Alice; Reinert, Line S; Boularan, Cedric; Lioux, Thierry; Perouzel, Eric; Thomsen, Martin K; Paludan, Søren R.

    In: P L o S Pathogens, Vol. 14, No. 4, e1006976, 02.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    JUNB/AP-1 controls IFN-γ during inflammatory liver disease. / Thomsen, Martin K; Bakiri, Latifa; Hasenfuss, Sebastian C; Hamacher, Rainer; Martinez, Lola; Wagner, Erwin F.

    In: Journal of Clinical Investigation, Vol. 123, No. 12, 12.2013, p. 5258-68.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection. / Thomsen, Martin K; Nandakumar, Ramya; Stadler, Daniela; Malo, Antje; Valls, Roser Marin; Wang, Fan; Reinert, Line S; Dagnaes-Hansen, Frederik; Hollensen, Anne Kruse; Mikkelsen, Jacob Giehm; Protzer, Ulrike; Paludan, Søren R.

    In: Hepatology, Vol. 64, No. 3, 16.06.2016, p. 746-759.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Loss of JUNB/AP-1 promotes invasive prostate cancer. / Thomsen, M K; Bakiri, L; Hasenfuss, Sebastian C; Wu, H.; Morente, M; Wagner, E F.

    In: Cell Death and Differentiation, Vol. 22, No. 4, 04.2015, p. 574-82.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation. / Thomsen, Martin K; Ambroisine, Laurence; Wynn, Sarah; Cheah, Kathryn S E; Foster, Christopher S; Fisher, Gabrielle; Berney, Daniel M; Møller, Henrik; Reuter, Victor E; Scardino, Peter; Cuzick, Jack; Ragavan, Narasimhan; Singh, Paras B; Martin, Francis L; Butler, Christopher M; Cooper, Colin S.; Swain, Amanda; Transatlantic Prostate Group.

    In: Cancer research, Vol. 70, No. 3, 01.02.2010, p. 979-87.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Sox9 is required for prostate development. / Thomsen, Martin K; Butler, Christopher M; Shen, Michael M; Swain, Amanda.

    In: Developmental Biology, Vol. 316, No. 2, 15.04.2008, p. 302-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    The cGAS-STING pathway is a therapeutic target in a preclinical model of hepatocellular carcinoma. / Thomsen, Martin K.; Skouboe, Morten K.; Boularan, Cedric; Vernejoul, Fabienne; Lioux, Thierry; Leknes, Siv L.; Berthelsen, Martin F.; Riedel, Maria; Cai, Huiqiang; Joseph, Justin V.; Perouzel, Eric; Tiraby, Michele; Vendelbo, Mikkel H.; Paludan, Søren R.

    In: Oncogene, Vol. 39, No. 8, 02.2020, p. 1652-1664.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    The role of Sox9 in prostate development. / Thomsen, Martin K; Francis, Jeffrey C; Swain, Amanda.

    In: Differentiation, Vol. 76, No. 6, 07.2008, p. 728-35.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    STEEP mediates STING ER exit and activation of signaling. / Zhang, Bao cun; Nandakumar, Ramya; Reinert, Line S.; Huang, Jinrong; Laustsen, Anders; Gao, Zong liang; Sun, Cheng long; Jensen, Søren Beck; Troldborg, Anne; Assil, Sonia; Berthelsen, Martin F.; Scavenius, Carsten; Zhang, Yan; Windross, Samuel J.; Olagnier, David; Prabakaran, Thaneas; Bodda, Chiranjeevi; Narita, Ryo; Cai, Yujia; Zhang, Cong gang; Stenmark, Harald; Doucet, Christine M.; Noda, Takeshi; Guo, Zheng; Goldbach-Mansky, Raphaela; Hartmann, Rune; Chen, Zhijian J.; Enghild, Jan J.; Bak, Rasmus O.; Thomsen, Martin K.; Paludan, Søren R.

    In: Nature Immunology, Vol. 21, No. 8, 01.08.2020, p. 868-879.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. E-pub ahead of print

    STEEP mediates STING ER exit and activation of signaling. / Zhang, Bao-Cun; Nandakumar, Ramya; Reinert, Line S; Huang, Jinrong; Laustsen, Anders; Gao, Zong-Liang; Sun, Cheng-Long; Jensen, Søren Beck; Troldborg, Anne; Assil, Sonia; Berthelsen, Martin F; Scavenius, Carsten; Zhang, Yan; Windross, Samuel J; Olagnier, David; Prabakaran, Thaneas; Bodda, Chiranjeevi; Narita, Ryo; Cai, Yujia; Zhang, Cong-Gang; Stenmark, Harald; Doucet, Christine M; Noda, Takeshi; Guo, Zheng; Goldbach-Mansky, Raphaela; Hartmann, Rune; Chen, Zhijian J; Enghild, Jan J; Bak, Rasmus O; Thomsen, Martin K; Paludan, Søren R.

    In: Nature Immunology, 20.07.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Conference abstract for conference
  27. Published

    The CRISPR-Cas9 Minipig. / Berthelsen, Martin Fogtmann; Møller, Simone; Callesen, Henrik; Dagnæs-Hansen, Frederik; Luo, Yonglun; Jakobsen, Jannik E.; Thomsen, Martin Kristian.

    2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearch